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1.发明授权Method and compositions for enhancing production of secondary metabolites using clustered biosynthetic genes 失效使用聚合生物合成基因增强次生代谢产物生产的方法和组合物
公开(公告)号：US5462862A
公开(公告)日：1995-10-31
申请号：US8688
申请日：1993-01-25
申请人： Martinus A. M. Groenen , Annemarie E. Veenstra , Pieter Van Solingen , Bertus P. Koekman , Lucia H. M. Van Der Voort , Juan F. Martin , Santiago Gutierrez , Bruno Diez , Emilio Alvarez , Jose L. Barredo , Christina Esmahan
发明人： Martinus A. M. Groenen , Annemarie E. Veenstra , Pieter Van Solingen , Bertus P. Koekman , Lucia H. M. Van Der Voort , Juan F. Martin , Santiago Gutierrez , Bruno Diez , Emilio Alvarez , Jose L. Barredo , Christina Esmahan
IPC分类号： C12N15/09 , C07H21/04 , C07K14/375 , C12N1/15 , C12N1/21 , C12N9/00 , C12N9/10 , C12N9/52 , C12N9/88 , C12N15/10 , C12N15/52 , C12N15/80 , C12P37/00 , C12Q1/68 , C12R1/04 , C12R1/82 , C12P21/06 , C07H17/00 , C12N1/20 , C12N15/00
CPC分类号： C07K14/375 , C12N15/1034 , C12N15/52 , C12N15/80 , C12N9/1029 , C12N9/88 , C12P37/00
摘要： Clustered antibiotic biosynthetic genes are employed for improvement of production of the antibiotic in microorganisms and for the isolation of other genes involved in the biosynthesis of the antibiotic. The invention is exemplified with improved production of penicillin in Penicillium chrysogenum, with the isolation of another clustered biosynthetic gene(s) and with the expression of penicillin biosynthetic genes in Acremonium chrysogenum.
摘要翻译： 聚簇抗生素生物合成基因用于改善微生物中抗生素的生产和用于分离参与抗生素生物合成的其它基因。 本发明通过改良产黄青霉菌的生产得到例证，其中分离另一个聚集的生物合成基因，并与产黄青霉菌中的青霉素生物合成基因的表达。
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公开(公告)号：US20140034553A1
公开(公告)日：2014-02-06
申请号：US14110570
申请日：2012-03-09
IPC分类号： C10G1/04
CPC分类号： C10G1/045 , B01D3/009 , C10G1/04 , C10G2300/44 , C10G2300/80 , C10G2300/805
摘要： The present disclosure relates to a method of processing a bituminous feed. The bituminous feed is contacted with a bridging liquid-in-extraction liquor emulsion to form a slurry. Solids in the slurry are agglomerated, using agitation, to form an agglomerated slurry comprising agglomerated solids and a low solids bitumen extract. The agglomerates are then separated from the low solids bitumen extract. Emulsifying the bridging liquid prior to contacting it with the oil sands may reduce the amount of energy required for the agglomeration process. Other potential benefits may include the production of smaller and more uniform agglomerates. The former may lead to higher bitumen recoveries and the latter may improve the solid-liquid separation rate.
摘要翻译： 本公开涉及一种处理沥青进料的方法。 沥青进料与桥接液体萃取液体乳液接触以形成浆料。 浆料中的固体在搅拌下凝聚，形成包含附聚固体和低固体沥青提取物的附聚浆料。 然后将聚集体与低固体沥青提取物分离。 在与油砂接触之前将桥接液体乳化可能会减少聚集过程所需的能量。 其他潜在的好处可能包括生产较小和更均匀的附聚物。 前者可能导致更高的沥青回收率，后者可能提高固液分离速率。
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3.发明申请Systems and Methods For Hydrotreating A Shale Oil Stream Using Hydrogen Gas That Is Concentrated From The Shale Oil Stream 审中-公开使用从页岩油流中浓缩的氢气加氢处理页岩油流的系统和方法公开(公告)号：US20130319662A1
公开(公告)日：2013-12-05
申请号：US13888704
申请日：2013-05-07
CPC分类号： E21B36/008 , C10G1/002 , C10G1/02 , C10G49/22 , C10G70/046 , C10G2300/4037 , E21B43/24
摘要： Systems and methods for hydrotreating a liquid fraction of a shale oil stream using hydrogen gas that is concentrated from a gaseous fraction of the shale oil stream. The systems and methods include providing a portion of the gaseous fraction to a sorptive separation assembly and separating a concentrated hydrogen stream from the portion of the gaseous fraction within the sorptive separation assembly. The system and methods further include providing the concentrated hydrogen stream and the liquid fraction to a hydrotreater and reacting the concentrated hydrogen stream with the liquid fraction within the hydrotreater to produce the hydrotreated liquid stream. The systems and methods may include generating the shale oil stream within a subterranean formation using an in situ process, such as an in situ shale oil conversion process and/or providing a supplemental hydrogen stream to the hydrotreater.
摘要翻译： 使用从页岩油流的气体部分浓缩的氢气加氢处理页岩油流的液体馏分的系统和方法。 该系统和方法包括将一部分气态馏分提供给吸附分离组件，并将浓缩的氢气流与吸附分离组件内气态馏分的部分分离。 该系统和方法还包括将浓缩的氢气流和液体馏分提供给加氢处理器，并使浓缩的氢流与加氢处理器内的液体馏分反应以产生加氢处理的液体流。 系统和方法可以包括使用原位过程（例如原位页岩油转化方法）和/或向加氢处理器提供补充氢气流，在地层内产生页岩油流。
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公开(公告)号：US20140076784A1
公开(公告)日：2014-03-20
申请号：US14113207
申请日：2012-03-09
申请人： Brian C. Speirs , Olusola B. Adeyinka , Thomas R. Palmer , Emilio Alvarez , Anjaneya S. Kovvali , David C. Rennard , Fritz Pierre, JR.
发明人： Brian C. Speirs , Olusola B. Adeyinka , Thomas R. Palmer , Emilio Alvarez , Anjaneya S. Kovvali , David C. Rennard , Fritz Pierre, JR.
IPC分类号： C10G1/04
CPC分类号： C10G1/045 , C10G1/04 , C10G1/047 , C10G33/08 , C10G2300/1033 , C10G2300/4081 , C10G2300/44 , C10G2300/805
摘要： Described herein is a method of processing a bituminous feed. The bituminous feed is contacted with an extraction liquor to form a slurry. A bridging liquid is added to the slurry, and, solids are agitated within the slurry to form an agglomerated slurry comprising agglomerates and a low solids bitumen extract. In order to control agglomeration, the slurry is analyzed and the processing method is adjusted accordingly.
摘要翻译： 本文描述了一种处理沥青进料的方法。 沥青进料与萃取液接触以形成浆料。 将桥接液体加入到浆料中，并且在浆料内搅拌固体以形成包含附聚物和低固体沥青提取物的附聚浆料。 为了控制凝聚，对浆料进行分析，相应调整处理方法。
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公开(公告)号：US20130056395A1
公开(公告)日：2013-03-07
申请号：US13643540
申请日：2011-05-20
申请人： Fritz Pierre, JR. , Olusola Adeyinka , Brian C. Speirs , Emilio Alvarez , Payman Esmaeili , Ronald D. Myers , Robert D. Kaminsky , Justin D. Pace , Thomas R. Palmer , David C. Rennard , Mainak Ghosh
发明人： Fritz Pierre, JR. , Olusola Adeyinka , Brian C. Speirs , Emilio Alvarez , Payman Esmaeili , Ronald D. Myers , Robert D. Kaminsky , Justin D. Pace , Thomas R. Palmer , David C. Rennard , Mainak Ghosh
CPC分类号： C10G1/002 , C10G1/04 , C10G1/047 , C10G33/00 , C10G33/04 , C10G33/06 , C10G2300/206 , C10G2300/44 , C10G2300/80 , C10G2300/805
摘要： Processes are described for extracting hydrocarbon from a mineable deposit, such as bitumen from oil sands. The integration of solvent-based extraction processes with aqueous extraction processes is described. In one embodiment, water is removed from an aqueous bituminous feed that is then directed into a solvent-based extraction process. In another embodiment, a stream produced through solvent extraction is directed into a water-based extraction process. In the solvent-based extraction processes, agglomeration of fines may be employed to simplify subsequent solid-liquid separation. The process permits recovery of hydrocarbon that has conventionally may have been too difficult to recover from oil sands processing, and thus has previously been lost. Advantageously, a fungible product can be formed more efficiently according to certain integrated processes described herein.
摘要翻译： 描述了从可开采沉积物中提取碳氢化合物的方法，如来自油砂的沥青。 描述了溶剂型萃取方法与含水萃取方法的结合。 在一个实施方案中，从含水沥青进料中除去水，然后将其导入基于溶剂的萃取方法中。 在另一个实施方案中，将通过溶剂萃取产生的流引导到水基萃取过程中。 在基于溶剂的萃取方法中，可以使用细粒团聚以简化随后的固液分离。 该方法允许回收常规可能难以从油砂处理中回收的烃，因此先前已经丢失。 有利地，可以根据本文所述的某些综合方法更有效地形成可替代的产品。
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6.发明申请Method of Processing a Bituminous Feed By Staged Addition of a Bridging Liquid 审中-公开通过分段添加桥接液处理沥青进料的方法公开(公告)号：US20140262964A1
公开(公告)日：2014-09-18
申请号：US14112203
申请日：2012-03-09
申请人： Lu Han , Brian C. Speirs , Olusola B. Adeyinka , Thomas R. Palmer , Emilio Alvarez , Anjaneya S. Kovvali , David C. Rennard , Fritz Pierre, JR.
发明人： Lu Han , Brian C. Speirs , Olusola B. Adeyinka , Thomas R. Palmer , Emilio Alvarez , Anjaneya S. Kovvali , David C. Rennard , Fritz Pierre, JR.
IPC分类号： C10G1/04
CPC分类号： C10G1/045 , C10G1/04 , C10G2300/44 , C10G2300/805
摘要： The present disclosure relates to a method of processing a bituminous feed. The bituminous feed is contacted with an extraction liquor to form a slurry. A bridging liquid is added to the slurry in at least two stages and solids within the slurry are agitated to form an agglomerated slurry comprising agglomerated solids and a low solids bitumen extract. The agglomerates are then separated from the low solids bitumen extract. Potential benefits may include the production of smaller and more uniform agglomerates. The former may lead to higher bitumen recoveries and the latter may improve the solid-liquid separation rate. The bridging liquid may be added in an area of relatively high shear rates. Between stages of bridging liquid addition, agglomerates may be removed.
摘要翻译： 本公开涉及一种处理沥青进料的方法。 沥青进料与萃取液接触以形成浆料。 将桥连液体至少两个阶段加入到浆料中，搅拌浆料内的固体以形成包含附聚固体和低固体沥青提取物的附聚浆料。 然后将聚集体与低固体沥青提取物分离。 潜在的益处可能包括生产更小和更均匀的团块。 前者可能导致更高的沥青回收率，后者可能提高固液分离速率。 桥接液体可以在相对高的剪切速率的区域中加入。 在桥接液体添加的阶段之间，可以除去附聚物。
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7.发明申请公开(公告)号：US20140209512A1
公开(公告)日：2014-07-31
申请号：US14236052
申请日：2012-08-08
IPC分类号： C10G1/04
摘要： Described is a method of processing a bituminous feed. The bituminous feed is solvent extracted to form a bitumen-rich stream and a bitumen-lean stream. Solvent is recovered from the bitumen-rich stream to form a bitumen product. Solvent and water are recovered from the bitumen-lean stream to form dry tailings with a moisture content of less than 40 wt.%. The dry tailings are separated into at least two streams, each stream having a moisture content of less than 40 wt. %, based on at least one physical or chemical property. At least one of the at least two streams is then used at an oil sands mine site. In this way, the dry tailings may be used more effectively.
摘要翻译： 描述了一种处理沥青进料的方法。 沥青进料被溶剂萃取以形成富含沥青的料流和贫沥青料流。 从富含沥青的流中回收溶剂以形成沥青产物。 从贫沥青料流中回收溶剂和水以形成水分含量低于40重量％的干尾矿。 将干尾矿分离成至少两股，每条料流的含水量小于40wt。 基于至少一种物理或化学性质。 然后在油砂矿场使用至少两条流中的至少一条。 以这种方式，可以更有效地使用干尾矿。
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8.发明申请公开(公告)号：US20140054201A1
公开(公告)日：2014-02-27
申请号：US14112552
申请日：2012-03-09
申请人： Olusola B. Adeyinka , Brian C. Speirs , Fritz Pierre, JR. , Payman Esmaeili , Emilio Alvarez , Anjaneya S. Kovvali , Thomas R. Palmer
发明人： Olusola B. Adeyinka , Brian C. Speirs , Fritz Pierre, JR. , Payman Esmaeili , Emilio Alvarez , Anjaneya S. Kovvali , Thomas R. Palmer
IPC分类号： C10G1/04
CPC分类号： C10G1/045 , B01D21/01 , B01D21/32 , C10G1/04 , C10G21/003 , C10G2300/44 , C10G2300/805
摘要： The present disclosure relates to a method of processing a bituminous feed. The bituminous feed is contacted with an extraction liquor to form a slurry. The slurry is then flowed through a pipeline. A bridging liquid is added to the slurry to assist agglomeration. Agitation is also used to assist agglomeration. The result is an agglomerated slurry comprising agglomerates and a low solids bitumen extract. The agglomerates are then separated from the low solids bitumen extract. Performing the agglomeration in a pipeline as opposed to in a conventional agitating vessel may provide certain advantages, such as improved sealing in order to contain the potentially flammable mixture of oil sands slurry from the atmosphere, production of smaller and more uniform agglomerates due to improved mixing of the bridging liquid into the oil sands slurry, and the flexibility to have a long residence time for the extraction and agglomeration processes.
摘要翻译： 本公开涉及一种处理沥青进料的方法。 沥青进料与萃取液接触以形成浆料。 然后将浆料流过管道。 将桥连液体加入到浆料中以辅助凝聚。 搅拌也用于辅助凝聚。 其结果是包含附聚物和低固体沥青提取物的聚集浆料。 然后将聚集体与低固体沥青提取物分离。 与常规搅拌容器相比，在管道中进行凝聚可以提供某些优点，例如改进的密封以便容纳来自大气的油砂浆料的潜在可燃混合物，由于改进的混合产生更小和更均匀的附聚物 的桥接液体进入油砂浆料，并且具有用于萃取和附聚过程的长停留时间的柔性。
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