Liquid aspirating method
    1.
    发明授权
    Liquid aspirating method 失效
    液体抽吸法

    公开(公告)号:US5488874A

    公开(公告)日:1996-02-06

    申请号:US211802

    申请日:1994-07-05

    IPC分类号: G01N1/00 G01N35/10

    摘要: The present invention aims to shorten an aspiration time, when aspirating a red blood cell component of a liquid sample having high viscosity. When aspirating the red blood cell component of a blood sample through a nozzle tip, a piston is pulled at its maximum to produce a maximum aspirating force, and starts aspiration. When a pressure in an aspirating system becomes equal to a predetermined value .alpha., the piston is returned to a position in which only a necessary aspiration volume of the liquid sample can be aspirated. Since the maximum aspirating force of the pump is utilized during the aspiration, the aspirating operation can be carried out more quickly.

    摘要翻译: PCT No.PCT / JP92 / 01344 Sec。 371日期:1994年7月5日 102(e)日期1994年7月5日PCT提交1992年10月15日PCT公布。 公开号WO93 / 08476 日期:1993年04月29日。本发明旨在缩短吸液时具有高粘度的液体样品的红细胞成分。 当通过喷嘴尖吸出血液样本的红细胞成分时,将活塞拉至最大值以产生最大抽吸力,并开始抽吸。 当抽吸系统中的压力变得等于预定值α时,活塞返回到只能抽吸液体样本的必要抽吸体积的位置。 由于在抽吸期间利用泵的最大抽吸力,所以可以更快地进行抽吸操作。

    Pipetting apparatus
    2.
    发明授权
    Pipetting apparatus 失效
    移液器

    公开(公告)号:US5488854A

    公开(公告)日:1996-02-06

    申请号:US295691

    申请日:1994-10-17

    IPC分类号: G01F23/14 G01N35/10 G01N7/00

    摘要: The presence of air bubbles is detected during a dispensing of samples for determining if the volume of the sample dispensed is insufficient.The characteristic of a presence-of-bubbles curve (101) has a difference in a pressure inside a nozzle from the characteristic of a curve (100) under a normal condition in which no bubbles exist, at the time just before the dispensing of the sample is completed. Accordingly, it is possible to determine whether or not bubbles exist by detecting the pressure inside the nozzle at the determination time (105) and comparing the detected value with an established threshold value, and it is determined that an insufficient volume of sample has been dispensed, thereby a warning is generated.

    摘要翻译: PCT No.PCT / JP92 / 01681 Sec。 371日期:1994年10月17日 102(e)日期1994年10月17日PCT提交1992年12月22日PCT公布。 公开号WO93 / 18409 日期为1993年9月16日。在分配样品期间检测到气泡的存在,以确定分配的样品的体积是否不足。 存在气泡曲线(101)的特征在正好在没有气泡存在的正常条件下,喷嘴内部的压力与曲线(100)的特性之间在分配前 样品完成。 因此,可以通过在确定时间(105)检测喷嘴内部的压力并将检测值与建立的阈值进行比较来确定是否存在气泡,并且确定已经分配了不足的样本体积 ,从而产生警告。

    Pipetting apparatus with clot detection
    3.
    发明授权
    Pipetting apparatus with clot detection 失效
    具有凝块检测的移液装置

    公开(公告)号:US5540081A

    公开(公告)日:1996-07-30

    申请号:US416833

    申请日:1995-05-15

    IPC分类号: G01N35/10 G01B13/00

    摘要: A pipetting apparatus is provided with clot detection. The pipetting apparatus comprises a nozzle for aspirating a sample. A pressure sensor is connected with the nozzle for measuring pressure in said nozzle. A plurality of pressure difference calculating circuits are operatively connected with the pressure sensor, each for inputting an output of said pressure sensor and obtaining a pressure difference at a different pressure calculation period, respectively. A plurality of discriminating circuits each having a different discrimination threshold value determined according to each of the pressure calculation periods are provided. An alarm circuit is included for outputting a clot detection alarm signal when at least one of said discriminating circuits discriminates that the obtained pressure difference exceeds the discrimination threshold value.

    摘要翻译: PCT No.PCT / JP93 / 01227 Sec。 371日期1995年5月15日 102(e)日期1995年5月15日PCT提交1993年8月31日PCT公布。 公开号WO95 / 06878 日期:1995年3月9日。移液器具有凝块检测。 移液装置包括用于抽吸样品的喷嘴。 压力传感器与喷嘴连接,用于测量所述喷嘴中的压力。 多个压力差计算电路与压力传感器可操作地连接,每个压力传感器用于输入所述压力传感器的输出并分别在不同的压力计算周期获得压力差。 提供了各自具有根据每个压力计算周期确定的不同鉴别阈值的多个识别电路。 当所述鉴别电路中的至少一个鉴别所获得的压差超过鉴别阈值时,包括报警电路,用于输出凝块检测报警信号。

    Method for pipetting a blood sample
    4.
    发明授权
    Method for pipetting a blood sample 失效
    吸取血样的方法

    公开(公告)号:US5452619A

    公开(公告)日:1995-09-26

    申请号:US211382

    申请日:1994-07-05

    摘要: In pipetting a blood plasma component and a red blood cell component separated vertically in a blood sample by a centrifugation, the red blood cell component having a high viscosity is aspirated as quickly as possible. A nozzle 32 is composed of a nozzle base 35 and a disposable tip 36, and is transferred upwardly and downwardly and to the right and left by an XYZ robot 34. At first the blood plasma component in the blood sample put in a test tube 62 is pipetted by a nozzle 32, and then an inner wall of the disposable tip 36 is coated with the blood plasma component, and thereafter the red blood component is pipetted.

    摘要翻译: PCT No.PCT / JP92 / 01281 Sec。 371日期:1994年7月5日 102(e)1994年3月31日PCT提交1992年10月2日PCT公布。 出版物WO93 / 07494 日期:1993年04月15日。在移取通过离心在血液样品中垂直分离的血浆成分和红细胞成分的情况下,尽快吸出具有高粘度的红细胞成分。 喷嘴32由喷嘴基座35和一次性尖端36构成,并通过XYZ机器人34向上下方向左右移动。首先,将血液试样中的血浆成分放入试管62 由喷嘴32吸移,然后用血浆成分涂覆一次性头部36的内壁,之后吸移血液成分。

    Automatic pipetting apparatus with leak detection and method of
detecting a leak
    5.
    发明授权
    Automatic pipetting apparatus with leak detection and method of detecting a leak 失效
    具有泄漏检测的自动移液装置和检测泄漏的方法

    公开(公告)号:US5537880A

    公开(公告)日:1996-07-23

    申请号:US481677

    申请日:1995-06-07

    IPC分类号: G01M3/26 G01N35/10

    摘要: Embodiments described herein provide a pipetting apparatus with leak detection and a method for detecting a leak. In one embodiment, an automatic pipetting apparatus comprises a nozzle having a lower end portion through which a fluid sample is aspirated and dispensed by changes in air pressure supplied to the nozzle. A piping system operatively connects the nozzle to a pump for supplying the air pressure to the nozzle. A pressure sensor is operatively connected with the piping system for measuring internal pressure in the piping system. An XYZ robot is operatively connected with the nozzle for three-dimensionally moving the nozzle between an aspirating position of the fluid sample and a dispensing position. A leak detector is operatively connected with the pressure sensor for detecting a leak in the piping system based upon a measured result obtained by measuring the internal pressure in the piping system with the pressure sensor while the nozzle, which has aspirated a predetermined volume of the fluid sample, is being moved between the aspirating position and the dispensing position by the robot.

    摘要翻译: 本文所述的实施例提供了具有泄漏检测的移液装置和用于检测泄漏的方法。 在一个实施例中,自动移液装置包括具有下端部分的喷嘴,通过该下端部抽吸流体样品并通过供给喷嘴的空气压力的变化来分配。 管道系统将喷嘴可操作地连接到泵,以将空气压力提供给喷嘴。 压力传感器与管道系统可操作地连接,用于测量管道系统中的内部压力。 XYZ机器人与喷嘴可操作地连接,用于在流体样品的抽吸位置和分配位置之间三维地移动喷嘴。 泄漏检测器与压力传感器可操作地连接,用于基于通过用压力传感器测量管道系统中的内部压力而获得的测量结果来检测管道系统中的泄漏,同时吸入预定体积的流体 样品由机器人在抽吸位置和分配位置之间移动。

    Semiconductor light emitting device and method of manufacturing the same
    6.
    发明申请
    Semiconductor light emitting device and method of manufacturing the same 有权
    半导体发光器件及其制造方法

    公开(公告)号:US20050189556A1

    公开(公告)日:2005-09-01

    申请号:US11047666

    申请日:2005-02-02

    CPC分类号: H01L33/20 H01L33/08 H01L33/46

    摘要: A semiconductor light emitting device comprises: a substrate having first and second major surfaces; a light emitting layer provided in a first portion on the first major surface of the substrate; a first electrode provided above the light emitting layer; a second electrode provided in a second portion on the first major surface of the substrate, the second portion being different from the first portion; and a protrusion provided on the second major surface of the substrate, the protrusion having a planar shape that reflects a planar shape of a light emitting area of the light emitting layer, the light emitting area being sandwiched between the first electrode and the second electrode and facing the protrusion.

    摘要翻译: 一种半导体发光器件包括:具有第一和第二主表面的衬底; 设置在所述基板的所述第一主表面上的第一部分中的发光层; 设置在所述发光层上方的第一电极; 设置在所述基板的所述第一主表面上的第二部分中的第二电极,所述第二部分不同于所述第一部分; 以及设置在所述基板的所述第二主表面上的突起,所述突起具有反映所述发光层的发光区域的平面形状的平面形状,所述发光区域夹在所述第一电极和所述第二电极之间, 面对突起。