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    Cast-iron thixocasting apparatus and method
    1.
    发明申请
    Cast-iron thixocasting apparatus and method 审中-公开
    铸铁触媒装置及方法

    公开(公告)号：US20070012415A1

    公开(公告)日：2007-01-18

    申请号：US10569511

    申请日：2004-08-24

    申请人： Masayuki Tsuchiya ,  Hiroaki Ueno ,  Chiaki Ushigome ,  Toshiro Maekawa ,  Syuichi Shikai

    发明人： Masayuki Tsuchiya ,  Hiroaki Ueno ,  Chiaki Ushigome ,  Toshiro Maekawa ,  Syuichi Shikai

    IPC分类号： B22D17/10

    CPC分类号： B22C9/06 ,  B22D17/007

    摘要： Disclosed is an apparatus for and a method of thixocasting a cast iron, that can effectively prevent the scale from mixing in the die (cavity) thereby to obtain sound iron castings having good mechanical properties. The apparatus includes at least a pair of dies that can freely opened and closed to define a cavity to be filled under a pressure, and an injector that injects the semi-molten iron into the cavity through a hole in a gate at the entry of the cavity so as to throttle the entry. The gate is a separate member disposed at the entry of the cavity every time an injection casting operation is carried out and is taken out together with the casting after the injection casting operation.

    摘要翻译： 本发明公开了一种能够有效地防止鳞片在模具（空腔）中混合从而获得具有良好机械性能的铁铸件的铸铁镶嵌装置和方法。 该装置包括至少一对可以自由地打开和关闭以限定要在压力下填充的空腔的模具;以及喷射器，其通过门中的孔将半熔融铁注入空腔中 以便节流入口。 闸门是每次执行注射操作时设置在空腔入口处的单独构件，并且在注射铸造操作之后与铸件一起取出。

    Injection mold for semi-solidified Fe alloy
    3.
    发明授权
    Injection mold for semi-solidified Fe alloy 有权
    半固态Fe合金注塑模具

    公开(公告)号：US06810941B2

    公开(公告)日：2004-11-02

    申请号：US10158580

    申请日：2002-05-30

    申请人： Masayuki Tsuchiya ,  Hiroaki Ueno ,  Isamu Takagi ,  Naokuni Muramatsu ,  Masato Yasuda

    发明人： Masayuki Tsuchiya ,  Hiroaki Ueno ,  Isamu Takagi ,  Naokuni Muramatsu ,  Masato Yasuda

    IPC分类号： B22C300

    CPC分类号： B22D17/2209 ,  B22D17/007

    摘要： An injection mold for casting a semi-solidified Fe alloy includes a scalping gate for eliminating surface oxide film of a semi-solidified Fe alloy injected into the mold cavity from a pressure chamber. The scalping gate is arranged between the pressure chamber and a runner that is in communication with the mold cavity. The mold halves and the scalping gate are each formed of a copper alloy having a thermal conductivity of not less than 120 W/(m·K) and a hardness of not less than 180 HB. The mold halves and the scalping gate each have a cermet layer consisting essentially of at least one member selected from a group consisting of Co, Cu, Cr and Ni. The cermet layer is formed by electro-spark deposition, via an intermediate layer of Ni alloy, which is also formed by electro-spark deposition.

    摘要翻译： 用于铸造半固化Fe合金的注射模具包括用于消除从压力室注入到模腔中的半固化Fe合金的表面氧化膜的刮刀。 烫平门布置在压力室和与模腔连通的转轮之间。 半模和烫金闸门均由热导率不低于120W /（m.K），硬度不低于180HB的铜合金形成。 模具半部和剥皮门各自具有金属陶瓷层，金属陶瓷层基本上由选自Co，Cu，Cr和Ni中的至少一种构成。 金属陶瓷层通过电火花沉积，通过也由电火花沉积形成的Ni合金中间层形成。

    Fe alloy material for thixocasting and method for heating the same
    4.
    发明授权
    Fe alloy material for thixocasting and method for heating the same 有权
    Fe合金材料用于触媒和加热它的方法

    公开(公告)号：US06616777B1

    公开(公告)日：2003-09-09

    申请号：US09508458

    申请日：2000-03-10

    申请人： Masayuki Tsuchiya ,  Hiroaki Ueno

    发明人： Masayuki Tsuchiya ,  Hiroaki Ueno

    IPC分类号： C22C3700

    CPC分类号： C21D6/008 ,  B22D17/007 ,  C21D6/00 ,  C22C37/10 ,  C22C38/02 ,  C22C38/04 ,  C22C38/08

    摘要： A thixocast Fe-based alloy material is provided, from which a cast product having mechanical properties uniform over the whole thereof can be produced. The Fe-based alloy material comprises 1.8% by weight≦C≦2.5% by weight, 1.0% by weight≦Si≦3.0% by weight, 0.1% by weight≦Mn≦1.5% by weight, 0.5% by weight≦Ni≦3.0% by weight, and as the balance, iron (Fe) including inevitable impurities. The eutectic crystal amount Ec is in a range of 10% by weight

    摘要翻译： 提供了一种触变Fe基合金材料，由此可以生产出具有整体机械性能均匀的铸造产品.Fe基合金材料包含1.8重量％<= C <2.5重量％，1.0 重量百分比<= Si <= 3.0％重量，0.1％（重量）<= Mn <= 1.5％（重量），0.5％（重量）

    Method of producing a nucleic acid encoding an antibody
    9.
    发明授权
    Method of producing a nucleic acid encoding an antibody 失效
    生产编码抗体的核酸的方法

    公开(公告)号：US08008076B2

    公开(公告)日：2011-08-30

    申请号：US11587701

    申请日：2005-04-27

    申请人： Masayuki Tsuchiya ,  Masami Suzuki ,  Kenji Yoshida ,  Etsuko Fujii ,  Miho Watanabe ,  Koichi Matsubara ,  Yu Jau Chen ,  Juliana Sim

    发明人： Masayuki Tsuchiya ,  Masami Suzuki ,  Kenji Yoshida ,  Etsuko Fujii ,  Miho Watanabe ,  Koichi Matsubara ,  Yu Jau Chen ,  Juliana Sim

    IPC分类号： C12N15/63 ,  C12N5/06 ,  C12N1/20 ,  C07H21/04

    CPC分类号： A01K67/027 ,  A01K2267/01 ,  A61K35/16 ,  C07K16/00 ,  C07K16/30

    摘要： An objective of the present invention is to facilitate the acquisition of antibody-producing cells that are infiltrating virus-infected cells, cancer cells, abnormal cells forming a benign hyperplasia, and the like, and to improve the efficiency of the production of antibodies as well as nucleic acids encoding them from the antibody-producing cells.The present inventors discovered that, when cancer tissues comprising infiltrating lymphocytes are transplanted into highly immunodeficient animals that do not have T cells, B cells, and NK cells and further exhibit a low IFN production ability, the differentiation and proliferation of infiltrating lymphocytes are unexpectedly promoted, and the number of plasma cells that produce antibodies recognizing cancer tissues increases dramatically, plasma cells can be separated easily, and antibodies or nucleic acids encoding them can be easily prepared from the plasma cells.

    摘要翻译： 本发明的目的是便于获得渗透病毒感染细胞的抗体产生细胞，癌细胞，形成良性增生的异常细胞等，以及提高抗体生产的效率 作为从抗体产生细胞编码它们的核酸。 本发明人发现，当将包含浸润性淋巴细胞的癌组织移植到不具有T细胞，B细胞和NK细胞的高度免疫缺陷的动物中并且进一步表现出低的IFN产生能力时，意外地促进了浸润性淋巴细胞的分化和增殖 并且产生识别癌组织的抗体的浆细胞的数量急剧增加，可以容易地分离浆细胞，并且可以容易地从浆细胞制备抗体或编码它们的核酸。