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公开(公告)号：US20230123613A1
公开(公告)日：2023-04-20
申请号：US17501292
申请日：2021-10-14
Applicant: Medtronic MiniMed, Inc.
Inventor： Ashwin K. Rao , Quyen B. Ong , Michael E. Miller , Sarnath Chattaraj , Guangping Zhang , Poonam Gulati , Ariel Reider , Mohsen Askarinya , Michael N. Missaghi , Chi-En Lin , Xin Heng , Inthirai Somasuntharam , Melissa Tsang , Carlos E. Maldonado , Akhil Srinivasan
IPC: G01N27/327 , C12N9/04 , C12Q1/00 , G01N33/49
Abstract: The invention provides amperometric analyte sensor systems comprising one or more electrodes designed to monitor in vivo levels of 3-hydroxybutyrate (and optionally glucose as well) in order to facilitate the management of diabetic ketoacidosis. The invention further includes compositions, elements and methods useful with such amperometric analyte sensor systems.
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公开(公告)号：US20210189450A1
公开(公告)日：2021-06-24
申请号：US16725957
申请日：2019-12-23
Applicant: Medtronic MiniMed, Inc.
Inventor： Robert McKinlay , Chi-En Lin , Tri T. Dang
Abstract: An analyte biosensor is provided having an analyte biosensing layer and an ethylene oxide absorption layer. The ethylene oxide absorption layer is provided over the analyte biosensing layer. A method is also provided.
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公开(公告)号：US20210077717A1
公开(公告)日：2021-03-18
申请号：US16569401
申请日：2019-09-12
Applicant: MEDTRONIC MINIMED, INC.
Inventor： Akhil Srinivasan , Peter Ajemba , Steven C. Jacks , Robert C. Mucic , Tyler R. Wong , Melissa Tsang , Chi-En Lin , Mohsen Askarinya , David Probst
IPC: A61M5/172 , A61B5/145 , A61M5/142 , A61B5/1495
Abstract: Medical devices and related systems and methods are provided. A method of calibrating an instance of a sensing element involves obtaining fabrication process measurement data from a substrate having the instance of the sensing element fabricated thereon, obtaining a calibration model associated with the sensing element, determining calibration data associated with the instance of the sensing element for converting the electrical signals into a calibrated measurement parameter based on the fabrication process measurement data using the calibration model, and storing the calibration data in a data storage element associated with the instance of the sensing element.
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4.发明申请公开(公告)号：US20200315504A1
公开(公告)日：2020-10-08
申请号：US16375752
申请日：2019-04-04
Applicant: MEDTRONIC MINIMED, INC.
Inventor： Chi-En Lin , David Probst , Mohsen Askarinya , Akhil Srinivasan , Melissa Tsang , Michael E. Miller , Parisa Kamgar
IPC: A61B5/145 , A61B5/1486 , C12Q1/54 , G01N27/327 , A61B5/00
Abstract: The invention includes method and materials designed to measure the material properties (e.g. thickness) of layers of material in a sensor using non-Faradaic EIS (Electrochemical Impedance Spectroscopy) methods. The methods are non-destructive, very sensitive and rapid. Typically in these methods, an AC voltage is applied to the desired material layer while the output current and therefore impedance is measured. This voltage can be applied in multiple frequencies in sweep mode in order to detect both the material and, for example, the thickness of the target material. In this way, EIS allows the characterization of properties of various layers of material disposed in devices such as electrochemical glucose sensors.
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公开(公告)号：US20240060111A1
公开(公告)日：2024-02-22
申请号：US18500708
申请日：2023-11-02
Applicant: Medtronic MiniMed, Inc.
Inventor： Robert McKinlay , Chi-En Lin , Tri T. Dang
Abstract: An analyte biosensor is provided having an analyte biosensing layer and an ethylene oxide absorption layer. The ethylene oxide absorption layer is provided over the analyte biosensing layer. A method is also provided.
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Patent Agency Ranking
公开(公告)号：US11821022B2
公开(公告)日：2023-11-21
申请号：US16725957
申请日：2019-12-23
Applicant: Medtronic MiniMed, Inc.
Inventor： Robert McKinlay , Chi-En Lin , Tri T. Dang
Abstract: An analyte biosensor is provided having an analyte biosensing layer and an ethylene oxide absorption layer. The ethylene oxide absorption layer is provided over the analyte biosensing layer. A method is also provided.
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公开(公告)号：US20230241315A1
公开(公告)日：2023-08-03
申请号：US18132321
申请日：2023-04-07
Applicant: MEDTRONIC MINIMED, INC.
Inventor： Akhil Srinivasan , Peter Ajemba , Steven C. Jacks , Robert C. Mucic , Tyler R. Wong , Melissa Tsang , Chi-En Lin , Mohsen Askarinya , David Probst
IPC: A61M5/172 , A61B5/145 , A61M5/142 , A61B5/1495
CPC classification number: A61M5/1723 , A61B5/14532 , A61M5/14244 , A61B5/1495 , A61B5/4839
Abstract: Medical devices and related systems and methods are provided. A method of controlling medication delivery based on sensor input involves obtaining a measurement parameter representing an electrical response of a first instance of a sensing element to a physiological condition of a person. The measurement parameter is converted into a calibrated measurement parameter using calibration data specific to the first instance of the sensing element. The method further involves determining a measurement value using the calibrated measurement parameter as input to a performance model. The performance model is derived from historical calibrated measurement parameters and corresponding reference values. The historical calibrated measurement parameters are from other instances of the sensing element. A command is then determined based on the measurement value and sent to a medical device. The command causes the medical device to deliver a dose of medication influencing the physiological condition of the person.
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公开(公告)号：US20230172497A1
公开(公告)日：2023-06-08
申请号：US17980018
申请日：2022-11-03
Applicant: Medtronic MiniMed, Inc.
Inventor： Jenn-Hann L. Wang , Anna J. Miller , Chi-En Lin , Melissa Tsang , Akhil Srinivasan , Quyen B. Ong
IPC: A61B5/145 , C12Q1/00 , A61B5/1486
CPC classification number: A61B5/14546 , C12Q1/005 , A61B5/1486
Abstract: The invention provides amperometric analyte sensor systems comprising one or more electrodes designed to monitor in vivo levels of 3-hydroxybutyrate (and optionally glucose as well) in order to facilitate the management of diabetic ketoacidosis. The invention further includes dual layer membrane compositions, elements and methods useful with such amperometric analyte sensor systems.
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公开(公告)号：US20220338768A1
公开(公告)日：2022-10-27
申请号：US17226412
申请日：2021-04-09
Applicant: Medtronic MiniMed, Inc.
Inventor： Melissa Tsang , Michael N. Missaghi , Anna Miller , Chi-En Lin , Mohsen Askarinya , Akhil Srinivasan , Nicole Abraham
IPC: A61B5/1486 , A61B5/145 , B05D1/00
Abstract: Embodiments of the invention provide methods and materials for making analyte sensors having a plurality of layered elements such as amperometric glucose sensors that are used by diabetic individuals to monitor blood sugar concentrations. Embodiments of the invention utilize plasma deposition technologies to form thin films of hexamethyldisiloxane useful in such sensors. Sensors that incorporate the thin film compositions formed by these processes exhibit a number of desirable characteristics.
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10.发明授权公开(公告)号：US11311215B2
公开(公告)日：2022-04-26
申请号：US16375752
申请日：2019-04-04
Applicant: MEDTRONIC MINIMED, INC.
Inventor： Chi-En Lin , David Probst , Mohsen Askarinya , Akhil Srinivasan , Melissa Tsang , Michael E. Miller , Parisa Kamgar
IPC: A61B5/145 , A61B5/1486 , G01N27/327 , C12Q1/54 , G01N27/02 , A61B5/00 , C12Q1/00
Abstract: The invention includes method and materials designed to measure the material properties (e.g. thickness) of layers of material in a sensor using non-Faradaic EIS (Electrochemical Impedance Spectroscopy) methods. The methods are non-destructive, very sensitive and rapid. Typically in these methods, an AC voltage is applied to the desired material layer while the output current and therefore impedance is measured. This voltage can be applied in multiple frequencies in sweep mode in order to detect both the material and, for example, the thickness of the target material. In this way, EIS allows the characterization of properties of various layers of material disposed in devices such as electrochemical glucose sensors.
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