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1.发明授权公开(公告)号：US06913933B2
公开(公告)日：2005-07-05
申请号：US10005257
申请日：2001-12-03
IPC分类号： G01F11/16 , B01L99/00 , B67D7/02 , F04B7/06 , F04B9/02 , F04B13/00 , F04B49/06 , G01N35/10 , G05D7/06 , G01N1/10 , G01N15/06 , G01N21/00 , G01N35/00 , G01N35/08
CPC分类号： B01L3/0289 , B01L2200/0615 , B01L2400/0487 , F04B7/06 , F04B13/00 , G01N35/1016 , G01N2035/102 , G05D7/0676 , Y10T436/11 , Y10T436/119163 , Y10T436/2575
摘要： A method for improving the fluid dispense rate in a metering system utilizing speed includes the steps of modifying the fluid flow rate profile during a portion thereof so as substantially increase or decrease the speed of the motor during certain portions of a metering cycle in order to improve the efficiency of the metering system. For a variable speed pump producing a sinusoidal speed profile, the pump motor speed can be increased to increase the dispense velocity during the beginning and end of the dispense phase to reduce perfusion and improve metered volume precision or a motor speed profile can be applied which is inverted relative to that of the variable speed pump to produce a constant velocity flow. Alternately or in addition to the above, the home position of the variable speed pump can be shifted to produce fluid velocity during the entirety of a dispense portion of a metering system cycle.
摘要翻译： 用于改善计量系统利用速度的流体分配速率的方法包括以下步骤：在其一部分期间改变流体流速分布，以便在计量循环的某些部分期间大幅度地增加或减少电动机的速度，以改善 计量系统的效率。 对于产生正弦速度曲线的变速泵，可以增加泵电机速度，以在分配阶段的开始和结束期间增加分配速度，以减少灌注并提高计量体积精度或可应用电机速度分布 相对于变速泵的转速产生恒定的速度流。 或者除了上述之外，可以移动变速泵的原始位置以在计量系统循环的整个分配部分的整体期间产生流体速度。
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公开(公告)号：US09719906B2
公开(公告)日：2017-08-01
申请号：US13366876
申请日：2012-02-06
CPC分类号： G01N15/042 , G01N15/05 , G01N33/491 , G01N35/1009 , G01N2015/055
摘要： A method for determining a condition in a blood sample includes: providing a sample of blood; providing a metering probe having a pump for aspirating and dispensing; inserting the metering probe a selected distance into the blood sample; measuring the pressure between the sample and pump during sample aspiration or sample dispense; comparing the measured pressure with a reference value; and signaling the presence or absence of the condition. A method for confirming or detecting the presence of a selected layer of blood component in a centrifuged blood sample includes: measuring a pressure of a suspected selected layer in a metering probe during aspiration or dispense; comparing the measured pressure with a reference value, wherein if the measured pressure and the reference value are substantially identical then the selected layer of the blood component is confirmed. In a preferred embodiment the reference value is a pre-selected pressure range.
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公开(公告)号：US09574985B2
公开(公告)日：2017-02-21
申请号：US13366876
申请日：2012-02-06
摘要： A method for determining a condition in a blood sample includes: providing a sample of blood; providing a metering probe having a pump for aspirating and dispensing; inserting the metering probe a selected distance into the blood sample; measuring the pressure between the sample and pump during sample aspiration or sample dispense; comparing the measured pressure with a reference value; and signaling the presence or absence of the condition. A method for confirming or detecting the presence of a selected layer of blood component in a centrifuged blood sample includes: measuring a pressure of a suspected selected layer in a metering probe during aspiration or dispense; comparing the measured pressure with a reference value, wherein if the measured pressure and the reference value are substantially identical then the selected layer of the blood component is confirmed. In a preferred embodiment the reference value is a pre-selected pressure range.
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公开(公告)号：US20120202238A1
公开(公告)日：2012-08-09
申请号：US13366876
申请日：2012-02-06
IPC分类号： C12Q1/02
CPC分类号： G01N15/042 , G01N15/05 , G01N33/491 , G01N35/1009 , G01N2015/055
摘要： A method for determining a condition in a blood sample includes: providing a sample of blood; providing a metering probe having a pump for aspirating and dispensing; inserting the metering probe a selected distance into the blood sample; measuring the pressure between the sample and pump during sample aspiration or sample dispense; comparing the measured pressure with a reference value; and signaling the presence or absence of the condition. A method for confirming or detecting the presence of a selected layer of blood component in a centrifuged blood sample includes: measuring a pressure of a suspected selected layer in a metering probe during aspiration or dispense; comparing the measured pressure with a reference value, wherein if the measured pressure and the reference value are substantially identical then the selected layer of the blood component is confirmed. In a preferred embodiment the reference value is a pre-selected pressure range.
摘要翻译： 用于确定血液样品中的状况的方法包括：提供血液样品; 提供具有用于抽吸和分配的泵的计量探针; 将测量探针插入血液样本中的选定距离; 在样品抽吸或样品分配期间测量样品和泵之间的压力; 将测量的压力与参考值进行比较; 并发出状况的存在或不存在。 用于确认或检测离心血液样品中所选择的血液成分层的存在的方法包括：在抽吸或分配期间测量计量探针中的疑似选择的层的压力; 将测量的压力与参考值进行比较，其中如果测量的压力和参考值基本相同，则确认所选择的血液成分层。 在优选实施例中，参考值是预选压力范围。
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公开(公告)号：US07361509B2
公开(公告)日：2008-04-22
申请号：US10134409
申请日：2002-04-29
申请人： David D. Hyde , Joseph S. Douglas
发明人： David D. Hyde , Joseph S. Douglas
CPC分类号： G01N35/1016 , G01N2035/0475 , G01N2035/1025 , Y10T436/11 , Y10T436/112499 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： A method for dynamically determining the volume of a liquid dispensed by a metering system, the metering system including a metering pump, a pump motor, a sensor, and a conduit interconnecting the pump and a metering probe. The method includes the steps of aspirating a quantity of fluid into the metering probe using the metering pump, moving the probe relative to a reaction vessel, and dispensing the fluid. The dispensing step includes the steps of identifying an onset point associated with a parameter which can be measured by the metering system, identifying an end point associated with the measurable parameter, and timing the pump motor during the period between the onset point and the end point in order to determine fluid volume. The sensor, such as a pressure transducer or capacitance change sensor, disposed in relation to the conduit can detect changes in the parameter and identify the onset and end points.
摘要翻译： 一种用于动态地确定由计量系统分配的液体的体积的方法，所述计量系统包括计量泵，泵马达，传感器以及将所述泵和计量探针互连的导管。 该方法包括以下步骤：使用计量泵将一定量的流体吸入测量探针中，相对于反应容器移动探针并分配流体。 分配步骤包括以下步骤：识别与可以由计量系统测量的参数相关联的起始点，识别与可测量参数相关联的终点，以及在起始点和终点之间的时间段内定时泵马达 以确定流体体积。 相对于管道设置的传感器，例如压力传感器或电容变化传感器，可以检测参数的变化并识别出发点和终点。
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公开(公告)号：US07926344B1
公开(公告)日：2011-04-19
申请号：US11959537
申请日：2007-12-19
申请人： David D. Hyde , John A. Reyner
发明人： David D. Hyde , John A. Reyner
IPC分类号： G01F23/296
CPC分类号： G01F23/2968
摘要： An ultrasonic, non-invasive, bottom-up fluid level sensor for a container, includes: an ultrasonic transducer; and a dry couplant in acoustic communication with the transducer. The dry couplant is configured to adapt to the bottom surface of the container and the sensor contains nothing to bias the sensor against the container other than the weight of the container and fluid.
摘要翻译： 一种用于容器的超声波，非侵入性，自下而上的液位传感器，包括：超声换能器; 以及与换能器声学连通的干燥耦合剂。 干燥的耦合剂被配置成适应容器的底部表面，并且除了容器和流体的重量之外，传感器不含任何物体以将传感器偏压在容器之外。
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7.发明授权Low-cost runout sensor with high frequency response and negligible stiction in the direction of travel 失效低成本的跳动传感器具有高频率响应，并且在行驶方向上可以忽略不计
公开(公告)号：US5610329A
公开(公告)日：1997-03-11
申请号：US402433
申请日：1995-03-10
申请人： Albert J. Yovichin , William F. Dunn , William R. Dutt , Richard C. Houck , David D. Hyde , Raouf A. Ridha , Harry R. Swanson
发明人： Albert J. Yovichin , William F. Dunn , William R. Dutt , Richard C. Houck , David D. Hyde , Raouf A. Ridha , Harry R. Swanson
摘要： An apparatus which uses a sensing device for measuring gauges of elastomeric or rigid articles, or runout of elastomeric articles, has a pivoting arm which holds a means for creating a signal, and is movable relative to the object being measured. The means for creating a signal provides a signal to the sensing device, and the magnitude of the signal depends on the position of the pivoting arm relative to the object being measured. Movement of the pivoting arm, caused by changes in the dimensions of the object, can be recorded and analyzed.
摘要翻译： 使用用于测量弹性体或刚性制品的量度的传感装置或弹性制品的跳动的装置具有枢转臂，其保持用于产生信号的装置，并且可相对于被测量物体移动。 用于产生信号的装置向感测装置提供信号，并且信号的大小取决于枢转臂相对于被测量物体的位置。 可以记录和分析由对象的尺寸变化引起的枢转臂的移动。
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公开(公告)号：US4615866A
公开(公告)日：1986-10-07
申请号：US635295
申请日：1984-07-27
申请人： David D. Hyde , James R. Stuart
发明人： David D. Hyde , James R. Stuart
CPC分类号： G01N35/025 , G01N2035/1025 , Y10T436/11
摘要： Fluid-sampling system and method for automated, chemistry-analyzing apparatus for withdrawing precise quantities of serum samples from a specimen container and for dispensing the samples into reagent containers for analysis. The apparatus includes a sampler assembly coupled to pressure-generating means for the withdrawal and dispensing of the serum by the sampler assembly. The system is designed such that the quantity of a serum sample taken up and dispensed will be a function only of the fluid mechanics of the sampling system and the timed operation of a control valve rather than being a function of any pressure variations established in the flow control means as in prior systems. This permits infinitely variable, very small, yet very precise quantities of a serum or other fluid to be taken up and dispensed permitting more efficient and cost effective use of available serum. The apparatus further includes means for simultaneously withdrawing more than one sample of a particular serum from a serum specimen container for permitting more than one test to be initiated on a particular serum during a single cycle of the chemistry-analyzing apparatus. Serum-level detecting means are also provided to ensure that the sampler assembly is properly immersed in a serum specimen before the pressure-generating means is actuated to withdraw serum therefrom. A microprocessor controller is provided to control the overall operation of the fluid-sampling system.
摘要翻译： 用于自动化学分析装置的流体取样系统和方法，用于从样本容器中取出精确量的血清样品，并将样品分配到试剂容器中进行分析。 该装置包括一个连接到压力产生装置的取样器组件，用于通过取样器组件取出和分配血清。 该系统被设计成使得采集和分配的血清样品的量将仅仅是采样系统的流体力学和控制阀的定时操作的功能，而不是在流动中建立的任何压力变化的函数 如现有系统中的控制装置。 这允许无限变化，非常小，但非常精确的量的血清或其他流体被摄取和分配，从而允许更有效和成本有效地使用可用的血清。 该装置还包括用于从血清样本容器同时抽出多于一个特定血清样品的装置，用于允许在化学分析装置的单个循环期间在特定血清上启动多于一个的测试。 还提供了血清水平检测装置，以确保采样器组件在致动压力发生装置之前被适当地浸入血清样本中以从其中抽出血清。 提供微处理器控制器以控制流体采样系统的整体操作。
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