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41 条记录 (耗时 0.054 秒)

    Monitoring method
    1.
    发明授权
    Monitoring method 失效
    监测方法

    公开(公告)号：US5467778A

    公开(公告)日：1995-11-21

    申请号：US109503

    申请日：1993-08-20

    申请人： Michael Catt ,  John Coley ,  Paul J. Davis

    发明人： Michael Catt ,  John Coley ,  Paul J. Davis

    IPC分类号： G01N33/493 ,  A61B10/00 ,  G01N20060101 ,  G01N33/50 ,  G01N33/52 ,  G01N33/68 ,  G01N33/74 ,  G01N33/76

    CPC分类号： G01N33/689 ,  A61B10/0012 ,  G01N33/743 ,  G01N33/76 ,  G01N2800/36

    摘要： A method of monitoring the status of a current ovulation cycle of an individual human female subject, involving testing of the body fluid concentration of an analyte of significance in relation to the status of the ovulation cycle, such as urinary E3G, during at least part of the pre-ovulation phase of the current ovulation cycle of the individual subject, and identification from the results of such testing an analyte concentration change indicative of imminent ovulation, relative to an analyte concentration reference value that has been adapted to the individual human subject on the basis of analyte concentration test data obtained from the individual human subject during one or more previous ovulation cycles. Preferably testing for said analyte concentration during the current ovulation cycle is commenced a plurality of days (preferably at least 5) following the onset of menses but at least 2 numerical days in advance of the earliest numerical day on which actual ovulation has occurred in one or more previous ovulation cycles in the same individual subject.

    摘要翻译： 一种监测个体人类女性受试者当前排卵周期状态的方法，包括在至少部分时间内测量相对于排卵周期状态（例如尿E3G）的有意义的分析物的体液浓度 个体受试者当前排卵周期的排卵前阶段以及相对于已经适应于个体受试者的分析物浓度参考值的来自这种测试结果的指示即将排卵的分析物浓度变化的鉴定 在一个或多个以前的排卵周期中从个体人受试者获得的分析物浓度测试数据的基础。 优选地，在当前排卵周期期间对所述分析物浓度的测试在月经开始之后开始多天（优选至少5天），但是在实际排卵发生在一个或多个之前的最早数字日之前的至少2个数天 在同一个体科目中更多的排卵周期。

    Processes and apparatus for carrying out specific binding assays
    4.
    发明授权
    Processes and apparatus for carrying out specific binding assays 失效
    用于进行特异性结合测定的方法和设备

    公开(公告)号：US5610077A

    公开(公告)日：1997-03-11

    申请号：US275755

    申请日：1994-07-19

    申请人： Paul J. Davis ,  Philip Porter

    发明人： Paul J. Davis ,  Philip Porter

    IPC分类号： G01N33/543 ,  G01N33/577 ,  G01N33/53

    CPC分类号： G01N33/54393 ,  G01N33/54366 ,  G01N33/577 ,  Y10S435/81 ,  Y10S435/962 ,  Y10S436/807 ,  Y10S436/809 ,  Y10S436/81

    摘要： A process for carrying out a specific binding assay by reacting (a) a sample under assay for the possible presence of a substance being tested for, (b) a specific binding partner for the substance being tested for, immobilised on a solid support, and (c) a specific binding partner for the substance being tested for which is conjugated to a detectable marker, to thereby form a complex by reacting between whatever quantities are present of the substance being tested for in (a) with reagents (b) and (c). The marker is immobilised to the support via the substance being tested for, and is detected or assayed as an index of the quantity present in the sample (a) of any of the substance. The reaction ingredients (a), (b) and (c) are all mixed in a single step for reaction in a single reaction liquid. Competitive interference between the binding reactions of the substance being tested for and reagents (b) and (c) is avoided by use of monoclonal antibodies of narrow and different, non-interfering specificity, reaction reagent (b) is immobilized on the surface of a displacer body.

    摘要翻译： 通过使（a）测定中的样品与被测试物质可能存在的（a）待测物质的特异性结合配偶体固定在固体支持物上，进行特异性结合测定的方法，以及 （c）所测试物质的特异性结合配偶体与可检测标记物缀合，从而通过在（a）中被测物质中存在的任何量与试剂（b）和（ C）。 标记物经被测试的物质固定在载体上，并被检测或测定为任何物质的样品（a）中存在的量的指标。 反应成分（a），（b）和（c）都在单一步骤中混合，以便在单一反应液体中反应。 被测物质与试剂（b）和（c）的结合反应之间的竞争性干扰通过使用窄而不同的非干扰特异性的单克隆抗体来避免，反应试剂（b）固定在 置换器体。

    Method for the control of coccidiosis in poultry
    5.
    发明授权
    Method for the control of coccidiosis in poultry 失效
    控制家禽球虫病的方法

    公开(公告)号：US4544548A

    公开(公告)日：1985-10-01

    申请号：US487593

    申请日：1983-04-27

    申请人： Paul J. Davis ,  James F. Reynolds

    发明人： Paul J. Davis ,  James F. Reynolds

    IPC分类号： A23K1/00 ,  A61K35/68 ,  A61K39/012 ,  A61K37/00

    CPC分类号： A61K39/012 ,  A23K10/18 ,  A61K35/68

    摘要： Effective immunity against coccidiosis can be imparted to poultry if the birds are reared on a regular diet containing added viable sporulated coccidia oocysts at a level sufficient only to induce sub-clinical infection. Preferably the oocyst-containing diet is presented to the birds as soon as they are able to ingest solid food, and contains from 10 to 10,000 oocysts per kg of nutrient feed material. The simultaneous administration of an anti-coccidial drug at a curative level can help to control the immunity-producing infection. The oocyst-containing feedstuff of the invention can be prepared using solid free-flowing pre-mixes or aqueous concentrates, containing appropriate numbers of oocysts together with edible thickening agents. The oocysts can be protected against loss of viability through dehydration by being encapsulated. Growth of the immunized birds is sustained even when they are exposed to a severe oocyst challenge sufficient to induce serious infection in unimmunized birds.

    摘要翻译： 如果鸟类以常规饮食饲养，包括添加有活性球孢子虫卵囊的水平足以诱发亚临床感染，则可以对禽类赋予有效的抗球虫病免疫力。 优选地，含有卵囊的饮食一旦能够摄入固体食物就呈现给鸟类，并且每kg营养饲料含有10至10,000个卵囊。 以治疗水平同时施用抗球虫药可以帮助控制产生免疫力的感染。 本发明的含有卵囊的饲料可以使用含有适量数量的卵囊和可食用增稠剂的固体自由流动的预混合物或含水浓缩物制备。 可以通过包封来防止卵囊的脱水丧失。 即使暴露于足以在未免疫的鸟类中诱发严重感染的严重的卵囊攻击，免疫的鸟类的生长仍然持续。