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公开(公告)号：US6159949A
公开(公告)日：2000-12-12
申请号：US7476
申请日：1998-01-15
申请人： Michael Terence Black , Deborah Dee Jaworski , Anna Lisa Kosmatka , Christopher Michael Traini , Richard Warren , Min Wang
发明人： Michael Terence Black , Deborah Dee Jaworski , Anna Lisa Kosmatka , Christopher Michael Traini , Richard Warren , Min Wang
IPC分类号： C12N15/09 , A61K31/00 , A61K38/00 , A61K39/085 , A61K39/395 , A61K45/00 , A61K48/00 , A61P31/00 , C07K14/195 , C07K14/31 , C07K16/14 , C12N1/21 , C12N15/00 , C12N15/31 , C12P21/02 , C12P21/08 , C12R1/445 , G01N33/53 , G01N33/566 , C07H21/00 , C12N15/63
摘要： The invention provides ftsY polypeptides and polynucleotides encoding ftsY polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ftsY polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供了编码ftsY多肽的ftsY多肽和多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用ftsY多肽筛选抗菌化合物的方法。
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公开(公告)号：US6072032A
公开(公告)日：2000-06-06
申请号：US7484
申请日：1998-01-15
申请人： Michael Terence Black , Deborah Dee Jaworski , Anna Lisa Kosmatka , Christopher Michael Traini , Min Wang , Richard Lloyd Warren, Jr.
发明人： Michael Terence Black , Deborah Dee Jaworski , Anna Lisa Kosmatka , Christopher Michael Traini , Min Wang , Richard Lloyd Warren, Jr.
IPC分类号： G01N33/50 , A61K31/00 , A61K38/00 , A61K39/09 , A61K39/395 , A61K45/00 , A61K48/00 , A61P11/00 , A61P25/00 , A61P27/00 , A61P27/02 , A61P27/16 , A61P29/00 , A61P31/00 , A61P31/04 , C07K14/315 , C07K14/705 , C07K16/28 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/00 , C12N15/09 , C12N15/31 , C12P21/02 , C12Q1/02 , C12R1/46 , G01N33/15 , G01N33/566 , G01N33/569 , G01N33/68 , C07K1/00
CPC分类号： C07K14/3156 , G01N33/56944 , A61K38/00
摘要： The invention provides ftsY polypeptides and polynucleotides encoding ftsY polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ftsY polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供了编码ftsY多肽的ftsY多肽和多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用ftsY多肽筛选抗菌化合物的方法。
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公开(公告)号：US06284878B1
公开(公告)日：2001-09-04
申请号：US08991023
申请日：1997-12-15
申请人： Michael Arthur Lonetto , Deborah Dee Jaworski , Min Wang , Richard Lloyd Warren , Christopher Michael Traini , Anna Lisa Kosmatka , David Justin Charles Knowles , John Edward Hodgson , Michael Terence Black , David J. Holmes , Richard Oakley Nicholas , Robert King Stodola
发明人： Michael Arthur Lonetto , Deborah Dee Jaworski , Min Wang , Richard Lloyd Warren , Christopher Michael Traini , Anna Lisa Kosmatka , David Justin Charles Knowles , John Edward Hodgson , Michael Terence Black , David J. Holmes , Richard Oakley Nicholas , Robert King Stodola
IPC分类号： C07H2102
CPC分类号： C12N9/1205 , A61K38/00 , A61K39/00 , C07K14/3156 , C12N9/78 , C12N9/80 , C12Y207/01002
摘要： The invention provides def1 polypeptides and polynucleotides encoding def1 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing def1 polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供了def1多肽和编码def1多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用def1多肽筛选抗菌化合物的方法。
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公开(公告)号：US06214348B1
公开(公告)日：2001-04-10
申请号：US09309682
申请日：1999-05-11
申请人： Michael Terence Black , Deborah Dee Jaworski , Min Wang , Christopher Michael Traini , Anna Lisa Kosmatka , Richard Lloyd Warren, Jr.
发明人： Michael Terence Black , Deborah Dee Jaworski , Min Wang , Christopher Michael Traini , Anna Lisa Kosmatka , Richard Lloyd Warren, Jr.
IPC分类号： A61K3902
CPC分类号： C07K14/3156 , A61K38/00 , G01N33/56944
摘要： The invention provides ftsY polypeptides and polynucleotides encoding ftsY polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ftsY polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供了编码ftsY多肽的ftsY多肽和多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用ftsY多肽筛选抗菌化合物的方法。
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5.发明授权Phospho-N-acetylmuramoyl-pentapeptide transferase of Streptococcus pneumoniae 失效肺炎链球菌的磷酸-N-乙酰基胞壁酰胺 - 五肽转移酶
公开(公告)号：US6156537A
公开(公告)日：2000-12-05
申请号：US61156
申请日：1998-04-16
申请人： Joanna Lynn Fueyo , Deborah Dee Jaworski , Anna Lisa Kosmatka , Michael Arthur Lonetto , Christopher Michael Traini , Min Wang
发明人： Joanna Lynn Fueyo , Deborah Dee Jaworski , Anna Lisa Kosmatka , Michael Arthur Lonetto , Christopher Michael Traini , Min Wang
IPC分类号： G01N33/15 , A61K31/70 , A61K31/7088 , A61K38/00 , A61K38/45 , A61K38/55 , A61K39/395 , A61K48/00 , C07K14/315 , C07K16/12 , C12N1/21 , C12N9/10 , C12N15/09 , C12N15/31 , C12N15/54 , C12P21/02 , C12Q1/68 , C12N15/52 , C12N15/62 , C12N15/63
摘要： The invention provides mraY polypeptides and polynucleotides encoding mraY polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing mraY polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供了mraY多肽和编码mraY多肽的多核苷酸以及通过重组技术产生这种多肽的方法。 还提供了利用mraY多肽筛选抗菌化合物的方法。
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公开(公告)号：US06660520B2
公开(公告)日：2003-12-09
申请号：US09092218
申请日：1998-06-05
申请人： Michael Terence Black , Deborah Dee Jaworski , Anna Lisa Kosmatka , Lisa Kathleen Shilling , Min Wang , Edwina Imogen Wilding
发明人： Michael Terence Black , Deborah Dee Jaworski , Anna Lisa Kosmatka , Lisa Kathleen Shilling , Min Wang , Edwina Imogen Wilding
IPC分类号： C12N1500
CPC分类号： G01N33/5091 , A61K38/00 , C07K14/3156 , G01N33/5008 , G01N33/502 , G01N33/573 , G01N33/6872
摘要： The invention provides nrdE polypeptides and polynucleotides encoding nrdE polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing nrdE polypeptides to screen for antibacterial compounds.
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公开(公告)号：US06335424B1
公开(公告)日：2002-01-01
申请号：US08979616
申请日：1997-11-25
申请人： Michael Terence Black , Christine Debouck , Jason Craig Fedon , John Edward Hodgson , Deborah Dee Jaworski , David Justin Charles Knowles , Anna Lisa Kosmatka , Jeffrey Mooney , Richard Oakley Nicholas , Leslie Marie Palmer , Lisa Kathleen Shilling , Robert King Stodola , Min Wang , Richard Lloyd Warren , Yi Yi Zhong
发明人： Michael Terence Black , Christine Debouck , Jason Craig Fedon , John Edward Hodgson , Deborah Dee Jaworski , David Justin Charles Knowles , Anna Lisa Kosmatka , Jeffrey Mooney , Richard Oakley Nicholas , Leslie Marie Palmer , Lisa Kathleen Shilling , Robert King Stodola , Min Wang , Richard Lloyd Warren , Yi Yi Zhong
IPC分类号： A61K3902
CPC分类号： C07K14/3156 , A61K38/00 , A61K39/00 , C12N9/1205 , C12N9/78 , C12N9/80 , C12N9/90 , C12N15/52 , C12Y207/01002
摘要： The invention provides ribG polypeptides and polynucleotides encoding ribG polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribG polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供ribG多肽和编码ribG多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用ribG多肽筛选抗菌化合物的方法。
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8.发明授权公开(公告)号：US06190881B1
公开(公告)日：2001-02-20
申请号：US09092437
申请日：1998-06-05
申请人： Michael Terence Black , Deborah Dee Jaworski , Anna Lisa Kosmatka , Lisa Kathleen Shilling , Min Wang , Edwina Imogen Wilding
发明人： Michael Terence Black , Deborah Dee Jaworski , Anna Lisa Kosmatka , Lisa Kathleen Shilling , Min Wang , Edwina Imogen Wilding
IPC分类号： C07H2100
CPC分类号： C12N9/0093 , A61K38/00 , C12Y117/04001
摘要： The invention provides nrdF polypeptides and polynucleotides encoding nrdF polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing nrdF polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供nrdF多肽和编码nrdF多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用nrdF多肽筛选抗菌化合物的方法。
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公开(公告)号：US06346395B1
公开(公告)日：2002-02-12
申请号：US09239052
申请日：1999-01-27
申请人： Alison Francis Chalker , Christine Debouck , David John Holmes , Karen Anne Ingraham , Deborah Dee Jaworski , Anna Lisa Kosmatka , Damien McDevitt , Jeffrey Mooney , Stewart C Pearson , Chi Yong So , Nicola Gail Wallis , Min Wang , Richard Lloyd Warren , Yi Yi Zhong
发明人： Alison Francis Chalker , Christine Debouck , David John Holmes , Karen Anne Ingraham , Deborah Dee Jaworski , Anna Lisa Kosmatka , Damien McDevitt , Jeffrey Mooney , Stewart C Pearson , Chi Yong So , Nicola Gail Wallis , Min Wang , Richard Lloyd Warren , Yi Yi Zhong
IPC分类号： C12D2106
CPC分类号： C12N9/0006 , A61K38/00 , C12Y101/011
摘要： The invention provides FabG polypeptides and polynucleotides encoding FabG polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing FabG polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供了FabG多肽和编码FabG多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用FabG多肽筛选抗菌化合物的方法。
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公开(公告)号：US06270992B1
公开(公告)日：2001-08-07
申请号：US08963901
申请日：1997-11-04
申请人： Nicola Gail Wallis , Christopher Michael Traini , Anna Lisa Kosmatka , Lisa Kathleen Shilling , Richard Lloyd Warren
发明人： Nicola Gail Wallis , Christopher Michael Traini , Anna Lisa Kosmatka , Lisa Kathleen Shilling , Richard Lloyd Warren
IPC分类号： C12N500
CPC分类号： C12N9/1223 , A61K39/00 , A61K2039/51
摘要： The invention provides Histidine kinase polypeptides and polynucleotides encoding Histidine kinase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Histidine kinase polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供组氨酸激酶多肽和编码组氨酸激酶多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用组氨酸激酶多肽筛选抗菌化合物的方法。
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