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1.发明申请Fluid Bag, Use of One or More Fluid Bags, and a System Including One or More Fluid Bags 审中-公开流体袋，一个或多个流体袋的使用以及包括一个或多个流体袋的系统公开(公告)号：US20070265594A1
公开(公告)日：2007-11-15
申请号：US10588963
申请日：2005-02-10
IPC分类号： A61J1/10
CPC分类号： A61J1/2093 , A61J1/10 , A61J1/14 , A61J1/2024 , A61J1/2027 , A61M1/1656 , A61M1/1668 , A61M1/167 , A61M1/287 , A61M1/3455 , A61M1/3465 , A61M2209/082
摘要： The invention concerns a fluid bag that contains either dialysis fluid for hemodialysis or a replacement fluid for replacing ultra-filtrate that is withdrawn from a patient or a fluid that is a rest product from a process of hemodialysis or the like. The fluid bag has a first main sheet and a second main sheet located opposite to the first main sheet. The fluid bag is sized to contain at least a certain quantity (q) of fluid, measured in ml, when it is completely filled with fluid. The fluid bag is configured so that the distance between the first and second sheets never exceeds a certain value (v), measured in mm, wherein: q≧2000, and v≦2q/100. The invention also concerns a fluid bag assembly including one or more such fluid bags as well as a system including one or more such fluid bags.
摘要翻译： 本发明涉及一种流体袋，其包含用于血液透析的透析液或用于替换从患者抽出的超滤液的替代液体或者是来自血液透析过程等的静止产物的流体。 流体袋具有与第一主片相对的第一主片和第二主片。 当流体袋完全充满流体时，流体袋的尺寸至少包含一定量的（q）流体，以ml计。 流体袋被配置成使得第一和第二片之间的距离不会超过以mm测量的特定值（v），其中：q> = 2000，v <= 2q / 100。 本发明还涉及包括一个或多个这种流体袋的流体袋组件以及包括一个或多个这种流体袋的系统。
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2.发明授权Method and device for detecting the detachment of the venous needle from a patient during dialysis 有权用于在透析期间检测静脉针从患者脱离的方法和装置公开(公告)号：US07648474B2
公开(公告)日：2010-01-19
申请号：US10481955
申请日：2002-06-24
CPC分类号： A61M1/3639 , A61M1/3653 , A61M1/3656 , A61M1/367 , A61M5/16831 , A61M2039/1005 , A61M2205/13 , A61M2205/3331
摘要： A method of detecting the detachment of the venous needle from a patient during an extracorporeal blood treatment in a dialysis machine having an extracorporeal blood circuit provided with an arterial branch and a venous branch. The arterial pressure (Pa) is measured in the arterial branch and the venous pressure (Pv) is measured in the venous branch, and the determination is made of whether or not decreases of the arterial pressures (Pa) and venous pressures (Pv) are occurring during the dialysis treatment in normal conditions.
摘要翻译： 在具有动脉分支和静脉分支的体外血液回路的透析机中检测静脉针在体外血液处理期间脱离的方法。 在动脉分支中测量动脉压（Pa），并在静脉分支中测量静脉压（Pv），并且确定动脉压（Pa）和静脉压（Pv）的降低是否为 在正常情况下透析治疗期间发生。
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公开(公告)号：US07131956B1
公开(公告)日：2006-11-07
申请号：US09787624
申请日：2000-07-28
CPC分类号： A61M1/16 , A61M1/1601 , A61M1/1647 , A61M1/3403 , A61M1/3434 , A61M1/3437 , A61M1/3441 , A61M1/361 , A61M1/3639 , A61M2205/18 , A61M2205/3331 , A61M2205/3334 , A61M2205/50 , A61M2205/702 , A61M2205/707 , A61M2205/7563 , A61M2230/207
摘要： A dialysis machine comprises: means for calculating (60) a filtration factor (FF) as a function of the ultrafiltration rate (UFR) and of a plasma flow rate (Qp); first comparison means (65) for comparing the filtration factor (FF) with a limit value of admissibility; and signaling means (70) for generating a signal (A) indicating the result of the comparison.
摘要翻译： 一种透析机包括：用于根据超滤速率（UFR）和等离子体流速（Q >P）计算（60）过滤因子（FF）的装置; 用于将过滤因子（FF）与可接受性的极限值进行比较的第一比较装置（65） 以及用于产生指示比较结果的信号（A）的信令装置（70）。
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公开(公告)号：US20050020958A1
公开(公告)日：2005-01-27
申请号：US10500324
申请日：2002-12-20
CPC分类号： A61M1/34 , A61M1/16 , A61M1/3607 , A61M1/3621 , A61M1/369 , A61M5/44 , A61M2205/3334 , A61M2205/3368 , A61M2205/36 , A61M2230/50
摘要： Control equipment for an extracorporeal blood circuit (2), in which the extracorporeal circuit (2) has an access branch (8) and a return branch (10) connected to a blood treatment element (4; 4, 11a; 4, 11v; 25; 25, 11a; 25, 11v), is provided with a sensor for measuring a first temperature (TP) of the blood leaving a patient (P) along the access branch (8), with a heat exchanger formed by a portion (19) of the return branch (10) and by a device for regulating the temperature (T) of the blood coupled to the portion (19) of the return branch (10), and with a control unit (15) for operating the regulating device (18) as a function of the first temperature (TP) and of a reference temperature (Tset).
摘要翻译： 用于体外血液回路（2）的控制设备，其中体外回路（2）具有接入分支（8）和与血液处理元件（4; 4,11a; 4,11v; 25; 25,11a; 25,11v）设置有用于测量沿着所述进入支路（8）离开患者（P）的血液的第一温度（TP）的传感器，其中热交换器由一部分（ （10）的部分（19）和用于调节与返回分支（10）的部分（19）相连的血液的温度（T）的装置，以及用于操作调节的控制单元（15） 装置（18）作为第一温度（TP）和参考温度（Tset）的函数。
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公开(公告)号：US09791270B2
公开(公告)日：2017-10-17
申请号：US13997532
申请日：2011-12-21
申请人： Francesco Paolini , Paolo Rovatti
发明人： Francesco Paolini , Paolo Rovatti
CPC分类号： G01B13/00 , A61M1/16 , A61M1/34 , A61M1/36 , A61M1/3607 , A61M1/3609 , A61M1/3621 , A61M1/3627 , A61M1/3632 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M2205/123 , A61M2205/3331 , A61M2205/3365 , A61M2205/3379 , A61M2205/50 , A61M2205/502 , A61M2205/60 , A61M2205/6018 , A61M2205/70
摘要： A method to determine a type of blood circuit attached to an extracorporeal blood treatment console including: pumping a liquid through a blood passage of the blood circuit, sensing a first pressure in: the blood passage while the passage is closed and pumping stopped, pumping an additional amount of the liquid into the blood passage while the blood passage is and remains closed and thereafter sensing a second pressure, and determine a dimensional characteristic of a fluid passage in the blood passage based on the additional amount of the liquid and the second pressure.
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6.发明授权Non-invasive device for measuring blood temperature in a circuit for the extracorporeal circulation of blood, and equipment provided with this device 失效用于测量血液体外循环的血液中的血液温度的非侵入性装置以及与该装置一起提供的设备公开(公告)号：US07648475B2
公开(公告)日：2010-01-19
申请号：US10500336
申请日：2002-12-20
申请人： Giorgio De Cicco , Francesco Fontanazzi , Annalisa Delnevo , Massimo Zaccarelli , Francesco Paolini
发明人： Giorgio De Cicco , Francesco Fontanazzi , Annalisa Delnevo , Massimo Zaccarelli , Francesco Paolini
CPC分类号： G01J5/04 , A61M1/367 , A61M2205/3368 , G01J5/0037 , G01J5/061 , G01J5/12 , G01K1/143 , G01K11/006
摘要： A non-invasive device for measuring blood temperature in a circuit for the extracorporeal circulation of blood includes a line in which blood taken from a patient flows. The device also includes a temperature sensor connected to the line and provided with a device for measuring the intensity of an electromagnetic radiation. The measuring device faces a connecting portion or window of the line that is permeable by electromagnetic radiation in a first wave band, and generates a first signal, correlated with the electromagnetic radiation in the first band and therefore with the temperature of the blood flowing in the line.
摘要翻译： 用于测量血液体外循环的回路中的血液温度的非侵入性装置包括其中从患者获取的血液流动的线。 该装置还包括连接到该线路的温度传感器并且设置有用于测量电磁辐射强度的装置。 测量装置面对在第一波段中由电磁辐射渗透的线路的连接部分或窗口，并产生与第一波段中的电磁辐射相关联的第一信号，因此与在 线。
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公开(公告)号：US20080275377A1
公开(公告)日：2008-11-06
申请号：US11913786
申请日：2005-05-18
CPC分类号： A61M1/1086 , A61M1/1006 , A61M1/1039 , A61M1/3655 , A61M2205/3334
摘要： The apparatus for blood flow control in an extracorporeal circuit comprises: a user interface for setting a desired blood flow value (qbREAL) and a datum relating to the vascular access, a memory for recording a plurality of mathematical relations having mathematical expressions relating to the vascular access organ to be used, and a control unit. The control unit identifies the vascular access, selects, from among the plurality of mathematical relations present in the memory, a relation which corresponds to the vascular access identified, and calculates, as a mathematical function of the set value for the desired flow (qbREAL), a value at which to set the angular velocity of the pump associated to the extracorporeal circuit and/or a theoretical value of the arterial pressure upstream of the pump.
摘要翻译： 用于体外循环血流控制的装置包括：用于设置所需血流值（qLBALAL）的用户界面和与血管通路有关的数据;存储器，用于记录多个数学 具有与要使用的血管通路器官有关的数学表达式的关系，以及控制单元。 控制单元识别血管通路，从存储器中存在的多个数学关系中选择对应于所识别的血管通路的关系，并计算出所需流量的设定值的数学函数（q < SUB> bREAL ），用于设定与体外循环相关的泵的角速度和/或泵的上游的动脉压的理论值的值。
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公开(公告)号：US07067061B2
公开(公告)日：2006-06-27
申请号：US10844422
申请日：2004-05-13
申请人： Antonio Bosetto , Francesco Paolini
发明人： Antonio Bosetto , Francesco Paolini
CPC分类号： A61M1/1656 , A61M1/1666 , A61M1/167 , B01F3/088 , Y10S210/929
摘要： A method for preparing a medical liquid from a liquid, such as water, and two concentrated solutions comprises the following steps: circulating the liquid in a conduit (15), at a flowrate Q0; injecting into the conduit (15), at a flowrate Q1, a first concentrated solution containing a first ionic substance A and a second ionic substance B, the ionic substances A and B having, respectively, in the first concentrated solution, a concentration [Asol] and a first concentration [B1sol]; injecting into the conduit (15), at a flowrate Q2, a second concentrated solution containing the first ionic substance A and the second ionic substance B, the first ionic substance A having, in the second concentrated solution, the same concentration [Asol] as in the first concentrated solution, and the second ionic substance B having, in the second concentrated solution, a second concentration [B2sol] different than the first concentration [B1sol] in the first concentrated solution; regulating the injection flowrate Q1 and the injection flowrate Q2 of the first and second concentrated solutions in such a way that at any given time the diluted solution resulting from the mixing of the liquid and the concentrated solutions has a desired concentration [Ades] of first substance A and a desired concentration [Bdes] of second substance B.
摘要翻译： 从液体如水和两种浓缩溶液制备医用液体的方法包括以下步骤：以流量Q 0在管道（15）中循环液体; 以流量Q 1，含有第一离子物质A和第二离子物质B的第一浓缩溶液将第一浓缩溶液中的离子物质A和B分别注入管道（15）中， Asol]和第一浓度[B 1 sol]; 以流量Q 2，含有第一离子物质A和第二离子物质B的第二浓缩溶液注入到管道（15）中，第一离子物质A在第二浓缩溶液中具有相同的浓度[Asol] 与第一浓缩溶液一样，第二离子物质B在第二浓缩溶液中具有与第一浓缩溶液中的第一浓度[B 1 sol]不同的第二浓度[B 2 sol] 调节第一和第二浓缩溶液的注入流量Q 1和注入流速Q 2，使得在任何给定时间，由液体和浓缩溶液的混合产生的稀释溶液具有所需的浓度[Ades] 第一物质A和第二物质B的所需浓度[Bdes]
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9.发明授权Method for measuring hemoglobin concentration (HGB) in the blood in a circuit of a dialysis machine, measuring device and circuit for the application of the method 有权用于测量透析机电路血液中血红蛋白浓度（HGB）的方法，测量装置和应用该方法的电路公开(公告)号：US06794194B2
公开(公告)日：2004-09-21
申请号：US10258117
申请日：2002-10-21
IPC分类号： G01N3372
CPC分类号： G01N21/31 , A61B5/14557 , A61M1/3639 , A61M1/3641 , A61M1/367 , A61M2230/207 , G01N21/35 , G01N21/359 , G01N21/85
摘要： A method for measuring the hemoglobin concentration in the blood in a circuit of a dialysis machine includes directing electromagnetic waves against one section of the circuit, measuring values of the electromagnetic waves transmitted through the section, and determining values of absorption of electromagnetic waves by the blood along the section from the measured values of transmitted electromagnetic waves. The values of absorption are correlated with the values of the hemoglobin concentration. The method also includes measuring the values of at least one physical quantity of the blood, wherein the at least one physical quantity is selected from blood pressure and blood temperature, and calculating the values of hemoglobin concentration as a function of the values of absorption and the at least one physical quantity.
摘要翻译： 一种用于测量透析机电路中血液中血红蛋白浓度的方法，包括对电路的一部分引导电磁波，测量通过该部分传输的电磁波的值，以及确定血液中电磁波的吸收值 沿着发射电磁波的测量值的一部分。 吸收值与血红蛋白浓度的值相关。 该方法还包括测量血液的至少一个物理量的值，其中所述至少一个物理量选自血压和血液温度，并且计算作为吸收值的函数的血红蛋白浓度值 至少一个物理量。
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10.发明授权公开(公告)号：US06691040B2
公开(公告)日：2004-02-10
申请号：US09726484
申请日：2000-12-01
申请人： Antonio Bosetto , Francesco Paolini
发明人： Antonio Bosetto , Francesco Paolini
IPC分类号： G01N3348
CPC分类号： A61M1/16 , A61M1/1607 , A61M1/1609 , A61M1/1613 , A61M1/1617 , A61M2205/3317 , A61M2205/3324 , A61M2205/52
摘要： A method for continuously determining a parameter (D, Cbin, K, Kt/V) indicative of an extracorporeal blood treatment includes flowing patient's blood and a treatment liquid flow on opposite sides of a semipermeable membrane. The treatment liquid has a characteristic (Cd) associated with the effectiveness of the treatment flow through the exchanger. A succession of variations are caused in the characteristic (Cd) upstream of the exchanger, and a plurality of values (Cdin1 . . . Cdinj . . . Cdinp) of the characteristic (Cd) upstream of the exchanger are continuously stored in memory. Similarly, plurality of values (Cdout1 . . . Cdoutj . . . Cdoutp) adopted by the characteristic (Cd) downstream of the exchanger are continuously stored in memory. From the stored values, the effectiveness of the treatment is calculated using a mathematical model.
摘要翻译： 用于连续地确定表示体外血液处理的参数（D，Cbin，K，Kt / V）的方法包括在半透膜的相对侧流动患者的血液和处理液体流。 处理液具有与通过交换器的处理流的有效性相关的特征（Cd）。 在交换器上游的特征（Cd）中引起了一系列变化，并且交换机上游特征（Cd）的多个值（Cdin1。Cdinj。Cdinp）连续存储在存储器中。 类似地，由交换机下游特性（Cd）采用的多个值（Cdout1。Cdoutj。Cdoutp）连续存储在存储器中。 从存储的值中，使用数学模型计算治疗的有效性。
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