公开(公告)号：US5107214A

公开(公告)日：1992-04-21

申请号：US602242

申请日：1990-11-07

申请人： Mitsuo Yoshida ,  Shigeyuki Nitta ,  Kazuyoshi Miyazawa ,  Katsumi Taguchi ,  Masaki Fujiwara

发明人： Mitsuo Yoshida ,  Shigeyuki Nitta ,  Kazuyoshi Miyazawa ,  Katsumi Taguchi ,  Masaki Fujiwara

IPC分类号： G01N29/04 ,  B21B38/00 ,  G01N27/90 ,  G01N29/22

CPC分类号： G01N27/9026 ,  G01N27/9006 ,  G01N27/9033 ,  B21B38/00 ,  G01N2291/0234 ,  G01N2291/044

摘要： A hot flaw detector is equipped with a sensor holding member that has a circular opening through which the material to be inspected will pass and that holds a flaw detecting sensor. Provision is made of an annular cooling liquid injection port that is open at an end of the sensor holding member adjacent to the inner peripheral wall of the circular opening, and provision is further made of an annular cooling liquid introduction port that is open at the other end of the sensor holding member adjacent to the inner peripheral wall of the circular opening. The cooling liquid is injected from the annular cooling liquid injection port, and forms a liquid film along the inner peripheral wall of the circular opening, and is recovered through the annular cooling liquid introduction port. The inner peripheral wall of the sensor holding member is effectively cooled by the liquid film which drips little onto the material to be inspected.

摘要翻译： PCT No.PCT / JP90 / 00296 Sec。 371日期1990年11月7日 102（e）1990年11月7日PCT PCT 1990年3月7日PCT公布。 出版物WO90 / 10864 1990年9月20日。热瑕疵检测器配有传感器保持构件，传感器保持构件具有圆形开口，待检查材料将通过该开口，并保持探伤传感器。 设置有环形冷却液注入口，该环形冷却液注入口在传感器保持构件的与圆形开口的内周壁相邻的端部处开口，并且还设置在另一个开口的环形冷却液引入口 传感器保持构件的端部与圆形开口的内周壁相邻。 冷却液从环状冷却液注入口喷出，沿着圆形开口的内周壁形成液膜，通过环状冷却液导入口回收。 传感器保持构件的内周壁由液膜有效地冷却，液膜几乎滴落到被检查材料上。

公开(公告)号：US09223209B2

公开(公告)日：2015-12-29

申请号：US12709346

申请日：2010-02-19

申请人： Daniel Paul Sanders ,  Masaki Fujiwara ,  Yoshiharu Terui

发明人： Daniel Paul Sanders ,  Masaki Fujiwara ,  Yoshiharu Terui

IPC分类号： G03F7/039 ,  G03F7/20 ,  G03F7/004 ,  G03F7/11 ,  G03F7/32

CPC分类号： G03F7/0046 ,  G03F7/0392 ,  G03F7/0397 ,  G03F7/11 ,  G03F7/2041 ,  G03F7/322 ,  G03F7/325

摘要： Provided are sulfonamide-containing photoresist compositions for use in lithographic processes that have improved properties for high resolution, low blur imaging. Also provided are alcohol-soluble photoresists for resist-on-resist applications. The sulfonamide-containing photoresist compositions of the present invention include positive-tone photoresist compositions that have sulfonamide-substituted repeat units with branched linking group as shown in Formula (I):

摘要翻译： 提供了用于光刻工艺的含磺酰胺的光致抗蚀剂组合物，其具有用于高分辨率，低模糊成像的改进的性质。 还提供了用于抗蚀剂抗蚀剂应用的醇溶性光致抗蚀剂。 本发明的含磺酰胺的光致抗蚀剂组合物包括具有如式（I）所示的具有支链连接基团的磺酰胺取代的重复单元的正色调光致抗蚀剂组合物：

公开(公告)号：US08940138B2

公开(公告)日：2015-01-27

申请号：US12935803

申请日：2009-04-02

申请人： Masaki Fujiwara

发明人： Masaki Fujiwara

IPC分类号： C12Q1/00 ,  C12Q1/26 ,  C12M1/34 ,  G01N27/327 ,  A61B5/15 ,  A61B5/145

CPC分类号： G01N27/3273 ,  C12Q1/26 ,  G01N27/3274

摘要： The present biosensor system prevents a measurement error caused by the temperature of the environment in use. A biosensor system 100 includes a measuring instrument 101 having an operation part 306, and a sensor chip 200 insertable into and removable from the measuring instrument 101 and which accepts a blood sample. The sensor chip 200 includes a measurement part 41 that acquires Data a related to the concentration of an analyte in a blood sample based on the amount of electric current that flows in the sample due to a reaction in which an oxidoreductase with the analyte used as a substrate is involved, and a measurement part 42 that acquires, from the sample, Data b for temperature correction of Data a. The operation part 306 determines the concentration of the analyte in the sample, corrected according to the temperature of the sample based on Data a and Data b.

摘要翻译： 本生物传感器系统防止由使用环境的温度引起的测量误差。 生物传感器系统100包括具有操作部306的测量仪器101和可插入测量仪器101并可从测量仪器101移除并且接受血液样本的传感器芯片200。 传感器芯片200包括测量部分41，该测量部分41基于由于其中使用分析物的氧化还原酶的反应而在样品中流动的电流量来获取与血液样品中的分析物的浓度相关的Data a 涉及基板;以及测量部42，其从该样本获取用于Data a的温度校正的Data b。 操作部306根据数据a和数据b，根据样本的温度来确定样品中分析物的浓度。

公开(公告)号：US08859292B2

公开(公告)日：2014-10-14

申请号：US13144790

申请日：2010-01-28

申请人： Masaki Fujiwara

发明人： Masaki Fujiwara

IPC分类号： G01N27/416 ,  C12Q1/54 ,  G01N27/327

CPC分类号： G01N27/3274 ,  B01L3/502 ,  B01L2200/147 ,  B01L2300/0645 ,  B01L2400/0406 ,  C12Q1/004 ,  C12Q1/006 ,  C12Q1/54 ,  G01K7/00 ,  G01N27/26 ,  G01N27/28 ,  G01N27/327 ,  G01N27/3272 ,  G01N27/3273 ,  G01N27/416 ,  Y10T436/144444

摘要： A sensor chip is configured to measure the temperature of a blood sample and includes a capillary section and an electrode unit. The capillary section allows the blood sample to be introduced therein. The electrode unit is configured to measure the temperature of the blood sample and includes a working electrode and a counter electrode. The working electrode and the counter electrode respectively include a reaction reagent layer containing an electrolyte. Further, the electrode unit is configured to receive a predetermined voltage to be applied in measuring the temperature of the blood sample for allowing a result of the measurement to be less affected by increase and reduction in a glucose concentration and the like.

摘要翻译： 传感器芯片被配置为测量血液样本的温度，并且包括毛细管部分和电极单元。 毛细管部分允许将血液样品引入其中。 电极单元被配置为测量血液样本的温度，并且包括工作电极和对电极。 工作电极和对电极分别包含含有电解质的反应试剂层。 此外，电极单元被配置为在测量血液样本的温度时接受预定的电压，以允许测量结果受葡萄糖浓度的增加和降低等的影响较小。

公开(公告)号：US08480869B2

公开(公告)日：2013-07-09

申请号：US13279787

申请日：2011-10-24

申请人： Masaki Fujiwara ,  Teppei Shinno ,  Shin Ikeda

发明人： Masaki Fujiwara ,  Teppei Shinno ,  Shin Ikeda

IPC分类号： G01N27/327

CPC分类号： G01N27/3274

摘要： The present invention provides a method of electrochemically measuring a hematocrit (Hct) value using a sensor, capable of achieving excellent measurement accuracy and reliability and also provides a sensor used in the method. The method of electrochemically measuring a hematocrit (Hct) value of blood include: providing an electrode system having a working electrode (11) and a counter electrode (12), in which a redox substance is provided on the counter electrode (12) but not on the working electrode (11); supplying blood to the electrode system; applying a voltage to the electrode system in this state to cause an oxidation current or a reduction current to flow between the working electrode (11) and the counter electrode (12); detecting the oxidation current or the reduction current; and determining a Hct value based on a value of the detected current.

摘要翻译： 本发明提供一种使用传感器电化学测量血细胞比容（Hct）值的方法，其能够实现优异的测量精度和可靠性，并且还提供了该方法中使用的传感器。 电化学测量血液血细胞比容（Hct）值的方法包括：提供具有工作电极（11）和对电极（12）的电极系统，其中在对电极（12）上设置氧化还原物质 在工作电极（11）上; 向电极系统供应血液; 在该状态下向电极系统施加电压，使得氧化电流或还原电流在工作电极（11）和对电极（12）之间流动。 检测氧化电流或还原电流; 以及基于检测到的电流的值确定Hct值。

公开(公告)号：US08444576B2

公开(公告)日：2013-05-21

申请号：US13237157

申请日：2011-09-20

申请人： Masaki Fujiwara ,  Yoshinori Amano

发明人： Masaki Fujiwara ,  Yoshinori Amano

IPC分类号： A61B5/00 ,  A61B5/151 ,  A61B5/157

CPC分类号： A61B5/157 ,  A61B5/14532 ,  A61B5/14535 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150099 ,  A61B5/15019 ,  A61B5/150213 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150519 ,  A61B5/15087 ,  A61B5/15117 ,  A61B5/1513 ,  A61B5/1519 ,  A61B2562/0295

摘要： A blood test apparatus has a housing, a blood sensor, and a plurality of connectors. The blood sensor has a plurality of connection terminals that are electrically connected with each electrode of the electrode system; and a reference terminal that serves as a reference. The plurality of connectors are configured to connect to the plurality of connection terminals and the reference terminal of the blood sensor attached at a predetermined position in the blood test apparatus, respectively. And also, relations between the reference terminal and each of the plurality of connection terminals are measured to identify the reference terminal automatically.

摘要翻译： 血液检查装置具有壳体，血液传感器和多个连接器。 血液传感器具有与电极系统的每个电极电连接的多个连接端子; 以及作为参考的参考端子。 多个连接器被配置为分别连接到血液检查装置中的预定位置处的多个连接端子和血液传感器的参考端子。 并且，还测量参考终端与多个连接终端中的每一个之间的关系以自动识别参考终端。

公开(公告)号：US08207351B2

公开(公告)日：2012-06-26

申请号：US12770877

申请日：2010-04-30

申请人： Masaki Fujiwara ,  James Lupton Hedrick ,  Daniel Paul Sanders ,  Manabu Yasumoto

发明人： Masaki Fujiwara ,  James Lupton Hedrick ,  Daniel Paul Sanders ,  Manabu Yasumoto

IPC分类号： C07D263/00

CPC分类号： C07D319/04 ,  C07D317/36 ,  C08G64/0233 ,  C08G64/30 ,  Y02P20/582

摘要： A one pot method of preparing cyclic carbonyl compounds comprising an active pendant pentafluorophenyl carbonate group is disclosed. The cyclic carbonyl compounds can be polymerized by ring opening methods to form ROP polymers comprising repeat units comprising a side chain pentafluorophenyl carbonate group. Using a suitable nucleophile, the pendant pentafluorophenyl carbonate group can be selectively transformed into a variety of other functional groups before or after the ring opening polymerization.

摘要翻译： 公开了一种制备包含活性五氟苯基碳酸酯基团的环状羰基化合物的一锅法。 环状羰基化合物可以通过开环方法聚合以形成包含包含侧链五氟苯基碳酸酯基团的重复单元的ROP聚合物。 使用合适的亲核试剂，可以在开环聚合之前或之后将五氟苯基碳酸五酯基团选择性地转化成多种其它官能团。

公开(公告)号：US08206318B2

公开(公告)日：2012-06-26

申请号：US12293626

申请日：2007-03-22

申请人： Motonori Uchiyama ,  Masaki Fujiwara ,  Toshihiro Akiyama ,  Yoshinori Amano

发明人： Motonori Uchiyama ,  Masaki Fujiwara ,  Toshihiro Akiyama ,  Yoshinori Amano

IPC分类号： A61B5/00

CPC分类号： A61B5/157 ,  A61B5/150022 ,  A61B5/150099 ,  A61B5/150213 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150519 ,  A61B5/150954 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15134 ,  A61B5/15138 ,  A61B5/1519

摘要： It is intended to provide a means of easily removing a portion of blood bleeding from pierced skin, which has not been taken into a blood sensor but remained on the skin, in a blood test with the use of a blood test apparatus. By using this means, it becomes unnecessary in the blood test to separately prepare a paper sheet, etc. for wiping off. More specifically speaking, a blood test apparatus wherein a blood sensor is provided within a blood sensor unit detachable to the blood test apparatus body and the blood sensor unit has a part to be in contact with the skin in the test and an absorption means. It is favorable that the part to be in contact with the skin in the test serves as the absorption means.

摘要翻译： 本发明旨在提供一种在使用血液检查装置的血液检查中，能够容易地除去未被吸入血液传感器而残留在皮肤上的被刺穿的皮肤的一部分血液渗出的手段。 通过使用这种方式，在血液检查中不需要分别制作用于擦除的纸张等。 更具体地说，一种血液检查装置，其中血液传感器设置在可与血液检查装置主体分离的血液传感器单元内，并且血液传感器单元具有在测试中与皮肤接触的部分和吸收装置。 在试验中与皮肤接触的部分作为吸收手段是有利的。

公开(公告)号：US20120037506A1

公开(公告)日：2012-02-16

申请号：US13279787

申请日：2011-10-24

申请人： Masaki Fujiwara ,  Teppei Shinno ,  Shin Ikeda

发明人： Masaki Fujiwara ,  Teppei Shinno ,  Shin Ikeda

IPC分类号： G01N27/327 ,  G01N33/50

CPC分类号： G01N27/3274

摘要： The present invention provides a method of electrochemically measuring a hematocrit (Hct) value using a sensor, capable of achieving excellent measurement accuracy and reliability and also provides a sensor used in the method. The method of electrochemically measuring a hematocrit (Hct) value of blood include: providing an electrode system having a working electrode (11) and a counter electrode (12), in which a redox substance is provided on the counter electrode (12) but not on the working electrode (11); supplying blood to the electrode system; applying a voltage to the electrode system in this state to cause an oxidation current or a reduction current to flow between the working electrode (11) and the counter electrode (12); detecting the oxidation current or the reduction current; and determining a Hct value based on a value of the detected current.

摘要翻译： 本发明提供一种使用传感器电化学测量血细胞比容（Hct）值的方法，其能够实现优异的测量精度和可靠性，并且还提供了该方法中使用的传感器。 电化学测量血液血细胞比容（Hct）值的方法包括：提供具有工作电极（11）和对电极（12）的电极系统，其中在对电极（12）上设置氧化还原物质 在工作电极（11）上; 向电极系统供应血液; 在该状态下向电极系统施加电压，使得氧化电流或还原电流在工作电极（11）和对电极（12）之间流动。 检测氧化电流或还原电流; 以及基于检测到的电流的值确定Hct值。

公开(公告)号：US20110319652A1

公开(公告)日：2011-12-29

申请号：US13223605

申请日：2011-09-01

申请人： Jonathan Joachim Jodry ,  Masashi Nagamori ,  Yuji Hagiwara ,  Masaki Fujiwara ,  Satoru Narizuka

发明人： Jonathan Joachim Jodry ,  Masashi Nagamori ,  Yuji Hagiwara ,  Masaki Fujiwara ,  Satoru Narizuka

IPC分类号： C07C69/54

CPC分类号： C07C309/17 ,  C07C29/147 ,  C07C67/08 ,  C07C67/14 ,  C07C303/32 ,  C07C309/08 ,  C07C309/12 ,  C07C313/04 ,  C07C381/12 ,  C07C2602/42 ,  C07C2603/74 ,  G03F7/0045 ,  G03F7/0046 ,  C07C31/34 ,  C07C69/653 ,  C07C69/63 ,  C07C69/753

摘要： Disclosed is a process for producing 2-bromo-2,2-difluoroethanol, which comprises reducing a bromodifluoroacetic acid derivative represented by the formula [1] by using an ate hydride complex as a reducing agent. 2-Bromo-2,2-difluoroethanol thus produced can be used as the starting material to carry out the esterification step, the sulfination step and the oxidation step in this order, thereby producing a 2-alkylcarbonyloxy-1,1-difluoroethanesulfonic acid salt, wherein A represents a substituted or unsubstituted linear, branched or cyclic alkoxy group having 1 to 20 carbon atoms, a substituted or unsubstituted aryloxy group having 6 to 15 carbon atoms, a heteroaryloxy group having 4 to 15 carbon atoms, or a halogen atom.

摘要翻译： 公开了一种2-溴-2,2-二氟乙醇的制备方法，其包括使用氢化物​​络合物作为还原剂还原式[1]表示的溴二氟乙酸衍生物。 可以使用如此制备的2-溴-2,2-二氟乙醇作为起始原料，依次进行酯化步骤，硫化步骤和氧化步骤，由此制备2-烷基羰基氧基-1,1-二氟乙磺酸盐 其中A表示取代或未取代的具有1至20个碳原子的直链，支链或环状烷氧基，取代或未取代的碳原子数6〜15的芳氧基，碳原子数4〜15的杂芳氧基或卤素原子。