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公开(公告)号：US20090270022A1
公开(公告)日：2009-10-29
申请号：US12148833
申请日：2008-04-23
申请人： Mukesh Kumar , Paul Hoke , Mark Doroudian
发明人： Mukesh Kumar , Paul Hoke , Mark Doroudian
IPC分类号： B60H1/26
CPC分类号： B60H1/00564 , B60H1/242 , B60H1/246 , B60H2001/00092
摘要： A climate control duct architecture having partitions to provide effective distribution of air immediately as it exits the HVAC. By strategic positioning and configuring of the partitions the duct architecture may be tuned to provide maximum console airflow and desired system airflow distribution with a minimum amount of interference to the airflow due to turbulence.
摘要翻译： 一种气候控制管道结构，具有隔板，以便在离开暖通空调时立即提供有效的空气分配。 通过战略定位和配置分区，管道架构可以被调整以提供最大的控制台气流和期望的系统气流分布，由于湍流对气流具有最小量的干扰。
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公开(公告)号：US08608532B2
公开(公告)日：2013-12-17
申请号：US12148833
申请日：2008-04-23
申请人： Mukesh Kumar , Paul Hoke , Mark Doroudian
发明人： Mukesh Kumar , Paul Hoke , Mark Doroudian
CPC分类号： B60H1/00564 , B60H1/242 , B60H1/246 , B60H2001/00092
摘要： A climate control duct architecture having partitions to provide effective distribution of air immediately as it exits the HVAC. By strategic positioning and configuring of the partitions the duct architecture may be tuned to provide maximum console airflow and desired system airflow distribution with a minimum amount of interference to the airflow due to turbulence.
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3.发明授权公开(公告)号：US09102215B2
公开(公告)日：2015-08-11
申请号：US13274729
申请日：2011-10-17
申请人： Mukesh Kumar , Paul B. Hoke , Martha E. Nefcy , David Wong
发明人： Mukesh Kumar , Paul B. Hoke , Martha E. Nefcy , David Wong
CPC分类号： B60H1/00842 , B60H1/00021 , B60H1/00735 , B60H1/00742 , B60H2001/002 , F24F11/30 , F24F2110/00 , F24F2110/10 , F24F2120/10
摘要： A comfort system is provided for a motor vehicle. A seat occupancy sensor determines whether a third row zone is occupied. At least one flow controller is provided in the floor duct for controllably supplying the conditioned airflow to at least the third row outlet. If the third row zone is occupied, then a second row outlet and the third row outlet are turned on to supply a conditioned airflow to a front seat zone, a second row zone, and the third row zone. If the third row zone is not occupied, then the third row outlet is closed off. If the second row zone is not occupied, then the second and third row outlets are closed off. If occupied, then the second row outlet is turned on until a desired comfort level is achieved in the second row zone.
摘要翻译： 为汽车提供舒适系统。 座椅占用传感器确定第三行区域是否被占用。 至少一个流量控制器设置在地板管道中，用于可控地将经调节的气流提供给至少第三排出口。 如果第三排区域被占用，则第二排出口和第三排出口被打开以向前排座位区域，第二排区域和第三行区域提供经调节的气流。 如果第三排区域未被占用，则第三行出口被关闭。 如果第二行区域未被占用，则第二和第三行出口被关闭。 如果被占用，则第二排出口被打开，直到在第二行区域中达到期望的舒适度。
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公开(公告)号：US08641134B2
公开(公告)日：2014-02-04
申请号：US13437423
申请日：2012-04-02
申请人： Robert S. Sawyer , Mukesh Kumar , Martha E. Nefcy
发明人： Robert S. Sawyer , Mukesh Kumar , Martha E. Nefcy
IPC分类号： B60H1/24
CPC分类号： B60H1/00564 , B60H1/245 , B60H1/246
摘要： An air duct for an automotive vehicle is blow molded with an elongated, hollow structural member to be used as a portion of a body of the vehicle. The structural member has an inner wall defining an elongated cavity communicating with first and second access holes at respective longitudinal positions along the structural member. A parison comprised of a thermally insulating material is inserted into the internal cavity. A source of inflation gas is connected to a mouth portion or the parison. The parison is heated and inflated within the internal cavity to an expanded shape to form the air duct disposed against the inner wall and spanning the first and second access holes. The air duct at one of the access holes is configured as an air inlet. The air duct at the other one of the access holes is configured as an air outlet.
摘要翻译： 用于机动车辆的空气管道是吹塑成型的，具有细长的中空结构件，用作车身的一部分。 结构构件具有限定在沿着结构构件的各个纵向位置处与第一和第二进入孔连通的细长腔的内壁。 将由隔热材料构成的型坯插入内部空腔。 膨胀气体源连接到口部或型坯。 型坯在内腔内被加热膨胀成扩张形状，以形成靠在内壁上并横跨第一和第二进入孔的空气通道。 一个进入孔的空气管道被构造为空气入口。 在另一个进入孔的空气管道被配置为空气出口。
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公开(公告)号：US20130257106A1
公开(公告)日：2013-10-03
申请号：US13437423
申请日：2012-04-02
申请人： Robert S. Sawyer , Mukesh Kumar , Martha E. Nefcy
发明人： Robert S. Sawyer , Mukesh Kumar , Martha E. Nefcy
CPC分类号： B60H1/00564 , B60H1/245 , B60H1/246
摘要： An air duct for an automotive vehicle is blow molded with an elongated, hollow structural member to be used as a portion of a body of the vehicle. The structural member has an inner wall defining an elongated cavity communicating with first and second access holes at respective longitudinal positions along the structural member. A parison comprised of a thermally insulating material is inserted into the internal cavity. A source of inflation gas is connected to a mouth portion or the parison. The parison is heated and inflated within the internal cavity to an expanded shape to form the air duct disposed against the inner wall and spanning the first and second access holes. The air duct at one of the access holes is configured as an air inlet. The air duct at the other one of the access holes is configured as an air outlet.
摘要翻译： 用于机动车辆的空气管道是吹塑成型的，具有细长的中空结构件，用作车身的一部分。 结构构件具有限定在沿着结构构件的各个纵向位置处与第一和第二进入孔连通的细长腔的内壁。 将由隔热材料构成的型坯插入内部空腔。 膨胀气体源连接到口部或型坯。 型坯在内腔内被加热膨胀成扩张形状，以形成靠在内壁上并横跨第一和第二进入孔的空气通道。 一个进入孔的空气管道被构造为空气入口。 在另一个进入孔的空气管道被配置为空气出口。
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公开(公告)号：US20130204389A1
公开(公告)日：2013-08-08
申请号：US13366510
申请日：2012-02-06
IPC分类号： A61F2/32
CPC分类号： A61F2/3609 , A61F2002/30332 , A61F2002/30589 , A61F2002/30682 , A61F2002/365
摘要： A seal for preventing a bodily fluid from penetrating an orthopedic implant comprising a tapered section adapted to conformingly mate to a stem of a first implant component, and a collar section extending from and circumferentially surrounding a portion of the tapered section, the collar section adapted to mate to a base of a second implant component such that the tapered section and collar section define an opening therethrough configured to receive the first implant component.
摘要翻译： 一种用于防止体液穿透整形外科植入物的密封件，包括适于与第一植入部件的杆顺从地配合的锥形部分，以及从锥形部分的一部分延伸并周向围绕锥形部分的颈环部分， 配合到第二植入部件的基部，使得锥形部分和凸缘部分限定通过其构造成接收第一植入部件的开口。
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公开(公告)号：US20110218644A1
公开(公告)日：2011-09-08
申请号：US13039362
申请日：2011-03-03
申请人： Jason Meridew , Mukesh Kumar , Tayler E. Kreider
发明人： Jason Meridew , Mukesh Kumar , Tayler E. Kreider
CPC分类号： A61M5/14 , A61F2/34 , A61F2/3662 , A61F2/389 , A61F2002/3068 , A61F2002/368 , A61F2002/3694 , A61M5/14276 , A61M39/0208 , A61M2205/3523 , A61M2210/086
摘要： A drug delivery and diagnostic system can include an orthopedic implant having an outer attachment surface. A conduit can be coupled to the outer attachment surface. The conduit can have an inlet and a plurality of perforations formed along a length thereof. The conduit can be adapted to pass fluid between the inlet and the perforations. A subcutaneous port can be fluidly coupled to the inlet and be adapted to communicate fluid through the inlet, along the conduit and out of the perforations around and along the outer attachment surface of the orthopedic implant.
摘要翻译： 药物递送和诊断系统可以包括具有外部附接表面的矫形植入物。 管道可以联接到外部附接表面。 导管可以具有沿其长度形成的入口和多个穿孔。 导管可适于在入口和穿孔之间传递流体。 皮下端口可以流体地联接到入口，并且适于沿着导管和通过整形外科植入物的外部附接表面的穿孔穿过入口传送流体。
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公开(公告)号：US20110052601A1
公开(公告)日：2011-03-03
申请号：US12390246
申请日：2009-02-20
申请人： Shyam S. Mohapatra , Aruna Behera , Hiroto Matsuse , Mukesh Kumar
发明人： Shyam S. Mohapatra , Aruna Behera , Hiroto Matsuse , Mukesh Kumar
CPC分类号： C12N15/1138 , C12N15/111 , C12N2310/11 , C12N2320/32
摘要： There is provided a method of preventing a respiratory infection by administering an effective amount of an agent for regulating ICAM-1 expression. Also provided is a composition for the prevention of respiratory infection including an agent which regulates ICAM expression. method of preventing RSV infection by administering an effective amount of an agent that interferes with the binding of RSV to ICAM-1. A method of preventing RSV infection by administering an effective amount of an agent that down regulates the expression of ICAM-1, thereby decreasing RSV binding to ICAM-1 is also provided. There is provided a method of treating RSV infection by administering an effective amount of an agent for down regulating ICAM-1 expression. A method of blocking RSV-ICAM-1 interaction by administering an effective amount of agents for blocking ICAM sites of binding is provided. Also provided is a compound for blocking RSV-ICAM-1 interaction including an agent for blocking ICAM sites of binding.
摘要翻译： 提供了一种通过施用有效量的用于调节ICAM-1表达的试剂来预防呼吸道感染的方法。 还提供了用于预防呼吸道感染的组合物，包括调节ICAM表达的药剂。 通过施用有效量的妨碍RSV与ICAM-1的结合的试剂来预防RSV感染的方法。 还提供了通过施用有效量的下调ICAM-1的表达的试剂，从而降低RSV与ICAM-1的结合来预防RSV感染的方法。 提供了通过施用有效量的用于下调ICAM-1表达的试剂来治疗RSV感染的方法。 提供了通过施用有效量的阻断ICAM结合位点的试剂阻断RSV-ICAM-1相互作用的方法。 还提供了用于阻断RSV-ICAM-1相互作用的化合物，其包括用于阻断结合的ICAM位点的试剂。
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公开(公告)号：US20100100191A1
公开(公告)日：2010-04-22
申请号：US12579479
申请日：2009-10-15
申请人： Brian M. May , Mukesh Kumar
发明人： Brian M. May , Mukesh Kumar
CPC分类号： A61F2/389 , A61F2/30767 , A61F2/30965 , A61F2002/30769 , A61F2002/30879 , A61F2002/30881 , A61F2002/30883 , A61F2002/30884 , A61F2002/3092 , A61F2240/001 , A61F2310/00023 , A61F2310/00179
摘要： A knee joint prosthesis can include a tibial component that can have a tibial tray. The tibial tray can include a platform-like tray that defines a superior surface and an inferior surface. The platform-like tray can have a tray perimeter and a raised wall formed on the inferior surface. The raised wall can be offset inboard relative to the tray perimeter. Porous material can be disposed on the inferior surface of the platform-like tray at a location generally between the raised wall and the tray perimeter.
摘要翻译： 膝关节假体可以包括可具有胫骨托的胫骨部件。 胫骨托可包括限定上表面和下表面的平台状托盘。 平台状托盘可以具有托盘周边和形成在下表面上的凸起壁。 凸起的壁可以相对于托盘周边在内侧偏移。 多孔材料可以在通常在凸起壁和托盘周边之间的位置处设置在平台状托盘的下表面上。
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公开(公告)号：US07699987B2
公开(公告)日：2010-04-20
申请号：US11449476
申请日：2006-06-08
申请人： Anand C. Burman , Rama Mukherjee , Dinesh Kumar , Dhiraj Khattar , Mukesh Kumar , Praveen Khullar , Perundurai S. Srinivasan , Rajesh Srivastava
发明人： Anand C. Burman , Rama Mukherjee , Dinesh Kumar , Dhiraj Khattar , Mukesh Kumar , Praveen Khullar , Perundurai S. Srinivasan , Rajesh Srivastava
IPC分类号： B01D15/08
CPC分类号： C07D305/14 , A61K47/44 , B01D15/325 , B01J20/287
摘要： A stabilized pharmaceutical composition of anticancer drug and a solvent like Polyethoxylated castor oil (cremophor) also containing any other suitable solubilizer suitable for human administration like dehydrated alcohol, is disclosed. Compositions prepared using this purified polyethoxylated castor oil enhance the stability of paclitaxel in such compositions.
摘要翻译： 公开了一种稳定的抗癌药物和溶剂，如聚乙氧基化蓖麻油（cremophor）的药物组合物，其也含有适于人类给药的任何其它合适的增溶剂如脱水醇。 使用该纯化的聚乙氧基化蓖麻油制备的组合物增强紫杉醇在这些组合物中的稳定性。
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