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公开(公告)号：US08425493B2
公开(公告)日：2013-04-23
申请号：US10515152
申请日：2003-05-20
IPC分类号： A61K9/22
CPC分类号： A61M5/14224 , A61M5/14276 , A61M39/0208 , A61M2005/14264 , A61M2039/242 , A61M2210/0693
摘要： An implantable medication delivery device that is highly space efficient and can reliably and safely deliver controlled medication doses to a target site. The system includes a variable volume medication reservoir that is exposed to an ambient pressure equal to the ambient pressure at a system outlet port. A pump/valve subassembly is provided to draw medication from the reservoir and force a medication dose along a fluid transfer passageway to the outlet port. The pump/valve subassembly incorporates a safety mechanism, e.g., a balanced valve, which normally blocks medication flow to the outlet port and opens only in response to a pump induced unbalancing force. A protective shell is also disclosed for protecting the ambient reservoir.
摘要翻译： 可植入药物输送装置，其具有高度的空间效率并能可靠且安全地将受控的药物剂量递送至目标部位。 该系统包括暴露于等于系统出口处的环境压力的环境压力的可变体积药物储存器。 提供泵/阀子组件以从储存器抽取药物并且迫使药物剂量沿流体输送通道流到出口。 泵/阀子组件包括安全机构，例如平衡阀，其通常阻止药物流向出口并且仅响应于泵引起的不平衡力而打开。 还公开了用于保护环境储存器的保护壳。
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公开(公告)号：US06740075B2
公开(公告)日：2004-05-25
申请号：US09768204
申请日：2001-01-22
申请人： Ronald J. Lebel , Varaz Shahmirian , Timothy J. Starkweather , Daniel H. Villegas , David Y. Choy , Philip T. Weiss , Colin A. Chong , Peter C. Lord , Wayne A. Morgan , Paul M. Meadows
发明人： Ronald J. Lebel , Varaz Shahmirian , Timothy J. Starkweather , Daniel H. Villegas , David Y. Choy , Philip T. Weiss , Colin A. Chong , Peter C. Lord , Wayne A. Morgan , Paul M. Meadows
IPC分类号： A61K922
CPC分类号： A61M5/172 , A61B5/0002 , A61B5/14532 , A61B5/6847 , A61B2560/0209 , A61M5/14244 , A61M5/14276 , A61M5/168 , A61M5/16831 , A61M2005/14208 , A61M2205/18 , A61M2205/3507 , A61M2205/3523 , A61M2205/50 , A61M2205/581 , A61M2205/582 , A61M2205/6018 , A61M2205/8206 , A61M2207/00 , A61N1/37211 , A61N1/37247 , A61N1/37252 , A61N1/37258 , A61N1/37264 , A61N1/3727 , A61N1/37276 , A61N1/375 , G06F3/0619 , G06F3/065 , G06F3/0673 , G06F8/60 , G06F8/65 , G06F19/00 , G06F19/3468 , G06Q50/22 , G16H40/40 , Y02D10/42 , Y10S128/13 , Y10S128/903 , Y10T29/49117 , Y10T29/49826
摘要： A communication device (CD) exchanges messages with an implantable infusion pump via telemetry such that commands are supplied thereto and operational information is obtained therefrom. The CD is controlled, at least in part, by a processor IC according to a software program operating therein and provides feedback to a user via a visual display, an audio alarm, and a vibrational alarm, and allows input from the user via a touch sensitive keypad. Certain input functions are restricted by password. The visual display includes an icon and fixed element display region and a bitmap display region. The fixed element display region includes time and date displays, battery and drug level displays that decrement, and a moving delivery state display. Various screens allow operational or log information to be displayed and/or user entry of commands. Program features when disabled are removed from a series of screen options that can be scrolled through.
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3.发明申请公开(公告)号：US20080234638A1
公开(公告)日：2008-09-25
申请号：US12054251
申请日：2008-03-24
CPC分类号： A61M5/14216 , A61M5/14276 , A61M39/22 , A61M2205/0222 , A61M2207/00 , Y10T29/49826
摘要： Valves, valved fluid transfer devices and ambulatory infusion devices including the same.
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公开(公告)号：US08002747B2
公开(公告)日：2011-08-23
申请号：US11420641
申请日：2006-05-26
申请人： Peter C. Lord , Stephen D. Das , Scott R. Gibson
发明人： Peter C. Lord , Stephen D. Das , Scott R. Gibson
IPC分类号： A61M37/00
CPC分类号： A61M5/14276 , A61M5/16827
摘要： An implantable infusion system includes at least two controllable fluid transfer devices that may be used to transfer different fluid flows to the same or different body sites.
摘要翻译： 可植入输注系统包括至少两个可控流体输送装置，其可用于将不同流体流转移到相同或不同的身体部位。
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公开(公告)号：US20110270233A1
公开(公告)日：2011-11-03
申请号：US13182412
申请日：2011-07-13
申请人： Peter C. Lord , Stephen D. Das , Scott R. Gibson
发明人： Peter C. Lord , Stephen D. Das , Scott R. Gibson
IPC分类号： A61M5/142
CPC分类号： A61M5/14276 , A61M5/16827
摘要： An implantable infusion system includes at least two controllable fluid transfer devices that may be used to transfer different fluid flows to the same or different body sites.
摘要翻译： 可植入输注系统包括至少两个可控流体输送装置，其可用于将不同流体流转移到相同或不同的身体部位。
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公开(公告)号：US08808243B2
公开(公告)日：2014-08-19
申请号：US13182412
申请日：2011-07-13
申请人： Peter C. Lord , Stephen D. Das , Scott R. Gibson
发明人： Peter C. Lord , Stephen D. Das , Scott R. Gibson
CPC分类号： A61M5/14276 , A61M5/16827
摘要： An implantable infusion system includes at least two controllable fluid transfer devices that may be used to transfer different fluid flows to the same or different body sites.
摘要翻译： 可植入输注系统包括至少两个可控流体输送装置，其可用于将不同流体流转移到相同或不同的身体部位。
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7.发明授权Valves, valved fluid transfer devices and ambulatory infusion devices including the same 有权阀，阀门流体输送装置和包括其的流动输液装置公开(公告)号：US08251960B2
公开(公告)日：2012-08-28
申请号：US12054009
申请日：2008-03-24
IPC分类号： A61M5/00
CPC分类号： A61M5/16881 , A61M5/14216 , A61M5/14276 , A61M5/16804 , A61M5/16813 , A61M39/22 , A61M39/24 , A61M2039/226 , A61M2205/0216 , A61M2205/0222 , A61M2205/18 , A61M2205/3317 , A61M2205/3331 , A61M2205/50 , A61M2205/52 , A61M2205/75 , A61M2205/8206 , F16K1/32
摘要： Valves, valved fluid transfer devices and ambulatory infusion devices including the same. The valves includes a valve element and a valve seat, and one of the valve seat and the valve element includes a main portion and a seal portion that is less tacky than the main portion.
摘要翻译： 阀，阀门流体输送装置和包括其的流动输液装置。 阀包括阀元件和阀座，阀座和阀元件中的一个包括主体部分和密封部分，该密封部分比主要部分具有较小的粘性。
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公开(公告)号：US07875008B2
公开(公告)日：2011-01-25
申请号：US10924519
申请日：2004-08-23
申请人： Colin Chong , Keith Oberg , Paul Mounce , Peter C. Lord , William P. Van Antwerp
发明人： Colin Chong , Keith Oberg , Paul Mounce , Peter C. Lord , William P. Van Antwerp
CPC分类号： A61M25/0068 , A61L29/085 , A61L29/103 , A61M5/14276 , A61M25/005 , A61M2025/0073 , A61M2025/0076
摘要： A catheter for use in delivery or withdrawal of a formulation, wherein the catheter has an outer layer comprising a bio-compatible material and a barrier layer comprising a material that provides a more effective barrier than the outer layer against inward and outward diffusion of substances that may cause destabilization of the formulation. The catheter may include a flared distal end tip to aid in the release, during a bolus delivery or catheter flush, of any obstruction situated at the distal end tip of the catheter. The catheter may also include a slit valve at the distal end tip which has one or more and, preferably a plurality of slits that may be elastically extended to an open position by the expulsion of the formulation during an IIP pump stroke. During the interval between IIP pump strokes, the slits return to a closed position and hinder the inflow of body fluid into the distal end tip.
摘要翻译： 一种用于递送或取出制剂的导管，其中所述导管具有包含生物相容性材料的外层和阻挡层，所述阻挡层包含提供比所述外层更有效的屏障的材料，以抵抗物质的向内和向外扩散 可能导致制剂不稳定。 导管可以包括扩张的远端尖端，以帮助在推送或导管冲洗期间释放位于导管的远端尖端处的任何阻塞物。 导管还可以包括在远端尖端处的狭缝阀，其具有一个或多个且优选多个狭缝，其可以在IIP泵冲程期间通过排出制剂而弹性地延伸到打开位置。 在IIP泵冲程间隔期间，狭缝返回到关闭位置并阻止体液流入远端尖端。
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9.发明申请Valves, Valved Fluid Transfer Devices and Ambulatory Infusion Devices Including The Same 有权阀门，阀门流体输送装置和包括其的流动输液装置公开(公告)号：US20080234637A1
公开(公告)日：2008-09-25
申请号：US12054009
申请日：2008-03-24
IPC分类号： A61M5/00
CPC分类号： A61M5/16881 , A61M5/14216 , A61M5/14276 , A61M5/16804 , A61M5/16813 , A61M39/22 , A61M39/24 , A61M2039/226 , A61M2205/0216 , A61M2205/0222 , A61M2205/18 , A61M2205/3317 , A61M2205/3331 , A61M2205/50 , A61M2205/52 , A61M2205/75 , A61M2205/8206 , F16K1/32
摘要： Valves, valved fluid transfer devices and ambulatory infusion devices including the same.
摘要翻译： 阀，阀门流体输送装置和包括其的流动输液装置。
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公开(公告)号：US5665065A
公开(公告)日：1997-09-09
申请号：US452406
申请日：1995-05-26
申请人： Fredric C. Colman , Peter C. Lord
发明人： Fredric C. Colman , Peter C. Lord
CPC分类号： A61M5/14244 , A61M5/1723
摘要： A medication infusion device such as a programmable infusion pump includes data input regarding a selected patient parameter such as a current blood glucose reading. The infusion device includes a controller responsive to this data input to develop a medication delivery protocol which can be implemented automatically, recommended via a display for subsequent approval or rejection upon manipulation of control switches, or otherwise overridden in favor of a different medication delivery protocol.
摘要翻译： 诸如可编程输注泵的药物输注装置包括关于所选择的患者参数（例如当前血糖读数）的数据输入。 输注装置包括响应于该数据输入的控制器，用于开发可以自动实现的药物输送方案，通过显示器推荐，以便在控制开关操作时进行随后的批准或拒绝，或以其他方式重写而不同于不同的药物输送方案。
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