公开(公告)号：US20050027245A1

公开(公告)日：2005-02-03

申请号：US10923918

申请日：2004-08-23

申请人： Rohit Sachdeva ,  Petrus Besselink

发明人： Rohit Sachdeva ,  Petrus Besselink

IPC分类号： A61B1/12 ,  A61B17/00 ,  A61B17/122 ,  A61B17/128 ,  A61B17/22 ,  A61B19/00 ,  A61F2/00 ,  A61F2/82 ,  A61M25/00 ,  A61M25/01 ,  A61M25/16 ,  A61M29/00 ,  A61M31/00

CPC分类号： A61B17/32056 ,  A61B1/00082 ,  A61B1/0058 ,  A61B1/015 ,  A61B1/018 ,  A61B1/307 ,  A61B1/3137 ,  A61B5/0084 ,  A61B5/1076 ,  A61B5/6853 ,  A61B17/122 ,  A61B17/1285 ,  A61B17/221 ,  A61B2017/00349 ,  A61B2017/00867 ,  A61B2017/00986 ,  A61B2017/2212 ,  A61B2017/2215 ,  A61B2090/061 ,  A61B2090/063 ,  A61F2/82 ,  A61F2002/30095 ,  A61F2210/0023 ,  A61M25/0013 ,  A61M25/0138 ,  A61M25/0158 ,  A61M25/04 ,  A61M25/09 ,  A61M29/02 ,  A61M2025/0057

摘要： A series of medical instruments can be made with the use of shape memory tube with a transformation temperature that is above or below the ambient temperature. In the first case, the material behaves with the shape memory effect and in the second case the behavior is superelastic. The wall of the tube has been provided with a plurality of slots in specific places, often near or at the distal end of the instrument, and in specific arrangements which allow local variations in diameter, shape, and/or length. These variations can either be caused by the memory effect during temperature change or by superelastic behavior during change of the mechanical influences on the memory metal by the surrounding material.

摘要翻译： 可以使用具有高于或低于环境温度的转换温度的形状记忆管来制造一系列医疗器械。 在第一种情况下，材料表现为形状记忆效应，而在第二种情况下，行为是超弹性的。 管的壁在特定位置经常在仪器的近端或远端设置有多个槽，并且具有允许直径，形状和/或长度的局部变化的特定布置。 这些变化可以由温度变化期间的记忆效应引起，也可以由周围材料对存储金属的机械影响的改变期间的超弹性行为引起。

公开(公告)号：US20060015136A1

公开(公告)日：2006-01-19

申请号：US10528044

申请日：2003-09-18

申请人： Petrus Besselink

发明人： Petrus Besselink

IPC分类号： A61M29/00

CPC分类号： A61F2/013 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/005 ,  A61F2230/0067 ,  A61F2230/0076 ,  A61F2230/008 ,  A61F2230/0093

摘要： A medical device including a fiber-reinforced membrane. The fibers can be embedded into or attached to the membrane to strengthen the device. In one embodiment, the device can be a vascular filter that is attached to an expandable frame. In one device fabrication approach, the device can be made by building it up around a mold. In addition, the mold can be coated with an intermediate material that is easily separated from the membrane material. The intermediate material is covered with the membrane material, after which the fibers are placed in contact with the membrane material that covers the intermediate material. The fibers can then be covered with additional membrane material to embed the fibers into the membrane, after which the mold may be removed by melting, dissolving, deforming or related techniques. Similarly, the intermediate material can be removed from the membrane.

摘要翻译： 包括纤维增强膜的医疗装置。 纤维可以嵌入或附着到膜上以加强装置。 在一个实施例中，该装置可以是连接到可扩展框架的血管过滤器。 在一种器件制造方法中，可以通过在模具周围构建器件来制造器件。 此外，模具可以涂覆有容易与膜材料分离的中间材料。 中间材料被膜材料覆盖，然后使纤维与覆盖中间材料的膜材料接触。 然后可以用另外的膜材料覆盖纤维以将纤维嵌入膜中，之后可以通过熔化，溶解，变形或相关技术除去模具。 类似地，可以从膜去除中间材料。

公开(公告)号：US20050113862A1

公开(公告)日：2005-05-26

申请号：US10974539

申请日：2004-10-27

申请人： Petrus Besselink ,  Hans Hanssen ,  Wouter Markus

发明人： Petrus Besselink ,  Hans Hanssen ,  Wouter Markus

IPC分类号： A61F2/01 ,  A61F2/06 ,  A61F2/84 ,  A61M25/00 ,  A61M25/01 ,  A61M25/04 ,  A61M25/09 ,  A61M29/00 ,  A61M29/02

CPC分类号： A61M29/02 ,  A61B17/221 ,  A61B2017/003 ,  A61B2017/0046 ,  A61B2017/22047 ,  A61F2/013 ,  A61F2/95 ,  A61F2002/011 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/0067 ,  A61M25/0138 ,  A61M25/0147 ,  A61M25/04 ,  A61M25/09 ,  A61M25/09025 ,  A61M2025/0681 ,  A61M2025/09141

摘要： An improved endoluminal device. The device includes at least a control element (such as a guide wire) connected to a surrounding sheath and an elastic bias section to control changes to a bias force formed between the control element and the sheath. By applying an external force at a proximal end of the device, the shape can change between varying degrees of deformed shapes and an undeformed shape. In this way, both ease of insertion into the body lumen and anchoring to the lumen is promoted. A distal end of the assembly can be made to change shape for improved steerability, anchoring or both. In a particular form, the anchoring section can work as a floating parachute-like device to pull the assembly by means of the flow in the body lumen, while in a more particular form, the floating parachute-like device may be modified to act as a filter for trapping emboli.

摘要翻译： 改进的腔内装置。 该装置至少包括连接到周围护套的控制元件（例如导丝）和弹性偏置部分，以控制对控制元件和护套之间形成的偏压力的变化。 通过在装置的近端施加外力，形状可以在不同程度的变形形状和未变形的形状之间变化。 以这种方式，促进插入体腔的容易性和锚固到内腔。 可以使组件的远端改变形状以改善操纵性，锚固性或两者。 在特定形式中，锚定部分可以作为浮动的降落伞状装置工作，以通过体腔中的流动来拉动组件，而在更具体的形式中，浮动式降落伞状装置可以被修改为充当 用于捕获栓塞的过滤器。

公开(公告)号：US20060241739A1

公开(公告)日：2006-10-26

申请号：US11317495

申请日：2005-12-22

申请人： Petrus Besselink ,  Travis Yribarren ,  Randolf Von Oepen

发明人： Petrus Besselink ,  Travis Yribarren ,  Randolf Von Oepen

IPC分类号： A61F2/06

CPC分类号： A61B17/11 ,  A61F2/0009 ,  A61F2/064 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/30062 ,  A61F2002/828 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2002/91575 ,  A61F2210/0004 ,  A61F2230/0013 ,  B23K2103/42 ,  B23K2103/50 ,  B33Y80/00

摘要： Expandable biodegradable devices formed of bistable and multistable unit cells for use in devices, such as stents and graft systems, are provided, in which the device has two or more stable configurations, including a contracted configuration and an expanded configuration, the contracted stable configuration having a smaller diameter than the expanded configuration.

摘要翻译： 提供了用于诸如支架和移植物系统的装置中的双稳态和多单元电池形成的可膨胀的可生物降解的装置，其中装置具有两个或多个稳定的构造，包括收缩构型和扩张构型，收缩的稳定构型具有 直径比扩张结构小。

公开(公告)号：US20060217795A1

公开(公告)日：2006-09-28

申请号：US11391940

申请日：2006-03-29

申请人： Petrus Besselink ,  Mark Bates

发明人： Petrus Besselink ,  Mark Bates

IPC分类号： A61F2/06

CPC分类号： A61F2/88 ,  A61B17/11 ,  A61F2/064 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91541

摘要： Vascular prostheses and methods of use are provided, wherein the vascular prosthesis includes a plurality of bistable unit cells configured to form a helical structure. A visualization catheter also is provided for use ensuring accurate measurement of a lesion and ensuring delivery and placement of the vascular prosthesis.

公开(公告)号：US20060206136A1

公开(公告)日：2006-09-14

申请号：US11381217

申请日：2006-05-02

申请人： Rohit Sachdeva ,  Petrus Besselink

发明人： Rohit Sachdeva ,  Petrus Besselink

IPC分类号： A61M29/00

CPC分类号： A61B17/32056 ,  A61B1/00082 ,  A61B1/0058 ,  A61B1/015 ,  A61B1/018 ,  A61B1/307 ,  A61B1/3137 ,  A61B5/0084 ,  A61B5/1076 ,  A61B5/6853 ,  A61B17/122 ,  A61B17/1285 ,  A61B17/221 ,  A61B2017/00349 ,  A61B2017/00867 ,  A61B2017/00986 ,  A61B2017/2212 ,  A61B2017/2215 ,  A61B2090/061 ,  A61B2090/063 ,  A61F2/82 ,  A61F2002/30095 ,  A61F2210/0023 ,  A61M25/0013 ,  A61M25/0138 ,  A61M25/0158 ,  A61M25/04 ,  A61M25/09 ,  A61M29/02 ,  A61M2025/0057

摘要： A series of medical instruments can be made with the use of shape memory tube with a transformation temperature that is above or below the ambient temperature. In the first case, the material behaves with the shape memory effect and in the second case the behavior is superelastic. The wall of the tube has been provided with a plurality of slots in specific places, often near or at the distal end of the instrument, and in specific arrangements which allow local variations in diameter, shape, and/or length. These variations can either be caused by the memory effect during temperature change or by superelastic behavior during change of the mechanical influences on the memory metal by the surrounding material.

摘要翻译： 可以使用具有高于或低于环境温度的转换温度的形状记忆管来制造一系列医疗器械。 在第一种情况下，材料表现为形状记忆效应，而在第二种情况下，行为是超弹性的。 管的壁在特定位置经常在仪器的近端或远端设置有多个槽，并且具有允许直径，形状和/或长度的局部变化的特定布置。 这些变化可以由温度变化期间的记忆效应引起，也可以由周围材料对存储金属的机械影响的改变期间的超弹性行为引起。

公开(公告)号：US20060155360A1

公开(公告)日：2006-07-13

申请号：US10523959

申请日：2003-07-29

申请人： Jorge Calisse ,  Petrus Besselink

发明人： Jorge Calisse ,  Petrus Besselink

IPC分类号： A61F2/06

CPC分类号： A61F2/82 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91541 ,  A61F2002/9155 ,  A61F2002/91558 ,  A61F2002/91566 ,  A61F2250/0018

摘要： A stent is described comprising a unit cell having a negative spring rate and a bistable function. The unit cell comprises first and second segments, the first segment being more rigid than the second segment. The second segment is coupled to the first segment, and the first segment comprises a substantially fixed sinusoidal shape. In the contracted state, the second segment is held stable in a sinusoidal shape, but when a force is applied the second segment bends out to a stable, convex-shaped deployed state. The second segments withstand the application of radial forces in the convex-shaped deployed state, and diametral recoil of the stent is minimized.

摘要翻译： 描述了一种支架，其包括具有负弹簧刚度和双稳态功能的单电池。 单元电池包括第一和第二段，第一段比第二段更刚性。 第二段联接到第一段，并且第一段包括基本上固定的正弦形状。 在收缩状态下，第二段以正弦形状保持稳定，但是当施加力时，第二段弯曲成稳定的凸形展开状态。 第二部分承受在凸形展开状态下的径向力的应用，并且使支架的直径反冲最小化。

公开(公告)号：US06669718B2

公开(公告)日：2003-12-30

申请号：US09908446

申请日：2001-07-18

申请人： Petrus Besselink

发明人： Petrus Besselink

IPC分类号： A61F206

CPC分类号： A61F2/954 ,  A61F2/86 ,  A61F2/958 ,  A61F2002/065 ,  A61F2002/067 ,  A61M2025/1065

摘要： An apparatus and method to place a bifurcated stent into a body lumen by using a delivery device requiring only one incision. Relative axial movements between a catheter and a sheath in the delivery device permit the insertion and expansion of the stent. During placement into and removal from the patient's body, the branch sections of the bifurcated stent are held in substantially parallel arrangement. Opposing tendencies between a self-expanding stent and leg portions within the delivery device can be tailored such that, during deployment, the bifurcation bias due to the elastic spring forces in the stent overcome the parallel bias within the delivery device. In situations where a balloon-expandable stent is used, the delivery device obviates the need for balloon change during stent placement. Such catheters can also be used for angioplasty, eventually in combination with stenting, and are also equally applicable to both multibranch and side branch body lumens, which are difficult to reach with conventional devices and techniques.

公开(公告)号：US06488710B2

公开(公告)日：2002-12-03

申请号：US09797927

申请日：2001-03-02

申请人： Petrus Besselink

发明人： Petrus Besselink

IPC分类号： A61F244

CPC分类号： A61F2/4455 ,  A61F2/442 ,  A61F2/4611 ,  A61F2002/30093 ,  A61F2002/30098 ,  A61F2002/301 ,  A61F2002/30102 ,  A61F2002/30153 ,  A61F2002/30179 ,  A61F2002/30271 ,  A61F2002/30283 ,  A61F2002/30293 ,  A61F2002/30476 ,  A61F2002/30579 ,  A61F2002/30594 ,  A61F2002/30596 ,  A61F2002/30624 ,  A61F2002/30626 ,  A61F2002/30975 ,  A61F2002/444 ,  A61F2002/4475 ,  A61F2002/4627 ,  A61F2002/4635 ,  A61F2210/0019 ,  A61F2210/0033 ,  A61F2210/0038 ,  A61F2210/0042 ,  A61F2220/0025 ,  A61F2230/0019 ,  A61F2230/0058 ,  A61F2230/0063 ,  A61F2230/0082 ,  A61F2230/0091 ,  A61F2310/00011

摘要： An expandable inter-vertebral prosthesis. The prosthesis takes over the supporting function of the inter-vertebra disc between two adjacent vertebra bodies, and includes one or more cages and a reinforcing element. Upon cage expansion, a hollow central portion of the cage can accommodate the reinforcing element. The reinforcing element, upon expansion, assumes a spiral shape, and substantially fills up the hollow central portion of the cage to provide enhanced load-bearing capability in a substantially longitudinal spinal direction. Hinges in the cage permit expansion and, once the cage has expanded, prevent it from collapsing. Delivery of the cage in an unexpanded condition into an inter-vertebral space is ensured with a restraining tool that engages the hinge members. The cage, reinforcing element and restraining tool are inserted with the aid of a conventional delivery tube.

摘要翻译： 可扩展的椎间假体。 假体在两个相邻的椎骨体之间占据脊椎椎间盘的支撑功能，并且包括一个或多个笼和加强元件。 在笼笼膨胀时，保持架的中空中心部分可容纳加强元件。 增强元件在膨胀时呈现螺旋形状，并且基本上填充保持架的中空中心部分以在基本上纵向的脊柱方向上提供增强的承载能力。 笼中的铰链允许扩张，一旦笼子扩张，防止它塌陷。 使用与铰链构件接合的限制工具来确保将笼子以未膨胀的状态递送到椎间空间。 笼，加强元件和约束工具借助于常规输送管插入。