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    Planar resonant tunneling sensor and method of fabricating and using the same
    1.
    发明授权
    Planar resonant tunneling sensor and method of fabricating and using the same 失效
    平面谐振隧道传感器及其制造和使用方法

    公开(公告)号：US07114378B1

    公开(公告)日：2006-10-03

    申请号：US11107996

    申请日：2005-04-14

    申请人： Philip W. Barth ,  Derek Stein ,  Curt Flory ,  Rick Pittaro ,  Daniel Roitman

    发明人： Philip W. Barth ,  Derek Stein ,  Curt Flory ,  Rick Pittaro ,  Daniel Roitman

    IPC分类号： G01B5/28

    CPC分类号： G01Q30/02 ,  G01N15/1031

    摘要： Planar resonant tunneling sensor devices and methods for using the same are provided. The subject devices include first and second electrodes present on a surface of a planar substrate and separated from each other by a nanodimensioned gap. The devices also include a first member for holding a sample, and a second member for moving the first member and planar resonant tunneling electrode relative to each other. Also provided are methods of fabricating such a device and methods of using such a device for improved detection and characterization of a sample.

    摘要翻译： 提供了平面谐振隧道传感器装置及其使用方法。 本装置包括存在于平面基板的表面上的第一和第二电极，并通过纳米尺寸的间隙彼此分离。 这些装置还包括用于保持样品的第一构件和用于相对于彼此移动第一构件和平面谐振隧穿电极的第二构件。 还提供了制造这种装置的方法和使用这种装置来改进样品的检测和表征的方法。

    PLANAR RESONANT TUNNELING SENSOR AND METHOD OF FABRICATING AND USING THE SAME
    2.
    发明申请
    PLANAR RESONANT TUNNELING SENSOR AND METHOD OF FABRICATING AND USING THE SAME 失效
    平面谐振隧道传感器及其制造和使用方法

    公开(公告)号：US20060230818A1

    公开(公告)日：2006-10-19

    申请号：US11107996

    申请日：2005-04-14

    申请人： Phillip Barth ,  Derek Stein ,  Curt Flory ,  Rick Pittaro ,  Daniel Roitman

    发明人： Phillip Barth ,  Derek Stein ,  Curt Flory ,  Rick Pittaro ,  Daniel Roitman

    IPC分类号： H01L31/072

    CPC分类号： G01Q30/02 ,  G01N15/1031

    摘要： Planar resonant tunneling sensor devices and methods for using the same are provided. The subject devices include first and second electrodes present on a surface of a planar substrate and separated from each other by a nanodimensioned gap. The devices also include a first member for holding a sample, and a second member for moving the first member and planar resonant tunneling electrode relative to each other. Also provided are methods of fabricating such a device and methods of using such a device for improved detection and characterization of a sample.

    摘要翻译： 提供了平面谐振隧道传感器装置及其使用方法。 本装置包括存在于平面基板表面上的第一和第二电极，并通过纳米尺寸的间隙彼此分离。 这些装置还包括用于保持样品的第一构件和用于相对于彼此移动第一构件和平面谐振隧穿电极的第二构件。 还提供了制造这种装置的方法和使用这种装置来改进样品的检测和表征的方法。

    Evanescent wave sensor with attached ligand
    6.
    发明申请
    Evanescent wave sensor with attached ligand 审中-公开
    具有附着配体的渐逝波传感器

    公开(公告)号：US20070099180A1

    公开(公告)日：2007-05-03

    申请号：US11264808

    申请日：2005-10-31

    申请人： Karla Robotti ,  Daniel Roitman

    发明人： Karla Robotti ,  Daniel Roitman

    IPC分类号： C12Q1/70 ,  G01N33/554 ,  C12M1/34

    CPC分类号： G01N33/54373 ,  B82Y15/00 ,  B82Y30/00 ,  G01N21/553 ,  G01N33/54353

    摘要： The invention in particular embodiments provides an evanescent wave sensor which includes a ligand bound to a sensor substrate via a β-hydroxy-linker moiety, as defined herein. Methods of making the subject evanescent wave sensors are also provided which include contacting a first reactive moiety which has an epoxy-ring moiety with a second reactive moiety which has an amino moiety or a thiol moiety, as further described herein. Also provided by the invention are methods in which a subject evanescent wave sensor is contacted with a sample, and binding of analytes in the sample to the sensor is assessed by evanescent wave detection. The invention also provides kits and systems for performing the subject methods.

    摘要翻译： 本发明在具体实施方案中提供了一种ev逝波传感器，其包括通过本文定义的β-羟基 - 连接体部分与传感器底物结合的配体。 还提供了制备对象ev逝波传感器的方法，其包括使具有环氧环部分的第一反应性部分与具有氨基部分或硫醇部分的第二反应性部分接触，如本文进一步描述的。 本发明还提供了一种方法，其中对象ev逝波传感器与样品接触，并且通过ev逝波检测来评估样品中的分析物与传感器的结合。 本发明还提供用于执行主题方法的套件和系统。

    Integrated opto-electric SPR sensor
    7.
    发明申请
    Integrated opto-electric SPR sensor 审中-公开
    集成光电SPR传感器

    公开(公告)号：US20070052049A1

    公开(公告)日：2007-03-08

    申请号：US11222206

    申请日：2005-09-07

    申请人： Sandeep Bahl ,  Daniel Roitman

    发明人： Sandeep Bahl ,  Daniel Roitman

    IPC分类号： H01L27/14

    CPC分类号： G01N21/553 ,  G01N21/253

    摘要： An integrated opto-electric sensor includes a wavenumber matching structure that is integrated onto a silicon substrate, and a first conductive electrode that is adjacent to one of a lightly doped and an undoped region in the silicon substrate to form a Schottky junction. A dielectric is positioned adjacent to the first conductive electrode, and a second conductive electrode is formed at the silicon substrate. The first conductive electrode and the second conductive electrode provide coupling for a detected signal that is provided in response to illumination of the wavenumber matching structure by an optical signal.

    摘要翻译： 集成光电传感器包括集成在硅衬底上的波数匹配结构和与硅衬底中的轻掺杂区域和未掺杂区域中的一个相邻的第一导电电极，以形成肖特基结。 电介质位于与第一导电电极相邻的位置处，在硅衬底上形成第二导电电极。 第一导电电极和第二导电电极为通过光信号响应于波数匹配结构的照明而提供的检测信号提供耦合。

    Optical phase measurement of target
    8.
    发明申请
    Optical phase measurement of target 有权
    目标光学相位测量

    公开(公告)号：US20050194523A1

    公开(公告)日：2005-09-08

    申请号：US10795917

    申请日：2004-03-08

    申请人： Gregory VanWiggeren ,  Daniel Roitman

    发明人： Gregory VanWiggeren ,  Daniel Roitman

    IPC分类号： G01N21/21 ,  G01J9/00 ,  G01N21/27 ,  G01N21/39 ,  G01N21/55 ,  G02B6/00

    CPC分类号： G01J9/00 ,  G01N21/553

    摘要： Optical phase detection includes generating a first lightwave having a first polarization and a second lightwave having a polarization that is offset from the first polarization, and imposing a relative delay between the first and second lightwaves. The relative delay causes a frequency offset between the lightwaves as wavelength is tuned over a designated wavelength range. Directing the first and second lightwaves to a target provides a third lightwave and a fourth lightwave. A polarization component of the third lightwave and a polarization component of the fourth lightwave are detected to provide a detected signal at the frequency offset. The optical phase detection then includes extracting a phase difference, induced by the target, between the polarization components of the third and the fourth lightwaves.

    摘要翻译： 光相位检测包括产生具有第一偏振的第一光波和具有偏离第一偏振的偏振的第二光波，并且在第一和第二光波之间施加相对延迟。 当波长在指定的波长范围内调谐时，相对延迟会导致光波之间的频率偏移。 将第一和第二光波导向目标提供第三光波和第四光波。 检测第三光波的偏振分量和第四光波的偏振分量，以提供频偏处的检测信号。 然后，光学相位检测包括在第三和第四光波的偏振分量之间提取由目标感应的相位差。