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    INFRARED CAMERA CALIBRATION TECHNIQUES
    4.
    发明申请
    INFRARED CAMERA CALIBRATION TECHNIQUES 有权
    红外相机校准技术

    公开(公告)号：US20120312976A1

    公开(公告)日：2012-12-13

    申请号：US13491428

    申请日：2012-06-07

    申请人： Pierre Boulanger ,  Theodore R. Hoelter ,  Barbara Sharp ,  Eric A. Kurth

    发明人： Pierre Boulanger ,  Theodore R. Hoelter ,  Barbara Sharp ,  Eric A. Kurth

    IPC分类号： H01L27/146

    CPC分类号： H04N5/33 ,  G01J5/00 ,  G01J5/02 ,  G01J5/20 ,  G01J5/522 ,  H04N5/2257 ,  H04N5/2351 ,  H04N5/2354 ,  H04N5/332 ,  H04N7/18

    摘要： Various techniques are disclosed for testing and/or calibrating infrared imaging modules. For example, a method of calibrating an infrared imaging module may include providing a plurality of temperature controlled environments. The method may also include transporting the infrared imaging module through the environments. The method may also include performing a measurement in each environment using an infrared sensor assembly of the infrared imaging module and determining a plurality of calibration values for the infrared imaging module based on the measurements.

    摘要翻译： 公开了用于测试和/或校准红外成像模块的各种技术。 例如，校准红外成像模块的方法可以包括提供多个受温度控制的环境。 该方法还可以包括通过环境传输红外成像模块。 该方法还可以包括使用红外成像模块的红外传感器组件在每个环境中执行测量，并且基于测量来确定红外成像模块的多个校准值。

    Use of a polypeptide as cell receptor for adenoviruses
    9.
    发明授权
    Use of a polypeptide as cell receptor for adenoviruses 失效
    使用多肽作为腺病毒的细胞受体

    公开(公告)号：US06420120B1

    公开(公告)日：2002-07-16

    申请号：US09155613

    申请日：1998-09-30

    申请人： Pierre Boulanger ,  Saw See Hong ,  Lucie Karayan

    发明人： Pierre Boulanger ,  Saw See Hong ,  Lucie Karayan

    IPC分类号： G01N3353

    CPC分类号： C12N15/86 ,  A61K38/00 ,  A61K48/00 ,  C07K14/70539 ,  C07K14/78 ,  C07K2319/00 ,  C12N2710/10343 ,  C12N2710/10345 ,  C12N2810/40 ,  C12N2810/80 ,  C12N2810/859 ,  C12N2830/00 ,  C12N2830/60

    摘要： The subject of the present invention is the use of a polypeptide comprising at least 6 continuous amino acids of the sequence as shown in the sequence identifiers 1 to 5 as cellular receptor and/or coreceptor for adenoviruses. It also relates to the use of a cell capable of expressing such a polypeptide as well as that of a ligand capable of influencing the attachment of an adenovirus to a host cell and/or its entry into the said host cell. Finally, it also relates to a method for selecting or identifying a cellular receptor for a virus or the part of a viral protein which determines the attachment of the virus to its cellular receptor as well as to the use of a bifunctional ligand to target an adenovirus to a host cell carrying, at its surface, a surface protein other than the natural cellular receptor for the said adenovirus.

    摘要翻译： 本发明的主题是包含序列标识符1至5中所示的序列的至少6个连续氨基酸的多肽作为腺病毒的细胞受体和/或共受体的用途。 它还涉及能够表达这种多肽的细胞以及能够影响腺病毒与宿主细胞的连接和/或其进入所述宿主细胞的配体的细胞的使用。 最后，它还涉及用于选择或鉴定病毒的细胞受体或确定病毒与其细胞受体的连接的病毒蛋白的部分的方法，以及使用双功能配体靶向腺病毒 涉及在其表面上携带除所述腺病毒的天然细胞受体之外的表面蛋白质的宿主细胞。

    Derivatives of 3-O-(3',3'-dimethylsuccinyl)-betulinic acid
    10.
    发明授权
    Derivatives of 3-O-(3',3'-dimethylsuccinyl)-betulinic acid 有权
    3-O-（3'，3'-二甲基琥珀酰基） - 丁酰酸的衍生物

    公开(公告)号：US09056888B2

    公开(公告)日：2015-06-16

    申请号：US13608486

    申请日：2012-09-10

    申请人： Serge Bouaziz ,  Pascale Coric ,  Pierre Boulanger ,  Saw-See Hong ,  Serge Turcaud ,  Florence Souquet ,  Nathalie Chazal ,  Laurence Briant

    发明人： Serge Bouaziz ,  Pascale Coric ,  Pierre Boulanger ,  Saw-See Hong ,  Serge Turcaud ,  Florence Souquet ,  Nathalie Chazal ,  Laurence Briant

    IPC分类号： A61K31/56 ,  C07J53/00 ,  C07J63/00

    CPC分类号： C07J53/002 ,  C07J63/008

    摘要： The present invention relates to compounds of the following formula (I): or a pharmaceutically acceptable salt thereof, a stereoisomer or a mixture of stereoisomers in any proportion, in particular a mixture of enantiomers, and particularly a racemate mixture, in which R represents a (C1-C10)alkyl group substituted with one or more, preferably one or two, groups chosen from COOH and NHR1, with R1 representing a hydrogen atom or a -Alk, —C(O)-Alk or —C(O)O-Alk group, Alk representing a (C1-C6)alkyl group, as well as a method for preparing them, and their use as a medicine, notably for treating an infection with a retrovirus such as HIV.

    摘要翻译： 本发明涉及下列通式（I）的化合物或其药学上可接受的盐，立体异构体或任何比例的立体异构体的混合物，特别是对映异构体的混合物，特别是外消旋物混合物，其中R表示 被一个或多个，优选一个或两个选自COOH和NHR1的基团取代的（C1-C10）烷基，其中R1表示氢原子或-Alk，-C（O）-Alk或-C（O）O -Alk基团，代表（C1-C6）烷基的Alk，以及它们的制备方法，以及它们作为药物的用途，特别是用于治疗HIV等逆转录病毒的感染。