Photodetectors
    2.
    发明申请

    公开(公告)号:US20210111298A1

    公开(公告)日:2021-04-15

    申请号:US17066735

    申请日:2020-10-09

    Abstract: The subject matter of this specification can be embodied in, among other things, a photodetector that includes a semiconductor substrate, a semiconductor annulus on a planar face the semiconductor substrate, and a metal layer on the semiconductor substrate, wherein the metal layer comprises a first region surrounding the semiconductor annulus and comprises a second region filling an interior region to the semiconductor annulus, and the metal layer in the first region forms a Schottky junction with the semiconductor ring.

    Electrodes formed from 2D materials for dielectrophoresis and systems and methods for utilizing the same

    公开(公告)号:US20210220840A1

    公开(公告)日:2021-07-22

    申请号:US17121285

    申请日:2020-12-14

    Abstract: Devices, systems, and methods for applying a dielectrophoretic force on a particle include: a cell defining at least one channel for confining the particle; and a first electrode and a second electrode electrically isolated from the first electrode, at least one of the first and second electrodes being formed from a two-dimensional (2D) material providing an atomically sharp edge. The first and second electrodes are arranged sufficiently close to one another and sufficiently close to the channel such that application of a sufficient voltage across the first and second electrodes generates an electric field in at least part of the channel, the electric field having an electric field gradient sufficient to apply the dielectrophoretic force on the particle in the channel.

    GRAPHENE-BASED DIELECTROPHORESIS SENSOR AND METHOD

    公开(公告)号:US20210245172A1

    公开(公告)日:2021-08-12

    申请号:US16972858

    申请日:2019-06-05

    Abstract: A dielectrophoretic (DEP) sensor includes a graphene electrode adjacent a channel for confining a target particle in a liquid, a surface probe attached to a surface of the graphene electrode, the surface probe having a selective reaction with the target particle, and a voltage source electrically connected to the graphene electrode and configured to apply a voltage to the graphene electrode to cause DEP trapping of the target particle at the graphene electrode.

    Electrodes formed from 2D materials for dielectrophoresis and systems and methods for utilizing the same

    公开(公告)号:US10888875B2

    公开(公告)日:2021-01-12

    申请号:US16010980

    申请日:2018-06-18

    Abstract: Devices, systems, and methods for applying a dielectrophoretic force on a particle include: a cell defining at least one channel for confining the particle; and a first electrode and a second electrode electrically isolated from the first electrode, at least one of the first and second electrodes being formed from a two-dimensional (2D) material providing an atomically sharp edge. The first and second electrodes are arranged sufficiently close to one another and sufficiently close to the channel such that application of a sufficient voltage across the first and second electrodes generates an electric field in at least part of the channel, the electric field having an electric field gradient sufficient to apply the dielectrophoretic force on the particle in the channel.

    METHODS AND MATERIALS FOR DETECTING MISFOLDED POLYPEPTIDES

    公开(公告)号:US20240192229A1

    公开(公告)日:2024-06-13

    申请号:US18286682

    申请日:2022-04-15

    Abstract: This document relates to methods and materials for detecting the presence or absence of misfolded polypeptides in a sample. For example, methods and materials for amplifying a sample (e.g., a biological sample or an environmental sample) such that misfolded polypeptides present in the sample can aggregate to form fibrils and/or globular polypeptide aggregates and contacting the amplified sample with a solution containing metal nanoparticles (e.g., gold nanoparticles) or one or more organic dyes (e.g., Congo Red) to detect the presence or absence of fibrils and/or globular polypeptide aggregates are provided. In some cases, methods and materials for determining if a mammal (e.g., a human) has a proteinopathy based, at least in part, in the presence or absence of misfolded polypeptides in a sample obtained from the mammal are provided.

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