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93 条记录 (耗时 0.052 秒)

    Fourier transform surface plasmon resonance adsorption sensor instrument
    1.
    发明授权
    Fourier transform surface plasmon resonance adsorption sensor instrument 有权
    傅里叶变换表面等离子共振吸收传感器仪器

    公开(公告)号：US06330062B1

    公开(公告)日：2001-12-11

    申请号：US09303260

    申请日：1999-04-30

    申请人： Robert M. Corn ,  Michael J. Green ,  Stephen C. Weibel ,  Tony G. Frutos

    发明人： Robert M. Corn ,  Michael J. Green ,  Stephen C. Weibel ,  Tony G. Frutos

    IPC分类号： G01N2155

    CPC分类号： G01N21/35 ,  G01N21/359 ,  G01N21/553

    摘要： Adsorption of molecules onto a thin metallic surface such as of gold, silver or copper is measured by surface plasmon resonance (SPR) using Fourier Transform (FT) spectroscopy. Reflectance spectra from a prism/metallic film sample surface at a fixed angle of incidence is measured with FT spectroscopy. The reflectance spectrum exhibits a pronounced minimum due to the SPR effect, which can be shifted by changing the angle of incidence or metallic film thickness. The position of the reflectance minimum shifts in wavelength with the adsorption of molecules onto the gold surface due to a change in the index of refraction at the interface. The FT-SPR sensor instrument provides wavelength stability and reproducibility of the resonance wavelength to permit detection of small wavelength shifts, and also substantially increases the spectral range over which the SPR measurements can be made. A beam of broadband radiation from a Michelson interferometer is directed through an SPR sample cell and onto a detector where the output signal is processed using standard FT techniques.

    摘要翻译： 使用傅立叶变换（FT）光谱法，通过表面等离子体共振（SPR）测量分子到金，银或铜等金属表面上的吸附。 用FT光谱法测量来自固定入射角的棱镜/金属膜样品表面的反射光谱。 由于SPR效应，反射光谱显示出明显的最小值，可通过改变入射角或金属膜厚度来移动反射光谱。 由于界面处的折射率的变化，反射率最小值的位置随着分子吸附在金表面上而波长的偏移。 FT-SPR传感器仪器提供了波长稳定性和谐振波长的再现性，以允许检测小的波长位移，并且还大大提高可以进行SPR测量的光谱范围。 来自迈克尔逊干涉仪的宽带辐射波束通过SPR采样单元引导到检测器上，其中使用标准FT技术处理输出信号。

    Panel assembly for a vehicle and a method of supporting the panel assembly
    2.
    发明授权
    Panel assembly for a vehicle and a method of supporting the panel assembly 有权
    用于车辆的面板组件和支撑面板组件的方法

    公开(公告)号：US08523272B1

    公开(公告)日：2013-09-03

    申请号：US13487724

    申请日：2012-06-04

    申请人： James D. Pettus ,  Michael J. Green

    发明人： James D. Pettus ,  Michael J. Green

    IPC分类号： B60N99/00

    CPC分类号： B62D29/002 ,  B62D25/16

    摘要： A panel assembly for a vehicle and a method of supporting the panel assembly is disclosed. The panel assembly includes a first wall and a bracket adjacent to the first wall. The bracket has a first platform facing the first wall. The panel assembly further includes a first support member attached to the first platform and defining an initial state and a final state. The first support member and the first wall define a first gap therebetween when in the initial state. The first support member is expandable to contact the first wall to remove the first gap when in the final state for supporting the first wall to prevent deformation of the first wall.

    摘要翻译： 公开了用于车辆的面板组件和支撑面板组件的方法。 面板组件包括邻近第一壁的第一壁和支架。 支架具有面向第一壁的第一平台。 面板组件还包括附接到第一平台并限定初始状态和最终状态的第一支撑构件。 当处于初始状态时，第一支撑构件和第一壁在其间限定第一间隙。 当处于最终状态以支撑第一壁以防止第一壁变形时，第一支撑构件可膨胀以接触第一壁以移除第一间隙。

    Spa control system
    4.
    发明授权
    Spa control system 失效
    水疗控制系统

    公开(公告)号：US06976052B2

    公开(公告)日：2005-12-13

    申请号：US09761264

    申请日：2001-01-16

    申请人： Michael E. Tompkins ,  Michael J. Green

    发明人： Michael E. Tompkins ,  Michael J. Green

    IPC分类号： A61H33/00 ,  G05D23/20 ,  G06F13/00

    CPC分类号： A61H33/0095 ,  G05D23/1931 ,  G05D23/20

    摘要： An improved spa control system is disclosed. The invention describes a spa control system which calculates the time required to heat the water in the spa system to a desired temperature. From that information, the heating rate of the spa system can be determined, and the heating element of the spa system can be activated at the proper time to raise the temperature of the water to a selected temperature by a desired time. The spa system also monitors information which might show errors in the operation of the spa system such as a blockage in the flow of water over the heating element in the spa system.

    摘要翻译： 公开了一种改进的水疗控制系统。 本发明描述了一种水疗控制系统，其计算将温泉系统中的水加热到所需温度所需的时间。 根据该信息，可以确定水疗系统的加热速率，并且可以在适当的时间激活水疗系统的加热元件，以将水的温度升高到所选温度所需的时间。 水疗系统还监测可能在水疗系统的操作中显示错误的信息，例如在水疗系统中的加热元件上的水流中的堵塞。

    Imidazoylalkyl substituted with a six membered nitrogen containing nitrogen containing heterocyclic ring
    5.
    发明授权
    Imidazoylalkyl substituted with a six membered nitrogen containing nitrogen containing heterocyclic ring 失效
    用含六价氮的含氮杂环取代的咪唑烷基

    公开(公告)号：US5932596A

    公开(公告)日：1999-08-03

    申请号：US457352

    申请日：1995-06-01

    申请人： Neng-Yang Shih ,  Michael J. Green

    发明人： Neng-Yang Shih ,  Michael J. Green

    IPC分类号： C07D401/06 ,  A61K31/445

    CPC分类号： C07D401/06

    摘要： Disclosed is a compound of Formula 1.0: ##STR1## or a pharmaceutically acceptable salt or solvate thereof. Also disclosed are pharmaceutical compositions comprising a pharmaceutically acceptable carrier and an effective amount of a Compound of Formula 1.0.Further disclosed is a method of treating allergy (for example asthma), inflammation, hypertension, raised intraocular pressure (such as glaucoma)--i.e., a method of lowering intraocular pressure, sleeping disorders, states of hyper and hypo motility and acidic secretion of the gastrointestinal tract, hypo and hyperactivity of the central nervous system (for example, agitation and depression) and other CNS disorders (such as Alzheimers, Schizophrenia, and migraine) comprising administering an effective amount of a compound of Formula 1.0 to a patient in need of such treatment.

    摘要翻译： 公开了式1.0的化合物或其药学上可接受的盐或溶剂化物。 还公开了包含药学上可接受的载体和有效量的式1.0化合物的药物组合物。 进一步公开的是治疗过敏（例如哮喘），炎症，高血压，升高的眼内压（例如青光眼）的方法，降低眼内压的方法，睡眠障碍，超低运动性和酸性分泌的状态 胃肠道，中枢神经系统的低血压和多动症（例如，激动和抑郁）和其他CNS疾病（例如阿尔茨海默病，精神分裂症和偏头痛），包括向有需要的患者施用有效量的式1.0化合物 这样的治疗。

    Benzopyrido piperidylidene compounds, compositions, methods of manufacture and methods of use
    6.
    发明授权
    Benzopyrido piperidylidene compounds, compositions, methods of manufacture and methods of use 失效
    苯并吡啶哌啶基化合物，组合物，制造方法和使用方法

    公开(公告)号：US5430032A

    公开(公告)日：1995-07-04

    申请号：US185784

    申请日：1994-01-21

    申请人： Jesse K. Wong ,  John J. Piwinski ,  Michael J. Green

    发明人： Jesse K. Wong ,  John J. Piwinski ,  Michael J. Green

    IPC分类号： A61K31/445 ,  A61K31/495 ,  A61P11/00 ,  A61P29/00 ,  A61P37/08 ,  C07D491/04 ,  C07D491/044 ,  C07D495/04 ,  A61K31/44 ,  C07D401/00 ,  C07D491/02

    CPC分类号： C07D491/04 ,  C07D495/04

    摘要： Disclosed is a compound of Formula I: ##STR1## or a pharmaceutically acceptable salt or solvate thereof, wherein: R is selected from the group consisting of: H, Cl, Br, F, and I; T represents C or N with the dotted line attached to T representing a double bond when T is C and being absent when T is N; and X represents O or S with the proviso that T is N when X is O.Also disclosed is a pharmaceutical composition comprising a compound of Formula I and a pharmaceutically acceptable carrier.Further disclosed is a method of treating asthma, allergy and/or inflammation comprising administering to a mammal in need of such treatment an anti-asthmatic, anti-allergic and/or an anti-inflammatory, respectively, effective amount of a compound of Formula I.

    摘要翻译： 公开了式I的化合物：其中：R选自：H，Cl，Br，F和I;或其药学上可接受的盐或溶剂合物。 T表示C或N，当T为C时，虚线与T表示双键，当T为N时，不存在; 并且X表示O或S，条件是当X为O时T为N。还公开了包含式I化合物和药学上可接受的载体的药物组合物。 进一步公开的是治疗哮喘，变态反应和/或炎症的方法，包括向需要这种治疗的哺乳动物分别施用有效量的式I化合物的抗哮喘，抗过敏和/或抗炎， 。

    Breathing exercise device
    7.
    发明授权
    Breathing exercise device 失效
    呼吸运动器材

    公开(公告)号：US4770413A

    公开(公告)日：1988-09-13

    申请号：US42746

    申请日：1987-04-27

    申请人： Michael J. Green

    发明人： Michael J. Green

    IPC分类号： A63B23/18 ,  A63B23/00 ,  A61B5/08

    CPC分类号： A63B23/18 ,  Y10T137/5153

    摘要： A breathing exercise device is formed of a tubular body with a mouthpiece at its proximal end, a resistor sleeve coaxial with the body tube and having a number of resistance openings which align with a body tube opening, and a selective one way flap valve assembly disposed at the distal end of the body tube. The flap valve assembly can be rotated 180 degrees to change the mode of the breathing exercise device from inhalation to exhalation thereapy, or vice versa.

    摘要翻译： 呼吸运动装置由其近端具有口部的管状体形成，与本体管同轴的电阻套筒，并且具有与体管开口对准的多个电阻开口，以及设置有选择性单向瓣阀组件 在体管的远端。 瓣阀组件可旋转180度以将呼吸运动装置的模式从吸入改变为呼气，或反之亦然。

    Transesterification of esters
    9.
    发明授权
    Transesterification of esters 失效
    酯的酯交换反应

    公开(公告)号：US4559180A

    公开(公告)日：1985-12-17

    申请号：US551863

    申请日：1983-11-15

    申请人： Michael J. Green

    发明人： Michael J. Green

    IPC分类号： B01J31/02 ,  C07C68/06 ,  C07C67/02 ,  C07C67/03 ,  C07C68/00

    CPC分类号： C07C68/065 ,  B01J31/0237 ,  B01J31/0247 ,  B01J31/0251 ,  B01J31/0267 ,  B01J2231/40 ,  B01J2231/49

    摘要： A process for the transesterification of a carboxylic or carbonic acid ester comprises reacting the carboxylic or carbonic acid ester under transesterification conditions with an alcohol in the presence, as catalyst, of either (i) a Group V element-containing Lewis base and an epoxide or (ii) a cyclic amidine.The Lewis base can be an organic compound containing trivalent phosphorus or nitrogen and can be an amine, for example an amidine.The process can be operated in the liquid phase at a temperature of from 15.degree. to 150.degree. C., and the catalyst is employed in solution.Preferred catalysts are those where the cyclic amidine forms part of a fused ring system containing six and five membered rings, six and seven membered rings or two six membered rings.

    摘要翻译： 羧酸或碳酸酯的酯交换反应的方法包括在酯交换反应条件下，在（i）含有V族元素的路易斯碱和环氧化物的催化剂存在下，使羧酸或碳酸酯与醇反应，或 （ii）环状脒。 路易斯碱可以是含有三价磷或氮的有机化合物，并且可以是胺，例如脒。 该方法可以在液相中在15至150℃的温度下操作，催化剂用于溶液中。 优选的催化剂是其中环状脒形成包含六元和五元环，六元和七元环或六元环的稠环体系的一部分的催化剂。