Plant Recombinant Human CTLA4IG and a Method for Producing the Same
    1.
    发明申请
    Plant Recombinant Human CTLA4IG and a Method for Producing the Same 审中-公开
    植物重组人CTLA4IG及其生产方法

    公开(公告)号:US20100189717A1

    公开(公告)日:2010-07-29

    申请号:US12668766

    申请日:2008-07-09

    摘要: The present invention provides a recombinant vector pBI-3D-hGalT or pBI-35S-hGalT containing a human β1,4-galactosyltransferase gene; a cell line transformed with a recombinant vector pMYN414 containing a cytotoxic T-lymphocyte anti-gen A-immunoglobulin (CTLA4Ig) fusion protein gene and the recombinant vector pBI-3D-hGalT or pBI-355-hGalT; and a method for producing a plant-derived recombinant human CTLA4Ig (CTLA4Igp) fusion protein with a human glycan structure using the same. The plant cell-derived recombinant human CTLA4Ig fusion protein (CTLA4Igp), which has a human glycan structure and is produced according to the present invention, exhibits an improved in vivo half life as compared to conventional plant-derived proteins, due to the presence of a human-like glycan structure. Consequently, the present invention using the plant expression system enables low-cost mass production of a CTLA4Igp fusion protein having an immunosuppressive activity comparable to that of the CTLA4IgM fusion protein expressed in conventional animal cell expression systems.

    摘要翻译: 本发明提供了含有人和重组1,4-半乳糖基转移酶基因的重组载体pBI-3D-hGalT或pBI-35S-hGalT; 用含有细胞毒性T淋巴细胞抗A型免疫球蛋白(CTLA4Ig)融合蛋白基因和重组载体pBI-3D-hGalT或pBI-355-hGalT的重组载体pMYN414转化的细胞系; 以及使用其使用具有人聚糖结构的植物来源的重组人CTLA4Ig(CTLA4Igp)融合蛋白的方法。 具有人聚糖结构并根据本发明生产的植物细胞衍生的重组人CTLA4Ig融合蛋白(CTLA4Igp)与常规植物衍生的蛋白质相比显示出与常规植物衍生的蛋白质相比改善的体内半衰期, 人类聚糖结构。 因此,使用植物表达系统的本发明能够低成本大规模生产具有与常规动物细胞表达系统中表达的CTLA4IgM融合蛋白相当的免疫抑制活性的CTLA4Igp融合蛋白。

    Liquid crystal display and driving method thereof
    2.
    发明授权
    Liquid crystal display and driving method thereof 有权
    液晶显示及其驱动方法

    公开(公告)号:US08446395B2

    公开(公告)日:2013-05-21

    申请号:US13051406

    申请日:2011-03-18

    IPC分类号: G09G5/00

    摘要: A liquid crystal display device includes a liquid crystal display panel including a plurality of data lines to which a data voltage is supplied, a plurality of gate lines to which a gate pulse is supplied, and a plurality of liquid crystal cells, a data drive circuit to invert a polarity of the data voltage in response to a polarity control signal and to output the data voltage to the data lines in response to a source output enable signal, a gate drive circuit to supply the gate pulse to the gate lines, and a POL/SOE logic circuit to invert the polarity control signal for every frame period except at Nth-multiple frame period (where N is a positive integer), wherein the POL/SOE logic circuit controls the polarity control signal at every Nth-multiple frame period such that the polarity of the data voltage is the same as the previous frame period and controls a pulse width of the source output enable signal at every Nth-multiple frame period to be longer than for the other frame periods.

    摘要翻译: 一种液晶显示装置,包括:液晶显示面板,包括提供数据电压的多条数据线,提供栅极脉冲的多条栅极线,以及多个液晶单元,数据驱动电路 响应于极性控制信号反转数据电压的极性,并且响应于源极输出使能信号而将数据电压输出到数据线,栅极驱动电路将栅极脉冲提供给栅极线,以及 POL / SOE逻辑电路,用于在第N个多个帧周期(其中N为正整数)之外的每个帧周期反转极性控制信号,其中POL / SOE逻辑电路在每N个多个帧周期控制极性控制信号 使得数据电压的极性与前一帧周期相同,并且在每N个多个帧周期控制源输出使能信号的脉冲宽度比其他帧周期长 。

    Poly(arylene ether) copolymer having cation-exchange group, process of manufacturing the same, and use thereof
    3.
    发明授权
    Poly(arylene ether) copolymer having cation-exchange group, process of manufacturing the same, and use thereof 有权
    具有阳离子交换基团的聚(亚芳基醚)共聚物,其制造方法及其用途

    公开(公告)号:US08084568B1

    公开(公告)日:2011-12-27

    申请号:US12960889

    申请日:2010-12-06

    IPC分类号: C08G8/02

    摘要: The present invention relates to a poly(arylene ether) copolymer having an ion exchange group, particularly a positive ion exchange group, a method for manufacturing the same, and use thereof. In the poly(arylene ether) copolymer having the ion exchange group according to the present invention, physical characteristics, ion exchanging ability, metal ion adsorption ability and a processability are excellent, and thus the copolymer can be molded in various shapes and can be extensively applied to various fields such as recovering of organic metal, air purification, catalysts, water treatment, medical fields and separating of proteins.

    摘要翻译: 本发明涉及具有离子交换基团的聚(亚芳基醚)共聚物,特别是正离子交换基团,其制造方法及其用途。 在根据本发明的具有离子交换基团的聚(亚芳基醚)共聚物中,物理特性,离子交换能力,金属离子吸附能力和加工性优异,因此共聚物可以模塑成各种形状并且可广泛地 适用于有机金属回收,空气净化,催化剂,水处理,医疗领域和蛋白质分离等各个领域。

    Field emission lamp
    5.
    发明授权
    Field emission lamp 有权
    场发射灯

    公开(公告)号:US08253317B2

    公开(公告)日:2012-08-28

    申请号:US12842523

    申请日:2010-07-23

    IPC分类号: H01J1/62

    摘要: Provided is a field emission lamp (FEL), which includes a plurality of cathode electrodes formed above a first substrate, an anode electrode formed under a second substrate to face the cathode electrode, a fluorescent layer composed of red, green and blue (RGB) patterns formed alternately on the anode electrode in an oblique direction, and a plurality of emitters formed on the cathode electrodes to correspond to the RGB patterns. According to the present invention, as an FEL having a fast response time is used as a backlight unit, a color breaking phenomenon can be prevented in a color sequential driving method.

    摘要翻译: 本发明提供一种场致发射灯(FEL),其包括形成在第一基板上的多个阴极电极,形成在第二基板下方的与阴极电极对置的阳极电极,由红色,绿色和蓝色(RGB)构成的荧光层, 在阳极电极上交替地沿倾斜方向形成的图案,以及形成在阴极电极上以对应于RGB图案的多个发射体。 根据本发明,由于使用具有快速响应时间的FEL作为背光单元,因此可以防止在彩色顺序驱动方法中发生颜色破坏现象。

    PROBE CARD
    7.
    发明申请
    PROBE CARD 审中-公开
    探针卡

    公开(公告)号:US20120081140A1

    公开(公告)日:2012-04-05

    申请号:US13322416

    申请日:2010-04-22

    IPC分类号: G01R1/067

    摘要: Provided is a probe card which has a space transformer which may be effectively changed to correspond to a change in wafer chip structure and is capable of maximizing acceptable channels of the space transformer. The probe card for testing a semiconductor chip on a wafer includes: a space transformer body in which a plurality of unit probe modules are arranged at intervals; a main circuit board to which an electrical signal is applied from an external test device; a reinforcement plate for supporting the main circuit board such that the unit probe modules become stable against an external effect; a standing conductive medium which is inserted into a penetration portion provided in the space transformer body; a lower surface circuit board in which the standing conductive medium is electrically connected to the unit probe module as a flexible conductive medium and the standing conductive media are mounted; and a mutual connection member for electrically connecting the lower surface circuit board to the main circuit board.

    摘要翻译: 提供了一种具有可以有效地改变以对应于晶片芯片结构的变化并且能够使空间变压器的可接受的通道最大化的空间变压器的探针卡。 用于测试晶片上的半导体芯片的探针卡包括:空间变换器主体,多个单元探针模块间隔排列; 主电路板,从外部测试装置向其施加电信号; 用于支撑主电路板的加强板,使得单元探针模块抵抗外部效应变得稳定; 插入到设置在所述空间变换器主体中的贯通部的立体导电介质; 其中,所述立体导电介质与所述单元探针模块电连接为柔性导电介质并且所述直立导电介质安装在其中; 以及用于将下表面电路板电连接到主电路板的相互连接构件。

    Liquid crystal display and driving method thereof
    8.
    发明申请
    Liquid crystal display and driving method thereof 有权
    液晶显示及其驱动方法

    公开(公告)号:US20080170024A1

    公开(公告)日:2008-07-17

    申请号:US12003585

    申请日:2007-12-28

    IPC分类号: G09G3/36

    摘要: A liquid crystal display device includes a liquid crystal display panel including a plurality of data lines to which a data voltage is supplied, a plurality of gate lines to which a gate pulse is supplied, and a plurality of liquid crystal cells, a data drive circuit to invert a polarity of the data voltage in response to a polarity control signal and to output the data voltage to the data lines in response to a source output enable signal, a gate drive circuit to supply the gate pulse to the gate lines, and a POL/SOE logic circuit to invert the polarity control signal for every frame period except at Nth-multiple frame period (where N is a positive integer), wherein the POL/SOE logic circuit controls the polarity control signal at every Nth-multiple frame period such that the polarity of the data voltage is the same as the previous frame period and controls a pulse width of the source output enable signal at every Nth-multiple frame period to be longer than for the other frame periods.

    摘要翻译: 一种液晶显示装置,包括:液晶显示面板,包括提供数据电压的多条数据线,提供栅极脉冲的多条栅极线,以及多个液晶单元,数据驱动电路 响应于极性控制信号反转数据电压的极性,并且响应于源极输出使能信号而将数据电压输出到数据线,栅极驱动电路将栅极脉冲提供给栅极线,以及 POL / SOE逻辑电路,用于在第N个多个帧周期(其中N为正整数)之外的每个帧周期反转极性控制信号,其中POL / SOE逻辑电路在每N个多个帧周期控制极性控制信号 使得数据电压的极性与前一帧周期相同,并且在每N个多个帧周期控制源输出使能信号的脉冲宽度比其他帧周期长 。

    Micro cantilever style contact pin structure for wafer probing
    9.
    发明授权
    Micro cantilever style contact pin structure for wafer probing 失效
    微悬臂式接触针结构用于晶圆探测

    公开(公告)号:US06414501B2

    公开(公告)日:2002-07-02

    申请号:US09965607

    申请日:2001-09-27

    IPC分类号: G01R3102

    摘要: The present invention is to provide a micro cantilever-type probe disposed on a probe card, having such appropriate elasticity and mechanical strength that the probe would recover its unforced shape after deformation during an inspection and maintain its original shape even after three hundred thousand uses. The present invention provides a probe card which has an electrically insulated substrate fixed on a circuit board; a plurality of elastic probes with a sharpened end fixed on the insulated substrate; and wiring formed on the probe, the insulated substrate and the circuit board. The inventive probe is manufactured by patterning a substrate using photolithography and etching a portion except a pattern-defined portion. The probe is coated by metal layer(s).

    摘要翻译: 本发明提供一种设置在探针卡上的微型悬臂式探头,其具有适当的弹性和机械强度,使得探针在检查过程中变形后能够恢复其非强制形状,并且即使在三十万次使用后也保持其原始形状。 本发明提供了一种探针卡,其具有固定在电路板上的电绝缘基板; 多个具有固定在所述绝缘基板上的尖端的弹性探针; 以及形成在探针,绝缘基板和电路板上的布线。 本发明的探针通过使用光刻图案化衬底并蚀刻除了图案限定部分之外的部分来制造。 探针被金属层涂覆。

    Current detecting circuit using pulse transformer
    10.
    发明授权
    Current detecting circuit using pulse transformer 失效
    电流检测电路采用脉冲变压器

    公开(公告)号:US5235224A

    公开(公告)日:1993-08-10

    申请号:US780777

    申请日:1991-10-23

    CPC分类号: G01R15/18 H03K17/16 H03K17/61

    摘要: A detecting circuit is provided with at least one transformer, in which a first transformer is connected at its primary winding to an input power source and has two windings at its output portion to control the operation of two transistors respectively mounted in two switching portions in turn, the detecting resistor is coupled to the first transformer to detect a changing amount of current applied to a load, and a second transformer is provided with two input windings having a tap connected to the resistor and two output windings facing to the input windings, thereby outputting the signals isolated from the ground.

    摘要翻译: 检测电路设置有至少一个变压器,其中第一变压器在其初级绕组处连接到输入电源,并且在其输出部分具有两个绕组,以依次控制分别安装在两个开关部分中的两个晶体管的操作 检测电阻器耦合到第一变压器以检测施加到负载的电流的变化量,并且第二变压器设置有具有连接到电阻器的抽头和面向输入绕组的两个输出绕组的两个输入绕组,由此 输出从地面隔离的信号。