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36 条记录 (耗时 0.026 秒)

    Hermetically sealed microchip reservoir devices
    1.
    发明申请
    Hermetically sealed microchip reservoir devices 有权
    密封微芯片油藏装置

    公开(公告)号：US20050077584A1

    公开(公告)日：2005-04-14

    申请号：US11005391

    申请日：2004-12-06

    申请人： Scott Uhland ,  Benjamin Polito ,  Stephen Herman ,  John Santini ,  John Maloney

    发明人： Scott Uhland ,  Benjamin Polito ,  Stephen Herman ,  John Santini ,  John Maloney

    IPC分类号： B81C3/00 ,  A61K9/00 ,  A61K9/22 ,  B23K1/06 ,  B23K26/00 ,  B81B1/00 ,  H01L27/14

    CPC分类号： A61K9/0097

    摘要： Devices are provided for the controlled exposure or release of contents stored in hermetically sealed reservoirs. The devices comprise a primary substrate having a front side and a back side, and including one or more hermetic sealing materials; a plurality of reservoirs in the primary substrate positioned between the front side and the back side; reservoir contents, which comprise chemical molecules (such as drugs) or a secondary device (such as a glucose sensor), located inside the reservoirs; a hermetic sealing substrate having a surface composed of one or more hermetic sealing materials; and a hermetic seal formed between and joining the primary substrate and the hermetic sealing substrate, wherein the hermetic seal independently seals the reservoirs.

    摘要翻译： 提供了用于控制曝光或释放存储在密封储存器中的内容物的装置。 这些装置包括具有前侧和后侧的主基板，并且包括一个或多个密封材料; 位于前侧和后侧之间的主要基底中的多个储存器; 包括化学分子（如药物）或位于储存器内部的次级装置（如葡萄糖传感器）的储存器内容物; 具有由一种或多种密封材料构成的表面的气密密封基材; 以及形成在主基板和气密密封基板之间并与其接合的气密密封件，其中气密密封独立地密封储存器。

    Medical device for sensing glucose
    5.
    发明申请
    Medical device for sensing glucose 有权
    用于感测葡萄糖的医疗设备

    公开(公告)号：US20050096587A1

    公开(公告)日：2005-05-05

    申请号：US10980551

    申请日：2004-11-03

    申请人： John Santini ,  Stephen Herman

    发明人： John Santini ,  Stephen Herman

    IPC分类号： A61B5/00 ,  A61M31/00 ,  A61N1/00

    CPC分类号： A61B5/14865 ,  A61B5/0031 ,  A61B5/1486 ,  A61B5/4839 ,  B33Y80/00

    摘要： Medical devices, utilizing multiple reservoirs to protect and selectively expose sensors or other reservoir contents, are provided having (i) a reservoir contents destruction mechanism to interrupt the release or exposure of reservoir contents, for example, to deactivate an unneeded sensor and prevent it from negatively impacting other sensors, (ii) a protective covering material layer over the sensor underneath the reservoir cap, which protects the sensor membrane and sensor during reservoir cap disintegration and then is removed, (iii) a device design for containing sensors in shallow, wide reservoir structures to enhance sensor exposure by minimizing molecular diffusion distances, (iv) an implantable sensor unit and a separate drug delivery unit, or (v) combinations thereof.

    摘要翻译： 提供了利用多个储存器来保护和选择性地暴露传感器或其他贮存器内容物的医疗装置，其具有（i）用于中断储存器内容物的释放或暴露的储存器内容物破坏机制，例如，去激活不需要的传感器并防止 负面影响其他传感器，（ii）储存器盖下方的传感器上方的保护性覆盖材料层，其在储存器盖分解期间保护传感器膜和传感器然后被去除，（iii）用于在浅的，宽的 储存器结构，以通过最小化分子扩散距离来增强传感器暴露，（iv）植入式传感器单元和单独的药物递送单元，或（v）其组合。

    Device for controlled reservoir opening with reinforced reservoir caps
    7.
    发明申请
    Device for controlled reservoir opening with reinforced reservoir caps 审中-公开
    受控储层开启装置，加强储层盖

    公开(公告)号：US20050143715A1

    公开(公告)日：2005-06-30

    申请号：US10937616

    申请日：2004-09-09

    申请人： Michael Cima ,  John Santini ,  Stephen Herman

    发明人： Michael Cima ,  John Santini ,  Stephen Herman

    IPC分类号： A61K9/00 ,  A61K9/22 ,  A61M31/00

    CPC分类号： A61K9/0097 ,  A61K9/0009 ,  Y10T137/8242

    摘要： Device are provided for the controlled release or exposure of molecules or secondary devices comprising a substrate; a plurality of reservoirs located in the substrate; reservoir contents comprising molecules, a secondary device, or both, isolated inside the reservoirs; reservoir caps positioned on the reservoirs over the reservoir contents, wherein the reservoir caps (which can comprise a metal film) are mechanically reinforced with a second material deposited and patterned on the surface of the metal film inside the reservoir or on the surface of the metal film outside the reservoir or on both of said surfaces; and control circuitry and a power source for disintegrating the reservoir caps to initiate exposure or release of the reservoir contents in selected reservoirs.

    摘要翻译： 提供了用于受控释放或暴露包括基底的分子或二次装置的装置; 位于所述基板中的多个储存器; 储存器内容物包含分离在储存器内部的分子，次要装置或二者; 储存器盖位于储存器上方的储存器内容物上，其中储存器盖（其可以包括金属膜）用沉积和图案化的第二材料机械地增强，该金属膜在储存器内部或金属表面上的金属膜的表面上 在所述储存器外部或所述两个所述表面上的膜; 以及控制电路和用于分解储存器盖的电源，以开始在所选择的储存器中储存器内容物的曝光或释放。

    LED/phosphor-LED hybrid lighting systems
    8.
    发明授权
    LED/phosphor-LED hybrid lighting systems 有权
    LED /荧光粉 - LED混合照明系统

    公开(公告)号：US06692136B2

    公开(公告)日：2004-02-17

    申请号：US10302315

    申请日：2002-11-22

    申请人： Thomas M. Marshall ,  Michael D. Pashley ,  Stephen Herman

    发明人： Thomas M. Marshall ,  Michael D. Pashley ,  Stephen Herman

    IPC分类号： F21V900

    CPC分类号： H01L25/0753 ,  H01L33/50 ,  H01L33/504 ,  H01L2924/0002 ,  Y10S362/80 ,  H01L2924/00

    摘要： A hybrid lighting system for producing white light including at least one light emitting diode and phosphor-light emitting diode. The hybrid lighting system exhibits improved performance over conventional LED lighting systems that use LEDs or phosphor-LEDs to produce white light. In particular, the hybrid system of the invention permits different lighting system performance parameters to be addressed and optimized as deemed important, by varying the color and number of the LEDs and/or the phosphor of the phosphor LED.

    摘要翻译： 一种用于产生包括至少一个发光二极管和荧光发光二极管的白光的混合照明系统。 与使用LED或荧光体LED产生白光的传统LED照明系统相比，混合照明系统具有改进的性能。 特别地，通过改变荧光体LED的LED和/或荧光体的颜色和数量，本发明的混合系统允许不同的照明系统性能参数被解决和优化为重要的。