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    Process for manufacturing an analysis module with accessible electrically conductive contact pads for a microfluidic analytical system
    3.
    发明申请
    Process for manufacturing an analysis module with accessible electrically conductive contact pads for a microfluidic analytical system 审中-公开
    用于制造具有用于微流体分析系统的可触及导电接触垫的分析模块的方法

    公开(公告)号：US20060065361A1

    公开(公告)日：2006-03-30

    申请号：US10957440

    申请日：2004-09-30

    申请人： Matthias Stiene ,  Tanja Richter ,  James Rodgers ,  Margaret MacLennan ,  James Moffat ,  Alan McNeilage

    发明人： Matthias Stiene ,  Tanja Richter ,  James Rodgers ,  Margaret MacLennan ,  James Moffat ,  Alan McNeilage

    IPC分类号： B32B37/00

    CPC分类号： B01L3/502715 ,  B01L3/502707 ,  B01L2200/12 ,  B01L2300/0645 ,  B01L2300/0887 ,  G01N33/48785 ,  H05K1/0272 ,  H05K1/117 ,  H05K3/20

    摘要： A method for manufacturing an analysis module with accessible electrically conductive contact pads includes forming an insulating substrate with an upper surface, a microchannel(s) within the upper surface, and electrically conductive contact pad(s) disposed on the upper surface. The method also includes producing a laminate layer with a bottom surface, electrode(s) on the laminate layer bottom surface, and electrically conductive trace(s) on the laminate layer bottom surface. The method further includes adhering the laminate layer to the insulating substrate such that a portion of the bottom surface of the laminate layer is adhered to a portion of the upper surface of the insulating substrate, each electrode is exposed to at least one microchannel; and each electrically conductive trace is electrically contacted to at least one electrically conductive contact pad. Furthermore, the adhering is such that at least one surface of the electrically conductive contact pad remains exposed and accessible for electrical connection.

    摘要翻译： 用于制造具有可触及的导电接触焊盘的分析模块的方法包括：形成具有上表面的绝缘衬底，上表面内的微通道和设置在上表面上的导电接触焊盘。 该方法还包括制备具有底表面的层压层，层压层底表面上的电极以及层压层底表面上的导电迹线。 该方法还包括将层压层粘合到绝缘基板上，使得层压层的底表面的一部分粘附到绝缘基板的上表面的一部分，每个电极暴露于至少一个微通道; 并且每个导电迹线与至少一个导电接触焊盘电接触。 此外，粘合使得导电接触焊盘的至少一个表面保持暴露并且可访问用于电连接。

    Microfluidic analytical system with accessible electrically conductive contact pads
    4.
    发明申请
    Microfluidic analytical system with accessible electrically conductive contact pads 审中-公开
    具有可触及导电接触垫的微流体分析系统

    公开(公告)号：US20060065532A1

    公开(公告)日：2006-03-30

    申请号：US10957505

    申请日：2004-09-30

    申请人： Matthias Stiene ,  Tanja Richter ,  James Rodgers ,  Margaret MacLennan ,  James Moffat ,  Alan McNeilage

    发明人： Matthias Stiene ,  Tanja Richter ,  James Rodgers ,  Margaret MacLennan ,  James Moffat ,  Alan McNeilage

    IPC分类号： B01L3/00 ,  G01N27/447

    CPC分类号： B01L3/502707 ,  B01L3/502715 ,  B01L2200/0689 ,  B01L2300/0645 ,  B01L2300/0825 ,  B01L2300/0887 ,  G01N33/48792

    摘要： A microfluidic analytical system for monitoring an analyte (such as glucose) in a fluid sample (e.g., blood or ISF) includes an analysis module and an electrical device (for example, a meter or power supply). The analysis module includes an insulating substrate and a microchannel(s) within the insulating substrate's upper surface. The analysis module also includes a conductive contact pad(s) disposed on the upper surface of the insulating substrate and an electrode(s), with the electrode(s) being disposed over the microchannel. In addition, the analysis module includes an electrically conductive trace(s) that electrically connects the electrode to at least one electrically conductive contact pad. The analysis module also has a laminate layer disposed over the electrode, the electrically conductive trace, the microchannel and a portion of the upper surface of the insulating substrate. The electrically conductive contact pad of the analysis module has an accessible exposed surface for electrical connection to the electrical device.

    摘要翻译： 用于监测流体样品（例如血液或ISF）中的分析物（例如葡萄糖）的微流体分析系统包括分析模块和电气装置（例如，仪表或电源）。 分析模块包括绝缘基板和绝缘基板的上表面内的微通道。 分析模块还包括设置在绝缘基板的上表面上的导电接触焊盘和电极，其中电极设置在微通道上。 另外，分析模块包括将电极电连接到至少一个导电接触焊盘的导电迹线。 分析模块还具有设置在电极，导电迹线，微通道和绝缘基板的上表面的一部分上的层压层。 分析模块的导电接触焊盘具有可触及的暴露表面，用于电连接到电气设备。

    Method for manufacturing an enzymatic electrochemical-based sensor
    7.
    发明申请
    Method for manufacturing an enzymatic electrochemical-based sensor 审中-公开
    酶电化学传感器的制造方法

    公开(公告)号：US20060226007A1

    公开(公告)日：2006-10-12

    申请号：US11118894

    申请日：2005-04-28

    申请人： James Rodgers ,  Zuifang Liu ,  Alan McNeilage ,  Margaret MacLennan ,  James Moffat ,  Geoffrey Lillie ,  Michael MacDonald

    发明人： James Rodgers ,  Zuifang Liu ,  Alan McNeilage ,  Margaret MacLennan ,  James Moffat ,  Geoffrey Lillie ,  Michael MacDonald

    IPC分类号： C12Q1/00

    CPC分类号： C12Q1/004

    摘要： A method for manufacturing a portion of an enzymatic electrochemical-based sensor includes applying a water-miscible conductive ink to a substrate of an enzymatic electrochemical-based sensor. The water-miscible conductive ink includes a conductive material, an enzyme, a mediator, and a binding agent (that becomes operatively water-insoluble upon drying) formulated as a water-miscible aqueous-based dispersion. The method further includes the drying the water-miscible conductive ink to form a conductive layer on the substrate that includes an operatively water-insoluble binding agent.

    摘要翻译： 用于制造酶电化学传感器的一部分的方法包括将水混溶性导电油墨施加到酶电化学传感器的基底上。 水混溶性导电油墨包括配制为水混溶性水基分散体的导电材料，酶，介质和粘合剂（其在干燥时变得可操作地不溶于水）。 该方法还包括干燥水混溶性导电油墨以在基材上形成包含可操作的水不溶性粘合剂的导电层。

    Fusible conductive ink for use in manufacturing microfluidic analytical systems
    8.
    发明申请
    Fusible conductive ink for use in manufacturing microfluidic analytical systems 有权
    用于制造微流体分析系统的可熔导电油墨

    公开(公告)号：US20060074143A1

    公开(公告)日：2006-04-06

    申请号：US10957470

    申请日：2004-09-30

    申请人： James Rodgers ,  Margaret McClennan ,  James Moffat ,  Alan McNeilage

    发明人： James Rodgers ,  Margaret McClennan ,  James Moffat ,  Alan McNeilage

    IPC分类号： C03C17/00 ,  C09D11/00

    CPC分类号： C09D11/102

    摘要： A fusible conductive ink for use in manufacturing microfluidic analytical systems includes micronised powder containing platinum and carbon, poly(bisphenol A-co-epichlorohydrin)-glycidyl end capped polymer, and a solvent. In addition, the ratio of micronised powder to poly(bisphenol A-co-epichlorohydrin)-glycidyl end capped polymer is in the range of 3:1 to 1:3. The fusible conductive inks can be employed in the manufacturing of microfluidic systems to form electrodes, electrically conductive traces and/or electrically conductive contact pads.

    摘要翻译： 用于制造微流体分析系统的可熔性导电油墨包括含有铂和碳的微粉化粉末，聚（双酚A共 - 表氯醇） - 缩水甘油基封端的聚合物和溶剂。 此外，微粉化粉末与聚（双酚A-共 - 表氯醇） - 缩水甘油基封端聚合物的比例在3:1至1:3的范围内。 可熔融导电油墨可用于制造微流体系统以形成电极，导电迹线和/或导电接触焊盘。

    Fusible conductive ink for use in manufacturing microfluidic analytical systems
    9.
    发明授权
    Fusible conductive ink for use in manufacturing microfluidic analytical systems 有权
    用于制造微流体分析系统的可熔导电油墨

    公开(公告)号：US07402616B2

    公开(公告)日：2008-07-22

    申请号：US10957470

    申请日：2004-09-30

    申请人： James Iain Rodgers ,  Margaret Maclennan ,  James Moffat ,  Alan McNeilage

    发明人： James Iain Rodgers ,  Margaret Maclennan ,  James Moffat ,  Alan McNeilage

    IPC分类号： C09D11/00 ,  C09D11/10

    CPC分类号： C09D11/102

    摘要： A fusible conductive ink for use in manufacturing microfluidic analytical systems includes micronised powder containing platinum and carbon, poly(bisphenol A-co-epichlorohydrin)-glycidyl end capped polymer, and a solvent. In addition, the ratio of micronised powder to poly(bisphenol A-co-epichlorohydrin)-glycidyl end capped polymer is in the range of 3:1 to 1:3. The fusible conductive inks can be employed in the manufacturing of microfluidic systems to form electrodes, electrically conductive traces and/or electrically conductive contact pads.

    摘要翻译： 用于制造微流体分析系统的可熔性导电油墨包括含有铂和碳的微粉化粉末，聚（双酚A共 - 表氯醇） - 缩水甘油基封端的聚合物和溶剂。 此外，微粉化粉末与聚（双酚A-共 - 表氯醇） - 缩水甘油基封端聚合物的比例在3:1至1:3的范围内。 可熔融导电油墨可用于制造微流体系统以形成电极，导电迹线和/或导电接触焊盘。