摘要:
Novel inhibitors of dipeptidyl peptidase IV (DPP IV), pharmaceutical compositions comprising therapeutically effective amounts of novel inhibitors of DPP IV, and novel methods of treating medical conditions are provided. The novel inhibitors of DPP IV described herein are useful in the treatment of neurological disorders, diabetes, inflammatory disorders such as arthritis, obesity, osteoporosis, and of such other enumerated conditions as can be treated with inhibitors of DPP IV.
摘要:
Symmetrically disubstituted aromatic compounds and pharmaceutical compositions containing such compounds that inhibit and/or modulate the activity of poly(ADP-ribose) glycohydrolase, also known as PARG, are described. The invention is also directed to the therapeutic or prophylactic use of such compounds and compositions, and to methods of treating diseases and disorders described herein, by administering effective amounts of such compounds.
摘要:
The present invention relate to phosphinic alkanoic acid derivatives that inhibit N-Acetylated .alpha.-Linked Acidic Dipeptidase (NAALADase) enzyme activity, pharmaceutical compositions comprising the same, and methods of using the same to inhibit NAALADase activity and to treat glutamate abnormalities and prostate diseases.
摘要:
The disclosure relates to methods for preparing urushiol from plants including, for example, poison ivy or poison oak. The methods include extraction of plant material using a primary organic solvent more polar than ethanol, followed by a solvent extraction using substantially immiscible solvents having substantially different polarities, such as hexane and acetonitrile. The method can include further purification, such as by fractionation of solvent-extracted materials using a thiazole-derivatized silica gel chromatography medium. The extracts thus generated can exhibit greater purity, higher concentration, and greater stability than extracts made using previously-known methods. The extracts can be particularly suitable for use in immunotherapeutic methods, such as desensitizing individuals who normally develop allergic contact dermatitis attributable to poison ivy or poison oak.
摘要:
Disclosed is an icon generation method, comprising: adjusting an original icon to a preset size for a certain resolution environment; determining statistics for the color values of all pixels of the original icon and calculating a dominant hue of the original icon; generating a background color based on a hue angle of the dominant hue and preset values of color saturation and brightness; applying the background color to a preset color gradient template to generate an icon background; cutting the adjusted icon by using a preset icon edge cutting template; and combining the icon background, the cut icon, and a preset icon foreground template to generate a final icon. Through the disclosed solution, new icons complying with a unified system style can be generated, and content consistency of the new icons can be best ensured.
摘要:
Provided is a cleaning process of producing lactic acid. Firstly saccharification liquid is prepared through saccharated materials, then fermented with nutritive materials and lactic acid bacteria, and liquid alkali is used to adjust the pH. The fermentation broth is filtrated with porous membrane, and the lactic acid bacteria in the interception liquid are then reintroduced into the porous membrane for recycling. The permeate from porous membrane is subjected to nanofiltration to be decoloured and purified. The concentrated solution from nanofiltration and the cleaning liquid from fermentation tank and its affiliated equipment are filtrated and sterilized by using ceramic membrane, and then are reintroduced into the fermentation unit for recycling. The permeate from nanofiltration is then subjected to bipolar electrodialysis system to prepare lactic acid, and the liquid alkali produced at the same time is reintroduced into the fermentation tank for recycling. The lactic acid is finally concentrated by using vacuum distillation. The process recycles the bacteria in the liquid alkali and matured fermentation broth, and is characterized by low material consumption and emission, low pollution, reduced cost and cleanness and environmentally protection of the whole production process.
摘要:
Disclosed is an icon generation method, comprising: adjusting an original icon to a preset size for a certain resolution environment; determining statistics for the color values of all pixels of the original icon and calculating a dominant hue of the original icon; generating a background color based on a hue angle of the dominant hue and preset values of color saturation and brightness; applying the background color to a preset color gradient template to generate an icon background; cutting the adjusted icon by using a preset icon edge cutting template; and combining the icon background, the cut icon, and a preset icon foreground template to generate a final icon. Through the disclosed solution, new icons complying with a unified system style can be generated, and content consistency of the new icons can be best ensured.
摘要:
The invention comprises novel inhibitors of dipeptidyl peptidase IV (DPP-IV) with beta blocker activity, pharmaceutical compositions comprising therapeutically effective amounts of novel inhibitors of DPP-IV, and novel methods of treating medical conditions are provided. The novel inhibitors of DPP-IV described herein are useful in the treatment of neurological disorders, diabetes, inflammatory disorders such as arthritis, obesity, osteoporosis, hypertension, and glaucoma of such other enumerated conditions as can be treated with inhibitors of DPP-IV and beta blockers.
摘要:
The invention comprises novel inhibitors of dipeptidyl peptidase IV (DPP-IV) with beta blocker activity, pharmaceutical compositions comprising therapeutically effective amounts of novel inhibitors of DPP-IV, and novel methods of treating medical conditions are provided. The novel inhibitors of DPP-IV described herein are useful in the treatment of neurological disorders, diabetes, inflammatory disorders such as arthritis, obesity, osteoporosis, hypertension, and glaucoma of such other enumerated conditions as can be treated with inhibitors of DPP-IV and beta blockers.
摘要:
The present disclosure is drawn to a method for unlocking a mobile device. The method comprises the steps of adopting a configuration file to define an operational input for unlocking the mobile device, adopting the configuration file to define at least one animation and/or effect, adopting the configuration file to establish a relationship between the operational input and the at least one animation and/or effect, and triggering the animation and/or effect when unlocking the mobile device. The technical scheme of the present disclosure combines the operational input for unlocking the mobile device with the animation and/or effect, helping to improve the user experience of unlocking a mobile device.