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    Device, system and method of detecting targets in a fluid sample
    1.
    发明申请
    Device, system and method of detecting targets in a fluid sample 审中-公开
    检测流体样本中目标物的装置，系统和方法

    公开(公告)号：US20050063869A1

    公开(公告)日：2005-03-24

    申请号：US10670912

    申请日：2003-09-24

    申请人： Stephane Follonier ,  Pierre Indermuhle

    发明人： Stephane Follonier ,  Pierre Indermuhle

    IPC分类号： G01N21/03 ,  G01N21/05 ,  G01N21/00

    CPC分类号： G01N33/54373 ,  G01N21/0303 ,  G01N21/05 ,  G01N2021/0346

    摘要： The present invention provides a biochemical detection system that comprises an exchangeable cartridge unit with light guiding tubes pre-coated with capture agent(s) and an optical detection unit. Upon flowing the liquid or gaseous sample containing the target(s) through the tube, the target(s) bind(s) to the capture agent(s) and is (are) detected by the amount of light or the variation of its properties while guided through the tubes. The optical detection unit is comprised of a light emitting element(s), a light connecting element(s) and a light detecting element(s) that delivers the amount of target(s) in the sample under investigation.

    摘要翻译： 本发明提供了一种生物化学检测系统，其包括具有预先涂覆有捕获剂的光导管和光学检测单元的可更换筒单元。 当使含有目标物的液体或气体样品通过管流动时，目标物与捕获剂结合并且通过光量或其性质的变化来检测 同时引导穿过管。 光学检测单元由发光元件，光连接元件和光检测元件组成，其传送被调查样品中的目标物的量。

    Device, system and method of detecting targets in a fluid sample
    2.
    发明申请
    Device, system and method of detecting targets in a fluid sample 审中-公开
    检测流体样本中目标物的装置，系统和方法

    公开(公告)号：US20070141722A1

    公开(公告)日：2007-06-21

    申请号：US10572931

    申请日：2004-09-22

    申请人： Stephane Follonier ,  Pierre Indermuhle

    发明人： Stephane Follonier ,  Pierre Indermuhle

    IPC分类号： G01N33/543

    CPC分类号： G01N33/54373 ,  G01N21/0303 ,  G01N21/05 ,  G01N2021/0346

    摘要： The present invention provides a biochemical detection system that comprises an exchangeable cartridge unit with light guiding tubes pre-coated with capture agent(s) and an optical detection unit Upon flowing the liquid or gaseous sample containing the target(s) through the cartridge until the target(s) bind(s) to the capture agent(s) and is (are) detected by the amount of light or the variation of its properties while guided through the tubes. The optical detection unit is comprised of a light emitting element(s), a light connecting element(s) and a light detecting element(s) that delivers the amount of target(s) in the sample under investigation.

    摘要翻译： 本发明提供了一种生物化学检测系统，其包括具有预先涂覆有捕获剂的光导管的可更换筒单元和光学检测单元。使含有目标物的液体或气体样品通过筒直到 目标（一个或多个）与捕获剂结合，并且在被引导通过管时被光量或其性质的变化所检测。 光学检测单元由发光元件，光连接元件和光检测元件组成，其传送被调查样品中的目标物的量。

    PIPETTE TIP, PIPETTE SYSTEM AND METHOD FOR PERFORMING ANALYSIS WITH THE PIPETTE TIP AND SYSTEM
    3.
    发明申请
    PIPETTE TIP, PIPETTE SYSTEM AND METHOD FOR PERFORMING ANALYSIS WITH THE PIPETTE TIP AND SYSTEM 有权
    PIPETTE提示，PIPETTE系统和使用管道提示和系统进行分析的方法

    公开(公告)号：US20130171673A1

    公开(公告)日：2013-07-04

    申请号：US13807744

    申请日：2011-06-30

    申请人： Stéphane Follonier ,  Linsey Fan ,  Pierre Indermuhle

    发明人： Stéphane Follonier ,  Linsey Fan ,  Pierre Indermuhle

    IPC分类号： G01N33/53 ,  G01N33/543 ,  B01L3/02

    CPC分类号： G01N33/5302 ,  B01L3/021 ,  B01L3/0275 ,  B01L2300/0636 ,  B01L2300/0654 ,  G01N33/54306

    摘要： The present invention relates to a pipette tip (100, 200, 201, 300) comprising a tip body (110) having an inner surface and an outer surface (112). The inner surface (111) defines an inner cavity (120, 320), which has an upper end and a lower end. The upper end has an upper opening (131); and the lower end has a lower opening (141). At least a part of the inner surface (111) is provided with capturing agents (151) of at least one type forming at least one capturing-agent region (150) on the at least one inner surface. The at least one capturing agent region (150) is capable of selectively binding target substances (152) of at least one type comprised in a sample to form at least agent-target conjugates (155), the arrangement of which define at least one agent-target region (156).

    摘要翻译： 本发明涉及一种具有内表面和外表面（112）的末端体（110）的移液管吸头（100,200,301,300）。 内表面（111）限定具有上端和下端的内腔（120,320）。 上端具有上开口（131）; 并且下端具有下开口（141）。 内表面（111）的至少一部分设置有在至少一个内表面上形成至少一个捕获剂区域（150）的至少一种类型的捕获剂（151）。 所述至少一个捕获剂区域（150）能够选择性地结合样品中包含的至少一种类型的目标物质（152）以形成至少一种试剂 - 目标共轭物（155），其排列限定了至少一种试剂 - 目标区域（156）。

    Pipette tip, pipette system and method for performing analysis with the pipette tip and system
    6.
    发明授权
    Pipette tip, pipette system and method for performing analysis with the pipette tip and system 有权
    移液器吸头，移液管系统和使用移液器吸头和系统进行分析的方法

    公开(公告)号：US08940523B2

    公开(公告)日：2015-01-27

    申请号：US13807744

    申请日：2011-06-30

    申请人： Stéphane Follonier ,  Linsey Fan ,  Pierre Indermuhle

    发明人： Stéphane Follonier ,  Linsey Fan ,  Pierre Indermuhle

    IPC分类号： C12M1/34 ,  G01N33/53 ,  B01L3/02 ,  G01N33/543

    CPC分类号： G01N33/5302 ,  B01L3/021 ,  B01L3/0275 ,  B01L2300/0636 ,  B01L2300/0654 ,  G01N33/54306

    摘要： The present invention relates to a pipette tip (100, 200, 201, 300) comprising a tip body (110) having an inner surface and an outer surface (112). The inner surface (111) defines an inner cavity (120, 320), which has an upper end and a lower end. The upper end has an upper opening (131); and the lower end has a lower opening (141). At least a part of the inner surface (111) is provided with capturing agents (151) of at least one type forming at least one capturing-agent region (150) on the at least one inner surface. The at least one capturing agent region (150) is capable of selectively binding target substances (152) of at least one type comprised in a sample to form at least agent-target conjugates (155), the arrangement of which define at least one agent-target region (156).

    摘要翻译： 本发明涉及一种具有内表面和外表面（112）的末端体（110）的移液管吸头（100,200,301,300）。 内表面（111）限定具有上端和下端的内腔（120,320）。 上端具有上开口（131）; 并且下端具有下开口（141）。 内表面（111）的至少一部分设置有在至少一个内表面上形成至少一个捕获剂区域（150）的至少一种类型的捕获剂（151）。 所述至少一个捕获剂区域（150）能够选择性地结合样品中包含的至少一种类型的目标物质（152）以形成至少试剂 - 目标共轭物（155），其排列限定了至少一种试剂 - 目标区域（156）。

    STACKABLE MICRO-FLUIDIC CELLS
    10.
    发明申请
    STACKABLE MICRO-FLUIDIC CELLS 审中-公开
    可堆叠的微流体细胞

    公开(公告)号：US20140170737A1

    公开(公告)日：2014-06-19

    申请号：US14187231

    申请日：2014-02-22

    申请人： Pierre Indermuhle ,  Alexander Stuck ,  Alicia Hegglin

    发明人： Pierre Indermuhle ,  Alexander Stuck ,  Alicia Hegglin

    IPC分类号： G01N33/53

    CPC分类号： G01N33/5304 ,  B01L3/5025 ,  B01L3/502715 ,  B01L3/50857 ,  B01L2200/027 ,  B01L2200/028 ,  B01L2200/0642 ,  B01L2200/16 ,  B01L2300/0829 ,  B01L2300/0864 ,  B01L2300/0874 ,  B01L2400/0406 ,  B01L2400/0688

    摘要： An assay assembly that includes an assay bar having a plurality flow cells is disclosed. Each of the flow cells includes an inlet, an outlet, and an inside surface defining an inner volume. The outlet includes a valve that is configured to retain liquid within the inner volume of the flow cell. Each assay bar is configured to be reversibly stacked upon another assay bar, such that the flow cells of the stacked assay bars are in fluid communication with each other. This way, the outlet of a first flow cell of a first assay bar is in fluid communication with the inlet of a second flow cell of a second assay bar. The assay assembly may include a multitude of assay bars to form a composite assay assembly, with the flow cells of the stacked assay bars being in fluid communication with each other.

    摘要翻译： 公开了一种包含具有多个流动池的分析条的测定组件。 每个流动池包括入口，出口和限定内部容积的内表面。 出口包括被配置成将液体保持在流动池的内部容积内的阀。 每个测定条被配置为可逆地堆叠在另一个测定条上，使得堆叠的测定条的流动池彼此流体连通。 这样，第一测定条的第一流动池的出口与第二测定条的第二流动池的入口流体连通。 测定组件可以包括多个测定条以形成复合测定组件，其中堆叠的测定条的流动池彼此流体连通。