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    METHOD AND APPARATUS FOR CONCENTRATING AND AMPLIFYING NUCLEIC ACID IN SINGLE MICRO CHAMBER
    3.
    发明申请
    METHOD AND APPARATUS FOR CONCENTRATING AND AMPLIFYING NUCLEIC ACID IN SINGLE MICRO CHAMBER 有权
    在单个微室中浓缩和放大核酸的方法和装置

    公开(公告)号：US20070269819A1

    公开(公告)日：2007-11-22

    申请号：US11620961

    申请日：2007-01-08

    申请人： Young-rok KIM ,  Jun-hong MIN ,  In-ho LEE ,  Young-sun LEE ,  Chang-eun YOO ,  Ki-woong HAN

    发明人： Young-rok KIM ,  Jun-hong MIN ,  In-ho LEE ,  Young-sun LEE ,  Chang-eun YOO ,  Ki-woong HAN

    IPC分类号： C12Q1/68 ,  C12M3/00

    CPC分类号： C12Q1/6806 ,  B01L3/5027 ,  B01L3/5088 ,  C12Q1/686 ,  C12Q2565/629 ,  C12Q2537/149 ,  C12Q2527/125

    摘要： A method of sequentially performing concentration and amplification of nucleic acid in a single micro chamber includes: introducing a nucleic acid-containing sample and a solution including a kosmotropic salt to a micro chamber having a hydrophilic interior surface to concentrate the nucleic acid by binding the nucleic acid on the interior surface of the micro chamber; and performing a polymerase chain reaction (PCR) by adding a PCR mixture to the chamber. Since the nucleic acid is reversibly bound to the interior surface of the micro chamber, PCR yield is higher compared with a surface of aluminum oxide in which irreversible binding occurs. In addition, all processes are sequentially performed in a single micro chamber so that the number of samples, consumables, time, and labor for treatment and analysis can be reduced, detection sensitivity can be improved, and risk of sample cross contamination significantly reduced without sample loss by eliminating transporting of the sample. A complete automated system for concentration and amplification of nucleic acid is thus readily provided.

    摘要翻译： 在单个微室中依次进行核酸的浓缩和扩增的方法包括：将含核酸的样品和包含可变性盐的溶液引入具有亲水性内表面的微室中，以通过结合核酸来浓缩核酸 酸在微室的内表面上; 并通过向该室加入PCR混合物进行聚合酶链式反应（PCR）。 由于核酸可逆地结合到微室的内表面，与其中发生不可逆结合的氧化铝的表面相比，PCR产率更高。 此外，所有过程都在单个微室中顺序进行，以便可以减少样品数量，消耗品，时间和处理和分析的劳动力，可以提高检测灵敏度，并且样品交叉污染的风险在没有样品时显着降低 通过消除样品的运输而损失。 因此容易提供用于浓缩和扩增核酸的完整的自动化系统。

    METHOD AND APPARATUS FOR PURIFYING NUCLEIC ACID ON HYDROPHILIC SURFACE OF SOLID SUPPORT USING HYDROGEN BONDING
    5.
    发明申请
    METHOD AND APPARATUS FOR PURIFYING NUCLEIC ACID ON HYDROPHILIC SURFACE OF SOLID SUPPORT USING HYDROGEN BONDING 审中-公开
    使用氢键连接固体支持的亲水表面上的核酸的方法和装置

    公开(公告)号：US20070238109A1

    公开(公告)日：2007-10-11

    申请号：US11553657

    申请日：2006-10-27

    申请人： Jun-hong MIN ,  In-ho LEE ,  Chang-eun YOO ,  Ki-woong HAN ,  Young-rok KIM

    发明人： Jun-hong MIN ,  In-ho LEE ,  Chang-eun YOO ,  Ki-woong HAN ,  Young-rok KIM

    IPC分类号： C12Q1/68 ,  C12M3/00

    CPC分类号： C12N15/1006 ,  C12N15/1003

    摘要： Provided is a method of purifying nucleic acid, the method including: contacting a nucleic acid-containing sample and a solution containing a kosmotropic salt on a solid support having a hydrophilic functional group on its surface to bind the nucleic acid to the solid support. Since the solid support is used as it is without any surface treatment, manufacture of the apparatus is very easy, and nucleic acid can be bound to the solid support without specific additives in a wide pH range, so that the apparatus can be used for a Lab-On-a-Chip.

    摘要翻译： 提供了一种纯化核酸的方法，所述方法包括：使含核酸的样品和含有可变色盐的溶液在其表面上具有亲水性官能团的固体支持物上接触，以将核酸结合到固体支持物上。 由于固体支持物原样使用而没有进行任何表面处理，所以装置的制造非常容易，并且核酸可以在宽的pH范围内结合固体支持物而没有特定的添加剂，使得该装置可以用于 实验室芯片

    METHOD OF MANUFACTURING GAS SENSOR USING METAL LIGAND AND CARBON NANOTUBES
    8.
    发明申请
    METHOD OF MANUFACTURING GAS SENSOR USING METAL LIGAND AND CARBON NANOTUBES 审中-公开
    使用金属配体和碳纳米管制造气体传感器的方法

    公开(公告)号：US20080095922A1

    公开(公告)日：2008-04-24

    申请号：US11750449

    申请日：2007-05-18

    申请人： Sung-ouk JUNG ,  Soo-suk LEE ,  In-ho LEE ,  Hun-joo LEE

    发明人： Sung-ouk JUNG ,  Soo-suk LEE ,  In-ho LEE ,  Hun-joo LEE

    IPC分类号： B05D3/02 ,  B05D3/00

    CPC分类号： G01N27/127 ,  B82Y15/00

    摘要： A method of manufacturing a gas sensor includes using a metal ligand and carbon nanotubes (“CNTs”). The method includes forming electrodes on a substrate, coating a paste, in which the metal ligand including a metal having adsorption selectivity with respect to at least one specific gas and carbon nanotubes (“CNTs”) are mixed, on the substrate on which the electrodes are formed, and reducing the metal ligand in the paste.

    摘要翻译： 制造气体传感器的方法包括使用金属配体和碳纳米管（“CNT”）。 该方法包括在基板上形成电极，涂覆糊料，其中将金属配体包括相对于至少一种特定气体和碳纳米管（“CNT”）具有吸附选择性的金属混合在其上，其中电极 并且还原糊中的金属配体。

    ELECTRODIALYSIS APPARATUS AND ELECTRODIALYSIS METHOD USING THE SAME
    9.
    发明申请
    ELECTRODIALYSIS APPARATUS AND ELECTRODIALYSIS METHOD USING THE SAME 有权
    电化学装置和使用该方法的电解方法

    公开(公告)号：US20080073214A1

    公开(公告)日：2008-03-27

    申请号：US11737448

    申请日：2007-04-19

    申请人： Hun-joo LEE ,  Soo-suk LEE ,  Joon-ho KIM ,  Sung-ouk JUNG ,  In-ho LEE

    发明人： Hun-joo LEE ,  Soo-suk LEE ,  Joon-ho KIM ,  Sung-ouk JUNG ,  In-ho LEE

    IPC分类号： B01J47/00 ,  C02F1/42 ,  C02F1/469

    CPC分类号： B01D61/422 ,  B01D2311/243 ,  B01D2313/02 ,  B01D2313/10 ,  B01D2313/26 ,  B01D2313/30 ,  B01D2313/50 ,  B01D2321/185

    摘要： An electrodialysis apparatus includes a sample chamber including first and second dialysis membranes and filled with a sample between the first dialysis membrane and the second dialysis membrane, an anode chamber including an anode and filled with a first chamber solution between the anode and the first dialysis membrane, and a cathode chamber including a cathode and filled with a second chamber solution between the cathode and the second dialysis membrane. In particular, when a voltage is applied to the anode and the cathode, ionic materials of the sample move to the anode and cathode chambers.

    摘要翻译： 电渗析装置包括：样品室，包括第一和第二透析膜，并在第一透析膜和第二透析膜之间填充样品;阳极室，包括阳极，并在阳极和第一透析膜之间填充第一室溶液 以及包括阴极并在阴极和第二透析膜之间填充有第二室溶液的阴极室。 特别地，当向阳极和阴极施加电压时，样品的离子材料移动到阳极室和阴极室。