Method of monitoring health status of a patient

    公开(公告)号:US11241179B2

    公开(公告)日:2022-02-08

    申请号:US15063377

    申请日:2016-03-07

    申请人: TheraNova, LLC

    发明人: Daniel R. Burnett

    摘要: Foley type catheter embodiments for sensing physiologic data from a urinary tract of a patient are disclosed. The system includes the catheter and a data processing apparatus and methods for sensing physiologic data from the urinary tract. Embodiments may also include a pressure sensor having a pressure interface at a distal end of the catheter, a pressure transducer at a proximal end, and a fluid column disposed between the pressure interface and transducer. When the distal end is residing in the bladder, the pressure transducer can transduce pressure impinging on it into a chronological pressure profile, which can be processed by the data processing apparatus into one or more distinct physiologic pressure profiles, for example, peritoneal pressure, respiratory rate, and cardiac rate. At a sufficiently high data-sampling rate, these physiologic data may further include relative pulmonary tidal volume, cardiac output, relative cardiac output, and absolute cardiac stroke volume.

    Methods and devices for the diagnosis and treatment of diabetes

    公开(公告)号:US10143408B2

    公开(公告)日:2018-12-04

    申请号:US15451155

    申请日:2017-03-06

    申请人: TheraNova, LLC

    摘要: Methods and devices for the diagnosis and treatment of diabetes are disclosed in which an analyte concentration within a peritoneal fluid of a human subject may be determined by implanting an analyte sensor apparatus in the subject where the apparatus may comprise a housing and a flexible sensing catheter which has a lumen with a plurality of apertures and an exterior surface with an analyte sensor affixed thereto. The catheter may comprise a proximal end attached to the housing and the remaining end may be positioned freely within the peritoneal space to contact peritoneal fluid where an analyte concentration in the peritoneal fluid may be sensed. The housing may be anchored at a subcutaneous site proximate the peritoneal space. The sensed analyte concentration may then be transduced into a transmittable electrical signal.

    Devices and methods to measure gastric residual volume

    公开(公告)号:US11284832B2

    公开(公告)日:2022-03-29

    申请号:US15222670

    申请日:2016-07-28

    申请人: TheraNova, LLC

    摘要: Devices and methods to measure gastric residual volume (GRV) are described where at least one additive component (a GRV indicator) may be dispersed in a body lumen such as a stomach. The GRV indicator may changes a physical (chemical, electrical, thermal, mechanical, optical, etc.) characteristic within the stomach by a measureable degree. This degree of change and/or the rate of return to the previous state, may be used to determine the GRV of a patient. The determined GRV can also be used to automatically or semi-automatically control the patient's feeding rate and/or volume and/or frequency to adequately nourish the patient but avoid complications. The physical characteristic(s) may also be used to detect that the feeding catheter or tube is in the correct location (ie stomach vs lung or esophagus.