摘要:
A viral vector for the integration and expression of at least one heterologous gene in fowl pest cells consists wholly or in part of the proviral genome of fowl pest erythroblastosis or of a related virus in which said heterologous gene(s) replace(s) the v-erbA gene and/or the v-erB gene. Said gene(s) is(are) controlled either by an LTR promoter of the same virus, in which case the heterologous gene(s); mimics(s) the gene(s) it(they) replace, or by a heterologous promoter, in which case the additional att sequence is situated upstream of said heterologous promoter.
摘要:
The invention relates to a virus for cloning or expression of a foreign gene, characterized in that it consists of all or part of the genome of avian erythroblastosis virus and contains at least one foreign gene situated between the 3 LTR sequences.
摘要:
An instrument kit is provided for reaming bone around a head of a bone, the bone including an implanted epiphysis component. The instrument kit includes a reaming guide and a reamer. The reaming guide is couplable to the epiphysis component and has a first reamer support feature and a second reamer support feature. The reamer is couplable to one of the first reamer support feature and the second support feature to ream bone around the epiphysis component.
摘要:
The invention relates to a modular humeral prosthesis for an inverse shoulder prosthesis, comprising an anatomical shaft (1) and a separable epiphyseal head (2) which may be angularly orientated by rotation about the longitudinal axis (XX) of the anatomical shaft. The anatomical shaft and the epiphyseal head comprise complementary angular indexing means (11, 28) for relative rotational fixation.
摘要:
An instrument kit is provided for reaming bone around a head of a bone, the bone including an implanted epiphysis component. The instrument kit includes a reaming guide and a reamer. The reaming guide is couplable to the epiphysis component and has a first reamer support feature and a second reamer support feature. The reamer is couplable to one of the first reamer support feature and the second support feature to ream bone around the epiphysis component.
摘要:
A stemless humeral component for replacing the humeral head of a patient's humerus includes a support flange having a number of cantilevered legs extending distally away from a bottom surface thereof. Instruments and methods for surgically installing the stemless humeral component are also disclosed.
摘要:
The present invention relates to the activation of the protein synthesis by controlling the post-transcriptional steps of mRNA translation into proteins. A polypeptide is provided, which is capable of activating said protein translation. The principal industrial application of the invention is the control of recombinant protein production in cultured cells including in bioreactors.
摘要:
An alignment system for aligning a reaming guide during insertion into a cavity of a bone is provided. The bone has a resected surface and the cavity defines a cavity axis. The system includes a reaming guide that includes an elongate stem portion having a stem axis, a neck portion extending from the stem portion at an incline with respect to the stem axis, and an alignment instrument. The alignment instrument includes a handle defining a handle axis, the handle being releasably couplable to the reaming guide such that the handle axis is in a predetermined relationship with the stem axis. The alignment instrument further comprises a plane finder slidably coupled to the handle, the plane finder comprising a surface defined by a plane that intersects the axis of the handle at an angle having a predetermined relationship with the angle at which a resection surface of the bone intersects the cavity axis.
摘要:
An instrument kit for reaming a cavity within a resected head of a bone is provided. The kit includes a reaming guide, at least two adaptor sleeves and a reamer. The reaming guide includes an elongate stem portion insertable into a cavity extending into the bone from a resection surface at the head of the bone and a neck portion. The at least two adapter sleeves are mountable upon the reaming guide. Each adapter sleeve has a longitudinal axis, being generally cylindrical and a bore configured to receive part of the neck portion of the reaming guide. When the adapter sleeve is mounted upon the neck portion of a reaming guide inserted into a cavity in a bone the reamer is arranged to ream a cavity into the resection surface of the bone around the neck portion.
摘要:
A humeral component of a reverse shoulder prosthesis includes a stem part configured for location within the intramedullary cavity of the humerus, the stem part having a stem axis, an epiphyseal part connected to the elongate stem part and having a concave bearing surface defining an epiphyseal axis, and wherein the epiphyseal axis is offset posteriorly relative to the stem axis.