Coating media, the use thereof, and a method of producing multilayer
coatings
    3.
    发明授权
    Coating media, the use thereof, and a method of producing multilayer coatings 失效
    涂布介质及其用途以及多层涂料的制造方法

    公开(公告)号:US6063448A

    公开(公告)日:2000-05-16

    申请号:US981644

    申请日:1998-03-09

    摘要: A coating medium suitable for multilayer coatings, containing, as a binder vehicle:______________________________________ A) 10 to 90% by weight of one or more hydroxy-functional (meth)acrylic copolymers, obtained from a1) 20 to 40% by weight of hydroxyalkyl esters of (meth)acrylic acid a2) 10 to 30% by weight of non-functionalised (meth) acrylates a3) 0 to 5% by weight of unsaturated carboyxlic acids a4) 10 to 60% by weight of non-functionalised monomers a5) 0 to 15% by weight of amino-functional monomers, and a6) 0 to 5% by weight of multiply-unsaturated monomers B) 90 to 10% by weight of hydroxy-functional polyesters, C) 0 to 40% by weight of hydroxy-functional binder vehicles D) 5 to 50% by weight of blocked polyisocyanates, E) 5 to 40% by weight of components based on triazine which crosslink with the hydroxyl groups of components A), B) and C) with the formation of ether and/or ester groups, ______________________________________ wherein at least 50% by weight of the (meth)acrylic copolymers, with respect to the total amount of component A), has been produced in the presence of the hydroxy-functional polyesters corresponding to at least 20% by weight of the total amount of component B).

    摘要翻译: PCT No.PCT / EP96 / 02944 Sec。 371日期1998年3月9日 102(e)1998年3月9日PCT PCT 1996年7月4日PCT公布。 公开号WO97 / 03102 日期1997年1月30日适用于多层涂料的涂料介质,其含有作为粘合剂的载体:A)10-90重量%的一种或多种羟基官能 - (甲基)丙烯酸共聚物,其由-a1)20至 40重量%的(甲基)丙烯酸的羟基烷基酯a2)10-30重量%的非官能化(甲基)丙烯酸酯-a3)0-5重量%的不饱和羧酸-a4)10至60重量% 的非官能化单体a5)0-15%(重量)的氨基官能单体和-16)0-5%重量的多不饱和单体B)90-10%重量的羟基官能化单体 聚酯,-C)0-40%(重量)的羟基官能粘合剂载体-D)5-50%重量的封端多异氰酸酯, - E)5-40%(重量)基于与三羟基交联的三嗪组分 组分A),B)和C)与形成醚和/或酯基 - 其中至少50重量%的(甲基)丙烯酸共聚物相对于 相对于组分A)的总量已经在对应于组分B)总量的至少20重量%的羟基官能聚酯的存在下生产。

    Binder composition, coating compositions containing this binder
composition, production and use thereof
    4.
    发明授权
    Binder composition, coating compositions containing this binder composition, production and use thereof 失效
    粘合剂组合物,含有该粘合剂组合物的涂料组合物,其生产和使用

    公开(公告)号:US5739216A

    公开(公告)日:1998-04-14

    申请号:US732474

    申请日:1997-01-02

    摘要: Binder composition, coating compositions produced therefrom and use thereof, in particular for multi-layer lacquer coatings. The binder composition contains: A) 25 to 75 wt. % of the reaction product of one or more carboxy-functionalised (meth) acrylic copolymers containing urethane groups and/or of one or more carboxy-functionalised polyesters containing urethane groups, each having an acid value of 30 to 200 mg of KOH/g, with one or more lactones, B) 25 to 75 wt. % of one or more epoxy-functionalised crosslinking agents having at least two epoxy functions per molecule with a number average molecular weight (Mn) of 200 to 10000 g/mol, C) 0 to 60 wt. % of one or more polyols having at least two hydroxyl functions per molecule, D.sub.1) 0 to 20 wt. % of one or more melamine resins, D.sub.2) 0 to 40 wt. % of one or more free or capped polyisocyanates, wherein the sum of the weight percentages of components A), B), C), D.sub.1) and D.sub.2) amounts to 100 wt. %, together with E) 0 to 10 wt. % of one or more catalysts to catalyse the reaction of carboxyl and epoxy groups, relative to the sum of weights of components A) to D.sub.2).

    摘要翻译: PCT No.PCT / EP95 / 01663 Sec。 371日期1997年1月2日 102(e)日期1997年1月2日PCT提交1995年5月3日PCT公布。 出版物WO95 / 30719 日期1995年11月16日粘合剂组合物,由其制备的涂料组合物及其用途,特别是多层漆涂料。 粘合剂组合物含有:A)25〜75wt。 含有氨基甲酸酯基团的一种或多种羧基官能化(甲基)丙烯酸共聚物和/或含有氨基甲酸酯基团的一种或多种羧基官能化聚酯的反应产物的百分比,其酸值为30-200mg KOH / g, 与一种或多种内酯,B)25至75wt。 %的一种或多种环氧官能化交联剂,每分子具有至少两个环氧官能团,数均分子量(Mn)为200至10000g / mol,C)0至60wt。 %的一种或多种每分子具有至少两个羟基官能团的多元醇,D1)0-20重量% %的一种或多种三聚氰胺树脂,D2)0-40重量% %的一种或多种游离或封端的多异氰酸酯,其中组分A),B),C),D1)和D2的重量百分比之和相当于100wt。 %,连同E)0〜10wt。 %的一种或多种催化剂以催化羧基和环氧基团的反应,相对于组分A)至D2的重量之和)。

    Binder agent composition, coating agents containing them, their production and use
    5.
    发明授权
    Binder agent composition, coating agents containing them, their production and use 失效
    粘合剂组合物,含有它们的包衣剂,其生产和使用

    公开(公告)号:US06258874B1

    公开(公告)日:2001-07-10

    申请号:US09331098

    申请日:1999-06-14

    IPC分类号: C08L6300

    摘要: This invention relates to a binder composition suitable for coating compositions, which binder composition contains one or more carboxy-functional polymers, one or more compounds having an epoxide function in the molecule, one or more polyols having at least two hydroxyl functions in the molecule, which polyols differ from a component A) optionally containing hydroxyl functions, components which crosslink with hydroxyl groups to form ethers and/or a triazine-based crosslinking agent, optionally one or more polyisocyanates, which may optionally be capped, optionally an anhydride component and optionally one or more catalysts for catalysing the reaction of carboxyl and epoxide groups.

    摘要翻译: 本发明涉及适用于涂料组合物的粘合剂组合物,该粘合剂组合物含有一种或多种羧基官能聚合物,一种或多种在分子中具有环氧官能团的化合物,一种或多种在分子中具有至少两个羟基官能团的多元醇, 哪些多元醇不同于任选地含有羟基官能团的组分A),与羟基交联以形成醚和/或三嗪基交联剂的组分,任选的一种或多种多异氰酸酯,其可任选地被封端,任选地含有酸酐组分, 用于催化羧基和环氧基反应的一种或多种催化剂。

    Coating agent, the manufacture and uses thereof
    7.
    发明授权
    Coating agent, the manufacture and uses thereof 失效
    涂布剂,其制造和用途

    公开(公告)号:US06200639B1

    公开(公告)日:2001-03-13

    申请号:US09319957

    申请日:1999-06-14

    IPC分类号: C09D13302

    摘要: Coating composition suitable for multi-layer lacquerings, with a binder composition which comprises: A) 25 to 75 wt. % of carboxyl-functional (meth)acrylic copolymers and/or carboxyl-functional polyesters, the carboxyl functionality of which corresponds to an acid number of 15 to 300 mg KOH/g, B) 25 to 75 wt. % of epoxide-functionalized crosslinker resins, at least one of which is a (meth)acrylic copolymer which has been prepared co-using tert-butyl (meth)acrylate, C) 0 to 50 wt. % of polyols which have at least two hydroxyl functions in the molecule, D) 0 to 40 wt. % of components which crosslink with hydroxyl groups to form ethers, and/or of a crosslinking agent based on triazine, E) 0 to 40 wt. % of polyisocyanates, F) 0 to 50 wt. % of at least one organic polyanhydride with at least two cyclic carboxylic acid anhydride groups per molecule, G) 0 to 20 wt. % of reactive thinners with an epoxide function, H) 0 to 10 wt. % of one or more catalysts for the reaction of carboxyl and epoxide groups.

    摘要翻译: 适用于多层漆的涂料组合物,其粘合剂组合物包含:A)25至75wt。 %的羧基官能(甲基)丙烯酸共聚物和/或羧基官能聚酯,其羧基官能度相当于酸值为15-300mg KOH / g,B)25-75wt。 %的环氧官能化交联剂树脂,其中至少一种是(甲基)丙烯酸共聚物,其与(甲基)丙烯酸叔丁酯共同制备,C)0至50重量% %的分子中具有至少两个羟基官能团的多元醇,D)0-40重量% %的与羟基交联以形成醚的组分,和/或基于三嗪的交联剂,E)0至40重量% %的多异氰酸酯,F)0至50重量% %的至少一种每分子具有至少两个环状羧酸酐基团的有机聚酐,G)0-20重量% %的具有环氧官能团的反应性稀释剂,H)0至10wt。 %的一种或多种用于羧基和环氧基反应的催化剂。

    Binder composition, coating composition containing this binder,
production and use thereof
    8.
    发明授权
    Binder composition, coating composition containing this binder, production and use thereof 失效
    粘合剂组合物,含有这种粘合剂的涂料组合物的生产和使用

    公开(公告)号:US5686532A

    公开(公告)日:1997-11-11

    申请号:US491145

    申请日:1995-06-16

    摘要: A binder composition, a coating composition containing this binder, a process for its production and use to produce single or multi-layer lacquer coatings, particularly in the automotive sector, are described. The binder composition contains A) 25 to 75 wt. % of the reaction product of one or more carboxy-functionalised poly(meth)acrylic copolymers and/or one or more carboxy-functionalised polyesters, each with an acid value of 15 to 200 mg KOH/g, with one or more lactones, B) 25 to 75 wt. % of one or more epoxy-functionalised crosslinking agents with at least two epoxy functional groups per molecule, with a number average molecular weight (Mn) of 200 to 10000 g/mol, C) 0 to 60 wt. % of one or more polyols with at least two hydroxyl functional groups per molecule, D.sub.1) 0 to 20 wt. % of one or more melamine resins, D.sub.2) 0 to 40 wt. % of one or more capped polyisocyanates, wherein the sum of the weight percentages of components A), B), C), D.sub.1) and D.sub.2) is 100 wt. %, together with E) 0 to 10 wt. % of one or more catalysts to catalyse the reaction of the carboxyl and epoxy groups, related to the sum of the weights of components A) to D.sub.2).

    摘要翻译: 描述了粘合剂组合物,含有该粘合剂的涂料组合物,其生产和用于生产单层或多层漆涂料的方法,特别是在汽车领域。 粘合剂组合物含有A)25〜75wt。 一种或多种羧基官能化的聚(甲基)丙烯酸共聚物和/或一种或多种羧酸官能化聚酯的反应产物(各自具有15至200mg KOH / g酸值)与一种或多种内酯B )25〜75重量% %的一种或多种环氧官能化交联剂,每分子具有至少两个环氧官能团,数均分子量(Mn)为200至10000g / mol,C)0至60wt。 %的一种或多种每分子具有至少两个羟基官能团的多元醇,D1)0-20重量% %的一种或多种三聚氰胺树脂,D2)0-40重量% %的一种或多种封端的多异氰酸酯,其中组分A),B),C),D1)和D2的重量百分比之和为100重量%。 %,连同E)0〜10wt。 %的一种或多种催化剂来催化羧基和环氧基的反应,与组分A)至D2的重量之和有关)。

    METHOD FOR IDENTIFYING CELL-SPECIFIC PROTEIN COMBINATION PATTERNS
    10.
    发明申请
    METHOD FOR IDENTIFYING CELL-SPECIFIC PROTEIN COMBINATION PATTERNS 审中-公开
    识别细胞特异性蛋白质组合模式的方法

    公开(公告)号:US20090305308A1

    公开(公告)日:2009-12-10

    申请号:US11909357

    申请日:2006-03-21

    申请人: Walter Schubert

    发明人: Walter Schubert

    摘要: The present invention discloses a method for identifying cell-specific protein combination patterns of cell surfaces of circulating cells of the immune system of a human or animal for the identification of different stages of organ-specific chronic inflammatory diseases or tumour diseases comprising the following steps: a) providing a sample of circulating cells of the immune system of a human or animal showing an organ-specific chronic inflammatory disease or tumour disease and providing a sample of circulating cells of the same cell type of the immune system of a healthy human or animal; b) determining cell-specific protein combination patterns of the cell surfaces of said healthy and pathologically modified cells; c) comparing the resulting protein combination patterns of the cell surfaces of said healthy and pathologically modified cells and subtracting the coincident parts of the protein combination patterns of said healthy and pathologically modified cells, thereby determining a cell-specific protein combination patterns of the cell surfaces of said pathologically modified cells resulting therefrom; and d) identifying and characterizing the resulting cell-specific protein combination pattern of the cell surfaces of said pathologically modified circulating cells of the immune system in terms of molecules and its spatial arrangement within the cell as disease specific. The invention moreover relates to compositions and kits comprising antibodies and/or ligands which can be employed for the performance of the method.

    摘要翻译: 本发明公开了一种用于鉴定人或动物免疫系统的循环细胞的细胞表面的细胞特异性蛋白质组合模式以识别器官特异性慢性炎性疾病或肿瘤疾病的不同阶段的方法,包括以下步骤: a)提供显示器官特异性慢性炎性疾病或肿瘤疾病的人或动物的免疫系统的循环细胞样品,并提供健康人或动物免疫系统相同细胞类型的循环细胞样品 ; b)确定所述健康和病理修饰的细胞的细胞表面的细胞特异性蛋白质组合模式; c)比较所得健康和病理修饰细胞的细胞表面的所得蛋白质组合模式,并减去所述健康和病理修饰细胞的蛋白质组合模式的重合部分,由此确定细胞表面的细胞特异性蛋白质组合模式 由此产生的所述病理修饰细胞; 和d)根据分子及其在细胞内的空间排列作为疾病特异性,鉴定和表征所述免疫系统的所述病理修饰的循环细胞的细胞表面的细胞特异性蛋白质组合模式。 本发明还涉及可用于实施该方法的抗体和/或配体的组合物和试剂盒。