摘要:
The present invention aims to provide a corneal endothelium cell proliferation accelerator and a therapeutic agent for a disease relating to corneal endothelium damage, which are administered into the anterior chamber. bFGF is released in a sustained manner by forming bFGF sustained-release gelatin hydrogel particles wherein bFGF is carried on gelatin hydrogel. Therefore, the proliferation of corneal endothelium cells can be accelerated persistently by administration of a preparation containing the bFGF sustained-release gelatin hydrogel particles into the anterior chamber, and diseases relating to corneal endothelium damage can be treated.
摘要:
The present invention aims to provide a corneal endothelium cell proliferation accelerator and a therapeutic agent for a disease relating to corneal endothelium damage, which are administered into the anterior chamber. bFGF is released in a sustained manner by forming bFGF sustained-release gelatin hydrogel particles wherein bFGF is carried on gelatin hydrogel. Therefore, the proliferation of corneal endothelium cells can be accelerated persistently by administration of a preparation containing the bFGF sustained-release gelatin hydrogel particles into the anterior chamber, and diseases relating to corneal endothelium damage can be treated.
摘要:
The present invention provides a graft more suitable for the transplantation of corneal endothelial cells and an application method thereof. Specifically, the present invention provides a corneal endothelial preparation capable of cell proliferation in vivo, which contains a substrate and a corneal endothelial cell layer cultured on the substrate, and a treatment method of a disease selected from the group consisting of bullous keratopathy, corneal edema, corneal leukoma and corneal endothelial inflammation, which includes a step of transplanting the preparation to patients. As the substrate, collagen is used.
摘要:
The present invention provides a graft more suitable for the transplantation of corneal endothelial cells and an application method thereof. Specifically, the present invention provides a corneal endothelial preparation capable of cell proliferation in vivo, which contains a substrate and a corneal endothelial cell layer cultured on the substrate, and a treatment method of a disease selected from the group consisting of bullous keratopathy, corneal edema, corneal leukoma and corneal endothelial inflammation, which includes a step of transplanting the preparation to patients. As the substrate, collagen is used.
摘要:
The present invention aims to provide a means for effectively and conveniently treating diseases wherein corneal endothelial cells poor in proliferative capacity in vivo are damaged. The present invention provides a therapeutic agent for corneal endothelial dysfunction containing (R)-(+)-N-(1H-pyrrolo [2,3-b]pyridin-4-yl)-4-(1-aminoethyl)benzamide or a pharmacologically acceptable salt thereof (compound (Ia)) as active ingredient, an agent for promoting adhesion of corneal endothelial cells, containing compound (Ia), a culture medium for corneal endothelial cells, containing the agent for promoting adhesion, an implant for corneal endothelial keratoplasty, containing corneal endothelial cells, scaffold and compound (Ia), and a production method of a corneal endothelial preparation, including a step of cultivating corneal endothelial cells using the culture medium.
摘要:
An endoscopic treatment system 1 of the present invention includes an overtube 2 that is inserted into the body of a patient. An endoscope 7 and a suturing device 8 are inserted into the overtube 2. The overtube 2 has a long and flexible tube main body 3, and a chamber 4 is provided at the distal end of the tube main body 3. The chamber 4 has a lateral hole 10 formed on the lateral surface thereof. The width of the lateral hole 10 is set such that a lesion can be drawn into the lateral hole 10 while preventing other organs on the periphery of the lesion from being drawn into the lateral hole 10.
摘要:
An endoscope includes a side viewing observation section and a forward viewing observation section provided on a distal end side of an insertion portion which is inserted into an observation target for acquiring subject images of an observation target in a circumferential direction and an insertion direction of the insertion portion, respectively, a shielding section located within a viewing field of the side viewing observation section for shielding light from the subject entering the side viewing observation section and a protruding member protruding from the insertion portion arranged in a shielding region formed by the shielding section. The protruding member includes at least a cleaning nozzle for cleaning the forward viewing observation section and/or the side viewing observation section.
摘要:
In an endoscopic treatment instrument having a plurality of sheaths, a supporting member for directly and indirectly supporting the plurality of sheaths, and a connecting member for directly/indirectly bringing the sheaths and an endoscope in a connected state are provided. The supporting member constrains a relative position of the plurality of sheaths and the connecting member can change the connecting state. Therefore, when an operator changes the connecting state of the connecting member, the positional relation of the endoscope and the plurality of sheaths can be changed, while the positional relation of the plurality of sheaths is still constrained. Accordingly, for example, left and right sheaths can be easily exchanged.
摘要:
This is a device for supporting an animal clamp (100) fixing a small laboratory animal in a specified position with respect to a testing apparatus (300). A base board (2) is fixed to the testing apparatus (300). An elevating board (4) is raised or lowered by jacks (31, 32) installed between it and base board (2), and a clamp mounting board (8) is tilted by jack (61) and sliding member (62) installed between it and elevating board (4).As a result, the height position and inclination angle of the animal clamp (100) mounted on the clamp mounting board (8) are determined, and they may be finely adjusted by properly manipulating the jacks (31, 32, 61). The animal clamp (100) does not slip off the clamp mounting board (8) because of the clamp slip preventive flange piece (7).
摘要:
A communication system including a plurality of portable terminal apparatuses each capable of calling a partner terminal apparatus via a radio channel and a plurality of fixed terminal apparatuses each being connected via an ISDN interface to a time-division switch and each being connectable to the portable terminal in which when two portable terminals having an established cell are respectively attached to two fixed terminal apparatuses arbitrarily selected, the state of the call is automatically transferred to the two fixed terminal apparatuses so that the speech can be achieved between the fixed terminal apparatuses without conducting another call establishing procedure.