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公开(公告)号:US5270196A
公开(公告)日:1993-12-14
申请号:US827252
申请日:1992-01-29
申请人: Yosuke Sawada , Tomokazu Ueki , Satoshi Yamamoto , Koji Tomita , Yasuo Fukagawa , Toshikazu Oki
发明人: Yosuke Sawada , Tomokazu Ueki , Satoshi Yamamoto , Koji Tomita , Yasuo Fukagawa , Toshikazu Oki
CPC分类号: B82Y5/00 , A61K47/48 , A61K47/48761 , C12N9/16 , C12R1/465 , Y10S435/886
摘要: The present invention relates to an arylsulfatase of microbial origin. The enzyme may be linked to an antibody against a tumor-associated antigen and the resulting conjugate used in conjuction with a sulfated prodrug of a 4'-demethylepipodophyllotoxin glucoside derivative, particularly etoposide in cancer chemotherapy.
摘要翻译: 本发明涉及微生物来源的芳基硫酸酯酶。 该酶可以与针对肿瘤相关抗原的抗体连接,所得到的缀合物与4'-去甲表鬼臼毒素葡糖苷衍生物的硫酸化前药结合使用,特别是癌症化学疗法中依托泊苷。
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公开(公告)号:US11167637B2
公开(公告)日:2021-11-09
申请号:US14390693
申请日:2012-04-12
申请人: Satoshi Yamamoto , Chiaki Kataoka , Masaki Akagi
发明人: Satoshi Yamamoto , Chiaki Kataoka , Masaki Akagi
IPC分类号: B60K15/04
摘要: To obtain a fuel filler structure for a fuel tank wherein when causing an opening and closing valve to close, it can be ensured that the opening and closing valve does not rapidly rotate to a closed position in which it closes a fuel fill inlet, and when causing the opening and closing valve to open, the opening and closing valve can be opened with a small force. A fuel filler structure is equipped with a damper on the near side of a flapper valve in the insertion direction of a fuel nozzle. When the flapper valve rotates to an open position, the damper does not act on the flapper valve, and when the flapper valve rotates to a closed position, the damper acts on the flapper valve.
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公开(公告)号:US10534236B2
公开(公告)日:2020-01-14
申请号:US15737115
申请日:2016-06-17
申请人: Satoshi Yamamoto , Daisuke Goto , Toshiya Sagisaka , Masato Shinoda , Mamiko Inoue , Fuminari Kaneko , Tohru Yashiro
发明人: Satoshi Yamamoto , Daisuke Goto , Toshiya Sagisaka , Masato Shinoda , Mamiko Inoue , Fuminari Kaneko , Tohru Yashiro
IPC分类号: G02F1/15 , C07D265/28 , G09F9/30 , C09K9/02 , C08F20/36 , C07D265/38 , G02F1/1516
摘要: Provided is an electrochromic compound represented by the following general formula (I) or (II) where R1 to R13 are each independently a hydrogen atom, a halogen atom, a monovalent organic group, or a polymerizable functional group, and at least one of the R1 to the R13 is a polymerizable functional group.
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公开(公告)号:US09869918B2
公开(公告)日:2018-01-16
申请号:US14988992
申请日:2016-01-06
申请人: Takahiko Matsumoto , Keiichiroh Yutani , Hidekazu Yaginuma , Koh Fujimura , Fuminari Kaneko , Mamiko Inoue , Sukchan Kim , Satoshi Yamamoto , Tohru Yashiro
发明人: Takahiko Matsumoto , Keiichiroh Yutani , Hidekazu Yaginuma , Koh Fujimura , Fuminari Kaneko , Mamiko Inoue , Sukchan Kim , Satoshi Yamamoto , Tohru Yashiro
IPC分类号: G02F1/155 , G02F1/1343
CPC分类号: G02F1/155 , G02F1/13439 , G02F2001/1552
摘要: An electrochromic apparatus including a first support, a first electrode, a first transparent conductive layer, an electrochromic layer, a second support, a second electrode, a second transparent conductive layer, and an electrolyte layer is provided. The first and second supports have first and second surfaces, respectively, on each of which a plurality of grooves is formed. The grooves on the second surface are facing the grooves on the first surface. The first and second electrodes are disposed at each one of the plurality of grooves of the first and second supports, respectively. The first and second transparent conductive layers are in contact with the first and second surfaces, respectively. The electrochromic layer is in contact with the first transparent conductive layer. The electrolyte layer is between the electrochromic layer and the second transparent conductive layer.
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公开(公告)号:US09312036B2
公开(公告)日:2016-04-12
申请号:US13315887
申请日:2011-12-09
申请人: Yuki Minato , Toshihiro Yasuda , Kunihiko Kinugasa , Hajime Mori , Satoshi Yamamoto , Jun Suzuki , Tadahiro Mitsuhashi
发明人: Yuki Minato , Toshihiro Yasuda , Kunihiko Kinugasa , Hajime Mori , Satoshi Yamamoto , Jun Suzuki , Tadahiro Mitsuhashi
IPC分类号: G21C15/25 , F04F5/54 , G21C17/017 , G21C19/14 , G21C17/10
CPC分类号: G21C15/25 , F04F5/54 , G21C17/017 , G21C17/10 , G21C19/14 , Y02E30/40 , Y10T29/49735
摘要: In a jet pump measurement pipe repair method according to the present embodiment, a breakage part of a measurement pipe horizontally fixed to a lower part of a jet pump provided in reactor water in a reactor pressure vessel is repaired. The method has: a step of cutting and removing the measurement pipe including the breakage part; a step of retaining a connection pipe for connecting the remaining measurement pipe on the jet pump by means of a clamp; and a step of connecting ends of the remaining measurement pipe by means of the connection pipe.
摘要翻译: 在根据本实施例的喷射泵测量管道修复方法中,修复水平固定到设置在反应堆压力容器中的反应器水中的喷射泵的下部的测量管的断裂部分。 该方法具有:切断除去包含断裂部的测量管的步骤; 保持用于通过夹具连接喷射泵上的剩余测量管的连接管的步骤; 以及通过连接管连接剩余测量管的端部的步骤。
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公开(公告)号:US09291893B2
公开(公告)日:2016-03-22
申请号:US13281145
申请日:2011-10-25
CPC分类号: G03F7/0046 , G03F7/0045 , G03F7/0397 , G03F7/2041
摘要: A resist composition contains; a resin having a structural unit represented by the formula (aa) and a structural unit represented by the formula (ab); and an acid generator, wherein Raa1 represents a hydrogen atom and a methyl group; Aaa1 represents an optionally substituted C1 to C6 alkanediyl group etc.; Raa2 represents an optionally substituted C1 to C18 aliphatic hydrocarbon group; Rab1 represents a hydrogen atom and a methyl group; Aab1 represents a single bond, an optionally substituted C1 to C6 alkanediyl group etc.; W1 represents an optionally substituted C4 to C24 alicyclic hydrocarbon group; n represents 1 or 2; Aab2 in each occurrence independently represents an optionally substituted C1 to C6 aliphatic hydrocarbon group; Rab2 in each occurrence independently represents a C1 to C12 fluorinated alkyl group.
摘要翻译: 抗蚀剂组合物含有 具有由式(aa)表示的结构单元的树脂和由式(ab)表示的结构单元; 和酸产生剂,其中Raa1表示氢原子和甲基; Aaa1表示可以具有取代基的C1〜C6烷二基等。 Raa2表示任选取代的C1至C18脂族烃基; Rab1表示氢原子和甲基; Aab1表示单键,任选取代的C 1至C 6烷二基等; W1表示任选取代的C4至C24脂环族烃基; n表示1或2; Aab2各自独立地表示任选取代的C 1至C 6脂族烃基; Rab2各自独立地表示C1〜C12氟化烷基。
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公开(公告)号:US09229320B2
公开(公告)日:2016-01-05
申请号:US13196446
申请日:2011-08-02
申请人: Koji Ichikawa , Satoshi Yamamoto
发明人: Koji Ichikawa , Satoshi Yamamoto
CPC分类号: G03F7/0045 , G03F7/0046 , G03F7/0397 , G03F7/2041 , G03F7/2059
摘要: A resist composition contains; a resin having a structural unit derived from a compound represented by the formula (a); and an acid generator represented by the formula (B1). wherein R1 represents a hydrogen atom or a methyl group; A10 represents a single bond, an optionally substituted C1 to C6 alkanediyl group or a group represented by formula (a-1) defined in the specification; W1 represents an optionally substituted C4 to C36 alicyclic hydrocarbon group; A20 in each occurrence independently represents an optionally substituted C1 to C6 aliphatic hydrocarbon group; R2 in each occurrence independently represents a C1 to C12 perfluoroalkyl group; n represents 1 or 2; Q1 and Q2 independently represent a fluorine atom or a C1 to C6 perfluoroalkyl group; Lb1 represents an optionally substituted C1 to C17 divalent aliphatic hydrocarbon group; Y represents an optionally substituted C1 to C18 aliphatic hydrocarbon group; and Z+ represents an organic cation.
摘要翻译: 抗蚀剂组合物含有 具有衍生自由式(a)表示的化合物的结构单元的树脂; 和由式(B1)表示的酸发生剂。 其中R1表示氢原子或甲基; A10表示单键,可以具有取代基的C1〜C6烷二基或由说明书中定义的式(a-1)表示的基团; W1表示任选取代的C4至C36脂环族烃基; A20每次独立地表示任选取代的C 1至C 6脂族烃基; R2各自独立地表示C1〜C12全氟烷基; n表示1或2; Q1和Q2独立地表示氟原子或C1〜C6全氟烷基; Lb1表示任选取代的C 1至C 17二价脂族烃基; Y表示任选取代的C 1至C 18脂族烃基; Z +表示有机阳离子。
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公开(公告)号:US09224959B2
公开(公告)日:2015-12-29
申请号:US14172572
申请日:2014-02-04
申请人: Daisuke Goto , Satoshi Yamamoto , Toshiya Sagisaka , Takuji Kato , Takashi Okada , Masato Shinoda , Shinji Matsumoto , Masataka Mohri , Keiichiro Yutani
发明人: Daisuke Goto , Satoshi Yamamoto , Toshiya Sagisaka , Takuji Kato , Takashi Okada , Masato Shinoda , Shinji Matsumoto , Masataka Mohri , Keiichiro Yutani
IPC分类号: C07D495/02 , H01L51/00 , C07C1/213 , C07C15/20 , C07C15/24 , C07C15/28 , C07C15/38 , C07C15/56 , C07C15/58 , C07C15/60 , C07C17/093 , C07C17/10 , C07C17/361 , C07C25/22 , C07C69/013 , C07C69/18 , C07C69/63 , C07D321/00 , C07D409/14 , C07D495/04 , C07D495/06 , H01L51/05
CPC分类号: H01L51/0052 , C07C1/213 , C07C15/20 , C07C15/24 , C07C15/28 , C07C15/38 , C07C15/56 , C07C15/58 , C07C15/60 , C07C17/093 , C07C17/10 , C07C17/361 , C07C25/22 , C07C69/013 , C07C69/18 , C07C69/63 , C07C2602/10 , C07C2603/24 , C07C2603/44 , C07C2603/50 , C07C2603/52 , C07D321/00 , C07D409/14 , C07D495/04 , C07D495/06 , H01L51/0074 , H01L51/0558
摘要: A leaving substituent-containing compound including a partial structure represented by the following General Formula (I): where a pair of X1 and X2 or a pair of Y1 and Y2 each represent a hydrogen atom; the other pair each represent a group selected from the group consisting of a halogen atom and a substituted or unsubstituted acyloxy group having one or more carbon atoms; a pair of the acyloxy groups represented by the pair of X1 and X2 or the pair of Y1 and Y2 may be identical or different, or may be bonded together to form a ring; R1 to R4 each represent a hydrogen atom or a substituent; and Q1 and Q2 each represent a hydrogen atom, a halogen atom or a monovalent organic group, and may be bonded together to form a ring.
摘要翻译: 含有由以下通式(I)表示的部分结构的含有取代基的化合物:其中一对X1和X2或一对Y1和Y2各自表示氢原子; 另一对各自表示选自卤原子和具有一个或多个碳原子的取代或未取代的酰氧基的基团; 由一对X1和X2表示的一对酰氧基或一对Y1和Y2可以相同或不同,或者可以结合在一起形成环; R 1〜R 4各自表示氢原子或取代基; 并且Q1和Q2各自表示氢原子,卤素原子或一价有机基团,并且可以结合在一起形成环。
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公开(公告)号:US09156837B2
公开(公告)日:2015-10-13
申请号:US14235992
申请日:2012-07-27
申请人: Satoshi Yamamoto , Junya Shirai , Atsuko Ochida , Yoshiyuki Fukase , Yoshihide Tomata , Ayumu Sato , Shotaro Miura , Kazuko Yonemori , Ryokichi Koyama
发明人: Satoshi Yamamoto , Junya Shirai , Atsuko Ochida , Yoshiyuki Fukase , Yoshihide Tomata , Ayumu Sato , Shotaro Miura , Kazuko Yonemori , Ryokichi Koyama
IPC分类号: C07D277/30 , C07D277/56 , C07D211/90 , C07D417/12 , C07D471/04 , C07D401/12 , C07D277/24 , C07D401/04 , C07D417/04 , C07D417/14 , C07D491/107
CPC分类号: C07D471/04 , C07D417/04 , C07D417/14 , C07D491/107
摘要: A heterocyclic compound having an RORγt inhibitory activity, which is a compound of formula (I) or a salt thereof is provided. The compound has ring A, which is an optionally substituted cyclic group and is bound to a pyrazole ring though Q. Q is a bond, optionally substituted C1-10 alkylene, optionally substituted C2-10 alkenylene, or optionally substituted C2-10 alkynylene. R1 is a substituent. Ring B is a thiazole ring, an isothiazole ring or a dihydrothiazole ring, each of which is optionally further substituted by a substituent in addition to R2. R2 is an optionally substituted cyclyl-carbonyl-C1-6 alkyl group, an optionally substituted aminocarbonyl-C1-6 alkyl group, an optionally substituted cyclyl-C1-6 alkyl group, an optionally substituted cyclyl-C1-6 alkylamino-carbonyl group, an optionally substituted aminocarbonyl-C2-6 alkenyl group, an optionally substituted C1-6 alkylcarbonylamino-C1-6 alkyl group, an optionally substituted cyclyl-aminocarbonyl group, an optionally substituted cyclyl-carbonyl group or an optionally substituted non-aromatic heterocyclic group.
摘要翻译: 提供具有RORγt抑制活性的杂环化合物,其为式(I)化合物或其盐。 该化合物具有环A,其为任选取代的环状基团,并且通过Q键合至吡唑环。Q为键,任选取代的C 1-10亚烷基,任选取代的C 2-10亚烯基或任选取代的C 2-10亚炔基。 R1是取代基。 环B是噻唑环,异噻唑环或二氢噻唑环,除了R2之外,它们各自任选进一步被取代基取代。 R 2是任选取代的环羰基-C 1-6烷基,任选取代的氨基羰基-C 1-6烷基,任选取代的环C 1-6烷基,任选取代的环C 1-6烷基氨基羰基, 任选取代的氨基羰基-C 2-6烯基,任选取代的C 1-6烷基羰基氨基-C 1-6烷基,任选取代的环 - 氨基羰基,任选取代的环羰基或任选取代的非芳族杂环基。
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公开(公告)号:US09027764B2
公开(公告)日:2015-05-12
申请号:US13256671
申请日:2010-03-01
IPC分类号: B01D39/00 , B01D69/02 , B01D69/10 , B01D69/12 , B01D71/54 , B32B27/12 , B32B27/32 , B32B27/40 , B01D71/36 , F28D21/00 , F28F21/06
CPC分类号: B01D69/02 , B01D69/10 , B01D69/12 , B01D71/36 , B01D71/54 , B01D2325/40 , B32B5/022 , B32B5/024 , B32B5/026 , B32B27/12 , B32B27/285 , B32B27/306 , B32B27/308 , B32B27/322 , B32B27/40 , B32B2307/3065 , B32B2307/718 , B32B2307/724 , B32B2307/732 , F28D21/0015 , F28F21/06
摘要: A moisture-permeable separating membrane material includes a porous fluororesin membrane, a continuous moisture-permeable resin layer formed on the surface of the porous fluororesin membrane, and a textile layer for reinforcing the porous fluororesin membrane and the continuous moisture-permeable resin layer. The textile layer contains a flame retardant in the inside of each fiber and the surface of each fiber has been treated with a flame retardant. The moisture-permeable separating membrane material makes it possible to improve flame retardancy without deteriorating heat exchange characteristics.
摘要翻译: 透湿分离膜材料包括多孔氟树脂膜,形成在多孔氟树脂膜表面上的连续透湿树脂层和用于增强多孔氟树脂膜和连续透湿树脂层的织物层。 纺织层在每根纤维的内部含有阻燃剂,并且每种纤维的表面已用阻燃剂处理。 透湿分离膜材料可以在不降低热交换特性的情况下改善阻燃性。
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