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    Cell Growth Inhibiting Film, Medical Instrument and Digestive System Stent
    5.
    发明申请
    Cell Growth Inhibiting Film, Medical Instrument and Digestive System Stent 审中-公开
    细胞生长抑制膜，医疗器械和消化系统支架

    公开(公告)号：US20070275156A1

    公开(公告)日：2007-11-29

    申请号：US10580648

    申请日：2004-11-26

    申请人： Masaru Tanaka ,  Masatsugu Shimomura ,  Yoshihide Toyokawa

    发明人： Masaru Tanaka ,  Masatsugu Shimomura ,  Yoshihide Toyokawa

    IPC分类号： A61L31/00 ,  A61L27/00

    CPC分类号： A61L31/146

    摘要： A cell growth inhibiting film including a resin and having a porous structure formed at least on its surface, a cell growth inhibiting method including causing the surface of a film including a resin and having a porous structure formed at least on its surface to contact cells to inhibit growth of the cells in the contact area, a medical instrument including a medical instrument substrate and a film including a resin and having a porous structure formed at least on its surface, in which the surface of the medical instrument substrate is entirely or partially covered with the film, and a digestive system stent including a stent substrate and a film including a resin and having a porous structure formed by through-holes with an average pore size of 0.1 to 20 μm and a coefficient of variation in pore size of 30% or less, in which the stent substrate is covered with the film. According to the present invention, a material exhibiting cell growth inhibitory effects without using a physiologically active substance and suitable for forming a medical instrument, and a digestive system stent which secures a digestive system tubular cavity in the body and allows a digestive fluid and digestive enzymes contained therein to pass through, but blocks cancer cells, can be provided.

    摘要翻译： 至少在其表面形成有具有多孔结构的树脂的细胞生长抑制膜，细胞生长抑制方法，包括使包含树脂的膜的表面至少在其表面形成的多孔结构的表面与细胞接触 抑制接触区域中的细胞生长，包括医疗仪器基板的医疗器械和包括树脂的膜，并且至少在其表面上形成有多孔结构，其中医疗器械基板的表面完全或部分覆盖 以及包括支架基板和包含树脂的薄膜的消化系统支架，并且具有通过平均孔径为0.1〜20μm的通孔形成的多孔结构，孔径的变异系数为30％ 或更少，其中支架基底被膜覆盖。 根据本发明，不使用生理活性物质并且适于形成医疗器械的细胞生长抑制作用的材料，以及消化系统支架，其将消化系统管状空腔固定在体内并允许消化液和消化酶 可以提供包含在其中的通道，但可以阻止癌细胞。

    Process for producing micropillar structure
    7.
    发明授权
    Process for producing micropillar structure 有权
    微柱结构生产工艺

    公开(公告)号：US07799378B2

    公开(公告)日：2010-09-21

    申请号：US10536589

    申请日：2003-11-27

    申请人： Masaru Tanaka ,  Masatsugu Shimomura ,  Masafumi Takebayashi ,  Hiroshi Yabu

    发明人： Masaru Tanaka ,  Masatsugu Shimomura ,  Masafumi Takebayashi ,  Hiroshi Yabu

    IPC分类号： B05D5/00 ,  B05D7/24 ,  B05D3/10 ,  B05D3/12 ,  B29C41/12 ,  B29C41/36 ,  B29D28/00 ,  C12M3/00 ,  C08J9/00

    CPC分类号： B01D69/06 ,  B29C59/022 ,  B29C59/026 ,  B29C2059/023 ,  B29K2105/0073 ,  B29L2007/008 ,  B29L2031/608 ,  B29L2031/755 ,  B29L2031/756

    摘要： A solution having a polymer dissolved in a hydrophobic organic solvent is cast on a substrate, said organic solvent is evaporated in a moist atmosphere to condense moisture contained in an atmosphere prevailing on a surface of said cast solution into micro-droplets, said micro-droplets are dispersed on the surface of said cast solution or in said cast solution into a close-packed structure, said micro-droplets, condensed and dispersed on the surface of said cast solution or in said cast solution, are evaporated to obtain a porous honeycomb structure with said droplets used as casts, and said porous honeycomb structure is at least bisected by peeling in a thickness direction, thereby obtaining honeycomb structures wherein micro-pillars or anisotropic micro-pillars are regularly formed and arranged by said bisection on the peeled sections.

    摘要翻译： 将溶解在疏水性有机溶剂中的聚合物的溶液浇铸在基材上，将所述有机溶剂在潮湿气氛中蒸发以将包含在所述流延溶液表面上的气氛中的水分浓缩成微滴，所述微滴 分散在所述流延溶液的表面或所述流延溶液中形成紧密堆积的结构，所述微滴在所述流延溶液或所述流延溶液的表面上被冷凝并分散，得到多孔蜂窝结构体 其中所述小滴用作铸件，并且所述多孔蜂窝结构通过在厚度方向上的剥离至少被二等分，从而获得其中微柱或各向异性微柱规则地形成并且通​​过在剥离部分上的所述二等分布置的蜂窝结构。

    CELL CHIP
    9.
    发明申请
    CELL CHIP 审中-公开
    电池芯片

    公开(公告)号：US20100035766A1

    公开(公告)日：2010-02-11

    申请号：US12302705

    申请日：2007-05-30

    申请人： Masaru Tanaka ,  Shusaku Tsukiyama ,  Sadaaki Yamamoto ,  Masatsugu Shimomura ,  Hidekazu Yamazaki ,  Hideaki Naruse

    发明人： Masaru Tanaka ,  Shusaku Tsukiyama ,  Sadaaki Yamamoto ,  Masatsugu Shimomura ,  Hidekazu Yamazaki ,  Hideaki Naruse

    IPC分类号： C40B30/06 ,  C40B40/02

    CPC分类号： G01N33/5067 ,  C12N9/96 ,  C12Q1/02 ,  G01N33/54366

    摘要： Disclosed is a novel cell chip having a living cell retained on a substrate while keeping the functions of the cell. Specifically, disclosed is a cell chip which comprises a honeycomb-like porous material having through-pores therein and composed of a water-insoluble polymer and a human hepatocyte retained on the porous material. The cell chip, particularly one having a human hepatocyte retained on both surfaces of the honeycomb-like porous material, is advantageous, because it can keep the activity of a drug-metabolizing enzyme (particularly, a P450 activity) for a long period, can keep the number of the cells stably, and so on.

    摘要翻译： 公开了一种新颖的细胞芯片，其具有在保持细胞功能的同时保留在基板上的活细胞。 具体地，公开了一种细胞芯片，其包括其中具有通孔的蜂窝状多孔材料，其由保持在多孔材料上的水不溶性聚合物和人肝细胞组成。 特别是在蜂窝状多孔质体的两面保留有人肝细胞的细胞芯片是有利的，因为它可以长时间保持药物代谢酶（特别是P450活性）的活性，可以 保持细胞的数量稳定，等等。

    Anisotropic Conductive Film and a Method of Manufacturing the Same
    10.
    发明申请
    Anisotropic Conductive Film and a Method of Manufacturing the Same 审中-公开
    各向异性导电膜及其制造方法

    公开(公告)号：US20070212521A1

    公开(公告)日：2007-09-13

    申请号：US10593622

    申请日：2005-03-29

    申请人： Hisami Bessho ,  Hideyuki Sato ,  Akio Sato ,  Masatsugu Shimomura ,  Masaru Tanaka ,  Hiroshi Yabu

    发明人： Hisami Bessho ,  Hideyuki Sato ,  Akio Sato ,  Masatsugu Shimomura ,  Masaru Tanaka ,  Hiroshi Yabu

    IPC分类号： B32B3/10

    CPC分类号： H01R12/7076 ,  C09J7/22 ,  C09J7/26 ,  C09J2201/128 ,  C09J2201/602 ,  H01R13/2414 ,  H05K3/323 ,  H05K2201/0116 ,  H05K2201/09945 ,  H05K2201/10378 ,  Y10T428/24322

    摘要： To provide an anisotropic conductive film which can respond to increasing pitch reduction of connection targets while maintaining connection reliability, and can be manufactured at a lower cost than conventional, and to provide a method of manufacturing the same. The anisotropic conductive film is provided with a porous film consisting of polymer, having numerous holes penetrating in a film thickness direction, the holes being in a honeycomb arrangement and having inner wall surfaces which curve outwards, a conductive material that fills the holes in the porous film, and an adhesive layer coated on both surfaces of the porous film. The porous film is formed by leaving a supporting substrate on which cast is a polymer solution where a polymer is dissolved in a hydrophobic, volatile organic solvent, under high humidity conditions.

    摘要翻译： 为了提供能够对维持连接可靠性的连接目标的减小的增加作出响应的各向异性导电膜，并且可以以比传统的更低的成本制造并提供其制造方法。 各向异性导电膜设置有由聚合物组成的多孔膜，其具有沿膜厚度方向穿透的多个孔，该孔为蜂窝结构，并且具有向外弯曲的内壁表面，填充多孔的孔的导电材料 膜和涂覆在多孔膜的两个表面上的粘合剂层。 多孔膜通过在高湿度条件下留下支撑基底而形成，其上浇注聚合物溶液，其中聚合物溶解在疏水性挥发性有机溶剂中。