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    Spiral mixer nozzle and method for mixing two or more fluids and process for manufacturing isocyanates
    1.
    发明授权
    Spiral mixer nozzle and method for mixing two or more fluids and process for manufacturing isocyanates 有权
    螺旋混合器喷嘴和混合两种或多种流体的方法和用于制造异氰酸酯的方法

    公开(公告)号：US09498757B2

    公开(公告)日：2016-11-22

    申请号：US14468363

    申请日：2014-08-26

    申请人： Huntsman International LLC

    发明人： Neal Anthony Grob ,  James LaVerne Allbright

    IPC分类号： B01F5/02 ,  B01F3/08 ,  B01F15/02 ,  B01F5/04 ,  B01F5/00

    CPC分类号： B01F5/0281 ,  B01F3/08 ,  B01F5/0077 ,  B01F5/0403 ,  B01F5/046 ,  B01F15/0254 ,  Y10T137/87652

    摘要： An apparatus for mixing at least first and second fluid, comprising: (a) a first nozzle comprising a first flow duct defining a first flow chamber, and having a first nozzle tip having a first discharge opening; and (b) a second nozzle comprising a second flow duct defining a second flow chamber, and having a second nozzle tip having a second discharge opening; wherein said first flow duct and said second flow duct are spirally wrapped each over the other. The invention also provides a process for mixing fluids, especially adapted for the production of isocyanates, and that is notably carried out in the apparatus of the invention.

    摘要翻译： 一种用于混合至少第一和第二流体的装置，包括：（a）第一喷嘴，包括限定第一流动室的第一流动管道，并且具有第一喷嘴末端，所述第一喷嘴尖端具有第一排出口; 和（b）第二喷嘴，其包括限定第二流动室的第二流动管道，并且具有具有第二排放口的第二喷嘴尖端; 其中所述第一流动管道和所述第二流动管道螺旋地缠绕在另一个上。 本发明还提供了一种用于混合流体的方法，特别适用于生产异氰酸酯，并且在本发明的装置中显着地进行。

    Micro mixing and reaction device
    2.
    发明授权
    Micro mixing and reaction device 失效
    微混合反应装置

    公开(公告)号：US07434982B2

    公开(公告)日：2008-10-14

    申请号：US10854747

    申请日：2004-05-27

    申请人： Hideharu Nagasawa ,  Kazuhiro Mae

    发明人： Hideharu Nagasawa ,  Kazuhiro Mae

    IPC分类号： B01F5/00 ,  B01F15/06

    CPC分类号： B01F13/0062 ,  B01F5/0453 ,  B01F5/046 ,  B01F11/02 ,  B01F13/0006 ,  B01F13/0066 ,  B01F2215/0422 ,  B01F2215/0431 ,  B01J19/0093 ,  B01J2219/00788 ,  B01J2219/0086 ,  G03C1/49809

    摘要： There is provided a microdevice in which a plurality of fluids L1, L2 and L3 are caused to pass through respective fluid supply passages and flow together in one mixing reaction flow path, and the fluids are diffused in the normal direction of the contact interface thereof while being allowed to flow as a thin layer shaped laminar flow, by which mixing or reaction is carried out. The fluid supply passages are of a concentric multiple cylindrical construction to concentrically laminate the fluids L1, L2 and L3 joined together in the mixing reaction flow path, and the opening width near a joining point of the fluids is reduced to contract the flow.

    摘要翻译： 提供了一种微型装置，其中使多个流体L 1，L 2和L 3通过各个流体供应通道并在一个混合反应流动路径中一起流动，并且流体沿着接触的法线方向扩散 界面，同时被允许作为薄层形状的层流流动，由此进行混合或反应。 流体供给通道是同心多重圆柱形结构，以使混合反应流动路径中连接在一起的流体L 1，L 2和L 3同心地层压，并且减少流体接合点附近的开口宽度以收缩流动 。

    Reactor apparatus and mixing inlet and methods
    4.
    发明申请
    Reactor apparatus and mixing inlet and methods 审中-公开
    反应器设备和混合入口及方法

    公开(公告)号：US20040156763A1

    公开(公告)日：2004-08-12

    申请号：US10471466

    申请日：2004-04-07

    发明人： Mark D. Wood ,  Andrew J. Green

    IPC分类号： B01J010/00

    CPC分类号： F28F9/027 ,  B01F5/0413 ,  B01F5/0451 ,  B01F5/0453 ,  B01F5/046 ,  B01F5/0615 ,  B01F5/0618 ,  B01J19/0053 ,  B01J19/006 ,  B01J19/0066 ,  B01J19/0073 ,  B01J19/243 ,  B01J2219/00085 ,  B01J2219/00765 ,  F28D7/06 ,  F28D2021/0052 ,  F28F9/26 ,  F28F13/12 ,  F28F2280/02

    摘要： The invention relates to reactor apparatus (1) comprising an assembly of a plurality of separate conduits (2) disposed within a vessel (3) for heat exchange between the conduits (2) and a medium (not shown) in the vessel (3), the separate conduits (2) being connectible to define one or more flow paths through the reactor (1), the length of the or each flow path being variable by adjusting the number of conduits connected such that the residence tine of reactants flowing in the or each flow path can be varied, and a mixing inlet (100) for mixing fluids comprising a conduit (200) adapted to be inserted into a fluid flow device (300) and means (400) disposed about the outer surface (700) of the conduit (200) to create turbulence in fluid in the device (300), there being at least one aperture (600) in the conduit (200) for addition and an additive, the turbulence causing mixing of the additive into the fluid show. Such a mixing inlet (100) can be used with reactor apparatus as described above.

    摘要翻译： 本发明涉及一种反应器装置（1），其包括设置在容器（3）内的多个分离管道（2）的组件，用于管道（2）和容器（3）中的介质（未示出）之间的热交换， ，分离的管道（2）可连接以限定通过反应器（1）的一个或多个流动路径，所述每个流动路径的长度可通过调节所连接的管道的数量而变化，使得在 或每个流动路径可以变化，并且用于混合流体的混合入口（100）包括适于插入到流体流动装置（300）中的导管（200）和围绕外表面（700）设置的装置（400） 所述管道（200）在所述装置（300）中产生流体中的湍流，所述导管（200）中具有用于添加的至少一个孔（600）和添加剂，所述湍流引起所述添加剂混入流体显示。 这样的混合入口（100）可以与如上所述的反应器装置一起使用。

    Process and apparatus for producing inhalable medicaments
    5.
    发明授权
    Process and apparatus for producing inhalable medicaments 有权
    生产可吸入药物的方法和设备

    公开(公告)号：US06663848B2

    公开(公告)日：2003-12-16

    申请号：US10125044

    申请日：2002-04-18

    申请人： Joerg Schiewe ,  Bernd Zierenberg

    发明人： Joerg Schiewe ,  Bernd Zierenberg

    IPC分类号： A61K912

    CPC分类号： B01F13/0071 ,  A61K9/0073 ,  A61K9/0075 ,  A61K9/14 ,  A61K9/1688 ,  B01D9/0013 ,  B01D9/0036 ,  B01D9/0063 ,  B01F5/0453 ,  B01F5/046 ,  B01F13/0066 ,  B01F2005/0031 ,  B01F2215/0431 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/0086 ,  B01J2219/00873 ,  B01J2219/00889 ,  B01J2219/00984 ,  B01J2219/0245

    摘要： A method for crystallizing a substance, especially an inhalable medicament, comprising the following steps: (a) dissolving said substance in a solvent, to produce a solution of said substance, (b) producing a segmented stream which consists of alternating segments of said solution of the substance and of a transport medium, (c) introducing said segmented stream into the first end of a retention stretch, which retention stretch has a first end and a second end, so that said segmented stream passes from said first end to said second end of said retention stretch, and exits from the second end of the retention stretch, (d) cooling the retention stretch, to thereby bring about crystallization of the substance in the segments of solution, in the segmented stream, as said segmented stream passes through the retention stretch, and (e) separating the crystals of material from the segmented stream as it exits from the second end of the retention stretch. Also disclosed is an apparatus for carrying out the method.

    摘要翻译： 一种使物质特别是可吸入药物结晶的方法，包括以下步骤：（a）将所述物质溶解在溶剂中，以产生所述物质的溶液，（b）产生由所述溶液的交替段组成的分段流 的物质和运输介质，（c）将所述分段流引入保持拉伸的第一端，所述保持拉伸具有第一端和第二端，使得所述分段流从所述第一端到所述第二端 所述保留拉伸的端部并且从保持拉伸的第二端离开，（d）冷却保留拉伸，从而在分段流中导致溶液段中物质的结晶，因为所述分段流通过 保留拉伸，以及（e）从分段流中的晶体从保留拉伸的第二端离开时也分离。还公开了一种用于承载ou 方法。

    Cell suspension preparation apparatus and method
    7.
    发明授权
    Cell suspension preparation apparatus and method 失效
    细胞悬浮液制备装置及方法

    公开(公告)号：US5589394A

    公开(公告)日：1996-12-31

    申请号：US356412

    申请日：1994-12-15

    申请人： Young R. Kim ,  Kenneth E. Iles ,  Roderick W. Larue

    发明人： Young R. Kim ,  Kenneth E. Iles ,  Roderick W. Larue

    IPC分类号： B01F5/04 ,  G01N1/00 ,  G01N15/00 ,  G01N15/14 ,  G01N35/00 ,  G01N35/10 ,  H01N35/10

    CPC分类号： B01F5/0453 ,  B01F5/046 ,  G01N15/14 ,  G01N15/1404 ,  G01N35/0092 ,  G01N35/1004 ,  G01N35/109 ,  G01N1/14 ,  G01N2015/0076 ,  G01N2015/0084 ,  G01N2015/1413 ,  G01N2035/00356 ,  G01N2035/00524 ,  G01N2035/1032 ,  G01N35/10 ,  Y10T436/11 ,  Y10T436/119163 ,  Y10T436/25 ,  Y10T436/25625 ,  Y10T436/2575

    摘要： Embodiments described herein provide apparatuses and methods for preparing fluid. In one method, a heater thermally associated with a housing for receiving fluid is operated to apply thermal energy to the housing. A second predetermined volume of a second fluid is introduced to the housing. The second predetermined volume of the second fluid is moved with the housing for a first predetermined time period. The first predetermined volume of the first fluid is introduced to the housing. The first predetermined volume of first fluid and the second predetermined volume of second fluid are moved with the housing for a second predetermined time period. The first predetermined volume of first fluid and the second predetermined volume of second fluid are removed from the housing. Another embodiment provides an apparatus comprising a first housing for containing fluid. A second housing is operatively connected with the first housing. A prime mover is fixedly-attached to the second housing and is operatively connected with the first housing such that the first housing moves responsive to the prime mover and such that the second housing remains substantially stationary with respect to the prime mover. A fluid inlet is fluidly connected with the first housing for supplying fluid to the first housing. A fluid outlet is fluidly connected with the first housing for removing fluid from the first housing.

    摘要翻译： 本文所述的实施例提供了用于制备流体的装置和方法。 在一种方法中，与用于接收流体的壳体热相关联的加热器被操作以将热能施加到壳体。 第二流体的第二预定体积被引入壳体。 第二流体的第二预定体积与壳体一起移动第一预定时间段。 将第一流体的第一预定体积引入壳体。 第一预定体积的第一流体和第二预定体积的第二流体与壳体一起移动第二预定时间段。 将第一预定体积的第一流体和第二预定体积的第二流体从壳体移除。 另一个实施例提供一种包括用于容纳流体的第一壳体的装置。 第二壳体与第一壳体可操作地连接。 原动机固定地附接到第二壳体并且与第一壳体可操作地连接，使得第一壳体响应于原动机而移动，并且使得第二壳体相对于原动机基本上保持静止。 流体入口与第一壳体流体连接以将流体供应到第一壳体。 流体出口与第一壳体流体连接以从第一壳体移除流体。

    Spiral mixer nozzle and method for mixing two or more fluids and process for manufacturing isocyanates
    8.
    发明授权
    Spiral mixer nozzle and method for mixing two or more fluids and process for manufacturing isocyanates 有权
    螺旋混合器喷嘴和用于混合两种或多种流体的方法和用于制造异氰酸酯的方法

    公开(公告)号：US08844574B2

    公开(公告)日：2014-09-30

    申请号：US11910945

    申请日：2006-03-06

    申请人： Neal Anthony Grob ,  James LaVerne Allbright

    发明人： Neal Anthony Grob ,  James LaVerne Allbright

    IPC分类号： B01F5/04 ,  C07C263/00 ,  B01F5/00

    CPC分类号： B01F5/0281 ,  B01F3/08 ,  B01F5/0077 ,  B01F5/0403 ,  B01F5/046 ,  B01F15/0254 ,  Y10T137/87652

    摘要： An apparatus for mixing at least first and second fluid, comprising: (a) a first nozzle comprising a first flow duct defining a first flow chamber, and having a first nozzle tip having a first discharge opening; and (b) a second nozzle comprising a second flow duct defining a second flow chamber, and having a second nozzle tip having a second discharge opening; wherein said first flow duct and said second flow duct are spirally wrapped each over the other. The invention also provides a process for mixing fluids, especially adapted for the production of isocyanates, and that is notably carried out in the apparatus of the invention.

    摘要翻译： 一种用于混合至少第一和第二流体的装置，包括：（a）第一喷嘴，包括限定第一流动室的第一流动管道，并且具有第一喷嘴末端，所述第一喷嘴尖端具有第一排出口; 和（b）第二喷嘴，其包括限定第二流动室的第二流动管道，并且具有具有第二排放口的第二喷嘴尖端; 其中所述第一流动管道和所述第二流动管道螺旋地缠绕在另一个上。 本发明还提供了一种用于混合流体的方法，特别适用于生产异氰酸酯，并且在本发明的装置中显着地进行。

    Fluid mixing apparatus and fluid mixing method
    9.
    发明授权
    Fluid mixing apparatus and fluid mixing method 有权
    流体混合装置和流体混合方法

    公开(公告)号：US07780929B2

    公开(公告)日：2010-08-24

    申请号：US11727816

    申请日：2007-03-28

    申请人： Takayuki Fujiwara ,  Kazuo Okutsu

    发明人： Takayuki Fujiwara ,  Kazuo Okutsu

    IPC分类号： B01J19/00 ,  B01J8/02 ,  B01F5/06

    CPC分类号： B01F13/0067 ,  B01F5/0453 ,  B01F5/046 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00819 ,  B01J2219/00862 ,  B01J2219/00889 ,  B01J2219/00891 ,  B33Y80/00

    摘要： The present invention provides a fluid mixing apparatus having a numbering-up mechanism that distributes plural kinds of fluids and concurrently performs multiple mixing or reactions, comprising: a rectifying section having a plurality of annular channels that rectify the plural kinds of fluids into respective concentric annular flows; a distribution section having a plurality of distribution channels that distribute the plural kinds of fluids rectified by the rectifying section into a plurality of flows; a converging section having a plurality of converging channels that converge different kinds of fluids among the plural kinds of fluids distributed by the distribution section; and a mixing/reaction section having a plurality of mixing/reaction channels that cause mixing or reaction of the plural kinds of fluids converged by the converging section, wherein a plurality of pressure loss increasing devices are provided in the distribution channels.

    摘要翻译： 本发明提供一种具有分配多种流体并同时进行多次混合或反应的编号机构的流体混合装置，包括：整流部分，具有多个环形通道，将多种流体整流成各自的同心环形 流动 分配部分，具有多个分配通道，将由整流部分整流的多种流体分配成多个流; 会聚部分，具有会聚不同种类的流体的多个会聚通道，所述多个会聚通道在由所述分配部分布的多种流体中聚集; 以及具有多个混合/反应通道的混合/反应部分，其引起由会聚部分会聚的多种流体的混合或反应，其中在分配通道中设置多个压力增加装置。