-
公开(公告)号：US20240117388A1
公开(公告)日：2024-04-11
申请号：US18273261
申请日：2022-01-20
申请人： BAYMEDICA, INC.
发明人： James T. KEALEY , James P. CRAIG , Jianping SUN , Charles K. MARLOWE , Colin W. JOHNSON , Philip J. BARR
CPC分类号： C12P7/22 , C12N9/1085 , C12N9/13 , C12N9/88 , C12N9/93 , C12N15/52 , C12P7/42 , C12Y205/01102 , C12Y208/03001 , C12Y208/03008 , C12Y404/01026 , C12Y602/01012
摘要： Enzymes and recombinant host cells for the biosynthesis of clinically important prenylated polyketides of the cannabinoid family are provided. Using readily available starting materials, heterologous enzymes (e.g., bacterial CoA-transferases and CoA-ligases) are used to direct cannabinoid biosynthesis in host cells such as recombinant yeast cells.
-
公开(公告)号：US20170159080A1
公开(公告)日：2017-06-08
申请号：US15441109
申请日：2017-02-23
CPC分类号： C12P7/26 , A01H6/28 , A61K31/352 , C12M21/18 , C12M41/30 , C12M41/48 , C12N9/0004 , C12N9/1029 , C12P7/04 , C12P7/22 , C12P7/42 , C12P7/62 , C12P17/06 , C12Y121/03007 , C12Y121/03008 , C12Y203/01206 , C12Y205/01102 , Y02A50/473
摘要： The present invention provides methods for producing cannabinoids and cannabinoid analogs as well as a system for producing these compounds. The inventive method is directed to contacting a compound according to Formula I or Formula II with a cannabinoid synthase. Also described is a system for producing cannabinoids and cannabinoid analogs by contacting a THCA synthase with a cannabinoid precursor and modifying at least one property of the reaction mixture to influence the quantity formed of a first cannabinoid relative to the quantity formed of a second cannabinoid.
-
公开(公告)号：US20230340506A1
公开(公告)日：2023-10-26
申请号：US18054917
申请日：2022-11-14
发明人： Jay D. KEASLING , Leo D′ESPAUX , Jeff WONG , Xiaozhou LUO , Michael REITER , Charles DENBY , Anna LECHNER
CPC分类号： C12N15/81 , C07C63/04 , C12N9/1085 , C12N15/70 , C12N15/8243 , C12P7/42 , C12N15/52 , C12Y101/01088 , C12Y203/01086 , C12Y203/01206 , C12Y203/0301 , C12Y205/01102 , C12Y207/01036 , C12Y207/04002 , C12Y401/01033 , C12Y503/03002 , C12Y602/01003 , C12Y604/01002
摘要： The present disclosure provides genetically modified host cells that produce a cannabinoid, a cannabinoid derivative, a cannabinoid precursor, or a cannabinoid precursor derivative. The present disclosure provides methods of synthesizing a cannabinoid, a cannabinoid derivative, a cannabinoid precursor, or a cannabinoid precursor derivative.
-
4.发明申请公开(公告)号：US20150361469A1
公开(公告)日：2015-12-17
申请号：US14836339
申请日：2015-08-26
发明人： ROBERT WINNICKI , Marc Donsky
CPC分类号： C12P7/22 , A01H6/28 , A61K31/352 , C12M21/18 , C12M41/30 , C12M41/48 , C12N9/0004 , C12N9/1029 , C12P7/04 , C12P7/26 , C12P7/42 , C12P7/62 , C12P17/06 , C12Y121/03007 , C12Y121/03008 , C12Y203/01206 , C12Y205/01102
摘要： The present invention provides methods for producing cannabinoids and cannabinoid analogs as well as a system for producing these compounds. The inventive method is directed to contacting a compound according to Formula I or Formula II with a cannabinoid synthase. Also described is a system for producing cannabinoids and cannabinoid analogs by contacting a THCA synthase with a cannabinoid precursor and modifying at least one property of the reaction mixture to influence the quantity formed of a first cannabinoid relative to the quantity formed of a second cannabinoid.
摘要翻译： 本发明提供了制造大麻素类和大麻素类似物的方法以及这些化合物的制造方法。 本发明的方法是将式I或式II化合物与大麻素合酶接触。 还描述了通过使THCA合酶与大麻素前体接触并修饰反应混合物的至少一种性质来影响相对于第二种大麻素形成的量形成的第一大麻素的量的生产大麻素和大麻素类似物的系统。
-
公开(公告)号：US09861609B2
公开(公告)日：2018-01-09
申请号：US15242189
申请日：2016-08-19
发明人： Robert Winnicki , Marc Donsky , Mingyang Sun , Richard Peet
IPC分类号： C12N1/20 , C12N1/16 , A61K31/352 , C12M1/40 , C12M1/34 , C12P17/06 , C12P7/42 , C12M1/36 , A61K38/00
CPC分类号： C12P7/22 , A01H6/28 , A61K31/352 , C12M21/18 , C12M41/30 , C12M41/48 , C12N9/0004 , C12N9/1029 , C12P7/04 , C12P7/26 , C12P7/42 , C12P7/62 , C12P17/06 , C12Y121/03007 , C12Y121/03008 , C12Y203/01206 , C12Y205/01102
摘要： The present invention provides methods for producing cannabinoids and cannabinoid analogs as well as a system for producing these compounds. The inventive method is directed to contacting a compound according to Formula I or Formula II with a cannabinoid synthase. Also described is a system for producing cannabinoids and cannabinoid analogs by contacting a THCA synthase with a cannabinoid precursor and modifying at least one property of the reaction mixture to influence the quantity formed of a first cannabinoid relative to the quantity formed of a second cannabinoid.
-
6.发明授权公开(公告)号：US09526715B1
公开(公告)日：2016-12-27
申请号：US15171517
申请日：2016-06-02
发明人： Robert Winnicki , Marc Donsky
CPC分类号： C12P7/22 , A01H6/28 , A61K31/352 , C12M21/18 , C12M41/30 , C12M41/48 , C12N9/0004 , C12N9/1029 , C12P7/04 , C12P7/26 , C12P7/42 , C12P7/62 , C12P17/06 , C12Y121/03007 , C12Y121/03008 , C12Y203/01206 , C12Y205/01102
摘要： The present invention provides methods for producing cannabinoids and cannabinoid analogs as well as a system for producing these compounds. The inventive method is directed to contacting a compound according to Formula I or Formula II with a cannabinoid synthase. Also described is a system for producing cannabinoids and cannabinoid analogs by contacting a THCA synthase with a cannabinoid precursor and modifying at least one property of the reaction mixture to influence the quantity formed of a first cannabinoid relative to the quantity formed of a second cannabinoid.
摘要翻译： 还描述了通过使THCA合酶与大麻素前体接触并修饰反应混合物的至少一种性质来影响相对于第二种大麻素形成的量形成的第一大麻素的量的生产大麻素和大麻类似物的系统。
-
公开(公告)号：US20160355854A1
公开(公告)日：2016-12-08
申请号：US15242189
申请日：2016-08-19
发明人： Robert WINNICKI , Marc DONSKY , Mingyang SUN , Richard PEET
CPC分类号： C12P7/22 , A01H6/28 , A61K31/352 , C12M21/18 , C12M41/30 , C12M41/48 , C12N9/0004 , C12N9/1029 , C12P7/04 , C12P7/26 , C12P7/42 , C12P7/62 , C12P17/06 , C12Y121/03007 , C12Y121/03008 , C12Y203/01206 , C12Y205/01102
摘要： The present invention provides methods for producing cannabinoids and cannabinoid analogs as well as a system for producing these compounds. The inventive method is directed to contacting a compound according to Formula I or Formula II with a cannabinoid synthase. Also described is a system for producing cannabinoids and cannabinoid analogs by contacting a THCA synthase with a cannabinoid precursor and modifying at least one property of the reaction mixture to influence the quantity formed of a first cannabinoid relative to the quantity formed of a second cannabinoid.
-
公开(公告)号：US10081818B2
公开(公告)日：2018-09-25
申请号：US15430122
申请日：2017-02-10
CPC分类号： C12P7/26 , A01H6/28 , A61K31/352 , C12M21/18 , C12M41/30 , C12M41/48 , C12N9/0004 , C12N9/1029 , C12P7/04 , C12P7/22 , C12P7/42 , C12P7/62 , C12P17/06 , C12Y121/03007 , C12Y121/03008 , C12Y203/01206 , C12Y205/01102 , Y02A50/473
摘要： The present invention provides methods for producing cannabinoids and cannabinoid analogs as well as a system for producing these compounds. The inventive method is directed to contacting a compound according to Formula I or Formula II with a cannabinoid synthase. Also described is a system for producing cannabinoids and cannabinoid analogs by contacting a THCA synthase with a cannabinoid precursor and modifying at least one property of the reaction mixture to influence the quantity formed of a first cannabinoid relative to the quantity formed of a second cannabinoid.
-
公开(公告)号：US20170247650A1
公开(公告)日：2017-08-31
申请号：US15594348
申请日：2017-05-12
CPC分类号： C12P7/26 , A01H6/28 , A61K31/352 , C12M21/18 , C12M41/30 , C12M41/48 , C12N9/0004 , C12N9/1029 , C12P7/04 , C12P7/22 , C12P7/42 , C12P7/62 , C12P17/06 , C12Y121/03007 , C12Y121/03008 , C12Y203/01206 , C12Y205/01102 , Y02A50/473
摘要： The present invention provides methods for producing cannabinoids and cannabinoid analogs as well as a system for producing these compounds. The inventive method is directed to contacting a compound according to Formula I or Formula II with a cannabinoid synthase. Also described is a system for producing cannabinoids and cannabinoid analogs by contacting a THCA synthase with a cannabinoid precursor and modifying at least one property of the reaction mixture to influence the quantity formed of a first cannabinoid relative to the quantity formed of a second cannabinoid.
-
公开(公告)号：US20170152530A1
公开(公告)日：2017-06-01
申请号：US15430122
申请日：2017-02-10
CPC分类号： C12P7/22 , A01H6/28 , A61K31/352 , C12M21/18 , C12M41/30 , C12M41/48 , C12N9/0004 , C12N9/1029 , C12P7/04 , C12P7/26 , C12P7/42 , C12P7/62 , C12P17/06 , C12Y121/03007 , C12Y121/03008 , C12Y203/01206 , C12Y205/01102
摘要： The present invention provides methods for producing cannabinoids and cannabinoid analogs as well as a system for producing these compounds. The inventive method is directed to contacting a compound according to Formula I or Formula II with a cannabinoid synthase. Also described is a system for producing cannabinoids and cannabinoid analogs by contacting a THCA synthase with a cannabinoid precursor and modifying at least one property of the reaction mixture to influence the quantity formed of a first cannabinoid relative to the quantity formed of a second cannabinoid.
-
-
-
-
-
-
-
-
-
搜索结果
12 条记录 (耗时 0.015 秒)
