公开(公告)号：US20040235187A1

公开(公告)日：2004-11-25

申请号：US10849293

申请日：2004-05-20

申请人： University of Maryland, Baltimore County

发明人： William R. LaCourse ,  Ronita L. Marple

IPC分类号： G01N030/02

CPC分类号： G01N30/88 ,  G01N30/78 ,  G01N2030/027 ,  G01N2030/085 ,  Y10T436/25375

摘要： The present application relates to apparatus for sampling and analysis of analytes in a liquid sample. A liquid sample is pre-concentrated using a chromatographic column prior to analysis via a two stage analysis apparatus. A high-performance liquid chromatography system with ultra violet detection may be used in conjunction with electrochemical detection for the analysis of environmental contaminants, including explosive residues. The present invention also provides for on-site analysis of such contaminants. The present invention also provides for methods of analyzing the components of a liquid sample, including methods for on-site analysis.

摘要翻译： 本申请涉及用于对液体样品中的分析物进行取样和分析的装置。 使用色谱柱预先浓缩液体样品，然后通过两级分析仪分析。 具有紫外线检测的高效液相色谱系统可与电化学检测结合使用，用于分析环境污染物，包括爆炸性残留物。 本发明还提供了这种污染物的现场分析。 本发明还提供了分析液体样品的组分的方法，包括用于现场分析的方法。

公开(公告)号：US20040182134A1

公开(公告)日：2004-09-23

申请号：US10390345

申请日：2003-03-17

发明人： Stephen Staphanos ,  Po-Liang Chien

IPC分类号： G01N030/02

CPC分类号： G01N30/468 ,  G01N30/40 ,  G01N30/66 ,  G01N33/225 ,  G01N2030/201 ,  G01N2030/202

摘要： A gas chromatograph is provided for measuring energy content of a sample. The gas chromatograph includes a sample handling system enclosure and an analyzer enclosure. The sample handling system enclosure has a sample inlet port to receive a sample from a sample probe. The analyzer enclosure contains a first sample loop having a first volume, a second sample loop having a second volume, and a third sample loop having a third volume. Each of the first, second and third sample loops are operably coupled to the sample inlet port. First, second and third analysis columns are disposed within the analyzer enclosure and operably coupled to first, second and third sample loops, respectively. A thermal conductivity detector is disposed in the analyzer enclosure and includes a first portion operably coupled to the first column, and a second portion operably coupled to the second and third columns. The thermal conductivity detector provides signals indicative of thermal conductivity of each portion.

摘要翻译： 提供了用于测量样品的能量含量的气相色谱仪。 气相色谱仪包括样品处理系统外壳和分析仪外壳。 样品处理系统外壳具有样品入口端口，用于从样品探针接收样品。 分析仪外壳包含具有第一体积的第一样品环，具有第二体积的第二样品环和具有第三体积的第三样品环。 第一，第二和第三样品环中的每一个可操作地耦合到样品入口。 第一，第二和第三分析柱分别设置在分析器外壳内，并分别可操作地耦合到第一，第二和第三样品环。 导热性检测器设置在分析器外壳中，并且包括可操作地耦合到第一列的第一部分和可操作地连接到第二和第三列的第二部分。 热导率检测器提供指示每个部分的热导率的信号。

公开(公告)号：US20040035183A1

公开(公告)日：2004-02-26

申请号：US10438517

申请日：2003-05-14

申请人： The State of Oregon acting and through the State Board of Higher Education on behalf of Portl

发明人： Robert J. O'Brien ,  Thomas R. Smith

IPC分类号： G01N030/78 ,  G01N030/60 ,  G01N030/02 ,  G01N021/49 ,  G01D011/24

CPC分类号： G01N30/22 ,  G01N1/2202 ,  G01N1/24 ,  G01N1/40 ,  G01N30/08 ,  G01N30/8606 ,  G01N30/8641 ,  G01N2001/2223 ,  G01N2001/2238 ,  G01N2001/2282 ,  G01N2001/4027 ,  G01N2015/0046 ,  G01N2015/0092 ,  G01N2030/025 ,  G01N2030/207 ,  G01N2030/328 ,  G01N2030/625 ,  G01N2030/626 ,  G01N30/06 ,  G01N30/32

摘要： Methods and systems for analyzing samples, such as gas samples, are described. One method comprises providing a gas sample, increasing pressure applied to the gas sample to compress the sample to a smaller volume and provide a pneumatically focused gas sample, and analyzing the pneumatically focused gas sample using any of a variety of analytical techniques. Also disclosed are systems for gas analysis, including systems for analysis of pneumatically focused, and thereby concentrated, gas samples and for analysis of particulate matter in gas samples. Analytical systems constructed within personal computer cases also are disclosed.

摘要翻译： 描述了用于分析样品（如气体样品）的方法和系统。 一种方法包括提供气体样品，增加施加到气体样品的压力以将样品压缩到更小的体积并提供气动聚焦的气体样品，以及使用各种分析技术中的任何一种分析气动聚焦的气体样品。 还公开了用于气体分析的系统，包括用于气动聚焦的分析系统，从而分析气体样品，从而分析气体样品中的颗粒物质。 在个人计算机机箱内构建的分析系统也被公开。

公开(公告)号：US20030217923A1

公开(公告)日：2003-11-27

申请号：US10153854

申请日：2002-05-24

发明人： D. Jed Harrison ,  Abebaw Belay Jemere

IPC分类号： G01N027/26 ,  C12M001/34 ,  B01D015/08 ,  G01N030/02

CPC分类号： G01N30/56 ,  B01L2200/0678 ,  B01L2300/041 ,  B01L2400/0415 ,  G01N30/6095 ,  G01N2030/285 ,  G01N2030/565

摘要： The present invention provides an on-chip packed reactor bed design that allows for an effective exchange of packing materials such as beads at a miniaturized level. The present invention extends the function of microfluidic analysis systems to new applications including on-chip solid phase extraction (SPE) and on-chip capillary electrochromatography (CEC). The design can be further extended to include integrated packed bed immuno- or enzyme reactors.

公开(公告)号：US20030108448A1

公开(公告)日：2003-06-12

申请号：US10154409

申请日：2002-05-23

发明人： Richard Douglas Sacks ,  Tincuta Maria Veriotti ,  Megan Ellen McGuigan ,  Joshua Jonathan Mark Whiting

IPC分类号： G01N030/02

CPC分类号： G01N30/461 ,  G01N30/32 ,  G01N2030/025 ,  G01N2030/324 ,  G01N2030/623 ,  G06F17/3089 ,  Y10T436/24

摘要： A gas chromatography system having a computer-controlled venting valve system that delivers pressurized pulses to a column junction point of two series-coupled columns having different stationary-phase chemistries and a method of using the same. Each pressurized pulse causes a differential change in the carrier gas velocities in the two columns, which lasts for the duration of the pressurized pulse. Whereby, the pressurized pulse selectively increases the separation of a component pair that exhibits separation at the exit of the first column, but otherwise co-elutes from the column ensemble.

摘要翻译： 一种具有计算机控制排气阀系统的气相色谱系统，其将加压脉冲输送到具有不同固定相化学物质的两个串联偶合柱的柱结点，以及使用该脉冲的方法。 每个加压脉冲导致两列中的载气速度的差异变化，其持续加压脉冲的持续时间。 由此，加压脉冲选择性地增加在第一列的出口处表现出分离的组分对的分离，但是另外从柱集合中共洗脱。

公开(公告)号：US20030100124A1

公开(公告)日：2003-05-29

申请号：US10070544

申请日：2002-04-16

发明人： Jan Beens

IPC分类号： G01N030/02

CPC分类号： G01N30/465 ,  G01N30/463 ,  G01N2030/025 ,  G01N2030/122 ,  G01N2030/3023 ,  G01N2030/623 ,  Y10T436/204998 ,  Y10T436/25875

摘要： This invention relates to a modulator for use in gas chromatographic analysis, adopted for alternatively trapping and releasing fractions of solutes in a length of a capillary column within a chromatographic oven, characterized in that it comprises at least one nozzle placed to spray at least one jet in at least one corresponding place along said capillary column length, said nozzle(s) being connected each to a source of liquid CO2 via a related valve, and means for alternatively opening said valve(s) for a predetermined time, to cause a jet of liquid CO2 to impinge for said predetermined time on said column place and to leave the oven atmosphere to heat said column place after said predetermined time. The modulator can be used in a conventional GC system or in a two dimensional GC system, for modulating the analytes fed to the second capillary column.

摘要翻译： 本发明涉及一种用于气相色谱分析的调节剂，其用于交替地捕集和释放色谱烘箱内毛细管柱长度的溶质馏分，其特征在于，其包括至少一个喷嘴，其被喷射至少喷射至少一个喷嘴 在沿着所述毛细管柱长度的至少一个对应的位置中，所述喷嘴通过相关的阀连接到每个液体CO 2源，以及用于交替地打开所述阀一段预定时间的装置，以引起喷射 的液体CO 2在所述柱位置上冲击所述预定时间，并且在所述预定时间之后离开烘箱气氛以加热所述列位置。 调节剂可用于常规GC系统或二维GC系统中，用于调节进料到第二毛细管柱的分析物。

公开(公告)号：US20020192832A1

公开(公告)日：2002-12-19

申请号：US10190854

申请日：2002-07-08

申请人： Alltech Associates, Inc.

发明人： James M. Anderson JR. ,  Raaidah Saari-Hordhaus ,  Bart C. Benedict ,  Carl Sims ,  Yuri Gurner ,  Hung Anthony Pham

IPC分类号： G01N030/02

CPC分类号： G01N30/96 ,  G01N30/34 ,  G01N2030/965

摘要： Methods and devices for continuous electrochemically suppressed ion chromatography are disclosed. In preferred aspect of the invention, a chromatography effluent comprising analyte ions and electrolyte is split into a first chromatography effluent flow stream and a second chromatography effluent flow stream. Electrolysis ions selected from the group consisting of hydronium ions and hydroxide ions are generated by the electrolysis of water. Electrolysis ions of the same charge as the electrolyte and the second chromatography effluent stream are flowed through a stationary phase thereby suppressing the electrolyte in the second chromatography effluent flow stream. The analyte ions are subsequently detected in the suppressed second chromatography effluent flow stream.

摘要翻译： 公开了用于连续电化学抑制离子色谱法的方法和装置。 在本发明的优选方面，包含分析物离子和电解质的色谱流出物被分成第一层析流出物流和第二层析流出物流。 通过水的电解产生选自水合氢离子和氢氧根离子的电解离子。 与电解质和第二层析流出物流相同的电解离子流过固定相，从而抑制第二层析流出物流中的电解质。 随后在抑制的第二色谱流出物流中检测分析物离子。

公开(公告)号：US20020177233A1

公开(公告)日：2002-11-28

申请号：US10177080

申请日：2002-06-21

申请人： Dionex Corporation

发明人： Yan Liu ,  Hamish Small ,  Nebojsa Avdalovic

IPC分类号： G01N030/02

CPC分类号： G01N30/96 ,  C25B1/16 ,  C25B1/22 ,  G01N30/02 ,  G01N30/34 ,  G01N2030/965 ,  Y10T436/25 ,  B01D15/36 ,  B01D15/426

摘要： Method and apparatus for generating an acid or base, e.g. for chromatographic analysis of anions. For generating a base the method includes the steps of providing a cation source in a cation source reservoir, flowing an aqueous liquid stream through a base generation chamber separated from the cation source reservoir by a barrier (e.g. a charged membrane) substantially preventing liquid flow while providing a cation transport bridge, applying an electric potential between an anode cation source reservoir and a cathode in the base generation chamber to electrolytically generate hydroxide ions therein and to cause cations in the cation source reservoir to electromigrate and to be transported across the barrier toward the cathode to combine with the transported cations to form cation hydroxide, and removing the cation hydroxide in an aqueous liquid stream as an effluent from the first base generation chamber. Suitable cation sources include a salt solution, a cation hydroxide solution or cation exchange resin.

摘要翻译： 用于产生酸或碱的方法和设备，例如， 用于阴离子的色谱分析。 为了产生碱，该方法包括以下步骤：在阳离子源储存器中提供阳离子源，使水性液体流通过基本上防止液体流动的屏障（例如带电膜）与阳离子源储存器分离的碱性产生室流动， 提供阳离子输送桥，在基底产生室中的阳极阳离子源储存器和阴极之间施加电位以在其中电解产生氢氧根离子，并使阳离子源储存器中的阳离子电迁移并穿过屏障向着 阴极与所运送的阳离子结合以形成阳离子氢氧化物，并且以水溶液流中的阳离子氢氧化物作为来自第一碱基产生室的流出物除去。 合适的阳离子源包括盐溶液，阳离子氢氧化物溶液或阳离子交换树脂。

公开(公告)号：US20020160521A1

公开(公告)日：2002-10-31

申请号：US09893311

申请日：2001-06-27

发明人： Can Ozbal ,  Ian W. Hunter ,  John Linton

IPC分类号： G01N030/02

CPC分类号： G01N30/466 ,  B01F5/0085 ,  B01F13/0059 ,  B01J19/0046 ,  B01J2219/0036 ,  B01J2219/00387 ,  B01J2219/00414 ,  B01J2219/00418 ,  B01J2219/00479 ,  B01J2219/00495 ,  B01J2219/00515 ,  B01J2219/00518 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/00657 ,  B01J2219/00659 ,  B01J2219/00689 ,  B01J2219/00702 ,  B01J2219/0072 ,  B01L3/0262 ,  B01L3/0268 ,  B01L3/505 ,  B01L3/5085 ,  B01L2300/0812 ,  B01L2300/0845 ,  C40B60/14 ,  G01N30/24 ,  G01N30/7233 ,  G01N30/7266 ,  G01N30/84 ,  G01N35/00009 ,  G01N35/1095 ,  G01N2030/628 ,  G01N2030/8417 ,  G01N2035/1037 ,  G01N2035/1046 ,  Y10T436/115831 ,  G01N30/18

摘要： A system and method high throughput sample preparation and analysis using column chromatography. Each port in a plurality of ports has a port input that interfaces with a first fluid source and a port output. A fluidic circuit is coupled to each port output and to a second fluid source, the fluidic circuit for controlling fluid flow from the plurality of ports and the second fluid source. The fluidic circuit is also coupled to a plurality of chromatography columns. An interface to an analyzer receives output from at least one of the plurality of chromatography columns. The plurality of chromatography columns is moved relative to the analyzer via a translation stage, such that sample output from one of the plurality of chromatography columns can be selectively presented to the analyzer.

摘要翻译： 一种使用柱色谱法的高通量样品制备和分析的系统和方法。 多个端口中的每个端口具有与第一流体源和端口输出接口的端口输入。 流体回路耦合到每个端口输出端和第二流体源，流体回路用于控制来自多个端口和第二流体源的流体流。 流体回路还耦合到多个色谱柱。 分析仪的界面接收至少一个色谱柱的输出。 多个色谱柱经由平移台相对于分析器移动，使得从多个色谱柱中的一个色谱柱输出的样品可以选择性地呈现给分析器。

公开(公告)号：US20020146350A1

公开(公告)日：2002-10-10

申请号：US09888354

申请日：2001-06-22

发明人： Jiunn-Guang Lo ,  Shun-Hsiang Ke

IPC分类号： G01N030/02

CPC分类号： G01N30/02 ,  G01N2030/085 ,  Y10T436/24

摘要： A real time monitoring system for automatically monitoring a gaseous pollution sample in environment. The system includes a sample preprocess apparatus (SPA) for immediately processing the gaseous pollution sample at room temperature, wherein the gaseous pollution sample includes a polar and a non-polar compounds, a sample separation apparatus for separating the gaseous pollution sample, a sample analysis apparatus for analyzing a target compound of the gaseous pollution sample, and a data processing device for automatically processing an analyzed data of the target compound to achieve the real time monitoring system.

摘要翻译： 用于自动监测环境中的气体污染物的实时监测系统。 该系统包括用于在室温下立即处理气体污染样品的样品预处理装置（SPA），其中气体污染样品包括极性和非极性化合物，用于分离气体污染样品的样品分离装置，样品分析 用于分析气体污染样品的目标化合物的装置，以及用于自动处理目标化合物的分析数据以实现实时监测系统的数据处理装置。