-
Patent Agency Ranking21.发明申请ACETYLENIC ARYL SULFONAMIDE AND PHOSPHINIC ACID AMIDE HYDROXAMIC ACID TACE INHIBITORS 审中-公开乙酰氨基磺酰胺和磷酸酰胺羟基酸酸缓蚀剂
公开(公告)号：WO0044710A3
公开(公告)日：2000-12-21
申请号：PCT/US0002076
申请日：2000-01-27
Applicant: AMERICAN CYANAMID CO
Inventor： LEVIN JEREMY IAN , CHEN JAMES MING
IPC: C07D295/08 , A61K31/18 , A61K31/351 , A61K31/40 , A61K31/4409 , A61K31/495 , A61P1/00 , A61P1/02 , A61P1/04 , A61P1/16 , A61P5/50 , A61P7/02 , A61P9/00 , A61P9/04 , A61P9/08 , A61P9/10 , A61P13/12 , A61P17/02 , A61P17/16 , A61P19/00 , A61P19/02 , A61P19/08 , A61P25/04 , A61P25/28 , A61P27/02 , A61P27/10 , A61P29/00 , A61P31/18 , A61P35/04 , A61P37/06 , A61P43/00 , C07C303/40 , C07C309/42 , C07C309/87 , C07C311/00 , C07C311/29 , C07D213/68 , C07D295/12 , C07D309/12 , C07F9/36
CPC classification number: C07C309/42 , C07C311/29 , C07C2601/04 , C07F9/36
Abstract: Hydroxamic acids having formula (B) wherein the variables are as defined herein, are useful in treating disease conditions mediated by TNF- alpha such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.
Abstract translation: 具有式（B）的异羟肟酸（其中变量如本文所定义）可用于治疗由TNF-α介导的疾病状态，例如类风湿性关节炎，骨关节炎，败血症，AIDS，溃疡性结肠炎，多发性硬化症，克罗恩氏病和退行性软骨损失。
-
22.发明申请ACETYLENIC ORTHO-SULFONAMIDO AND PHOSPHINIC ACID AMIDO BICYCLIC HETEROARYL HYDROXAMIC ACIDS AS TACE INHIBITORS 审中-公开乙酰氨基磺酰胺和磷酸二氨基双酚A羟基酸作为抑制剂
公开(公告)号：WO00044749A1
公开(公告)日：2000-08-03
申请号：PCT/US2000/002144
申请日：2000-01-27
IPC: C07D471/00 , A61K31/00 , A61K31/437 , A61K31/4706 , A61P1/00 , A61P3/08 , A61P7/00 , A61P19/02 , A61P25/28 , A61P29/00 , A61P31/04 , A61P31/18 , A61P37/00 , A61P37/06 , A61P43/00 , C07C309/42 , C07C309/87 , C07D215/54 , C07D471/04 , C07D498/00 , C07D498/04 , C07D513/00 , C07D513/04 , C07F9/00 , A61K31/47 , C07F9/53
CPC classification number: C07D471/04 , C07C309/42 , C07C309/87 , C07D215/54 , C07D513/04
Abstract: Compounds of formulas (a), (b), (c), or (d) are provided wherein P and Q are (e) or (f), provided that when P is (e), Q is (f), and vice versa; which are useful in disease conditions mediated by TNF- alpha , such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.
Abstract translation: 提供式（a），（b），（c）或（d）的化合物，其中P和Q为（e）或（f），条件是当P为（e）时，Q为（f） 反之亦然; 其可用于由TNF-α介导的疾病状况，例如类风湿性关节炎，骨关节炎，败血症，AIDS，溃疡性结肠炎，多发性硬化，克罗恩病和退行性软骨损失。
-
公开(公告)号：WO00044716A1
公开(公告)日：2000-08-03
申请号：PCT/US2000/002143
申请日：2000-01-27
IPC: C07D295/12 , A61K20060101 , A61K31/18 , A61K31/5375 , A61P20060101 , A61P1/04 , A61P3/10 , A61P9/00 , A61P9/04 , A61P19/02 , A61P25/00 , A61P25/28 , A61P29/00 , A61P31/04 , A61P31/18 , A61P37/00 , A61P37/06 , A61P43/00 , C07B53/00 , C07C20060101 , C07C309/42 , C07C309/87 , C07C319/02 , C07C323/49 , C07C327/06 , C07C327/46 , C07D20060101 , C07F20060101 , C07F9/53
CPC classification number: C07D295/13 , C07B53/00
Abstract: Compounds of formula (B): (1a), or (1b), (1c) are provided wherein the variables are as defined herein which are useful in disease conditions mediated by TNF- alpha , such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.
Abstract translation: 提供式（B）的化合物：（1a）或（1b），（1c），其中变量如本文所定义，其可用于由TNF-α介导的疾病状态，例如类风湿性关节炎，骨关节炎，败血症，AIDS ，溃疡性结肠炎，多发性硬化，克罗恩病和退行性软骨损失。
-
24.发明申请ACETYLENIC ARYL SULFONAMIDE AND PHOSPHINIC ACID AMIDE HYDROXAMIC ACID TACE INHIBITORS 审中-公开乙酰氨基磺酰胺和磷酸酰胺类抗氧化酸性抑制剂
公开(公告)号：WO00044710A2
公开(公告)日：2000-08-03
申请号：PCT/US2000/002076
申请日：2000-01-27
IPC: C07D295/08 , A61K31/18 , A61K31/351 , A61K31/40 , A61K31/4409 , A61K31/495 , A61P1/00 , A61P1/02 , A61P1/04 , A61P1/16 , A61P5/50 , A61P7/02 , A61P9/00 , A61P9/04 , A61P9/08 , A61P9/10 , A61P13/12 , A61P17/02 , A61P17/16 , A61P19/00 , A61P19/02 , A61P19/08 , A61P25/04 , A61P25/28 , A61P27/02 , A61P27/10 , A61P29/00 , A61P31/18 , A61P35/04 , A61P37/06 , A61P43/00 , C07C303/40 , C07C309/42 , C07C309/87 , C07C311/00 , C07C311/29 , C07D213/68 , C07D295/12 , C07D309/12 , C07F9/36
CPC classification number: C07C309/42 , C07C311/29 , C07C2601/04 , C07F9/36
Abstract: Hydroxamic acids having formula (B) wherein the variables are as defined herein, are useful in treating disease conditions mediated by TNF- alpha such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.
Abstract translation: 具有式（B）的具有式（B）的羟肟酸，其变量如本文所定义，可用于治疗由TNF-α介导的疾病状况，例如类风湿性关节炎，骨关节炎，败血症，AIDS，溃疡性结肠炎，多发性硬化，克罗恩病和退行性软骨损失。
-
25.发明申请ACETYLENIC alpha -AMINO ACID-BASED SULFONAMIDE HYDROXAMIC ACID TACE INHIBITORS 审中-公开乙酰氨基酸 - 氨基酸磺酰胺羟基酸抑制剂
公开(公告)号：WO00044709A2
公开(公告)日：2000-08-03
申请号：PCT/US2000/001981
申请日：2000-01-27
IPC: A61K31/18 , A61K31/381 , A61K31/40 , A61K31/401 , A61K31/4164 , A61K31/4184 , A61K31/42 , A61K31/426 , A61K31/44 , A61K31/4406 , A61K31/4468 , A61K31/472 , A61K31/495 , A61K31/496 , A61K31/5375 , A61K31/54 , A61K31/55 , A61K31/551 , A61K31/5513 , A61K31/554 , A61P1/00 , A61P3/10 , A61P7/00 , A61P9/04 , A61P25/28 , A61P29/00 , A61P31/04 , A61P31/18 , A61P37/06 , A61P43/00 , C07C303/40 , C07C309/42 , C07C309/87 , C07C311/29 , C07C311/39 , C07C311/44 , C07C311/47 , C07C311/64 , C07C319/20 , C07C323/60 , C07D207/12 , C07D207/16 , C07D207/26 , C07D207/27 , C07D209/20 , C07D211/66 , C07D213/32 , C07D213/42 , C07D213/70 , C07D213/71 , C07D213/76 , C07D213/81 , C07D213/82 , C07D213/89 , C07D215/48 , C07D217/26 , C07D233/60 , C07D235/06 , C07D235/08 , C07D241/04 , C07D243/08 , C07D261/10 , C07D261/18 , C07D265/30 , C07D277/06 , C07D277/24 , C07D279/12 , C07D279/14 , C07D279/16 , C07D281/06 , C07D295/08 , C07D295/092 , C07D295/125 , C07D295/13 , C07D333/40 , C07D401/06 , C07D409/06 , C07D513/10 , C07D521/00 , C07C311/00
CPC classification number: C07D207/27 , C07C311/29 , C07C311/39 , C07C311/47 , C07C311/64 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07D207/12 , C07D207/16 , C07D209/20 , C07D211/66 , C07D213/32 , C07D213/42 , C07D213/70 , C07D213/71 , C07D213/81 , C07D213/82 , C07D215/48 , C07D217/26 , C07D231/12 , C07D233/56 , C07D235/06 , C07D241/04 , C07D243/08 , C07D249/08 , C07D261/18 , C07D265/30 , C07D277/06 , C07D277/24 , C07D279/12 , C07D279/14 , C07D279/16 , C07D281/06 , C07D295/088 , C07D295/125 , C07D295/13 , C07D401/06 , C07D409/06 , C07D513/10
Abstract: Compound of the formula (B) are useful in treating disease conditions mediated by TNF- alpha , such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.
Abstract translation: 式（B）的化合物可用于治疗由TNF-α介导的疾病状况，例如类风湿性关节炎，骨关节炎，败血症，AIDS，溃疡性结肠炎，多发性硬化，克罗恩病和退行性软骨损失。
-
-
-
-
Search Results
25
records
(took 0.019 seconds)
