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    Microchemical chip device
    7.
    发明专利
    Microchemical chip device 有权
    微电子芯片设备

    公开(公告)号：JP2010181253A

    公开(公告)日：2010-08-19

    申请号：JP2009024522

    申请日：2009-02-05

    申请人： Kowa Co ,  興和株式会社

    发明人： HIRONO TAIRYO

    IPC分类号： G01N33/49 ,  B01J19/00 ,  G01N37/00

    CPC分类号： B01L3/502776 ,  B01L2300/0867 ,  B01L2400/0418 ,  B01L2400/0487

    摘要： PROBLEM TO BE SOLVED: To provide a microchemical chip device capable of eliminating work to apply an agent to the wall surface of a microchannel.
    SOLUTION: As shown in Fig.2(a), two laminar flows (i.e. a particle-containing solution A
    1 and a buffer solution A
    3 ) are supplied in a microchannel 20 in a microchemical chip device, and a gel including an agent A
    2 is supplied to a location that contacts to the buffer solution A
    3 . The reaction is started by the contact of a fine particle in the particle-containing solution A
    1 to the gel including an agent A
    2 . However, the reaction is not started by the separation due to the buffer solution A
    3 in the state shown in Fig.2(a). When the buffer solution A
    3 is stopped supplying in this condition, the particle-containing solution A
    1 and the gel including an agent A
    2 are contacted each other shown in Fig.2(c), which enables fixed point observation for the reaction of the particle containing and the agent. This device, which is not necessary to apply the wall surface of the microchannel 20 and is satisfied by supplying the gel A
    2 including an agent from a supply channel 22, enables elimination of agent application.
    COPYRIGHT: (C)2010,JPO&INPIT

    摘要翻译： 要解决的问题：提供一种能够消除将试剂施加到微通道壁表面的工作的微化学芯片装置。 解决方案：如图2（a）所示，提供两个层流（即含有颗粒的溶液A 1 和缓冲溶液A 3） 在微量化学芯片装置中的微通道20中，并且将包含试剂A 2 的凝胶供给到与缓冲溶液A 3接触的位置。 通过使含有颗粒的溶液A 1 中的细颗粒与包含试剂A 2 的凝胶接触来开始反应。 但是，在图2（a）所示的状态下，由于缓冲液A 3 的分离，反应不能开始。 当在该条件下缓慢溶液A 3 停止供给时，含有颗粒的溶液A 1 和包含试剂A 2 的凝胶是 彼此接触，如图2（c）所示，这使得能够对含有颗粒和试剂的反应进行定点观察。 该装置不需要施加微通道20的壁面，并且通过从供给通道22供给包含试剂的凝胶A 2 可以消除试剂的应用。 版权所有（C）2010，JPO＆INPIT