摘要:
PROBLEM TO BE SOLVED: To provide a novel synthetic method extremely capable of being applied to an industrial preparation of an oxidized phospholipid useful for treatments.SOLUTION: There are provided a method for synthesizing 1-hexadecyl-2-(4'-carboxy)butyl-glycero-3-phosphocholine and for introducing a phosphorus-containing part such as a phosphate part into a compound having a glycerol backbone without using a column chromatography and an intermediate formed thereby.
摘要:
A microencapsulated catalyst is prepared by dissolving or dispersing a catalyst in a first phase (for example an organic phase), dispersing the first phase in a second, continuous phase (for example an aqueous phase) to form an emulsion, reacting one or more microcapsule wall-forming materials at the interface between the dispersed first phase and the continuous second phase to form a microcapsule polymer shell encapsulating the dispersed first phase core and optionally recovering the microcapsules from the continuous phase. The catalyst is preferably a transition metal catalyst and the encapsulated catalyst may be used for conventional catalysed reactions. The encapsulated catalyst may recovered from the reaction medium and re-cycled.
摘要:
Manganese(IV) complex salts of formula [LMn(mu-O) 3 MnL] n [XM 12 O 40 ] m , (I), wherein L is 1,4,7-trimethyl-1,4,7-triazacyclononane, X is P or Si, M is Mo or W, n is 2 or 3, and m is 1 or 2, with the provisos that (i) if X is Si, then n=2 and m=1 and (ii) if X is P, then n=3 and m=2. These compounds are active catalysts in the partial oxidation of various organic compounds with peroxy compounds, e.g., the preparation of ketones from secondary alcohols or the epoxidation of olefins.
摘要:
Osmium-catalyzed methods of addition to an olefin are discussed. In the method of asymmetric dihydroxylation of the present invention, an olefin, a chiral ligand, an organic solvent, water, an oxidant and an osmium-containing compound are combined. In the method of asymmetric oxyamination of the present invention, an olefin, a chiral ligand, an organic solvent, water, a metallochloramine derivative, an osmium-containing compound and, optionally, a tetraalkyl ammonium compound are combined. In the method of asymmetric diamination of the present invention, an olefin, a chiral ligand, an organic solvent, a metallo-chloramine derivative, an amine and an osmium-containing compound are combined. In one embodiment, an olefin, a chiral ligand which is a polymeric dihydroquinidine derivative or a dihydroquinine derivative, acetone, water, a base, an oxidant and osmium tetroxide are combined to effect asymmetric dihydroxylation of the olefin.