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    Detection of connection and disconnection of computer peripheral
    1.
    发明申请
    Detection of connection and disconnection of computer peripheral 有权
    检测计算机外围设备的连接和断开

    公开(公告)号：US20060152381A1

    公开(公告)日：2006-07-13

    申请号：US11026569

    申请日：2004-12-30

    Applicant: Xiaoping Yang ,  Kenny He

    Inventor： Xiaoping Yang ,  Kenny He

    IPC: G08B21/00

    CPC classification number: G08B13/1409 ,  G08B13/1463

    Abstract: In some embodiments a connector is to couple a peripheral, and a detector coupled to the connector is to detect if the peripheral is disconnected from the connector in response to a first reserved pin and a second reserved pin. Other embodiments are described and claimed.

    Abstract translation: 在一些实施例中，连接器用于耦合外围设备，并且耦合到连接器的检测器响应于第一保留引脚和第二保留引脚来检测外围设备是否与连接器断开连接。 描述和要求保护其他实施例。

    Sensor molecules incorporating a boronic acid sensor group
    2.
    发明授权
    Sensor molecules incorporating a boronic acid sensor group 有权
    掺入硼酸传感器组的传感器分子

    公开(公告)号：US08227254B2

    公开(公告)日：2012-07-24

    申请号：US11814965

    申请日：2006-01-31

    Applicant: Christopher Robin Lowe ,  Felicity Kate Sartain ,  Xiaoping Yang

    Inventor： Christopher Robin Lowe ,  Felicity Kate Sartain ,  Xiaoping Yang

    IPC: G01N33/00 ,  C07C233/29 ,  C07C63/66 ,  C40B40/04 ,  C08F30/06 ,  B44F1/00 ,  G03F7/00 ,  G02B5/32

    CPC classification number: G01N33/5308 ,  Y10T436/201666

    Abstract: The present invention pertains to compounds and polymers which incorporate a boronic acid sensor group (SG) of the formula (I): wherein: J is independently —CH2— or —CH2CH2—; n is independently 0, 1, 2, or 3; and each RR, if present, is independently a ring substituent; and wherein the ring attachment (i.e., where sensor group is attached) is via the 3-, 4-, 5-, or 6-ring position. Such compounds and polymers are useful in the selective chemical detection and/or quantitation of alpha-hydroxy carboxylic acids, such as lactic acid/lactate and malic acid/malate. The present invention also pertains to methods of preparing such compounds and polymers; methods and assays which employ these compounds and polymers; devices (e.g., holographic sensors) and kits for use in such methods and assays, etc.

    Abstract translation: 本发明涉及结合式（I）的硼酸传感器组（SG）的化合物和聚合物：其中：J独立地是-CH 2 - 或-CH 2 CH 2 - ; n独立地为0,1,2或3; 并且每个RR（如果存在的话）独立地是环取代基; 并且其中环附件（即，传感器组附接的位置）经由3-，4-，5-或6-环位置。 这些化合物和聚合物可用于α-羟基羧酸如乳酸/乳酸和苹果酸/苹果酸的选择性化学检测和/或定量。 本发明还涉及制备这种化合物和聚合物的方法; 使用这些化合物和聚合物的方法和测定法; 设备（如全息传感器）和用于此类方法和测定等的试剂盒

    Tire with component comprised of a blend of polybutadiene rubber and composite of styrene/butadiene elastomer which contains exfoliated clay platelets
    3.
    发明授权
    Tire with component comprised of a blend of polybutadiene rubber and composite of styrene/butadiene elastomer which contains exfoliated clay platelets 失效
    轮胎与由聚丁二烯橡胶和苯乙烯/丁二烯弹性体的混合物组成的组合物，其中含有剥离的粘土片晶

    公开(公告)号：US07714055B2

    公开(公告)日：2010-05-11

    申请号：US10923911

    申请日：2004-08-23

    Applicant: David John Zanzig ,  Xiaoping Yang ,  Martin Paul Cohen

    Inventor： David John Zanzig ,  Xiaoping Yang ,  Martin Paul Cohen

    IPC: B60C1/00 ,  C08K3/34 ,  C08K3/04

    CPC classification number: C08K3/346 ,  B60C1/0016 ,  C08K3/013 ,  C08K5/548 ,  C08K9/04 ,  C08L9/00 ,  C08L9/06 ,  Y10S152/905 ,  C08L2666/08 ,  C08L21/00

    Abstract: Pneumatic rubber tire having at least one component of a polybutadiene-rich rubber composition comprised of a blend of a continuous phase of a specialized cis 1,4-polybutadiene rubber and a dispersed phase comprised of a composite of styrene/butadiene elastomer which contains a dispersion of at least partially exfoliated, intercalated, clay platelets, wherein said cis 1,4-polybutadiene rubber and styrene/butadiene elastomer have spatially defined glass transition temperatures, wherein said blend contains amorphous silica and carbon black reinforcement. Such tire component may be, for example, a circumferential tread having a running surface intended to be ground-contacting or a sidewall insert.

    Abstract translation: 气动橡胶轮胎具有至少一种含聚丁二烯的橡胶组合物的组分，其由特殊的顺式1,4-聚丁二烯橡胶的连续相的共混物和由含有分散体的苯乙烯/丁二烯弹性体的复合物组成的分散相组成 的至少部分剥离的，插入的粘土片晶，其中所述顺式1,4-聚丁二烯橡胶和苯乙烯/丁二烯弹性体具有空间限定的玻璃化转变温度，其中所述共混物包含无定形二氧化硅和炭黑增强物。 这种轮胎部件可以是例如具有旨在被接地的行进面或侧壁插入物的周向胎面。

    Sensor Molecules Incorporating a Boronic Acid Sensor Group
    5.
    发明申请
    Sensor Molecules Incorporating a Boronic Acid Sensor Group 有权
    传感器分子纳入硼酸传感器组

    公开(公告)号：US20080160225A1

    公开(公告)日：2008-07-03

    申请号：US11814965

    申请日：2006-01-31

    Applicant: Christopher Robin Lowe ,  Felicity Kate Sartain ,  Xiaoping Yang

    Inventor： Christopher Robin Lowe ,  Felicity Kate Sartain ,  Xiaoping Yang

    IPC: G01N33/00 ,  C07C233/29 ,  C07C63/66 ,  C40B40/04 ,  C08F30/06 ,  B44F1/00 ,  G03F7/00 ,  G02B5/32

    CPC classification number: G01N33/5308 ,  Y10T436/201666

    Abstract: The present invention pertains to compounds and polymers which incorporate a boronic acid sensor group (SG) of the formula (I): wherein: J is independently —CH2— or —CH2CH2—; n is independently 0, 1, 2, or 3; and each RR, if present, is independently a ring substituent; and wherein the ring attachment (i.e., where sensor group is attached) is via the 3-, 4-, 5-, or 6-ring position. Such compounds and polymers are useful in the selective chemical detection and/or quantitation of alpha-hydroxy carboxylic acids, such as lactic acid/lactate and malic acid/malate. The present invention also pertains to methods of preparing such compounds and polymers; methods and assays which employ these compounds and polymers; devices (e.g., holographic sensors) and kits for use in such methods and assays, etc.

    Abstract translation: 本发明涉及结合式（I）的硼酸传感器组（SG）的化合物和聚合物：其中：J独立地是-CH 2 - 或-CH 2， 2→CH 2 - ; n独立地为0,1,2或3; 如果存在的话，每个R“R”独立地是环取代基; 并且其中环附件（即，传感器组附接的位置）经由3-，4-，5-或6-环位置。 这些化合物和聚合物可用于α-羟基羧酸如乳酸/乳酸和苹果酸/苹果酸的选择性化学检测和/或定量。 本发明还涉及制备这种化合物和聚合物的方法; 使用这些化合物和聚合物的方法和测定法; 设备（如全息传感器）和用于此类方法和测定等的试剂盒

    Holographic Sensor
    8.
    发明申请
    Holographic Sensor 审中-公开
    全息传感器

    公开(公告)号：US20120107944A1

    公开(公告)日：2012-05-03

    申请号：US13284094

    申请日：2011-10-28

    Applicant: Christopher Robin Lowe ,  Jeffrey Blyth ,  Satyamoorthy Kabilan ,  Abid Hussain ,  Xiaoping Yang ,  Felicity Kate Sartain ,  Mei-Ching Lee

    Inventor： Christopher Robin Lowe ,  Jeffrey Blyth ,  Satyamoorthy Kabilan ,  Abid Hussain ,  Xiaoping Yang ,  Felicity Kate Sartain ,  Mei-Ching Lee

    IPC: G01N33/66

    CPC classification number: G03H1/02 ,  G02B5/32 ,  G03H2260/12 ,  Y10T436/143333 ,  Y10T436/144444

    Abstract: A sensor for the detection of an analyte comprising a cis-diol moiety, which comprises a holographic element comprising a medium and a hologram disposed throughout the volume of the medium, wherein an optical characteristic of the element changes as a result of a variation of a physical property occurring throughout the volume of the medium, and wherein the medium is a polymer comprising a group of formula (i) wherein n is 0, 1, 2, 3 or 4; each X (if present) is independently is an atom or group which, via an electronic effect, promotes formation of a tetrahedral geometry about the boron atom; and Y is a spacer which, when n is 0 or otherwise optionally, is an atom or group which, via an electronic effect, promotes formation of a tetrahedral geometry about the boron atom. Such a sensor may be used for the detection of glucose.

    Abstract translation: 一种用于检测包含顺式二醇部分的分析物的传感器，其包括全息元件，该全息元件包括介质和设置在介质的整个体积中的全息图，其中该元件的光学特性由于 介质是包含其中n为0,1,2,3或4的式（ⅰ）基团的聚合物; 每个X（如果存在）独立地是通过电子效应促进形成围绕硼原子的四面体几何形状的原子或基团; 并且Y是间隔基，当n为0或以其它方式任选时，其是通过电子效应促进围绕硼原子形成四面体几何形状的原子或基团。 这种传感器可用于检测葡萄糖。

    Method of producing short hairpin library
    10.
    发明申请
    Method of producing short hairpin library 审中-公开
    短发夹文库的生产方法

    公开(公告)号：US20070141594A1

    公开(公告)日：2007-06-21

    申请号：US11546019

    申请日：2006-10-11

    Applicant: Biao Luo ,  David Root ,  Xiaoping Yang ,  Gregory Hinkle

    Inventor： Biao Luo ,  David Root ,  Xiaoping Yang ,  Gregory Hinkle

    IPC: C40B40/08 ,  C40B50/06

    CPC classification number: C12N15/1093 ,  C12N15/111 ,  C12N2310/14 ,  C12N2310/53 ,  C12N2330/31

    Abstract: Described herein is a method of cloning synthetic oligos (including in situ synthesized oligos) into an (one or more) expression vector for library (e.g., shRNA library) production. The oligos are synthesized with one portion of the first stem of the hairpin, followed by a first loop sequence, the complete second stem, a second loop sequence, and finished with the remaining portion of the first stem of the hairpin. The two portions of the first stem anneal to the second stem, juxtaposing the 5′ end close to the 3′ end of the oligo. The methods described herein selected for hairpins with perfectly base-paired stems. After annealing, a ligase is added to the annealed oligos and the base-paired hairpins are preferentially annealed, and ligated, creating closed circular oligos. The now circularized hairpins served as templates for rolling circle amplification using a polymerase with high processivity. One or more primers complementary to the two strands of the amplified double stranded circular hairpins initiate the rolling circle amplification in the presence of a polymerase. Using primers (e.g., a sense and antisense primer), the rolling circle amplification yields double stranded hairpin sequences. These can be digested (e.g., using restriction enzymes) to produce a double-stranded hairpin fragment encoding a single hairpin. The fragment can be cloned into an appropriately digested vector for a variety of uses including expression.

    Abstract translation: 本文描述了将合成寡核苷酸（包括原位合成的寡核苷酸）克隆到（一个或多个）用于文库（例如shRNA文库）生产的表达载体中的方法。 寡核苷酸与发夹的第一茎的一部分合成，随后是第一环序列，完整的第二茎，第二环序列，并用发夹的第一茎的剩余部分完成。 第一茎的两个部分与第二茎退火，将5'末端与寡核苷酸的3'末端并列。 本文所述的方法选择用于具有完全碱基配对茎的发夹。 退火后，将连接酶加入到退火的寡核苷酸中，并且将碱基配对的发夹优先退火并连接，产生闭合的环状寡核苷酸。 现在的圆形发夹作为使用高活性的聚合酶进行滚环扩增的模板。 与扩增的双链环状发夹的两条链互补的一个或多个引物在聚合酶存在下引发滚环扩增。 使用引物（例如有义和反义引物），滚环扩增产生双链发夹序列。 这些可以被消化（例如，使用限制酶）以产生编码单个发夹的双链发夹片段。 可以将片段克隆到适当消化的载体中，用于多种用途，包括表达。

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