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公开(公告)号：US10427131B2
公开(公告)日：2019-10-01
申请号：US15555679
申请日：2016-03-15
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar , George W. Griesgraber
IPC: B01J20/10 , B01J20/22 , B01J20/28 , B01J20/32 , G01N33/543 , G01N33/552 , G01N33/569
Abstract: Guanidine-functionalized perlite particles are provided. Nonwoven articles are also provided, including a fibrous porous matrix and guanidine-functionalized perlite particles enmeshed in the fibrous porous matrix. Laminated articles are additionally provided, including a first substrate and a second substrate sealed to the first substrate along at least a portion of a perimeter of the first substrate. The laminated article further includes guanidine-functionalized perlite particles disposed between the first substrate and the second substrate. Methods of detecting microorganisms or target cellular analytes in a fluid sample using guanidine-functionalized particles or laminated articles are also provided.
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公开(公告)号：US10413881B2
公开(公告)日：2019-09-17
申请号：US15039664
申请日：2014-12-16
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar , Hassan Sahouani
IPC: B01D15/00 , B01J20/26 , B01J20/28 , B01J20/30 , C08F2/44 , C08J9/16 , C08J9/26 , C08J9/28 , C08F220/12 , C08F220/18 , C12Q1/10
Abstract: Porous articles are provided that include a fibrous porous matrix and porous polymeric particles. The porous polymeric particles are distributed throughout the fibrous porous polymeric matrix. The porous article can be used to prepare a separation device or a system that includes the separation device. The porous articles can be used for the separation of a target material such as a microorganism (i.e., cellular analyte) from a sample.
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公开(公告)号：US20170248503A1
公开(公告)日：2017-08-31
申请号：US15594431
申请日：2017-05-12
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar , Kurt J. Halverson , Raj Rajagopal
IPC: G01N1/40
Abstract: Kits and systems for isolating microorganisms from a sample, the sample including sample matrix and microorganisms, the kit including concentration agent; and a system for isolating microorganisms from a sample.
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4.发明申请GUANIDINE-FUNCTIONALIZED METAL SILICATE PARTICLES AND METHODS OF MAKING AND USING SUCH PARTICLES 审中-公开官能官能化金属硅酸盐颗粒及其制备和使用这种颗粒的方法公开(公告)号：US20160209305A1
公开(公告)日：2016-07-21
申请号：US14914017
申请日：2014-06-04
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar , George W. Griesgraber
CPC classification number: G01N1/4077 , B01D39/06 , C01B33/20 , C01B33/22 , C01B33/26 , C07F7/10 , C12Q1/24 , D04H13/00 , D10B2403/02421 , G01N2001/4088 , G01N2333/245
Abstract: Guanidine-functionalized particles and methods of making and using such particles are provided, such as guanidine-functionalized metal silicate particles. A nonwoven article is also provided including a porous fibrous nonwoven matrix and guanidine-functionalized metal silicate particles enmeshed within the porous fibrous nonwoven matrix. The nonwoven article may be used, for instance, for removing microorganisms from an aqueous sample by contacting a fluid sample with the nonwoven article such that at least a portion of the microorganisms are removed from the fluid sample.
Abstract translation: 胍官能化颗粒以及制造和使用这些颗粒的方法，例如胍官能化的金属硅酸盐颗粒。 还提供了一种非织造制品，其包括多孔纤维非织造基体和包含在多孔纤维非织造基质内的胍官能化金属硅酸盐颗粒。 非织造制品可以用于例如通过使流体样品与非织造制品接触从而从水样品中除去微生物，使得至少一部分微生物从流体样品中除去。
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公开(公告)号：US09351797B2
公开(公告)日：2016-05-31
申请号：US14042754
申请日：2013-10-01
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： G. Marco Bommarito , Manjiri T. Kshirsagar , Ting Liu , Timothy J. Nies , Swarnalatha Swaminathan
CPC classification number: C12Q1/66 , A61B90/70 , A61B2090/702 , A61L2/28 , C12Q1/22 , C12Y113/12007 , G01N2333/90241 , Y10T436/13
Abstract: The present disclosure provides a monitoring device comprising a test composition, a test element comprising a test portion to which the test composition is releasably adhered, a detection reagent, and a container comprising a first end with an opening and a second end opposite the first end. The test composition comprises a predetermined quantity of tracer analyte. The container is configured to receive the test portion and configured to be operationally coupled to an analytical instrument. The tracer analyte and the detection reagent each are capable of participating in one or more chemical reaction that results in the formation of a detectable product. A method of using the monitoring device to assess the efficacy of a washing process is also provided.
Abstract translation: 本公开提供了一种监测装置，其包括测试组合物，测试元件，其包括测试组合物可释放地粘附到其上的测试部分，检测试剂和包含具有开口的第一端和与第一端相对的第二端的容器 。 测试组合物包含预定量的示踪剂分析物。 容器被配置为接收测试部分并且被配置为可操作地耦合到分析仪器。 示踪剂分析物和检测试剂各自能够参与导致形成可检测产物的一种或多种化学反应。 还提供了使用监测装置来评估洗涤过程的功效的方法。
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Patent Agency Ranking
公开(公告)号：US20180224360A1
公开(公告)日：2018-08-09
申请号：US15945228
申请日：2018-04-04
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar , Andrew W. Rabins
IPC: G01N1/40
Abstract: A process for capturing or concentrating microorganisms for detection or assay comprises (a) providing a concentration device comprising a sintered porous polymer matrix comprising at least one concentration agent that comprises diatomaceous earth bearing, on at least a portion of its surface, a surface treatment comprising a surface modifier comprising ferric oxide, titanium dioxide, fine-nanoscale gold or platinum, or a combination thereof; (b) providing a sample comprising at least one microorganism strain; and (c) contacting the concentration device with the sample such that at least a portion of the at least one microorganism strain is bound to or captured by the concentration device.
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公开(公告)号：US20180051313A1
公开(公告)日：2018-02-22
申请号：US15556664
申请日：2016-03-15
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Raj Rajagopal , Manjiri T. Kshirsagar , Evan D. Brutinel , James E. Aysta
CPC classification number: C12Q1/24 , B01D46/00 , C12M1/12 , C12M1/26 , C12M1/34 , C12Q1/04 , G01N1/10 , G01N1/405 , G01N2001/4088
Abstract: Methods of detecting microorganisms in a fluid sample are provided. The method includes providing a nonwoven article, providing a fluid sample suspected of containing at least one microorganism strain or target cellular analyte, and contacting the fluid sample with the nonwoven article such that at least a portion of the at least one microorganism strain or target cellular analyte is bound to the nonwoven article. The nonwoven article includes a fibrous porous matrix and a concentration agent particles enmeshed in the fibrous porous matrix. The method further includes placing the microorganism strain- or target cellular analyte-bound nonwoven article in contact with at least one detection reagent and detecting the presence of the bound microorganism strain or bound target cellular analyte. Devices and kits containing the devices, for contacting a fluid sample with a nonwoven article, are also provided. The device includes a sample container, a filter holder, a nonwoven article, and an adaptor configured to interface the filter holder with a receptacle.
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8.发明申请公开(公告)号：US20180051312A1
公开(公告)日：2018-02-22
申请号：US15559117
申请日：2016-03-18
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Jobst T. Jaeger , Jeffrey D. Smith , Waleri Wischnepolski , Henning Reuter , Giuseppe M. Bommarito , Manjiri T. Kshirsagar , Scott D. Lehman , Edward I. Stamm, Jr. , Guenter M. Zilligen
IPC: C12Q1/22 , B01L3/02 , B01L3/00 , C12Q1/04 , G01N33/543
CPC classification number: C12Q1/22 , B01L3/0275 , B01L3/5029 , B01L2200/028 , B01L2200/0684 , B01L2300/0681 , B01L2300/123 , B01L2400/0478 , B01L2400/0605 , C12Q1/04 , G01N33/54386
Abstract: Devices for detecting microorganism strains or target cellular analytes are provided. The device includes a filter holder, the filter holder comprising a tip portion; a nonwoven article disposed on the tip portion of the filter holder; and an adaptor attacked to the filter holder, the adaptor defining an aperture. Methods of detecting microorganisms and/or cellular analytes in a fluid sample using the devices are also provided. The method includes obtaining the device; placing a lumened or cannulated device in fluid communication with the device; and passing a fluid sample suspected of containing at least one microorganism strain or target cellular analyte from the lumened or cannulated device through the device and contacting the nonwoven article. The method further includes contacting the nonwoven article with at least one detection reagent and detecting the presence of the at least one microorganism strain or target cellular analyte concentrated by the nonwoven article. Kits and systems including the devices are also provided.
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9.发明申请公开(公告)号：US20180038862A1
公开(公告)日：2018-02-08
申请号：US15555679
申请日：2016-03-15
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar , George W. Griesgraber
IPC: G01N33/569 , B01J20/28 , B01J20/10 , B01J20/22 , G01N33/543 , G01N33/552
CPC classification number: G01N33/569 , B01J20/106 , B01J20/22 , B01J20/28026 , B01J20/28035 , B01J20/3204 , B01J20/3259 , G01N33/54313 , G01N33/54353 , G01N33/552 , G01N33/56916 , G01N33/56938
Abstract: Guanidine-functionalized perlite particles are provided. Nonwoven articles are also provided, including a fibrous porous matrix and guanidine-functionalized perlite particles enmeshed in the fibrous porous matrix. Laminated articles are additionally provided, including a first substrate and a second substrate sealed to the first substrate along at least a portion of a perimeter of the first substrate. The laminated article further includes guanidine-functionalized perlite particles disposed between the first substrate and the second substrate. Methods of detecting microorganisms or target cellular analytes in a fluid sample using guanidine-functionalized particles or laminated articles are also provided.
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公开(公告)号：US20170176426A1
公开(公告)日：2017-06-22
申请号：US15450085
申请日：2017-03-06
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar , Tushar A. Kshirsagar , Thomas E. Wood
IPC: G01N33/543 , G01N33/552 , G01N33/553
CPC classification number: G01N33/54313 , C12N1/02 , C12N11/14 , C12Q1/04 , C12Q1/24 , G01N33/552 , G01N33/553
Abstract: A process for capturing or concentrating microorganisms for detection or assay comprises (a) providing a concentration agent that comprises an amorphous metal silicate and that has a surface composition having a metal atom to silicon atom ratio of less than or equal to about 0.5, as determined by X-ray photoelectron spectroscopy (XPS); (b) providing a sample comprising at least one microorganism strain; and (c) contacting the concentration agent with the sample such that at least a portion of the at least one microorganism strain is bound to or captured by the concentration agent.
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