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公开(公告)号：US20170267716A1
公开(公告)日：2017-09-21
申请号：US15071210
申请日：2016-03-16
Applicant: General Electric Company
Inventor： Anthony John Murray , Andrew David Pris , Erik Leeming Kvam , Nandini Nagraj , Eugene Pauling Boden , Ernest William Kovacs , Louisa Ruth Carr , Rui Chen , Tiberiu Mircea Siclovan , Kelly Scott Chichak
IPC: C07K1/36 , C07K16/00 , C12N9/74 , C12N15/115 , C07K14/705
CPC classification number: C07K1/36 , C07K1/32 , C07K14/70564 , C07K16/4291 , C12N9/6429 , C12Y304/21005
Abstract: Provided herein are aptamer-polymer conjugates which are responsive to environmental stimuli and are useful in selective purification of untagged target polypeptides.
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公开(公告)号：US20160313318A1
公开(公告)日：2016-10-27
申请号：US15204666
申请日：2016-07-07
Applicant: General Electric Company
Inventor： An-Ping Zhang , Anthony John Murray , Rui Chen
IPC: G01N33/543 , G01N33/545
CPC classification number: G01N33/54373 , B82Y15/00 , B82Y40/00 , G01N27/327 , G01N27/4145 , G01N27/4146 , G01N33/545
Abstract: A biosensing FET device, comprising a plurality of nanostructured SOI channels, that is adapted to operate in solutions having a high ionic strength and provides improves sensitivity and detection. Generally, the biosensing device comprises an underlying substrate layer, an insulator and a semiconductor layer and a plurality of channels in the semiconductor layer comprising a plurality of whole or partially formed nanopores in the channels.
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3.发明申请METHOD FOR STERILIZING MEMBRANE COMPRISING AND OXIDOREDUCTASE ENZYME AND ASSOCIATED BIOSENSOR 有权灭菌膜和氧化还原酶和相关生物传感器的方法公开(公告)号：US20150151013A1
公开(公告)日：2015-06-04
申请号：US14402473
申请日：2013-05-29
Applicant: GENERAL ELECTRIC COMPANY
CPC classification number: A61L2/081 , A61L2/0035 , C12Q1/005 , C12Q1/006 , C12Q1/26 , C12Q1/54 , G01N2333/904
Abstract: A method for sterilizing a membrane comprising an oxidoreductase enzyme in an environment having a relative humidity, comprises: irradiating the membrane comprising an oxidoreductase enzyme with gamma radiation under vacuum at a relative humidity lower than the relative humidity of the environment. Associated biosensors are also described.
Abstract translation: 在具有相对湿度的环境中对包含氧化还原酶的膜进行灭菌的方法包括：在低于环境相对湿度的相对湿度下，在真空下照射含有氧化还原酶的膜。 还描述了相关生物传感器。
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公开(公告)号：US10481222B2
公开(公告)日：2019-11-19
申请号：US15658123
申请日：2017-07-24
Applicant: General Electric Company
Inventor： Ernst Wolfgang Stautner , Jan Henrik Ardenkjaer-Larsen , Patrick L. Padgett , Jonathan Alan Murray , Rui Chen , James Richard Trigger , Arnaud Comment , Albert Po-Fu Chen
Abstract: A cooling system is provided. The cooling system is associated with a dynamic nuclear polarization system and configured to cool a sample to a temperature suitable for dynamic nuclear polarization to be carried out on the sample while the sample is in the cooling system. The cooling system includes a cryogenic chamber that includes a cryogenic fluid. The cooling system also includes a removable sample sleeve insertable within a portion of the cryogenic chamber. The removable sample sleeve is configured to define a sample path for the sample within the cryogenic chamber that is isolated from other parts of the cooling system.
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公开(公告)号：US09829474B2
公开(公告)日：2017-11-28
申请号：US14884992
申请日：2015-10-16
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Rui Chen , Andrew Michael Leach , Manuel Alfred Palacios
CPC classification number: G01N33/15 , C07F15/025 , G01N21/31
Abstract: The present invention is directed to methods of acetate quantification and acetate complexes useful in the methods of acetate quantification. Such methods and complexes are useful for any application where acetate quantification is desired, including measuring of concentration of 13C hyperpolarized acetate for imaging agent quality control in MRI and NMR spectroscopy. The disclosed acetate complexes may be prepared from acetate, Fe3+, and sulfosalicylic acid and from acetate, Fe3+, and salicylic acid.
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Patent Agency Ranking
6.发明申请METHOD FOR STERILIZING MEMBRANE COMPRISING GLUCOSE OXIDASE AND ASSOCIATED BIO-SENSOR 审中-公开消毒含有葡萄糖氧化酶和相关生物传感器的膜的灭菌方法公开(公告)号：US20150157750A1
公开(公告)日：2015-06-11
申请号：US14402453
申请日：2013-05-29
Applicant: GENERAL ELECTRIC COMPANY
CPC classification number: A61L2/081 , A61L2/0035 , C12M41/32 , C12Q1/006 , C12Q1/26
Abstract: A method for sterilizing a membrane comprising an oxidoreductase enzyme, comprises: irradiating with gamma radiation the membrane comprising an oxidoreductase enzyme soaked in an aqueous buffer solution. Associated biosensors and bioreactors are also described.
Abstract translation: 一种对包含氧化还原酶的膜进行灭菌的方法，包括：用γ辐射照射包含浸在缓冲液水溶液中的氧化还原酶的膜。 还描述了相关的生物传感器和生物反应器。
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公开(公告)号：US20180154026A1
公开(公告)日：2018-06-07
申请号：US15884310
申请日：2018-01-30
Applicant: General Electric Company
CPC classification number: A61L2/081 , A61L2/0035 , C12M41/32 , C12Q1/006 , C12Q1/26
Abstract: A method for sterilizing a membrane comprising an oxidoreductase enzyme, comprises: irradiating with gamma radiation the membrane comprising an oxidoreductase enzyme soaked in an aqueous buffer solution. Associated biosensors and bioreactors are also described.
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公开(公告)号：US10369238B2
公开(公告)日：2019-08-06
申请号：US15884310
申请日：2018-01-30
Applicant: General Electric Company
Abstract: A method for sterilizing a membrane comprising an oxidoreductase enzyme, comprises: irradiating with gamma radiation the membrane comprising an oxidoreductase enzyme soaked in an aqueous buffer solution. Associated biosensors and bioreactors are also described.
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公开(公告)号：US20190025387A1
公开(公告)日：2019-01-24
申请号：US15658123
申请日：2017-07-24
Applicant: General Electric Company
Inventor： Ernst Wolfang Stautner , Jan Henrik Ardenkjaer-Larsen , Patrick L. Padgett , Jonathan Alan Murray , Rui Chen , James Richard Trigger , Arnaud Comment , Albert Po-Fu Chen
CPC classification number: G01R33/31 , F25B19/005 , F25D19/006 , F25D21/002 , F25D29/001 , G01N1/42 , G01R33/282
Abstract: A cooling system is provided. The cooling system is associated with a dynamic nuclear polarization system and configured to cool a sample to a temperature suitable for dynamic nuclear polarization to be carried out on the sample while the sample is in the cooling system. The cooling system includes a cryogenic chamber that includes a cryogenic fluid. The cooling system also includes a removable sample sleeve insertable within a portion of the cryogenic chamber. The removable sample sleeve is configured to define a sample path for the sample within the cryogenic chamber that is isolated from other parts of the cooling system.
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10.发明授权公开(公告)号：US09968696B2
公开(公告)日：2018-05-15
申请号：US14402473
申请日：2013-05-29
Applicant: GENERAL ELECTRIC COMPANY
CPC classification number: A61L2/081 , A61L2/0035 , C12Q1/005 , C12Q1/006 , C12Q1/26 , C12Q1/54 , G01N2333/904
Abstract: A method for sterilizing a membrane comprising an oxidoreductase enzyme in an environment having a relative humidity, comprises: irradiating the membrane comprising an oxidoreductase enzyme with gamma radiation under vacuum at a relative humidity lower than the relative humidity of the environment. Associated biosensors are also described.
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