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    Applications of hyperspectral laser speckle imaging
    1.
    发明申请
    Applications of hyperspectral laser speckle imaging 有权
    超光谱激光斑点成像的应用

    公开(公告)号：US20160198961A1

    公开(公告)日：2016-07-14

    申请号：US14596952

    申请日：2015-01-14

    Applicant: Google Inc.

    Inventor： Andrew Homyk ,  Jason Donald Thompson

    IPC: A61B5/026 ,  A61B5/00

    CPC classification number: A61B5/0075 ,  A61B5/0066 ,  A61B5/0082 ,  A61B5/0261 ,  A61B5/681 ,  A61B5/72

    Abstract: Systems and methods are provided for detecting the flow of blood or other fluids in biological tissue by illuminating the biological tissue with two or more beams of coherent light and detecting responsively emitted light. A difference in wavelength, coherence length, beam divergence, or some other property of the beams of illumination causes the beams to preferentially scatter from, be absorbed by, or otherwise interact with respective elements of the biological tissue. Flow properties in one or more regions of the biological tissue (e.g., a region with which both beams of light preferentially interact, a region with which only one of the beams preferentially interacts) could be determined based on detected responsively emitted light from the biological tissue. Variations in speckle patterns over time and/or space, Doppler shifts, or some other properties of the detected light could be used to determine the flow properties.

    Abstract translation: 提供了用于通过用两个或更多个相干光束照射生物组织并检测响应性发射的光来检测生物组织中血液或其它流体的流动的系统和方法。 波长，相干长度，光束发散或照明光束的某些其他特性的差异导致光束优先从生物组织的相应元件散射，被其吸收或以其他方式相互作用。 可以基于检测到的来自生物组织的响应发射光来确定生物组织的一个或多个区域（例如，两个光束优先相互作用的区域，只有一个光束优先相互作用的区域）的流动特性 。 随着时间和/或空间的斑点图案的变化，多普勒频移或检测到的光的某些其他特性可用于确定流动特性。

    Positioning a wearable device for data collection
    2.
    发明申请
    Positioning a wearable device for data collection 有权
    定位用于数据收集的可穿戴设备

    公开(公告)号：US20160007925A1

    公开(公告)日：2016-01-14

    申请号：US14329341

    申请日：2014-07-11

    Applicant: Google Inc.

    Inventor： Russell Norman Mirov ,  Andrew Homyk ,  Mark West Askew ,  Jason Donald Thompson

    IPC: A61B5/00 ,  G01B11/14

    CPC classification number: A61B5/00 ,  A61B5/0022 ,  A61B5/0059 ,  A61B5/02427 ,  A61B5/489 ,  A61B5/6801 ,  A61B5/6802 ,  A61B5/681 ,  A61B5/70 ,  A61B2562/043 ,  G01B11/14

    Abstract: Wearable devices are described herein including at least two photodetectors and a mount configured to mount the at least two photodetectors to an external surface of a wearer. The at least two photodetectors are configured to detect alignment between the wearable device and a target on or in the body of the wearer (e.g., to detect the location of vasculature within the body of the wearer relative to the at least two photodetectors). Alignment of the at least two photodetectors relative to the target could enable detection of one or more physiological properties of the wearer. For example, the wearable device could include a sensor configured to detect a property of the target when the sensor is above the target, and alignment of the target relative to the at least two photodetectors could include the sensor being located above the target.

    Abstract translation: 本文描述了可穿戴设备，其包括至少两个光电检测器和被配置为将至少两个光电检测器安装到穿戴者的外表面的安装座。 所述至少两个光电检测器被配置为检测穿戴式装置与佩戴者身体上或身体中的目标之间的对准（例如，以相对于至少两个光电探测器检测穿戴者身体内脉管系统的位置）。 至少两个光电检测器相对于目标的对准可以使得能够检测穿戴者的一个或多个生理特性。 例如，可穿戴设备可以包括传感器，其被配置为当传感器在目标上方时检测目标的属性，并且目标相对于至少两个光电检测器的对准可以包括位于目标上方的传感器。

    Pressure Wave Measurement of Blood Flow
    3.
    发明申请
    Pressure Wave Measurement of Blood Flow 审中-公开
    血流压力波测量

    公开(公告)号：US20160106326A1

    公开(公告)日：2016-04-21

    申请号：US14519765

    申请日：2014-10-21

    Applicant: Google Inc.

    Inventor： Vikram Singh Bajaj ,  Andrew Homyk

    IPC: A61B5/0285 ,  A61B5/00 ,  A61B8/06

    CPC classification number: A61B5/0285 ,  A61B5/6824 ,  A61B5/7278 ,  A61B8/06 ,  A61B8/4227 ,  A61B8/4477 ,  A61B8/5207

    Abstract: Methods and devices for measuring blood flow velocity are provided. The device may include a wave source and at least two detectors positioned along a blood vessel. The wave source, which may include an ultrasound transducer or a mechanical source, is configured to induce a pressure wave in blood flowing in a blood vessel. In one example, the detectors are both positioned downstream of the wave source, with respect to the direction of blood flow. In another example, one detector is positioned upstream of the wave source, and a second detector is positioned downstream of the wave source. The difference in time it takes for the induced pressure wave to reach the first and the second detectors is indicative of the velocity of blood flow in the vessel.

    Abstract translation: 提供了测量血流速度的方法和装置。 该装置可以包括波源和沿血管定位的至少两个检测器。 可以包括超声换能器或机械源的波源被配置为在血管中流动的血液中引起压力波。 在一个示例中，检测器相对于血流的方向都位于波源的下游。 在另一示例中，一个检测器位于波源的上游，并且第二检测器位于波源的下游。 诱导压力波到达第一和第二检测器所需的时间差异表示血管中血流的速度。

    Engineered Particles with Polarization Contrast and Alignment Control for Enhanced Imaging
    4.
    发明申请
    Engineered Particles with Polarization Contrast and Alignment Control for Enhanced Imaging 有权
    具有极化对比度和对准控制的工程粒子，用于增强成像

    公开(公告)号：US20150238636A1

    公开(公告)日：2015-08-27

    申请号：US14188634

    申请日：2014-02-24

    Applicant: Google Inc.

    Inventor： Andrew Homyk ,  Victor Marcel Acosta ,  Vikram Singh Bajaj

    IPC: A61K49/00 ,  A61B5/00 ,  A61B5/1455

    CPC classification number: G01N33/54333 ,  A61B5/0022 ,  A61B5/0051 ,  A61B5/0093 ,  A61B5/0095 ,  A61B5/05 ,  A61B5/0515 ,  A61B5/055 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/14558 ,  A61B5/1468 ,  A61B5/681 ,  A61B5/7435 ,  A61B8/4227 ,  A61B8/481 ,  A61K49/0017 ,  A61K49/0067 ,  A61K49/0093 ,  A61K49/1827 ,  B82Y15/00 ,  B82Y30/00 ,  G01N21/00 ,  G01N33/54346 ,  G01N33/54366 ,  G01N33/588 ,  G01R33/5601

    Abstract: An engineered particle for detecting analytes in an environment includes an electromagnetic receiver that is configured to preferentially receive electromagnetic radiation of a specified polarization relative to the orientation of the electromagnetic receiver. The engineered particle additionally includes an energy emitter coupled to the electromagnetic receiver such that a portion of electromagnetic energy received by the electromagnetic receiver is transferred to and emitted by the energy emitter. The engineered particles are functionalized to selectively interact with an analyte. The engineered particle can additionally be configured to align with a directed energy field in the environment. The selective reception of electromagnetic radiation of a specified polarization and/or alignment with a directed energy field can enable orientation tracking of individual engineered particles, imaging in high-noise environments, or other applications. A method for detecting properties of the analyte of interest by interacting with the engineered particle is also provided.

    Abstract translation: 用于检测环境中的分析物的工程颗粒包括电磁接收器，其被配置为优先接收相对于电磁接收器的取向的指定极化的电磁辐射。 工程颗粒另外包括耦合到电磁接收器的能量发射器，使得由电磁接收器接收的电磁能量的一部分被转移到能量发射器并由能量发射器发射。 工程化的颗粒被功能化以选择性地与分析物相互作用。 工程颗粒还可以被配置为与环境中的定向能量场对准。 选择性地接收具有定向能量场的指定极化和/或对准的电磁辐射可以实现各个工程化颗粒的取向跟踪，在高噪声环境中的成像或其它应用。 还提供了通过与工程化颗粒相互作用来检测目标分析物的性质的方法。

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