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公开(公告)号：US20210338414A1
公开(公告)日：2021-11-04
申请号：US17243858
申请日：2021-04-29
Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Inventor： Chih-Chieh HUANG , Jeng-Liang KUO , Hui-Ting HUANG , Shiun-Yin CHANG , Meng-Hsueh LIN , Cheng-Yi WU , Lih-Tao HSU , Pei-I TSAI , Hsin-Hsin SHEN , Chih-Yu CHEN , Kuo-Yi YANG , Chun-Hsien MA
IPC: A61F2/08
Abstract: A tissue repair device and a method for using the same are provided. The tissue repair device includes a body portion and at least one wire. The body portion includes an inner layer and an outer layer. The inner layer is close to a tissue, wherein the inner layer includes a hydrophilic structure, and the outer layer includes a hydrophobic structure. The wire is connected to the body portion to fix the body portion to the tissue.
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公开(公告)号：US20170172686A1
公开(公告)日：2017-06-22
申请号：US15211141
申请日：2016-07-15
Inventor： Yu-Bing LIOU , Hsiu-Ying WANG , Hsin-Yi HSU , Wei-Li CHEN , Chin-Tsung HUANG , Hsin-Hsin SHEN
CPC classification number: A61B90/04 , A61B2090/0427 , A61B2090/0445 , A61B2090/0472 , A61B2090/08021 , A61F9/00745 , A61L27/16 , A61L27/18 , A61L27/24 , A61L31/044 , A61L31/048 , A61L31/06 , A61L31/129 , A61L2430/16 , C08L71/02 , C08L39/06
Abstract: According to embodiments, a membrane with a flat or curved surface is provided for protection of intraocular tissues. The membrane can be used to cover the cornea for protecting corneal endothelial cells, to cover the anterior and posterior surface of the iris, or to cover the surface of the posterior capsule for separating the intraocular tissues. The membrane has a layered structure, which is composed of a collagen and a hydrophilic biopolymer or an organic polymer material. In particular, the membrane has high transparency and high water retention in a wet state.
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公开(公告)号：US20230172720A1
公开(公告)日：2023-06-08
申请号：US17550889
申请日：2021-12-14
Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Inventor： Fang-Chieh CHANG , Pei-I TSAI , Shih-Ping LIN , Ming-Jun LI , Chih-Chieh HUANG , Hsin-Hsin SHEN , Meng-Huang WU
CPC classification number: A61F2/4425 , A61F2/30771 , A61F2002/443 , A61F2002/30599 , A61F2002/30326 , A61F2002/30784 , A61F2002/30354
Abstract: An artificial intervertebral disc is configured to be inserted between adjacent human vertebrae. The artificial intervertebral disc includes a first connection block, a joint block and a second connection block. The joint block has a convex surface and a rear surface. The rear surface of the joint block is stacked on the first connection block. The second connection block is slidably stacked on the convex surface of the joint block, such that the second connection block is movable relative to the first connection block. In addition, the convex surface is a curved surface, and the convex surface is arranged off-axis with respect to the rear surface.
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公开(公告)号：US20220169808A1
公开(公告)日：2022-06-02
申请号：US17537728
申请日：2021-11-30
Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Inventor： Wei-Hong CHANG , Ching-Mei CHEN , Grace H. CHEN , Hsin-Hsin SHEN , Yuchi WANG , Ming-Chia YANG , Li-Hsin LIN , Sen-Lu CHEN , Yi-Hsuan LEE , Jian-Wei LIN , Liang-Cheng SU
Abstract: An anti-curling film is provided. The anti-curling film includes a first portion and a second portion covering the first portion. The first portion includes polylactic acid (PLA), polycaprolactone (PCL), polyethylene glycol dimethacrylate (PEGDMA) and a photoinitiator. The second portion includes polycaprolactone (PCL), gelatin, hyaluronic acid (HA), alginate (AA), polyvinyl alcohol (PVA) or a combination thereof.
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公开(公告)号：US20210340693A1
公开(公告)日：2021-11-04
申请号：US17244742
申请日：2021-04-29
Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Inventor： Shinn-Jen CHANG , Wesley Jen-Yang CHANG , Hsin-Hsin SHEN , Pei-Yi TSAI
Abstract: A method of preparing fiber includes blending bio-compatible ceramic powder and first polyester to form a ceramic powder composition, wherein the bio-compatible ceramic powder and the first polyester have a weight ratio of 10:90 to 60:40. The method further includes blending the ceramic powder composition and second polyester to form a composite material, wherein the ceramic powder composition and the second polyester have a weight ratio of 0.4:99.6 to 40:60. The method also spins the composite material to form a fiber. The first polyester has an intrinsic viscosity (IV) of 0.35 dL/g to 0.55 dL/g, and the second polyester has an intrinsic viscosity (IV) of 0.6 dL/g to 0.8 g/dL. The fiber can be woven to form an artificial ligament/tendon.
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Patent Agency Ranking
公开(公告)号：US20170106125A1
公开(公告)日：2017-04-20
申请号：US15294047
申请日：2016-10-14
Applicant: Industrial Technology Research Institute
Inventor： Yu-Chi WANG , Hsin-Hsin SHEN , Chin-Fu CHEN , Meng-Yow HSIEH , Sen-Lu CHEN , Yu-Bing LIOU , Tsai-Yu LIN , Pei-Shan LI , Wei-Lin YU
CPC classification number: A61L31/145 , A61L31/041 , A61L31/048 , A61L31/14 , A61L2400/06 , C08L29/04
Abstract: The present disclosure provides a hydrogel composition including: a hydrogel having a structure represented by Formula (I) or Formula (II) shown as follows: A-B-BOX-B-A, Formula (I); B-A-B-(BOX-BAB)n-BOX-B-A-B, Formula (II), wherein, A is a hydrophilic polyethylene glycol polymer, B is a hydrophobic polyester polymer, BOX is a bifunctional group monomer of 2,2′-Bis(2-oxazoline) for coupling di-block of A-B or tri-block of B-A-B, and n is an integer greater than or equal to 0; and an anti-adhesion additive, wherein the anti-adhesion additive comprises a carbohydrate, a nitrogen-containing cyclic compound, a polymer or a combination thereof.
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公开(公告)号：US20140161842A1
公开(公告)日：2014-06-12
申请号：US13870178
申请日：2013-04-25
Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Inventor： Li-Hsin LIN , Hsin-Hsin SHEN , Ying-Hsueh CHAO , Hsiu-Hua HUANG , Yu-Bing LIOU , Chih-Bing HUNG , Chin-Fu CHEN
CPC classification number: A61L27/26 , A61K9/006 , A61K9/70 , A61K9/7007 , A61L27/54 , A61L27/56 , A61L27/58 , C08L67/04 , C08L71/02
Abstract: A bioresorbable porous film, including a blend mixture of polylactic acid and at least two kinds of polyethylene glycol, wherein the at least two kinds of polyethylene glycol include a first polyethylene glycol, which is in a solid form under ambient temperature and atmospheric pressure, and a second polyethylene glycol, which is in a liquid form under ambient temperature and atmospheric pressure is provided. The film has a porosity of 10%-90%.
Abstract translation: 一种生物可吸收多孔膜，其包括聚乳酸和至少两种聚乙二醇的混合物，其中所述至少两种聚乙二醇包括在环境温度和大气压下为固体形式的第一聚乙二醇，以及 提供在环境温度和大气压下为液体形式的第二聚乙二醇。 该膜的孔隙率为10％-90％。
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公开(公告)号：US20220388293A1
公开(公告)日：2022-12-08
申请号：US17885874
申请日：2022-08-11
Applicant: Industrial Technology Research Institute
Inventor： Hsin-Hsin SHEN , Yu-Chi WANG , Ming-Chia YANG , Yu-Bing LIOU , Wei-Hong CHANG , Yun-Han LIN , Hsin-Yi HSU , Yun-Chung TENG , Chia-Jung LU , Yi-Hsuan LEE , Jian-Wei LIN , Kun-Mao KUO , Ching-Mei CHEN
Abstract: A method for preparing a bifunctional film, including: (a) drying a first polymer solution to form a film to form an anti-adhesion layer, and (b) drying a second polymer solution over the anti-adhesion layer to form a film to form an attachment layer. The first polymer solution includes a first hydrophobic solution and a first hydrophilic solution, and in the first polymer solution, the weight ratio of the solute of the first hydrophobic solution to the solute of the first hydrophilic solution is 1:0.01-1. Moreover, the second polymer solution is composed of a second hydrophilic solution.
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公开(公告)号：US20220204936A1
公开(公告)日：2022-06-30
申请号：US17475794
申请日：2021-09-15
Applicant: Industrial Technology Research Institute
Inventor： Yu-Bing LIOU , Chih-Ching LIAO , Hsin-Yi HSU , Ying-Wen SHEN , Yun-Chung TENG , Hsin-Hsin SHEN , Yi-Chen CHEN
Abstract: A non-fibrous film of which the composition includes a collagen and a polyester polymer is provided. A content of the polyester polymer in the non-fibrous film is 1-60 wt %. Moreover, the non-fibrous film has a swelling rate of 1-200 μm/hour or a swelling proportion per unit time of 0.1-2%/hour in an aqueous liquid.
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公开(公告)号：US20210137699A1
公开(公告)日：2021-05-13
申请号：US16725481
申请日：2019-12-23
Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Inventor： Fang-Jie JANG , Pei-I TSAI , Chih-Chieh HUANG , De-Yau LIN , Wei-Lun FAN , Yi-Hung WEN , Kuo-Yi YANG , Hsin-Hsin SHEN
Abstract: The disclosure relates to a spinal intervertebral body fusion device including an adjustable spacer, a first and second pushing piece, and an operative piece. The adjustable spacer includes a first and second supporting plate. The first supporting plate portion is movably installed on the second supporting plate portion. The first and second supporting plate portions form a first and second opening respectively located at two opposite sides of the adjustable spacer. The first pushing piece located at the first opening and is partially clamped by the first and second supporting plate portions. The second pushing piece located at the second opening is partially clamped by the first and second supporting plate portions. The operative piece is movably disposed through the second pushing piece and screwed to the first pushing piece. The operative piece has an annular slot, and the second pushing piece is partially located in the annular slot.
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