公开(公告)号：US10597707B2

公开(公告)日：2020-03-24

申请号：US14727442

申请日：2015-06-01

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Christina Bormann Chung ,  Julio Mulero ,  Lori Hennessy

IPC: C12Q1/68 ,  C12Q1/6858 ,  C12Q1/6888 ,  C12Q1/6879 ,  C12Q1/686

Abstract: Novel Y-STR multiplex analysis designs, primer design, allelic ladders, methods of use and kits are disclosed, including the use of primer sets designed to provide amplicons for at least 11 Y-STR loci having a base pair size of less than about 220 bp, as well as the use of primer sets designed to provide amplicons for at least 22 Y-STR loci including at least 5 rapidly mutating loci.

公开(公告)号：US20160053311A1

公开(公告)日：2016-02-25

申请号：US14727442

申请日：2015-06-01

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Christina BORMANN CHUNG ,  Julio Mulero ,  Lori Hennessy

IPC: C12Q1/68

CPC classification number: C12Q1/6858 ,  C12Q1/686 ,  C12Q1/6879 ,  C12Q1/6888 ,  C12Q2600/156 ,  C12Q2600/16 ,  C12Q2525/101 ,  C12Q2525/204 ,  C12Q2537/143

Abstract: Novel Y-STR multiplex analysis designs, primer design, allelic ladders, methods of use and kits are disclosed, including the use of primer sets designed to provide amplicons for at least 11 Y-STR loci having a base pair size of less than about 220 bp, as well as the use of primer sets designed to provide amplicons for at least 22 Y-STR loci including at least 5 rapidly mutating loci.

Abstract translation: 公开了新颖的Y-STR多重分析设计，引物设计，等位基因梯度，使用方法和试剂盒，包括使用设计用于提供具有小于约220的碱基对大小的至少11个Y-STR基因座的扩增子的引物组 bp，以及设计用于为包含至少5个快速突变基因座的至少22个Y-STR基因座提供扩增子的引物组的使用。

公开(公告)号：US09057110B2

公开(公告)日：2015-06-16

申请号：US13914478

申请日：2013-06-10

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Chien-Wei Chang ,  Lori Hennessy ,  Dennis Wang

IPC: C12Q1/68

CPC classification number: C12Q1/6888 ,  C12Q1/68 ,  C12Q1/6806 ,  C12Q1/686 ,  C12Q2527/125

Abstract: The present teachings relate to improved methods, kits, and reaction mixtures for amplifying nucleic acids. In some embodiments a novel direct buffer formulation is provided which allows for the direct amplification of the nucleic acids in a crude sample with minimal sample purification.

Abstract translation: 本教导涉及用于扩增核酸的改进的方法，试剂盒和反应混合物。 在一些实施方案中，提供了新的直接缓冲液制剂，其允许以最少的样品纯化直接扩增粗样品中的核酸。

公开(公告)号：US09804066B2

公开(公告)日：2017-10-31

申请号：US14739899

申请日：2015-06-15

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Michael Harrold ,  Lori Hennessy ,  Jason Yingjie Liu ,  Chang Zhong

IPC: C12Q1/68 ,  C12M1/00 ,  C12M1/34 ,  G01N1/30 ,  G06T7/00 ,  A61B5/15 ,  A61B5/151 ,  A61B5/00 ,  A61B5/1172 ,  A61B5/145 ,  G06K9/00 ,  A61B10/00 ,  A61B10/02 ,  A61B5/157

CPC classification number: G01N1/30 ,  A61B5/0077 ,  A61B5/1172 ,  A61B5/1411 ,  A61B5/14514 ,  A61B5/150022 ,  A61B5/150083 ,  A61B5/150091 ,  A61B5/150412 ,  A61B5/150984 ,  A61B5/15105 ,  A61B5/15134 ,  A61B5/157 ,  A61B10/0064 ,  A61B10/0233 ,  G06K9/00013 ,  G06K9/00543 ,  G06K2009/00946 ,  G06T7/0012

Abstract: Systems, methods, and kits are disclosed for collection, labeling and analyzing biological samples containing nucleic acid in conjunction with collecting at least one ridge and valley signature of an individual. Such devices and methods are used in forensic, human identification, access control and screening technologies to rapidly process an individual's identity or determine the identity of an individual.

公开(公告)号：US09518302B2

公开(公告)日：2016-12-13

申请号：US14739722

申请日：2015-06-15

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Chien-Wei Chang ,  Lori Hennessy ,  Dennis Wang

IPC: C12P19/34 ,  C12Q1/68

CPC classification number: C12Q1/6888 ,  C12Q1/68 ,  C12Q1/6806 ,  C12Q1/686 ,  C12Q2527/125

Abstract: The present teachings relate to improved methods, kits, and reaction mixtures for amplifying nucleic acids. In some embodiments a novel direct buffer formulation is provided which allows for the direct amplification of the nucleic acids in a crude sample with minimal sample purification.

公开(公告)号：US20150031031A1

公开(公告)日：2015-01-29

申请号：US14380513

申请日：2013-02-22

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Michael Harrold ,  Lori Hennessy ,  Leonard Klevan

IPC: C12Q1/68 ,  A61B10/02 ,  A61B5/117 ,  G06F17/30 ,  G06K9/00

CPC classification number: G16H10/40 ,  A61B5/1172 ,  A61B5/1174 ,  A61B10/0045 ,  A61B10/0051 ,  A61B10/02 ,  C12Q1/6806 ,  C12Q1/6881 ,  G06F16/245 ,  G06F19/321 ,  G06K9/00013 ,  G16H10/60 ,  G16H30/20

Abstract: Disclosed are devices and methods for collection, labeling and matching biological samples containing nucleic acid in conjunction with collecting at least one ridge and valley signature such as a fingerprint or footprint of an individual. Such devices and methods are used in forensic, human identification, paternity, tissue typing, and screening technologies to rapidly process an individual's identity, determine the identity of an individual along with the genotype profile of the individual.

Abstract translation: 公开了用于收集，标记和匹配含有核酸的生物样品与收集至少一个山脊和山谷特征如个体的指纹或足迹的装置和方法。 这些装置和方法用于法医，人类鉴别，亲子鉴定，组织分型和筛选技术，以快速处理个体的身份，确定个体的身份以及个体的基因型。

公开(公告)号：US20140120541A1

公开(公告)日：2014-05-01

申请号：US13914478

申请日：2013-06-10

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Chien-Wei CHANG ,  Lori Hennessy ,  Dennis Wang

IPC: C12Q1/68

CPC classification number: C12Q1/6888 ,  C12Q1/68 ,  C12Q1/6806 ,  C12Q1/686 ,  C12Q2527/125

Abstract: The present teachings relate to improved methods, kits, and reaction mixtures for amplifying nucleic acids. In some embodiments a novel direct buffer formulation is provided which allows for the direct amplification of the nucleic acids in a crude sample with minimal sample purification.

Abstract translation: 本教导涉及用于扩增核酸的改进的方法，试剂盒和反应混合物。 在一些实施方案中，提供了新的直接缓冲液制剂，其允许以最少的样品纯化直接扩增粗样品中的核酸。

公开(公告)号：US11207004B2

公开(公告)日：2021-12-28

申请号：US16454886

申请日：2019-06-27

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Michael Harrold ,  Lori Hennessy ,  Leonard Klevan

IPC: A61B5/1172 ,  G16H10/60 ,  G06F16/245 ,  A61B10/00 ,  A61B5/1174 ,  A61B10/02 ,  C12Q1/6806 ,  G06K9/00 ,  C12Q1/6881 ,  G16H10/40 ,  G16H40/63 ,  G16H30/20

Abstract: Disclosed are devices and methods for collection, labeling and matching biological samples containing nucleic acid in conjunction with collecting at least one ridge and valley signature such as a fingerprint or footprint of an individual. Such devices and methods are used in forensic, human identification, paternity, tissue typing, and screening technologies to rapidly process an individual's identity, determine the identity of an individual along with the genotype profile of the individual.

公开(公告)号：US20160154990A1

公开(公告)日：2016-06-02

申请号：US14865079

申请日：2015-09-25

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Michael Harrold ,  Lori Hennessy ,  Robert Lagace

IPC: G06K9/00

CPC classification number: G06K9/00013 ,  A61B5/1172 ,  A61B5/1174 ,  A61B5/1176 ,  A61B5/14546 ,  A61B5/150022 ,  A61B5/150099 ,  A61B5/150229 ,  A61B5/150267 ,  A61B5/150305 ,  A61B5/150396 ,  A61B5/150404 ,  A61B5/150419 ,  A61B5/150427 ,  A61B5/150435 ,  A61B5/150511 ,  A61B5/150748 ,  A61B5/150755 ,  A61B5/150786 ,  A61B5/150847 ,  A61B5/150954 ,  A61B5/15109 ,  A61B5/1519 ,  A61B5/157 ,  A61B10/0045 ,  A61B10/02 ,  G05B1/00 ,  G06K9/00006 ,  G06K9/0008 ,  G06K9/00107 ,  G06K9/00892 ,  G06K2209/07

Abstract: Disclosed are devices and methods for collection and analyzing biological samples containing nucleic acid in conjunction with collecting at least one ridge and valley signature of a test subject, while keeping the sample and signature associated with each other. Such devices and methods are used in forensic, human identification, screening, and access control technologies to rapidly process an individual's identity or determine the identity of an individual.

公开(公告)号：US12245854B2

公开(公告)日：2025-03-11

申请号：US17516969

申请日：2021-11-02

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Michael Harrold ,  Lori Hennessy ,  Leonard Klevan

IPC: A61B5/1172 ,  A61B5/1174 ,  A61B10/00 ,  A61B10/02 ,  C12Q1/6806 ,  C12Q1/6881 ,  G06F16/245 ,  G16H10/60 ,  G16H10/40 ,  G16H30/20 ,  G16H40/63

Abstract: Disclosed are devices and methods for collection, labeling and matching biological samples containing nucleic acid in conjunction with collecting at least one ridge and valley signature such as a fingerprint or footprint of an individual. Such devices and methods are used in forensic, human identification, paternity, tissue typing, and screening technologies to rapidly process an individual's identity, determine the identity of an individual along with the genotype profile of the individual.