Hyaluronic acid derivative gel and method for preparing the same
    1.
    发明申请
    Hyaluronic acid derivative gel and method for preparing the same 审中-公开
    透明质酸衍生物凝胶及其制备方法

    公开(公告)号:US20060166928A1

    公开(公告)日:2006-07-27

    申请号:US10521003

    申请日:2003-05-21

    IPC分类号: A61K31/728 C08B37/00

    摘要: The present invention relates to a hyaluronic acid derivative gel, obtained by amidation of a hyaluronic acid, or its cationic salt, and an amine group-containing saccharide compound, having excellent viscoelastic properties, and a method for preparing it. Especially, the hyaluronic acid derivative gel according to the present invention shows responses peculiar to heat and can be made to have various properties by heat treatment. The hyaluronic acid derivative gel according to the present invention can be used for a variety of purposes such as post-operative adhesion-preventing gel, material for wrinkle treatment, auxiliary material for plastic surgery, material for arthritis treatment, and drug delivery vehicle.

    摘要翻译: 本发明涉及透明质酸衍生物凝胶,其透明质酸衍生物凝胶,其透明质酸或其阳离子盐和具有优异粘弹性的胺基糖类化合物的酰胺化及其制备方法。 特别地,根据本发明的透明质酸衍生物凝胶显示出热特有的反应,并且可以通过热处理使其具有各种性质。 根据本发明的透明质酸衍生物凝胶可以用于各种目的,例如术后粘合防止凝胶,用于皱纹治疗的材料,用于整形手术的辅助材料,用于关节炎治疗的材料和药物递送载体。

    Laser induced thermal imaging apparatus and manufacturing method of organic light emitting diode using the same
    2.
    发明申请
    Laser induced thermal imaging apparatus and manufacturing method of organic light emitting diode using the same 有权
    激光感应热成像装置及使用其的有机发光二极管的制造方法

    公开(公告)号:US20070048657A1

    公开(公告)日:2007-03-01

    申请号:US11510372

    申请日:2006-08-24

    IPC分类号: G03C8/00

    摘要: A laser induced thermal imaging apparatus and a manufacturing method of organic light emitting diodes using the same, which reduce or prevent the occurrence of impurities or void between an acceptor substrate and a donor film while performing a laser induced thermal imaging in a vacuum state. A laser induced thermal imaging apparatus includes: a substrate stage including an acceptor substrate for receiving an imaging layer, the imaging layer being formed on the acceptor substrate, and an electromagnet, a donor film having a permanent magnet being placed and laminated on the substrate stage, and the electromagnet forming a magnetic force with a permanent magnet of the donor film; a laser oscillator for irradiating a laser to the donor film; and a chamber having at least the substrate stage located therein.

    摘要翻译: 激光感应热成像装置和使用其的有机发光二极管的制造方法,其在真空状态下执行激光诱导热成像的同时减少或防止受主基板和施主膜之间的杂质或空隙的发生。 激光诱导热成像装置包括:衬底台,包括用于接收成像层的受主衬底,成像层形成在受主衬底上,以及电磁体,具有永磁体的施主膜并层压在衬底台上 电磁体与施主膜的永久磁铁形成磁力; 激光振荡器,用于向施主膜照射激光; 以及至少具有位于其中的基板台的室。

    Process for the preparation of optically pure 4-hydroxy-2-oxo-1-pyrrolidine acetamide
    3.
    发明申请
    Process for the preparation of optically pure 4-hydroxy-2-oxo-1-pyrrolidine acetamide 审中-公开
    制备光学纯的4-羟基-2-氧代-1-吡咯烷乙酰胺的方法

    公开(公告)号:US20070185337A1

    公开(公告)日:2007-08-09

    申请号:US11596580

    申请日:2005-05-25

    IPC分类号: C07D207/04

    CPC分类号: C07D207/273

    摘要: A process for the preparation of chiral 4-hydroxy-2-oxo-1-pyrrolidine acetamide includes adding sodium cyanide together with citric acid to a solution of chiral epichlorohydrin to obtain chiral 3-chloro-2-hydroxypropionitrile by ring opening reaction of the chiral epichlorohydrin, reacting the obtained product with an alcohol containing hydrochloride gas to obtain chiral 4-chloro-3-hydroxybutyric acid ester, and reacting the obtained product in a presence of a base with glycinamide or with glycine ester accompanied by ammonolysis with ammonia to produce the targeted chiral 4-hydroxy-2-oxo-1-pyrrolidine acetamide.

    摘要翻译: 手性4-羟基-2-氧代-1-吡咯烷乙酰胺的制备方法包括将氰化钠与柠檬酸一起加入到手性表氯醇的溶液中,以通过手性的开环反应获得手性3-氯-2-羟基丙腈 将得到的产物与含有盐酸气体的醇反应,得到手性4-氯-3-羟基丁酸酯,并使得到的产物在碱的存在下与甘氨酰胺或甘氨酸酯反应,伴随着氨的氨解,生成 靶向手性4-羟基-2-氧代-1-吡咯烷乙酰胺。

    Laser induced thermal imaging apparatus and laser induced thermal imaging method
    4.
    发明申请
    Laser induced thermal imaging apparatus and laser induced thermal imaging method 有权
    激光诱导热成像设备和激光诱导热成像方法

    公开(公告)号:US20070046770A1

    公开(公告)日:2007-03-01

    申请号:US11509463

    申请日:2006-08-23

    IPC分类号: B41J2/45

    摘要: A laser induced thermal imaging apparatus and a laser induced thermal imaging method. A laser induced thermal imaging apparatus has electromagnets in an adhesion frame and a substrate stage to closely adhere a donor film to a substrate. The laser induced thermal imaging apparatus includes a process chamber including a donor film and a substrate, and adapted to carry out a process for depositing the donor film on the substrate; a substrate stage having a first electromagnet, and positioned in the process chamber to support the substrate; an adhesion frame having a second electromagnet, and positioned over the substrate stage, wherein the donor film and the substrate are disposed between the substrate stage and the adhesion frame in the process chamber; and a laser oscillator adapted to apply a laser output to the donor film.

    摘要翻译: 激光诱导热成像装置和激光诱导热成像方法。 激光感应热成像装置在粘合框架和基底台中具有电磁体,以将施主膜紧密地附着于基底。 所述激光诱导热成像装置包括:处理室,其包括施主膜和基板,并且适于执行将所述施主膜沉积在所述基板上的工艺; 具有第一电磁体的基板台,并且位于所述处理室中以支撑所述基板; 具有第二电磁体并且位于所述衬底台上的粘合框架,其中所述施主膜和所述衬底设置在所述处理室中的所述衬底台和所述粘合框架之间; 以及适于将激光输出施加到供体膜的激光振荡器。

    Method for encoding and decoding error correction block
    5.
    发明申请
    Method for encoding and decoding error correction block 审中-公开
    纠错块编码和解码方法

    公开(公告)号:US20060015801A1

    公开(公告)日:2006-01-19

    申请号:US11185851

    申请日:2005-07-21

    IPC分类号: G06F11/00 H03M13/00

    摘要: The present invention relates to a method for encoding and decoding an error correction block, and more particularly to a method for encoding and decoding an error correction block useful for a high-density optical disc. When an error correction block is encoded, a user data block is generated and parity outer information for a vertical data stream within the user data block is generated. Then, parity inner information is generated using an eraser detection code contained in a horizontal data stream or at least one of a syndrome check parity, a sync byte and an indicator flag is generated within the user data block so that an eraser can be declared in the horizontal data stream at a predetermined internal. On the other hand, when the error correction block is decoded, a determination is made as to whether errors are detected from the eraser detection code, the syndrome check parity, etc., and erasers are declared according to a result of the determination.

    摘要翻译: 本发明涉及一种用于对纠错块进行编码和解码的方法,更具体地说,涉及用于对高密度光盘有用的纠错块进行编码和解码的方法。 当对纠错块进行编码时,生成用户数据块,生成用户数据块内的垂直数据流的奇偶校验外部信息。 然后,使用包含在水平数据流中的橡皮擦检测码或者在用户数据块内生成校正子校验奇偶校验,同步字节和指示符标志中的至少一个来生成奇偶校验内部信息,从而可以将橡皮擦声明为 水平数据流在预定的内部。 另一方面,当解码错误块时,根据确定结果确定是否从橡皮擦检测码,检验奇偶校验等检测到错误,并确定擦除器。

    In-Gel Tagging And In-Gel Digestion For Phosphoproteins Analysis And Phosphorylation Site Identification
    6.
    发明申请
    In-Gel Tagging And In-Gel Digestion For Phosphoproteins Analysis And Phosphorylation Site Identification 失效
    凝胶标记和凝胶消化磷蛋白分析和磷酸化位点鉴定

    公开(公告)号:US20070287169A1

    公开(公告)日:2007-12-13

    申请号:US11574660

    申请日:2004-10-08

    IPC分类号: C12P21/06 C07K14/00

    CPC分类号: G01N33/6842 G01N33/6848

    摘要: The present invention relates to a method for phosphorylation site-specific labeling of phosphoproteome with a site-specific tagging reagent and analyzing of the resulting labeled one, more especially, a method for in-situ tagging of phosphorylation sites of phosphoproteins retained in polymeric gel with a nucleophilic tagging reagent. It also relates a method for generating new proteolytic cleavable sites at formerly phosphorylation sites by a proper choice of a nucleophilic tagging reagent. It also relates to a method for phosphopeptides analysis and phosphorylation site identification by in-gel digestion of the previously in-gel tagged proteins and subsequent mass analysis of the resulting peptides. The invention provides in-gel chemical tagging method for phosphoaminoacid residue of phosphoproteins retained in polymeric gel matrix. Phosphoprotein can be immobilized into gel matrix by a variety of methods such as gel electrophoresis. The immobilized phosphoproteins are retained in gel matrix during tagging reaction to phosphorylated aminoacid residue of phosphoproteins, and the resulting tagged proteins are also retained in gel matrix till following purification steps like washing of the tagging reagents are accomplished. The tagged proteins is digested by protease, and the resulting digested peptides is released from gel into solution and applied for peptide mass analysis.

    摘要翻译: 本发明涉及用位点特异性标记试剂对磷酸化蛋白质进行磷酸化位点特异性标记的方法,并分析得到的标记物,更具体地说,一种用于原位标记保留在聚合物凝胶中的磷酸化蛋白的磷酸化位点的方法, 亲核标记试剂。 它还涉及通过适当选择亲核标记试剂在以前的磷酸化位点产生新的蛋白水解可切割位点的方法。 它还涉及通过凝胶内消化先前凝胶内标记蛋白的磷酸肽分析和磷酸化位点鉴定的方法以及随后对所得肽的质量分析。 本发明提供了凝胶化学标记方法,用于保留在聚合物凝胶基质中的磷酸蛋白的磷酸氨基酸残基。 磷酸蛋白可以通过各种方法如凝胶电泳固定在凝胶基质中。 在磷酸化蛋白质的磷酸化氨基酸残基的标签反应期间,将固定的磷酸蛋白质保留在凝胶基质中,并且所得到的标记蛋白质也保留在凝胶基质中,直到完成标记试剂的洗涤之后的纯化步骤。 标记的蛋白质被蛋白酶消化,并将得到的消化肽从凝胶释放到溶液中并用于肽质量分析。

    Method for producing polymeric sol of calcium phosphate compound and method for coating the same on a metal implant
    7.
    发明申请
    Method for producing polymeric sol of calcium phosphate compound and method for coating the same on a metal implant 有权
    磷酸钙化合物的聚合物溶胶的制造方法及其在金属植入物上的涂布方法

    公开(公告)号:US20050158399A1

    公开(公告)日:2005-07-21

    申请号:US10809509

    申请日:2004-03-26

    摘要: Disclosed is a method for producing a transparent and homogenized polymeric sol of a calcium phosphate compound, containing apatite and having excellent wettability and bioactivity, according to a sol-gel synthesis, and a method for coating the polymeric sol on a metal implant, in which the polymeric sol is coated on the metal implant and then heat-treated to form a dense coated layer strongly bonded to the metal implant. The polymeric sol is obtained by process of preparing a calcium salt solution, containing calcium ethoxide dissolved in organic acid, and a phosphate solution, containing triethyl phosphite or triethyl phosphate dissolved in the organic acid, mixing the calcium salt solution with the phosphate solution to produce a mixed solution, and aging the mixed solution.

    摘要翻译: 本发明公开了一种根据溶胶 - 凝胶合成法生产含有磷灰石并具有优异的润湿性和生物活性的磷酸钙化合物的透明均化聚合物溶胶的方法,以及在金属植入物上涂覆聚合物溶胶的方法,其中 将聚合物溶胶涂覆在金属植入物上,然后进行热处理以形成与金属植入物牢固结合的致密涂层。 通过制备溶解在有机酸中的含有乙醇钙的钙盐溶液和溶解在有机酸中的含有亚磷酸三乙酯或磷酸三乙酯的磷酸盐溶液,将钙盐溶液与磷酸盐溶液混合,得到聚合物溶胶 混合溶液,老化混合溶液。

    Refrigerator
    8.
    发明申请
    Refrigerator 审中-公开
    冰箱

    公开(公告)号:US20060070395A1

    公开(公告)日:2006-04-06

    申请号:US11143458

    申请日:2005-06-03

    申请人: Jae Lee Jae Lee June Min

    发明人: Jae Lee Jae Lee June Min

    IPC分类号: F25D17/04 F25D17/06

    摘要: A refrigerator capable of adjusting a discharge position and a quantity of cold air discharged into the refrigerator. The refrigerator includes an inner panel installed at a rear surface of a storage chamber and having cold air outlets for forming a cooling channel. The refrigerator also includes a variable duct installed at one of the cold air outlets such that the variable duct can move back and forth to vary a length of the cooling channel, and a plurality of cold air distribution holes formed in the variable duct.

    摘要翻译: 一种能够调节排出位置的冰箱以及排入冰箱的冷气的量。 冰箱包括安装在存储室的后表面的内板,并具有用于形成冷却通道的冷气出口。 冰箱还包括安装在一个冷气出口处的可变管道,使得可变管道可前后移动以改变冷却通道的长度,以及形成在可变管道中的多个冷气分配孔。