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91.发明授权公开(公告)号：US09649163B2
公开(公告)日：2017-05-16
申请号：US13884407
申请日：2011-11-10
申请人： Ian J. Darisse , Arnold E. Oyola , Joseph A. Stand , Robert A. DiDomenico , Samuel F. Straface , J. Christopher Flaherty
发明人： Ian J. Darisse , Arnold E. Oyola , Joseph A. Stand , Robert A. DiDomenico , Samuel F. Straface , J. Christopher Flaherty
IPC分类号： A61B1/04 , A61B19/00 , A61B1/00 , A61B1/005 , A61B17/00 , A61B17/34 , A61B34/00 , A61B90/00 , A61B34/30
CPC分类号： A61B34/30 , A61B1/0011 , A61B1/00154 , A61B1/0016 , A61B1/0053 , A61B1/0055 , A61B1/0057 , A61B34/76 , A61B2017/00314 , A61B2017/3445 , A61B2034/301 , A61B2034/715 , A61B2034/742 , A61B2090/064 , A61B2090/3614
摘要： In an introduction assembly for an articulated probe, a feeding mechanism has actuators for controlling the articulated probe. The introduction device is fixed in a positional relationship to the feeding mechanism. The introduction device includes a support member configured to support an articulated probe. A proximal end of the support member has an entrance configured to guide the articulated probe into contact with the support member. A distal end of the support member has an exit configured to guide the articulated probe from the support member into a region of interest.
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公开(公告)号：US09622849B2
公开(公告)日：2017-04-18
申请号：US13502759
申请日：2010-10-28
申请人： Mohammed El-Kurdi , J. Christopher Flaherty , Yi Hong , Jonathan McGrath , Lorenzo Soletti , John Stankus , David Vorp , William Wagner
发明人： Mohammed El-Kurdi , J. Christopher Flaherty , Yi Hong , Jonathan McGrath , Lorenzo Soletti , John Stankus , David Vorp , William Wagner
CPC分类号： A61F2/06 , A61F2/04 , A61F2/062 , A61F2002/072
摘要： A tubular tissue graft device is provided comprising a tubular member and a restrictive fiber matrix of a bioerodible polymer about a circumference of the tubular tissue. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. 5 Also provided is method of preparing a tubular graft comprising depositing a fiber matrix of a bioerodible polymer about a perimeter of a tubular tissue to produce a tubular tissue graft device. A cardiac bypass method comprising bypassing a coronary artery with a tubular tissue graft device comprising a vein and a restrictive fiber matrix of a bioerodible polymer about a circumference of the vein also is provided.
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公开(公告)号：US09579224B2
公开(公告)日：2017-02-28
申请号：US14234974
申请日：2012-07-24
CPC分类号： A61F2/82 , A61B17/00008 , A61B17/11 , A61B17/135 , A61B2017/00778 , A61B2017/00969 , A61B2017/1107 , A61B2017/1132 , A61B2017/22097 , A61L27/3625 , A61L27/3687 , A61L27/3691 , A61L27/507
摘要： Methods and devices for treating a vessel for use in a medical procedure are disclosed. A vein or other vessel can be modified in situ, prior to harvesting. Subsequently, at least a portion of the vessel is removed, and subsequently implanted to treat a patient, typically in a bypass procedure in which the vessel portion fluidly connects a source of oxygenated blood to an occluded artery.
摘要翻译： 公开了用于治疗用于医疗过程的血管的方法和装置。 在收获之前，静脉或其他血管可以在原位进行修改。 随后，移除血管的至少一部分，随后植入以治疗患者，通常在旁路过程中，血管部分将氧合血液源流体连接到闭塞动脉。
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公开(公告)号：US09445874B2
公开(公告)日：2016-09-20
申请号：US13811206
申请日：2011-07-19
申请人： Lorenzo Soletti , Mohammed S. El-Kurdi , Jon McGrath , Andrew Ziegler , J. Christopher Flaherty , William R. Wagner , David Vorp
发明人： Lorenzo Soletti , Mohammed S. El-Kurdi , Jon McGrath , Andrew Ziegler , J. Christopher Flaherty , William R. Wagner , David Vorp
CPC分类号： B05B5/12 , A61B90/00 , A61F2/022 , A61F2/04 , A61F2/06 , A61F2/07 , A61F2002/043 , A61F2002/046 , A61F2002/047 , A61F2002/048 , A61F2240/001 , A61L27/3625 , B05B5/0255 , D01D5/0084 , D01D13/02
摘要： A cartridge device is provided for applying a fiber matrix to a tubular member such as a saphenous vein graft. The cartridge includes a housing, a tubular member holder, a rotational drive, and a polymer delivery assembly. The housing defines a chamber which surrounds the tubular member holder. The rotational drive rotates the tubular member during the fiber application process.
摘要翻译： 提供了用于将纤维基质施加到诸如隐静脉移植物的管状构件上的药筒装置。 盒包括壳体，管状构件保持器，旋转驱动器和聚合物输送组件。 壳体限定围绕管状构件保持器的腔室。 旋转驱动器在纤维施加过程中旋转管状构件。
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95.发明申请公开(公告)号：US20160262840A1
公开(公告)日：2016-09-15
申请号：US15064043
申请日：2016-03-08
申请人： Brett Zubiate , Arnold Oyola , Dale Whipple , Joseph A. Stand , Robert Didomenico , William H. Kennefick , J. Christopher Flaherty
发明人： Brett Zubiate , Arnold Oyola , Dale Whipple , Joseph A. Stand , Robert Didomenico , William H. Kennefick , J. Christopher Flaherty
CPC分类号： B25J9/065 , A61B1/0056 , A61B1/008 , A61B34/30 , B25J18/06
摘要： An articulating probe, comprises a first mechanism including a first link comprising a first longitudinal axis, a first articulation surface and a first motion-limiting element; and a second link comprising a second longitudinal axis, a second articulation surface and a second motion-limiting element. An articulation joint comprises the first articulation surface and the second articulation surface and constructed and arranged to allow two degree-of-freedom articulation of the second link relative to the first link. A motion resisting assembly comprises the first motion limiting element and the second motion limiting element, wherein the motion resisting assembly is constructed and arranged to resist rotation of the second link about the second longitudinal axis relative to the first longitudinal axis of the first link.
摘要翻译： 一种关节式探针，包括第一机构，其包括第一连杆，所述第一连杆包括第一纵向轴线，第一铰接表面和第一运动限制元件; 以及包括第二纵向轴线，第二铰接表面和第二运动限制元件的第二连杆。 铰接接头包括第一铰接表面和第二铰接表面，并且被构造和布置成允许第二连杆相对于第一连杆的两个自由度的铰接。 运动阻力组件包括第一运动限制元件和第二运动限制元件，其中运动阻力组件被构造和布置成抵抗第二连杆围绕第一纵向轴线相对于第一连杆的第一纵向轴线的旋转。
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公开(公告)号：US20160003761A1
公开(公告)日：2016-01-07
申请号：US14343376
申请日：2012-09-06
申请人： William CLARK , Sung Kwon CHO , Yuejun ZHAO , Timothy J. SYCIARZ , R. Maxwell Flaherty , J. Christopher Flaherty , David W. Wagner
发明人： William CLARK , Sung Kwon CHO , Yuejun ZHAO , Timothy J. SYCIARZ , R. Maxwell Flaherty , J. Christopher Flaherty , David W. Wagner
IPC分类号： G01N27/30
CPC分类号： G01N27/302 , B01L3/502738 , B01L2200/027 , B01L2200/0673 , B01L2300/0645 , B01L2300/0816 , B01L2300/0829 , B01L2300/087 , B01L2300/1827 , B01L2400/0406 , B01L2400/0427 , B01L2400/049 , B01L2400/0677 , G01N27/28 , G01N27/307 , G01N27/4035 , G01N33/4836
摘要： A system for obtaining a pH measurement includes a disposable probe and a reader. The disposable probe comprises multiple indicating electrodes and at least one reference electrode. The reader is configured to operably engage with the disposable probe and provide pH information of a sample.
摘要翻译： 用于获得pH测量的系统包括一次性探针和读取器。 一次性探针包括多个指示电极和至少一个参考电极。 读取器构造成可操作地与一次性探针接合并提供样品的pH信息。
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公开(公告)号：US09155572B2
公开(公告)日：2015-10-13
申请号：US13413550
申请日：2012-03-06
IPC分类号： A61B17/062 , A61B17/70 , A61B17/16 , A61B17/17 , A61B17/34 , A61B17/88 , A61B17/02 , A61B17/84 , A61B17/00 , A61B19/00 , A61F2/00
CPC分类号： A61B17/7065 , A61B17/0206 , A61B17/025 , A61B17/1671 , A61B17/1697 , A61B17/1757 , A61B17/3421 , A61B17/7062 , A61B17/7067 , A61B17/848 , A61B17/8866 , A61B17/8897 , A61B2017/00004 , A61B2017/0023 , A61B2017/00261 , A61B2017/00557 , A61B2017/0256 , A61B2090/033 , A61B2090/034 , A61B2090/062 , A61F2/0077
摘要： A plurality of individual tools is provided where each tool is uniquely configured to perform a step or a portion of a step in a novel procedure associated with the implantation of a stabilizing device (e.g., an interspinous spacer) for stabilizing at least one spinal motion segment. The tools are usable individually, or more preferably as a tooling system in which the tools are collectively employed to implant an interspinous spacer, generally in a minimally invasive manner. For example, each of the tools is arranged with coordinated markings and/or other features to ensure consistent depths of insertion, proper orientation of the tools with respect to each other or an anatomical feature of the patient, and precise delivery of the spacer to maintain safe positioning throughout the implantation procedure.
摘要翻译： 提供了多个单独的工具，其中每个工具被独特地构造成执行与植入稳定装置（例如，椎间间隔垫）相关联的新颖程序中的步骤或步骤的一部分，用于稳定至少一个脊柱运动段 。 工具可以单独使用，或更优选地用作工具系统，其中工具被集体用于植入椎间间隔垫，通常以微创方式。 例如，每个工具被布置成具有协调的标记和/或其他特征，以确保插入的一致深度，工具相对于彼此的适当取向或患者的解剖特征，以及间隔物的精确传递以维持 整个植入过程中的安全定位。
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98.发明授权Method of treating COPD with artificial arterio-venous fistula and flow mediating systems 有权用人造动静脉瘘和流媒体系统治疗COPD的方法公开(公告)号：US09011362B2
公开(公告)日：2015-04-21
申请号：US13529364
申请日：2012-06-21
CPC分类号： A61M27/006 , A61B17/11 , A61B17/12 , A61B17/12036 , A61B17/1204 , A61B17/12136 , A61B17/135 , A61B2017/00243 , A61B2017/00876 , A61B2017/1107 , A61B2017/1135 , A61B2017/1139 , A61M1/3653 , A61M1/3655 , A61M39/0208 , A61M39/28 , A61M2025/1052 , A61M2205/04 , A61M2205/3515 , A61M2210/12 , A61M2210/127 , A61M2230/005 , A61M2230/202 , A61M2230/205 , A61M2230/46
摘要： A method for treatment of COPD, hypertension, and left ventricular hypertrophy, and chronic hypoxia including creation of an artificial arterio-venous fistula and installation of a flow mediating device proximate the fistula. The flow mediating device is operated to limit flow as medically indicated to provide the optimum amount of bypass flow.
摘要翻译： 一种治疗COPD，高血压和左心室肥大的方法，以及慢性缺氧，包括造成人造动静脉瘘，并在瘘管附近安装流量调节装置。 流动介质装置被操作以限制流动，如医疗指示的，以提供最佳量的旁路流量。
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99.发明授权Systems for performing gynecological procedures with simultaneous tissue cutting and removal 有权执行妇科手术同时进行组织切割和移除的系统公开(公告)号：US08840626B2
公开(公告)日：2014-09-23
申请号：US11852200
申请日：2007-09-07
申请人： Ronald D. Adams , William H. Gruber , Kevin G. Connors , Geoffrey B. Pardo , James Daniel Cole , J. Christopher Flaherty
发明人： Ronald D. Adams , William H. Gruber , Kevin G. Connors , Geoffrey B. Pardo , James Daniel Cole , J. Christopher Flaherty
IPC分类号： A61B17/42 , A61B17/12 , A61B19/00 , A61B18/22 , A61B17/00 , A61B17/32 , A61B18/02 , A61B17/02 , A61B18/14
CPC分类号： A61B17/42 , A61B17/0218 , A61B17/12045 , A61B17/12099 , A61B17/12136 , A61B17/32002 , A61B18/02 , A61B18/1485 , A61B18/22 , A61B90/02 , A61B2017/00026 , A61B2017/00867 , A61B2017/320024 , A61B2017/320028 , A61B2017/4216 , A61B2017/4225 , A61B2017/4233 , A61B2090/3614 , A61B2090/378 , A61B2217/005 , A61B2217/007 , A61N5/1016
摘要： Systems, methods, apparatus and devices for performing improved gynecologic and urologic procedures are disclosed. The system is configured to permit simultaneous tissue cutting and removal from a target site. The various embodiments enable procedures to be performed outside the hospital setting, such as in a doctor's office or clinic.
摘要翻译： 公开了用于执行改进的妇科和泌尿系统程序的系统，方法，装置和装置。 该系统被配置为允许从目标部位同时进行组织切割和移除。 各种实施例使得在医院设置之外执行程序，例如在医生的办公室或诊所中。
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100.发明申请公开(公告)号：US20140228884A1
公开(公告)日：2014-08-14
申请号：US14154094
申请日：2014-01-13
IPC分类号： A61B17/70
CPC分类号： A61B17/7065 , A61B17/70 , A61B2017/00557
摘要： Devices, systems and methods for dynamically stabilizing the spine are provided. The devices include an expandable spacer having an undeployed configuration and a deployed configuration, wherein the spacer has axial and radial dimensions for positioning between the spinous processes of adjacent vertebrae. The systems include one or more spacers and a mechanical actuation means for delivering and deploying the spacer. The methods involve the implantation of one or more spacers within the interspinous space.
摘要翻译： 提供了用于动态稳定脊柱的装置，系统和方法。 这些装置包括具有未部署构造和展开构造的可扩展间隔件，其中间隔件具有用于在相邻椎骨的棘突之间定位的轴向和径向尺寸。 这些系统包括一个或多个间隔件和用于递送和展开间隔件的机械致动装置。 该方法涉及在椎间盘间隙内植入一个或多个间隔物。
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