利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

114 条记录 (耗时 0.029 秒)

    MICROFLUIDIC FEEDBACK USING IMPEDANCE DETECTION
    91.
    发明申请
    MICROFLUIDIC FEEDBACK USING IMPEDANCE DETECTION 有权
    使用阻抗检测的微流感应反馈

    公开(公告)号：US20140190830A1

    公开(公告)日：2014-07-10

    申请号：US14116553

    申请日：2012-05-08

    申请人： Ryan Sturmer ,  Vijay Srinivasan ,  Arjun Sudarsan

    发明人： Ryan Sturmer ,  Vijay Srinivasan ,  Arjun Sudarsan

    IPC分类号： G01R27/16

    CPC分类号： B01L3/50273 ,  B01L3/502792 ,  B01L2200/0621 ,  B01L2200/10 ,  B01L2200/14 ,  B01L2200/16 ,  B01L2300/0645 ,  B01L2300/0816 ,  B01L2300/0829 ,  B01L2300/087 ,  B01L2300/089 ,  B01L2400/0427 ,  G01N27/048 ,  G01R27/16

    摘要： Methods comprising measuring the impedance of the electrode produced by the excitation signal, wherein the impedance indicates presence of liquid at the electrode are disclosed. Computer readable mediums storing processor executable instructions for performing the method, and systems are also disclosed. The systems comprise a processor, memory and code stored in the memory that when executed cause the processor at least to: receive an output voltage signal, superimpose an excitation signal onto the output voltage signal to produce a superimposed signal, connect the superimposed signal to an electrode in a droplet actuator, suppress the output voltage signal, when detecting an impedance of the electrode, and measure the impedance of the electrode produced by the excitation signal, wherein the impedance indicates presence of liquid at the electrode.

    摘要翻译： 方法包括测量由激发信号产生的电极的阻抗，其中阻抗表示在电极处存在液体。 还公开了存储用于执行该方法的处理器可执行指令的计算机可读介质，以及系统。 系统包括存储在存储器中的处理器，存储器和代码，当执行时，处理器至少要使接收输出电压信号，将激励信号叠加在输出电压信号上，产生叠加信号，将叠加的信号连接到 液滴致动器中的电极，当检测到电极的阻抗时抑制输出电压信号，并测量由激励信号产生的电极的阻抗，其中阻抗表示在电极处存在液体。

    Method for fine decomposition in finite element mesh generation
    93.
    发明授权
    Method for fine decomposition in finite element mesh generation 失效
    有限元网格生成中精细分解的方法

    公开(公告)号：US4933889A

    公开(公告)日：1990-06-12

    申请号：US187715

    申请日：1988-04-29

    申请人： Siavash N. Meshkat ,  Lee R. Nackman ,  Vijay Srinivasan

    发明人： Siavash N. Meshkat ,  Lee R. Nackman ,  Vijay Srinivasan

    IPC分类号： G06F17/50 ,  G06T17/20

    CPC分类号： G06T17/20 ,  G06F17/5018

    摘要： A method for fine decomposition in finite element mesh generation, in which a polygonal boundary of a domain is input into the system by an analyst and the domain is automatically divided into rough elements generally corresponding to Voronoi regions, that is, regions which are closer to respective ones of the polygonal line segments or reflex vertices therebetween. Any arc portion of these regions is converted to a straight line. Additional lines are formed between interior vertices of the rough regions so that all rough regions are either triangles or trapezoids. Adjacent rough regions are then paired across internal boundaries and are classified into four types. The rough regions are then subdivided into fine regions of triangular shape according to rules associated with each of the four types. The degree of fine subdivision can be controlled according to known equations providing the total number of fine elements. Finite difference equations are solved on the so generated fine regions and a physical variable is displayed in pictorial form. The analyst then readjusts the domain boundary and repeats the process.

    Microfluidic feedback using impedance detection
    94.
    发明授权
    Microfluidic feedback using impedance detection 有权
    微流体反馈采用阻抗检测

    公开(公告)号：US09188615B2

    公开(公告)日：2015-11-17

    申请号：US14116553

    申请日：2012-05-08

    申请人： Ryan Sturmer ,  Vijay Srinivasan ,  Arjun Sudarsan

    发明人： Ryan Sturmer ,  Vijay Srinivasan ,  Arjun Sudarsan

    IPC分类号： G01R27/16 ,  B01L3/00

    CPC分类号： B01L3/50273 ,  B01L3/502792 ,  B01L2200/0621 ,  B01L2200/10 ,  B01L2200/14 ,  B01L2200/16 ,  B01L2300/0645 ,  B01L2300/0816 ,  B01L2300/0829 ,  B01L2300/087 ,  B01L2300/089 ,  B01L2400/0427 ,  G01N27/048 ,  G01R27/16

    摘要： Methods comprising measuring the impedance of the electrode produced by the excitation signal, wherein the impedance indicates presence of liquid at the electrode are disclosed. Computer readable mediums storing processor executable instructions for performing the method, and systems are also disclosed. The systems comprise a processor, memory and code stored in the memory that when executed cause the processor at least to: receive an output voltage signal, superimpose an excitation signal onto the output voltage signal to produce a superimposed signal, connect the superimposed signal to an electrode in a droplet actuator, suppress the output voltage signal, when detecting an impedance of the electrode, and measure the impedance of the electrode produced by the excitation signal, wherein the impedance indicates presence of liquid at the electrode.

    摘要翻译： 方法包括测量由激发信号产生的电极的阻抗，其中阻抗表示在电极处存在液体。 还公开了存储用于执行该方法的处理器可执行指令的计算机可读介质，以及系统。 系统包括存储在存储器中的处理器，存储器和代码，当执行时，处理器至少要使接收输出电压信号，将激励信号叠加在输出电压信号上，产生叠加信号，将叠加的信号连接到 液滴致动器中的电极，当检测到电极的阻抗时抑制输出电压信号，并测量由激励信号产生的电极的阻抗，其中阻抗表示在电极处存在液体。

    METHODS AND SYSTEMS FOR FAULT-TOLERANT POWER ANALYSIS
    96.
    发明申请
    METHODS AND SYSTEMS FOR FAULT-TOLERANT POWER ANALYSIS 审中-公开
    用于故障电力分析的方法和系统

    公开(公告)号：US20120166168A1

    公开(公告)日：2012-06-28

    申请号：US12978193

    申请日：2010-12-23

    申请人： Vijay Srinivasan

    发明人： Vijay Srinivasan

    IPC分类号： G06F17/50

    CPC分类号： G06F17/505 ,  G06F2217/70 ,  G06F2217/78

    摘要： Methods and systems are described which enable a user to conduct a power analysis of a behavior description of a circuit design. The elements of the circuit design are described at the register transfer level and synthesized to a gate-level netlist. Embodiments of the invention allow a user to conduct accurate power analysis during register transfer level to gate-level netlist synthesis.

    摘要翻译： 描述了使得用户能够对电路设计的行为描述进行功率分析的方法和系统。 电路设计的要素在寄存器传输级别进行描述，并合成到门级网表。 本发明的实施例允许用户在对门级网表合成的寄存器传送级别期间进行精确的功率分析。

    Protein Crystallization Droplet Actuator, System and Method
    98.
    发明申请
    Protein Crystallization Droplet Actuator, System and Method 有权
    蛋白质结晶滴液致动器，系统和方法

    公开(公告)号：US20080050834A1

    公开(公告)日：2008-02-28

    申请号：US11839762

    申请日：2007-08-16

    申请人： Vamsee Pamula ,  Vijay Srinivasan ,  Michael Pollack

    发明人： Vamsee Pamula ,  Vijay Srinivasan ,  Michael Pollack

    IPC分类号： G01N33/00 ,  B01J19/00 ,  G01N1/38

    CPC分类号： G01N23/20 ,  B01L3/06 ,  B01L3/502792 ,  B01L2200/16 ,  B01L2300/0861 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2400/0421 ,  B01L2400/0427 ,  Y10T436/25

    摘要： Protein crystallization droplet actuators, systems and methods are provided. According to one embodiment, a droplet actuator for providing an array of crystallization conditions is provided and includes: (a) two or more processing reservoirs; (b) two or more dispensing reservoirs collectively comprising two or more crystallization reagents; and (c) a port for introducing a sample for crystallization analysis. Systems including the droplet actuator, methods of providing an array of crystallization conditions, and methods of identifying crystallization conditions are also provided.

    摘要翻译： 提供蛋白质结晶液滴致动器，系统和方法。 根据一个实施例，提供了一种用于提供结晶条件阵列的液滴致动器，其包括：（a）两个或更多个处理容器; （b）两个或更多个分配容器，共同包含两种或多种结晶试剂; 和（c）用于引入用于结晶分析的样品的端口。 还提供了包括液滴致动器，提供结晶条件阵列的方法以及鉴定结晶条件的方法的系统。

    Method of generating finite elements using the symmetric axis transform
    99.
    发明授权
    Method of generating finite elements using the symmetric axis transform 失效
    使用对称轴变换生成有限元的方法

    公开(公告)号：US4797842A

    公开(公告)日：1989-01-10

    申请号：US97382

    申请日：1987-09-16

    申请人： Lee R. Nackman ,  Vijay Srinivasan

    发明人： Lee R. Nackman ,  Vijay Srinivasan

    IPC分类号： G05B19/4093 ,  G05B19/4097 ,  G06F17/10 ,  G06F17/17 ,  G06F17/50 ,  G06T17/20 ,  G06F15/60 ,  G06F15/328 ,  G06F15/62

    CPC分类号： G06T17/20 ,  G06F17/5018

    摘要： A method, amenable to automation, for generating finite elements of a geometric model. The model is first subdivided into coarse subdomains and then the coarse subdomains are further subdivided. The coarse subdivision is performed using a symmetric axis transform which generates axes symmetric to opposing boundaries of the object. The transform also generates a radius function of the axes giving the distance between the axes and the boundaries. A coarse subdomain is created between each single non-branching section of the axes and one of its associated boundaries. The fine subdivisions of the relatively simple coarse subdomains is performed by well known techniques or can beneficially use the radius function.

    摘要翻译： 一种易于自动化的方法，用于生成几何模型的有限元。 该模型首先被细分为粗略的子域，然后将粗略的子域进一步细分。 使用对称轴变换执行粗略细分，其生成与对象的相对边界对称的轴。 该变换还生成轴的半径函数，给出轴和边界之间的距离。 在轴的每个单独非分支部分和其相关联的边界之间创建粗略的子域。 相对简单的粗略子域的精细细分是通过熟知的技术进行的，或者可以有利地使用半径函数。

    Method of Reducing Liquid Volume Surrounding Beads
    100.
    发明申请
    Method of Reducing Liquid Volume Surrounding Beads 有权
    减少液体体积环绕珠的方法

    公开(公告)号：US20140057363A9

    公开(公告)日：2014-02-27

    申请号：US12992939

    申请日：2009-05-18

    申请人： Ramakrishna Sista ,  Vamsee Pamula ,  Arjun Sudarsan ,  Vijay Srinivasan ,  Prasanna Thwar

    发明人： Ramakrishna Sista ,  Vamsee Pamula ,  Arjun Sudarsan ,  Vijay Srinivasan ,  Prasanna Thwar

    IPC分类号： G01N1/40

    CPC分类号： B01L3/502792 ,  B01L3/502761 ,  B01L2200/0673 ,  B01L2300/0816 ,  B01L2300/0819 ,  B01L2300/0829 ,  B01L2300/089 ,  B01L2400/0406 ,  B01L2400/0415 ,  B01L2400/0427 ,  B01L2400/043 ,  B01L2400/0487 ,  G01N1/4077 ,  G01N35/0098 ,  G01N2035/00564 ,  Y10T436/25

    摘要： The invention provides droplet actuators and droplet actuator techniques. Among other things, the droplet actuators and methods are useful for manipulating beads on a droplet actuator, such as conducting droplet operations using bead-containing droplets on a droplet actuator. For example, beads may be manipulated on a droplet actuator in the context of executing a sample preparation protocol and/or an assay protocol. An output of the methods of the invention may be beads prepared for execution of an assay protocol. Another output of the methods of the invention may be results of an assay protocol executed using beads. Among the methods described herein are methods of concentrating beads in droplets, methods of washing beads, methods of suspending beads, methods of separating beads, methods of localizing beads within a droplet, methods of forming emulsions in which droplets include beads, methods of loading beads into a droplet operations gap of a droplet actuator, methods of organizing beads in a monolayer, and methods of capturing, trapping or restraining beads.

    摘要翻译： 本发明提供了液滴致动器和液滴致动器技术。 除其他之外，液滴致动器和方法可用于操纵液滴致动器上的珠，例如使用液滴致动器上的含珠液滴进行液滴操作。 例如，在执行样品制备方案和/或测定方案的上下文中，珠可以在液滴致动器上操作。 本发明方法的输出可以是准备用于执行测定方案的珠粒。 本发明方法的另一个输出可以是使用珠子执行的测定方案的结果。 在本文描述的方法中，将珠粒集中在液滴中的方法，洗涤珠粒的方法，悬浮珠粒的方法，分离珠粒的方法，在液滴内定位珠粒的方法，形成液滴包括珠粒的乳液的方法，加载珠粒的方法 液滴致动器的液滴操作间隙，单层组织珠粒的方法，以及捕获，捕获或抑制珠粒的方法。