PROBE FOR LOCALIZED NEURAL OPTOGENETICS STIMULATION AND NEUROCHEMISTRY RECORDINGS

    公开(公告)号:US20180193663A1

    公开(公告)日:2018-07-12

    申请号:US15403651

    申请日:2017-01-11

    Abstract: A neural probe is presented for local neural optogenetics stimulation and neurochemistry recordings. The neural probe includes a probe body, a shank extending from the probe body to a tip, a plurality of micro light-emitting diodes (LEDs) positioned across a length of a first surface of the shank for providing neuron-affecting light, a plurality of carbon devices, and a plurality of carbon electrodes positioned across a length of a second surface of the shank, the second surface in opposed relation to the first surface. The plurality of carbon electrodes can be vertically aligned carbon nanotubes or vertically aligned carbon nanofibers. The plurality of carbon electrodes can also be horizontally aligned carbon nanotubes. The plurality of micro LEDs activate neurons and the plurality of vertically aligned carbon electrodes electrochemically record neurotransmitters.

    FLEXIBLE NEURAL PROBES
    106.
    发明申请

    公开(公告)号:US20180078193A1

    公开(公告)日:2018-03-22

    申请号:US15268020

    申请日:2016-09-16

    Inventor: Shu-Jen Han

    Abstract: Embodiments include microelectrodes including a flexible shank and a bioabsorbable material surrounding the flexible shank. The flexible shank can include a flexible substrate, a circuit, and a plurality of sensors. Embodiments also include a methods of forming flexible active electrode arrays including depositing a flexible polymer on a substrate. The methods also include forming a plurality of sensors on the flexible polymer and attaching a silicon-based chip to the flexible shank. The methods also include coating the flexible shank in a bioabsorbable material and cutting the shank and a portion of the bioabsorbable material from the substrate.

    FLEXIBLE NEURAL PROBES
    107.
    发明申请

    公开(公告)号:US20180078162A1

    公开(公告)日:2018-03-22

    申请号:US15474198

    申请日:2017-03-30

    Inventor: Shu-Jen Han

    Abstract: Embodiments include microelectrodes including a flexible shank and a bioabsorbable material surrounding the flexible shank. The flexible shank can include a flexible substrate, a circuit, and a plurality of sensors. Embodiments also include a methods of forming flexible active electrode arrays including depositing a flexible polymer on a substrate. The methods also include forming a plurality of sensors on the flexible polymer and attaching a silicon-based chip to the flexible shank. The methods also include coating the flexible shank in a bioabsorbable material and cutting the shank and a portion of the bioabsorbable material from the substrate.

    Remote sensing using pulse-width modulation

    公开(公告)号:US09835583B2

    公开(公告)日:2017-12-05

    申请号:US14695205

    申请日:2015-04-24

    CPC classification number: G01N27/4141 G01N27/4146 G01N33/0075

    Abstract: A method of assembling a remote sensor system to detect a gas or chemical and a remote sensor system are described. The method includes fabricating a sensor, the sensor outputting a sensor signal that changes upon contact of the sensor with the gas or chemical and the sensor having an input port for a clock signal, coupling a capacitor to the sensor, the capacitor output voltage resulting from the sensor signal output by the sensor, and coupling a mixer to the capacitor and a low frequency oscillator, the mixer configured to mix the capacitor output voltage with the low frequency oscillator output to generate an output signal. The method also includes coupling an antenna to the mixer, the antenna configured to transmit the output signal indicating detection of the gas or chemical.

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