中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

583 records (took 0.024 seconds)

    Universal filter plate
    111.
    发明授权
    Universal filter plate 有权
    通用过滤板

    公开(公告)号：US08182766B2

    公开(公告)日：2012-05-22

    申请号：US12658569

    申请日：2010-02-08

    Applicant: Stephane Jean Marie Olivier ,  Gerard Muller ,  Jeffery S. Busnach

    Inventor： Stephane Jean Marie Olivier ,  Gerard Muller ,  Jeffery S. Busnach

    IPC: B01L3/00

    CPC classification number: B01L3/50255 ,  B01L2200/02 ,  B01L2200/12 ,  B01L2300/0829 ,  B01L2400/0409 ,  B01L2400/0487

    Abstract: The present invention relates to a multiwell plate having a series of wells, each well having an inner bore, an open top and a bottom, the bottom being sealed with a liquid permeable filter, and an insert contained within the inner bore of each well, each insert having an outer dimension the same or larger than that of the inner bore and a through bore of a dimension less than that of the outer dimension of the insert. The use of inserts allows one to take a standard one-piece plate design with a heat sealed membrane and arrange for a universal plate format. The insert may act as a base for an extension plate that can be adhered, heat sealed or overmolded over the plate top and insert top to form a deep well plate. The plate conforms to the Society of Biological Standards Microplate Standards. Additionally, the inserts may be configured to give one a different well diameter (smaller, tapered, etc), to include various media such as chromatography resins, to include multiple layers of membrane and the like. A variety of inserts may be used in the same plate to create a minilab on a plate that is capable of conducting several steps of a process on the same (e.g (e.g. filter, wash, bind, elute, label, etc).

    Abstract translation: 本发明涉及具有一系列井的多孔板，每个孔具有内孔，开口顶部和底部，底部用液体可渗透的过滤器密封，以及包含在每个孔的内孔内的插入件， 每个插入件具有与内孔相同或更大的外部尺寸和尺寸小于插入件的外部尺寸尺寸的通孔。 使用插入件可以使用带有热密封膜的标准单片板设计，并安排通用板格式。 插入件可以用作延伸板的基部，该延伸板可以在板顶上粘附，热密封或包覆成型，并且插入顶部以形成深孔板。 该板符合生物标准微孔板标准协会。 此外，插入件可以被配置成给出一个不同的孔直径（更小，锥形等），以包括各种介质，例如色谱树脂，以包括多层膜等。 可以在同一板中使用各种插入物以在板上产生能够在相同的过程上进行几个步骤（例如过滤器，洗涤，结合，洗脱，标记等）的小拉伸。

    Method and apparatus for making porous agarose beads
    112.
    发明授权
    Method and apparatus for making porous agarose beads 有权
    制备多孔琼脂糖珠的方法和设备

    公开(公告)号：US08177537B2

    公开(公告)日：2012-05-15

    申请号：US12660708

    申请日：2010-03-02

    Applicant: Kwok-Shun Cheng ,  Senthilkumar Ramaswamy ,  Nanying Bian ,  Brian Gagnon ,  Umana Joaquin ,  Neil Soice

    Inventor： Kwok-Shun Cheng ,  Senthilkumar Ramaswamy ,  Nanying Bian ,  Brian Gagnon ,  Umana Joaquin ,  Neil Soice

    IPC: B29B9/00

    CPC classification number: B01J20/24 ,  B01J13/04 ,  B01J20/28009 ,  B01J20/285 ,  B01J20/286 ,  B01J20/291 ,  B01J20/3204 ,  B01J20/3242 ,  B01J20/3244 ,  B01J20/3272 ,  B01J20/328 ,  B01J20/3282 ,  B01J20/3289 ,  B01J20/3293 ,  B01J2220/4825

    Abstract: The present invention relates to a method and apparatus for forming agarose or cored agarose beads. The process involves dissolving/gelation the agarose in a suitable liquid, mixing it with a hydrophobic liquid to form an emulsion and maintaining that emulsion at a temperature equal to or greater than the gelation point of the agarose, passing it through a static mixer to create agarose droplets and solidifying the agarose droplets in a second bath of hydrophobic liquid. The beads can then be washed and used or further processed to crosslink the agarose and/or add various functionalities on to the agarose. Another method for solidifying the agarose droplets is by using a heat exchanger to cool the stream continuously after it exits the static mixer. A similar process is used for the “cored” beads except cores, preferably in bead form, are introduced to the agarose before it enters the first hydrophobic liquid so that the agarose forms a coating on the cores. A similar process with either agarose beads (made by this or another process) or cored agarose (made by this or another process) can be used to add multiple layers of agarose on to the existing beads. An apparatus for running the process is also disclosed.

    Abstract translation: 本发明涉及用于形成琼脂糖或核心琼脂糖珠的方法和装置。 该方法包括将琼脂糖溶解/凝胶化在合适的液体中，将其与疏水性液体混合以形成乳液，并将该乳液保持在等于或大于琼脂糖凝胶点的温度，将其通过静态混合器以产生 琼脂糖滴并在第二浴疏水性液体中固化琼脂糖滴。 然后可以将珠子洗涤并使用或进一步加工以使琼脂糖交联和/或在琼脂糖上添加各种功能。 用于固化琼脂糖滴的另一种方法是通过使用热交换器在离开静态混合器之后连续冷却流。 对于“核心”珠粒，使用类似的方法，除了核心，优选以珠粒形式，在其进入第一疏水性液体之前将其引入琼脂糖，使得琼脂糖在芯上形成涂层。 可以使用与琼脂糖珠（由该方法或另一方法制备）或核心琼脂糖（由该方法或另一方法制备）相似的方法将多层琼脂糖添加到现有珠粒上。 还公开了一种用于运行该过程的装置。

    Filter with memory, communication and concentration sensor
    113.
    发明授权
    Filter with memory, communication and concentration sensor 有权
    过滤器内存，通讯和浓度传感器

    公开(公告)号：US08147757B2

    公开(公告)日：2012-04-03

    申请号：US12969677

    申请日：2010-12-16

    Applicant: Anthony DiLeo

    Inventor： Anthony DiLeo

    IPC: G01N15/06

    CPC classification number: B01D35/143 ,  A61M2205/7509 ,  B01D29/60 ,  B01D61/22 ,  B01D65/104 ,  B01D2201/291 ,  B01D2311/08 ,  B01D2311/14 ,  B01D2311/246 ,  G01N15/0618 ,  G01N2015/084 ,  G01N2035/00811 ,  Y10S210/905 ,  Y10T436/115831 ,  Y10T436/25375

    Abstract: The present invention describes a system and method for accurately measuring the concentration of a substance within a filter housing. A concentration sensor and a communications device are coupled so as to be able to measure and transmit the concentration of a particular substance within the filter housing while in use. This system can comprise a single component, integrating both the communication device and the concentration sensor. Alternatively, the system can comprise separate sensor and transmitter components, in communication with one another. In yet another embodiment, a storage element can be added to the system, thereby allowing the device to store a set of concentration values. The use of this device is beneficial to many applications. For example, the ability to read concentration values in situ allows integrity tests to be performed without additional equipment.

    Abstract translation: 本发明描述了一种用于精确测量过滤器壳体内物质浓度的系统和方法。 浓度传感器和通信装置被耦合以便能够在使用中测量和传输过滤器壳体内的特定物质的浓度。 该系统可以包括集成通信设备和浓度传感器的单个组件。 或者，系统可以包括彼此通信的分离的传感器和发射器部件。 在另一个实施例中，可以将存储元件添加到系统，从而允许设备存储一组浓度值。 使用此设备有利于许多应用程序。 例如，原位读取浓度值的能力允许在没有附加设备的情况下执行完整性测试。

    Fluid transfer system for isolators
    117.
    发明授权
    Fluid transfer system for isolators 有权

    公开(公告)号：US12194454B2

    公开(公告)日：2025-01-14

    申请号：US17609008

    申请日：2020-08-06

    Applicant: EMD MILLIPORE CORPORATION

    Inventor： Martin Morrissey ,  Conor King ,  Philip Borozenets

    IPC: B01L1/04 ,  B25J21/00 ,  B25J21/02

    Abstract: An apparatus for use with an isolator, including a crown for releasably joining with a beta port of the isolator, wherein the crown includes at least one anchoring support; a spring hook on at least one end of the at least one anchoring support; a needle block including at least one through hole for having a needle positioned therein, wherein the at least one needle is joined with tubing; a yoke; and a biasing element releasably joined with the yoke and the at least one anchoring support; wherein the needle block is releasably joined to the crown.

    HOLLOW SHAFT IMPELLER
    118.
    发明申请
    HOLLOW SHAFT IMPELLER 有权

    公开(公告)号：US20240367122A1

    公开(公告)日：2024-11-07

    申请号：US18687944

    申请日：2022-11-16

    Applicant: EMD Millipore Corporation

    Inventor： Sualyneth Galarza ,  Anne Hansen ,  Amy Mei ,  Amy Wood ,  James J. Vigna ,  Marisa Maher

    IPC: B01F27/2122 ,  B01F27/17 ,  B01F33/453

    Abstract: A hollow shaft impeller (100) having a hollow impeller housing (120), a magnet (108), an impeller cap (102), an impeller retainer (106), and a plurality of impeller blades (134). The impeller housing has a hub (130) that defines an interior volume (128) and an impeller bore that provides access to the interior volume. The magnet may be sized to be disposed within the interior volume. The impeller cap may be removably coupled to the hollow impeller housing proximate to the impeller bore. The impeller retainer may be removably coupled to the magnet and sized to be disposed within the interior volume. The plurality of impeller blades may project from the hub. Optionally, fins (140) may be disposed on each of the plurality of impeller blades.

Patent Agency Ranking