公开(公告)号：US20160287788A1

公开(公告)日：2016-10-06

申请号：US14392399

申请日：2014-11-17

申请人： DUOJECT MEDICAL SYSTEMS INC.

发明人： Yan Tremblay ,  Sylvain Cloutier ,  Simon Hamel

IPC分类号： A61M5/20 ,  A61M5/24 ,  A61M5/32 ,  A61M5/315

CPC分类号： A61M5/2033 ,  A61M5/002 ,  A61M5/24 ,  A61M5/31576 ,  A61M5/3202 ,  A61M5/326 ,  A61M2005/206 ,  A61M2005/208 ,  A61M2005/247 ,  A61M2005/31588 ,  A61M2202/048 ,  A61M2205/3553 ,  A61M2205/50 ,  A61M2205/8206

摘要： An auto-injector pen has an outer housing (12, 14) which has a proximal end (18) and a distal end (16), an inner housing (84) having a cartridge (74) therein, the cartridge (74) containing a medicament and having one end thereof sealed by pierceable member (80), a needle hub (64) having first and second piercing tips (68, 70) which are in fluid communication, an actuating assembly (28) which moves an actuator from a first position to an activated position wherein the first piercing tip (68) extends outwardly of the outer housing (12,14) at the proximal end (18) and the second piercing tip (70) pierces the pierceable member (80), a first trigger (22) located at the distal end (16) and a second trigger (98) located at proximal end 18, the arrangement being such that the second trigger 98 must be activated to permit activation of the first trigger (22).

摘要翻译： 自动注射器笔具有外壳（12,14），其具有近端（18）和远端（16），内壳体（84）在其中具有盒（74），所述盒（74）包含 一种药物，其一端由可刺破构件（80）密封;具有第一和第二穿孔尖端（68,70）的针座（64），其具有流体连通;致动组件，使致动器从 第一穿刺尖端（68）在所述近端（18）处从所述外壳体（12,14）向外延伸，并且所述第二刺穿尖端（70）刺穿所述可刺破构件（80），所述第一刺穿尖端 位于远端（16）的触发器（22）和位于近端18处的第二触发器（98），该布置使得第二触发器98必须被激活以允许第一触发器（22）的激活。

公开(公告)号：US20160271328A1

公开(公告)日：2016-09-22

申请号：US15075277

申请日：2016-03-21

申请人： Covidien LP

发明人： David Selvitelli ,  Edward Brundidge, III ,  Mark Callahan ,  Jeffrey Delnickas ,  Teshtar Elavia ,  Melvin Finke ,  Viviana Guerriero ,  Loredana Jinga ,  Brian Sharp ,  Kathleen Tremblay

IPC分类号： A61M5/315 ,  A61M5/31

CPC分类号： A61M5/3159 ,  A61C5/62 ,  A61M5/19 ,  A61M5/24 ,  A61M5/3129 ,  A61M5/3134 ,  A61M5/3137 ,  A61M5/3148 ,  A61M5/31511 ,  A61M5/31591 ,  A61M5/3205 ,  A61M5/3216 ,  A61M5/3243 ,  A61M5/3286 ,  A61M5/3291 ,  A61M5/3298 ,  A61M5/34 ,  A61M5/344 ,  A61M5/484 ,  A61M5/488 ,  A61M2005/247 ,  A61M2005/3139 ,  A61M2005/31598 ,  A61M2005/3267 ,  A61M2005/341 ,  A61M2202/048 ,  A61M2205/585 ,  A61M2205/586 ,  A61M2205/587 ,  A61M2205/59

摘要： A syringe assembly for dispensing medicine from a cartridge having a diaphragm and a piston opposite the diaphragm. The assembly includes a barrel having a hollow interior, an open proximal end, a closed distal end, and an outlet. The assembly also includes a cartridge receiver slidably receivable in the hollow interior of the barrel. The receiver includes an interior space for receiving the cartridge, an access needle extending into the interior space for puncturing the diaphragm of the cartridge. The access needle directs fluid to the barrel outlet. The cartridge receiver includes a plunger rod movable into the interior space of the cartridge receiver for engaging the piston of the cartridge to selectively force medicine in the cartridge through the access needle.

摘要翻译： 一种用于从具有隔膜的药筒和与隔膜相对的活塞分配药物的注射器组件。 组件包括具有中空内部的筒，敞开的近端，封闭的远端和出口。 组件还包括可滑动地接收在筒的中空内部的盒式存储器。 接收器包括用于接收盒的内部空间，延伸到内部空间中的用于刺穿盒的隔膜的入口针。 进出针将流体引导到筒出口。 盒式存储器包括可移动到盒式存储器的内部空间中的柱塞杆，用于接合盒的活塞，以通过接入针选择性地迫使盒中的药物。

公开(公告)号：US20150224253A1

公开(公告)日：2015-08-13

申请号：US14696644

申请日：2015-04-27

申请人： MEDIMOP Medical Projects Ltd.

发明人： Oz CABIRI

IPC分类号： A61M5/145 ,  A61M5/158 ,  A61M5/172 ,  A61M5/142

CPC分类号： A61M5/14248 ,  A61J1/1406 ,  A61M5/14244 ,  A61M5/1452 ,  A61M5/14566 ,  A61M5/158 ,  A61M5/172 ,  A61M5/283 ,  A61M5/3146 ,  A61M2005/14208 ,  A61M2005/14252 ,  A61M2005/14256 ,  A61M2005/14268 ,  A61M2005/14533 ,  A61M2005/14573 ,  A61M2005/1581 ,  A61M2005/247 ,  A61M2005/2474 ,  A61M2205/123

摘要： A method and apparatus are disclosed for delivery of a drug to a recipient. In some embodiments, the delivery apparatus may unseal a drug containing reservoir. In some embodiments, the delivery rate may be controlled and/or adjustable. Optionally the apparatus may be disposable. Optionally, the apparatus may have a low profile and/or be wearable and/or attachable to the recipient. Optionally, discharge of the drug and/or unsealing of the reservoir may be driven by a plunger moving parallel to the base of the apparatus. Optionally, the apparatus may release a hypodermic needle into the recipient. Optionally, release of the hypodermic needle may be in a direction non-parallel and/or orthogonal to the direction of movement of the plunger. Optionally, prior to release, the hypodermic needle may be preserved in an aseptic state by a needle opening septum sealing a needle opening. Optionally, upon release, the hypodermic needle may pierce the needle opening septum.

公开(公告)号：US09072841B2

公开(公告)日：2015-07-07

申请号：US13988989

申请日：2011-11-28

申请人： Thomas Urs Thueer ,  David Richard Mercer ,  Garen Kouyoumjian ,  Malcolm Stanley Boyd

发明人： Thomas Urs Thueer ,  David Richard Mercer ,  Garen Kouyoumjian ,  Malcolm Stanley Boyd

IPC分类号： A61M31/00 ,  A61M5/32 ,  A61M5/24 ,  A61M5/31 ,  A61M5/34 ,  A61M5/178

CPC分类号： A61M5/3294 ,  A61M5/2448 ,  A61M5/2466 ,  A61M5/3146 ,  A61M5/326 ,  A61M5/347 ,  A61M2005/1787 ,  A61M2005/247 ,  A61M2005/2474 ,  A61M2005/3247 ,  A61M2005/3267 ,  A61M2205/581 ,  A61M2205/584

摘要： A medicated module for an injection system to co-deliver at least two medicaments is disclosed where a primary delivery device containing a primary medicament accepts a medicated module containing a single dose of a secondary medicament and where both medicaments are delivered through a hollow needle. The medicated module does not require the user to manually engage a reservoir containing the secondary medicament. Instead, a biasing member automatically activates the reservoir when the needle guard is retracted. The needle guard prevents accidental needle sticks before and after an injection, and locks after dose delivery.

摘要翻译： 公开了一种用于共同递送至少两种药物的注射系统的药物组合物，其中包含主要药物的主要递送装置接受含有单剂量次级药物的药物组合物，并且其中两种药物通过中空针体递送。 加药模块不需要用户手动接合包含辅助药剂的储存器。 相反，当针护罩缩回时，偏置构件自动启动储存器。 针头防护装置防止注射前后的意外针刺，并在给药后锁定。

公开(公告)号：US20150150760A1

公开(公告)日：2015-06-04

申请号：US14406200

申请日：2013-06-13

申请人： Alexander Markus Oelz ,  Robert James Martin

发明人： Alexander Markus Oelz ,  Robert James Martin

IPC分类号： A61J7/00

CPC分类号： A61J7/0053 ,  A61M5/001 ,  A61M5/19 ,  A61M5/2466 ,  A61M5/315 ,  A61M5/5086 ,  A61M2005/2407 ,  A61M2005/2411 ,  A61M2005/247 ,  A61M2005/2477 ,  A61M2005/3121 ,  A61M2005/31506 ,  A61M2005/31516 ,  A61M2205/3331 ,  A61M2205/6045

摘要： A liquid dispensing system for oral administration comprises a dispenser and cartridges from which medicine is dispensed. Each cartridge includes a hollow shell with a septum at one end, a piston at the other end, and the medicine in a cavity between the septum and the piston. The dispenser includes receiver in which a cartridge is received, a plunger that can slide relative to the receiver and that has a plunging head that can drive the piston, and a barrel in which the cartridge, receiver and plunger can be received, at least partly. Once a cartridge has been inserted into the receiver, the receiver and cartridge are inserted into the barrel and a piercing head ruptures the septum. The plunger is pushed to drive the piston and the medicine is dispensed by the piston, through a discharge passage of the barrel.

摘要翻译： 用于口服给药的液体分配系统包括分配器和分配药物的药筒。 每个药筒包括一个中空的外壳，其一端具有隔膜，在另一端具有一个活塞，以及在隔膜和活塞之间的空腔中的药物。 分配器包括容纳盒的接收器，可相对于接收器滑动并且具有能够驱动活塞的插入头的柱塞和可以容纳盒，接收器和柱塞的桶，至少部分地 。 一旦将墨盒插入接收器中，接收器和墨盒被插入到镜筒中，并且穿刺头部破裂隔膜。 柱塞被推动以驱动活塞，药物由活塞通过筒的排放通道分配。

公开(公告)号：US20150073353A1

公开(公告)日：2015-03-12

申请号：US14481377

申请日：2014-09-09

申请人： Covidien LP

发明人： David L. Strader

IPC分类号： A61M5/24 ,  A61L2/08 ,  A61L2/10 ,  A61M5/32

CPC分类号： A61M5/2466 ,  A61L2/081 ,  A61L2/10 ,  A61M5/24 ,  A61M5/31578 ,  A61M5/3202 ,  A61M2005/2073 ,  A61M2005/247 ,  Y10T29/4984

摘要： The disclosed embodiment relates to an injection device that is a single patient use, disposable device containing a needle and a cartridge containing a drug or pharmaceutical product. The device is initially provided in a pre-armed configuration wherein the needle sheath maintains cantilever locking tabs on the housing in a position to the maintain the needle in a position separated from the septum of a cartridge. To arm the device, the practitioner removes the needle sheath and pushes down the plunger assembly. The cantilever locking tabs flex outwardly thereby allowing the cartridge-to-housing interface and the cartridge to move forward whereby the butt end of the needle punctures the septum of the cartridge. Additionally, the cantilever locking tabs form a stop configuration with the housing of the device. The disclosed embodiment is particularly adaptable to dental anesthetic applications, as well as other medical and veterinary applications.

摘要翻译： 所公开的实施例涉及一种单一患者使用的注射装置，包含针的一次性装置和包含药物或药物产品的药筒。 该装置最初以预先布置的配置提供，其中针护套将壳体上的悬臂锁定突片保持在将针保持在与药筒的隔膜分离的位置的位置。 为了使装置固定，从业者将移除针鞘并推下柱塞组件。 悬臂锁定片向外弯曲，从而允许盒与壳体之间的接口向前移动，由此针的对接端刺穿盒的隔膜。 此外，悬臂锁定突片与装置的外壳形成停止构型。 所公开的实施例特别适用于牙科麻醉应用以及其他医学和兽医学应用。

公开(公告)号：US20130253465A1

公开(公告)日：2013-09-26

申请号：US13988315

申请日：2011-11-28

申请人： Marc Holtwick ,  Zdenek Cerman ,  David Martin Leak ,  Malcolm Stanley Boyd ,  Daniel Thomas De Sausmarez Lintell ,  David Saunders

发明人： Marc Holtwick ,  Zdenek Cerman ,  David Martin Leak ,  Malcolm Stanley Boyd ,  Daniel Thomas De Sausmarez Lintell ,  David Saunders

IPC分类号： A61M5/19

CPC分类号： A61M5/19 ,  A61M5/14244 ,  A61M5/1452 ,  A61M5/16827 ,  A61M5/20 ,  A61M5/2066 ,  A61M2005/2407 ,  A61M2005/247 ,  A61M2005/2496 ,  A61M2005/3125 ,  A61M2005/3126 ,  A61M2005/3128 ,  A61M2205/3584 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/6072 ,  A61M2205/8206

摘要： A dispense interface component for use with a drug delivery device is provided. The dispense interface component may include a main body, a first piercing portion, a second piercing portion, and a biasing element. The main body is configured for connection to the drug delivery device. The first piercing portion is for piercing a first cartridge contained within the drug delivery device, and the first piercing portion is connected to the main body. The second piercing portion is for piercing a second cartridge contained with the drug delivery device, and the second piercing portion is connected to the main body. The at least one biasing element is operably coupled to the main body, wherein the at least one biasing element is configured to, when the load on the at least one biasing element is less than or equal to a threshold load, bias (i) the first piercing portion away from the first cartridge and (ii) the second piercing portion away from the second cartridge.

摘要翻译： 提供了一种用于药物输送装置的分配界面部件。 分配界面部件可以包括主体，第一穿刺部分，第二穿刺部分和偏置元件。 主体被配置为连接到药物输送装置。 第一刺穿部分用于刺穿容纳在药物输送装置内的第一药筒，并且第一穿刺部分连接到主体。 第二穿刺部分用于刺穿包含药物输送装置的第二药筒，第二穿刺部分连接到主体。 所述至少一个偏置元件可操作地联接到所述主体，其中所述至少一个偏置元件构造成当所述至少一个偏置元件上的负载小于或等于阈值负载时，偏置（i） 第一穿刺部分远离第一药筒，和（ii）第二穿刺部分远离第二药筒。

公开(公告)号：US20130110053A1

公开(公告)日：2013-05-02

申请号：US13807401

申请日：2011-06-20

申请人： Keisuke Yoshino ,  Miyuki Koyama

发明人： Keisuke Yoshino ,  Miyuki Koyama

IPC分类号： A61M5/32 ,  A61J1/14

CPC分类号： A61M5/3286 ,  A61J1/1406 ,  A61M5/2425 ,  A61M5/2459 ,  A61M5/46 ,  A61M37/00 ,  A61M2005/247

摘要： A drug injection apparatus includes a drug container, a needle tube having a first needle tip and a second needle tip, a needle-holding portion which holds the central portion of the needle tube, and a drug container mount from which the second needle tip projects. The drug container has a container body, having a contact portion to be penetrated by the second needle tip and a pressing portion that faces the contact portion, wherein the pressing portion is to be pressed toward the contact portion side so as to deform; a seal member attached to a portion of the contact portion to be penetrated by the second needle tip, and adapted to be brought into close contact with the circumferential surface of the needle tube in liquid-tight manner; and a protective plate adapted to avoid the pressing portion from being penetrated by second needle tip inserted into the container body.

摘要翻译： 药物注射装置包括药物容器，具有第一针尖和第二针尖的针管，保持针管的中心部的针保持部和第二针尖突出的药物容器座 。 药物容器具有容纳体，具有被第二针尖贯穿的接触部和面向接触部的按压部，其中，按压部朝向接触部侧按压而变形; 所述密封构件附接到所述第二针尖所穿过的所述接触部分的一部分，并且能够以液密方式与所述针管的周面紧密接触; 以及适于避免按压部分被插入到容器主体中的第二针尖穿透的保护板。

公开(公告)号：US20130018311A1

公开(公告)日：2013-01-17

申请号：US13546454

申请日：2012-07-11

申请人： C. Garyen Denning ,  Theodore J. Mosler ,  David L. Foshee ,  Robert C. Hall ,  Andrew J. Corson

发明人： C. Garyen Denning ,  Theodore J. Mosler ,  David L. Foshee ,  Robert C. Hall ,  Andrew J. Corson

IPC分类号： A61M5/50

CPC分类号： A61M5/2429 ,  A61M5/2448 ,  A61M5/2466 ,  A61M5/3134 ,  A61M5/3137 ,  A61M5/31515 ,  A61M5/31525 ,  A61M5/31568 ,  A61M5/3158 ,  A61M5/347 ,  A61M5/50 ,  A61M5/502 ,  A61M2005/1787 ,  A61M2005/2407 ,  A61M2005/247 ,  A61M2005/3101 ,  A61M2005/3104 ,  A61M2005/3114 ,  A61M2039/2486 ,  A61M2205/585

摘要： A fluid delivery device includes a cartridge and a syringe. The cartridge includes a housing and a stopper positioned within a fluid chamber defined by the housing. The syringe includes a needle, and an outer body and an inner core which cooperate to receive at least a portion of the housing. When the fluid delivery device is in a first configuration, at least a portion of the cartridge is positioned within the syringe and the stopper is connected to the inner core. In a second configuration, a lumen defined by the needle is in fluid communication with the fluid chamber. The inner core and stopper are movable distally relative to the outer body and needle as the fluid delivery device is transitioned from the first to the second configuration. In a third configuration, the cartridge and syringe cooperate to disable the fluid delivery device.

摘要翻译： 流体输送装置包括药筒和注射器。 盒包括壳体和定位在由壳体限定的流体室内的止动件。 注射器包括针，以及配合以容纳壳体的至少一部分的外主体和内芯。 当流体输送装置处于第一构型时，药筒的至少一部分位于注射器内，止动器连接到内芯。 在第二构造中，由针限定的内腔与流体室流体连通。 当流体输送装置从第一构型转变到第二构型时，内芯和止动件相对于外体和针可相对于远端运动。 在第三种配置中，盒和注射器配合以禁用流体输送装置。

公开(公告)号：US08123724B2

公开(公告)日：2012-02-28

申请号：US11458114

申请日：2006-07-18

申请人： Richard David Gillespie, III

发明人： Richard David Gillespie, III

IPC分类号： A61M5/20 ,  A61M5/315 ,  A61M5/00 ,  A61M5/32 ,  A61M5/24

CPC分类号： A61M5/2033 ,  A61M5/2459 ,  A61M5/2466 ,  A61M5/3202 ,  A61M5/326 ,  A61M2005/206 ,  A61M2005/247 ,  A61M2005/3123 ,  A61M2005/31516

摘要： An auto-injection syringe is provided that includes an injection assembly and a retraction assembly operatively securable to the injection assembly. The retraction assembly includes a hypodermic needle having a needle hub, an end cap having a lower seal through which a portion of the hypodermic needle can pass, a retraction spring disposed between the needle hub and the end cap and maintained in a partially compressed condition therebetween, an upper seal urged against a facially sealing surface of the retraction assembly by the force of the retraction spring on the needle hub so that a sealed area is defined between the upper and lower seals, and a vent device in fluid communication with the sealed area for pressure equalization between the sealed area and an exterior of the retraction assembly.

摘要翻译： 提供一种自动注射注射器，其包括可操作地固定到注射组件的注射组件和缩回组件。 缩回组件包括具有针座的皮下注射针，端盖具有下部密封件，一部分皮下注射针可穿过该密封件，设置在针毂和端盖之间的缩回弹簧，并在其间保持部分压缩状态 通过针座上的回缩弹簧的力将上密封件推靠在收缩组件的面密封表面上，使得在上密封件和下密封件之间限定密封区域，以及与密封区域流体连通的排气装置 用于在密封区域和收缩组件的外部之间的压力平衡。