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    Reactive Self-Indicating Absorbent Materials, Methods, and Systems
    182.
    发明申请
    Reactive Self-Indicating Absorbent Materials, Methods, and Systems 审中-公开
    反应性自我指示吸收材料，方法和系统

    公开(公告)号：US20160256851A1

    公开(公告)日：2016-09-08

    申请号：US15155738

    申请日：2016-05-16

    Applicant: Leidos, Inc.

    Inventor： Thomas Grant Glover

    IPC: B01J20/06 ,  B01D46/00 ,  B01J20/28

    CPC classification number: B01J20/06 ,  B01D46/0086 ,  B01J20/28009 ,  G01N27/403 ,  G01N27/72 ,  G01N33/5438

    Abstract: The present disclosure relates, according to some embodiments, reactive self-indicating adsorbent materials, methods, and systems. A system may comprise, for example, a reactive self-indicating adsorbent material, wherein the reactive self-indicating adsorbent material comprises at least one super paramagnetic particle and a semi permeable support, wherein the at least one super paramagnetic particle is configured such that at least one magnetic property of the at least one super paramagnetic particle changes upon contact with an adsorbate; and/or at least one detector configured and arranged to detect the at least one magnetic property. In some embodiments, a method for assessing the performance and/or remaining life of an adsorbent material may comprise (a) contacting a fluid comprising an adsorbate with the adsorbent material under conditions that permit the adsorbate to contact the at least one super paramagnetic particle, wherein a change in a magnetic property of the at least one super paramagnetic particle occurs upon contact with the adsorbate; (b) detecting the magnetic property of the at least one super paramagnetic particle; and/or (c) comparing the detected magnetic property to a reference to produce an assessment of the performance and/or remaining life of the adsorbent material.

    Abstract translation: 本公开涉及根据一些实施方案的反应性自显示吸附剂材料，方法和系统。 系统可以包括例如反应性自显示吸附剂材料，其中反应性自显示吸附材料包含至少一个超顺磁性颗粒和半渗透性支持物，其中所述至少一个超顺磁性颗粒被配置成使得在 所述至少一个超顺磁性粒子的至少一个磁性随接触物而变化; 和/或至少一个检测器，其被配置和布置成检测所述至少一个磁性。 在一些实施方案中，用于评估吸附材料的性能和/或剩余寿命的方法可以包括（a）在允许被吸附物与至少一个超顺磁性颗粒接触的条件下使含有被吸附物质的流体与吸附材料接触， 其中所述至少一个超顺磁性颗粒的磁性的变化在与所述被吸附物接触时发生; （b）检测所述至少一个超顺磁性粒子的磁性; 和/或（c）将检测的磁性与参考值进行比较，以产生吸附材料的性能和/或剩余寿命的评估。

    Wideband Beamformer System
    183.
    发明申请
    Wideband Beamformer System 有权
    宽带波束成形系统

    公开(公告)号：US20160254830A1

    公开(公告)日：2016-09-01

    申请号：US15149417

    申请日：2016-05-09

    Applicant: Leidos, Inc.

    Inventor： Leo James Corbalis ,  David Scott Illar

    IPC: H04B1/12 ,  H04B7/06

    CPC classification number: H04B1/123 ,  H04B7/0617 ,  H04B7/08

    Abstract: An adaptive phased-array processing solution, referred to as the Wideband Beamformer System (WBS), demonstrates an improvement in the range and quality of air link surveillance downlink wireless cell radio signals. The WBS applies wideband frequency-domain adaptive beamforming to preprocess the dense RF signal environment, minimizing co-channel interference (CCI) from each signal, and then reconstructing a “clean” version of the signal for input to the existing surveillance receiver(s).

    Abstract translation: 称为宽带波束成形器系统（WBS）的自适应相控阵处理解决方案显示了空中链路监视下行无线小区无线电信号的范围和质量的改善。 WBS应用宽带频域自适应波束成形来预处理密集RF信号环境，最小化来自每个信号的同信道干扰（CCI），然后重建信号的“干净”版本以输入到现有监视接收机 。

    Portable Fluidic Platform For Rapid Cell-Free Production of Protein Biologics
    184.
    发明申请
    Portable Fluidic Platform For Rapid Cell-Free Production of Protein Biologics 有权
    便携式流体平台，用于快速无细胞生产蛋白质生物制剂

    公开(公告)号：US20160230203A1

    公开(公告)日：2016-08-11

    申请号：US15010528

    申请日：2016-01-29

    Applicant: Leidos, Inc.

    Inventor： John Dresios ,  Richard Holmes Griffey ,  Challise J. Sullivan ,  Erik D. Pendleton ,  Henri M. Sasmor ,  William L. Hicks ,  Eric M. Amendt

    IPC: C12P21/00 ,  C07K14/505 ,  C07K14/535 ,  C12M1/40 ,  C12M1/00 ,  C12M1/36 ,  C12M3/00 ,  B01D15/12 ,  B01D15/10 ,  B01D15/14 ,  B01D15/22 ,  B01D15/38 ,  B01D15/34 ,  B01D15/36 ,  C12N9/12

    CPC classification number: B01D15/361 ,  B01D15/10 ,  B01D15/12 ,  B01D15/14 ,  B01D15/22 ,  B01D15/34 ,  B01D15/3804 ,  C07K14/505 ,  C07K14/535 ,  C12M21/18 ,  C12M23/28 ,  C12M23/44 ,  C12M29/00 ,  C12M41/48 ,  C12M47/10 ,  C12N9/1223 ,  C12N9/1252 ,  C12P21/02 ,  C12Y207/03002 ,  C12Y207/07007

    Abstract: A portable fluidic platform for rapid and flexible end-to-end production of recombinant protein biologics includes a bioreactor system hosting stable and robust cell-free translation systems that is fluidically integrated with modular protein separation functionalities (e.g., size exclusion, ion exchange or affinity chromatography systems) for purification of the cell-free expressed product and which are configurable for process-specific isolation of different proteins, as well as for formulation. The bioreactor utilizes lysates from engineered eukaryotic (e.g., yeast) or prokaryotic (e.g., bacterial) strains that contain factors for protein folding and posttranslational modifications. Combination of various purification modules on the same fluidic platform allows flexibility of re-routing for purification of different proteins depending on specific target requirements. Protein synthesis and purification modules are integrated into self-contained disposable fluidic cartridge that eliminates cross-contamination between runs. The platform allows for flexible production of protein biologics within 24 hours (from DNA to purified product).

    Abstract translation: 用于重组蛋白质生物制剂的快速和灵活的端到端生产的便携式流体平台包括一个生物反应器系统，其承载稳定且稳健的无细胞翻译系统，其与模块化蛋白质分离功能（例如尺寸排阻，离子交换或亲和力 色谱系统），用于纯化无细胞表达产物，并且其可配置用于不同蛋白质的过程特异性分离，以及用于制剂。 生物反应器利用来自工程真核（例如酵母）或原核（例如细菌）菌株的裂解物，其含有蛋白质折叠和翻译后修饰的因子。 在同一流体平台上组合各种纯化模块，可根据具体目标要求灵活地进行不同蛋白质的纯化。 蛋白质合成和纯化模块集成到独立的一次性流体盒中，消除了运行之间的交叉污染。 该平台允许在24小时内灵活地生产蛋白质生物制品（从DNA到纯化的产品）。

    System and method for fusing chemical detectors
    187.
    发明授权
    System and method for fusing chemical detectors 有权
    化学检测器的系统和方法

    公开(公告)号：US09390898B1

    公开(公告)日：2016-07-12

    申请号：US14474559

    申请日：2014-09-02

    Applicant: Leidos, Inc.

    Inventor： Charles Stephen Harden ,  Robert James Schafer

    IPC: H01J49/00 ,  H01J49/02 ,  G01N27/62 ,  H01J49/40

    CPC classification number: G01N27/622 ,  G01N27/624 ,  H01J49/0013 ,  H01J49/0022 ,  H01J49/004 ,  H01J49/009 ,  H01J49/0095

    Abstract: Two complementary approaches to the science of IMS technology, IMS and differential IMS (DIMS), are combined into a single instrument to provide improvements in interference rejection without sacrificing detection sensitivity. The technology is applicable to, inter alia, the analysis of trace quantities of toxic or otherwise dangerous organic chemical materials. The approach improves both sensitivity and specificity (interference rejection) of field detection instrumentation.

    Abstract translation: 将IMS技术，IMS和差分IMS（DIMS）的科学技术的两种互补方法组合成一个单一的仪器，以提供干扰抑制的改进，而不会牺牲检测灵敏度。 该技术特别适用于痕量有毒或其他危险的有机化学材料的分析。 该方法提高了现场检测仪器的灵敏度和特异性（干扰抑制）。

    Switching Frequency Extended Range Geiger Detection System and Method
    188.
    发明申请
    Switching Frequency Extended Range Geiger Detection System and Method 有权
    开关频率扩展范围盖革检测系统及方法

    公开(公告)号：US20160178760A1

    公开(公告)日：2016-06-23

    申请号：US15040384

    申请日：2016-02-10

    Applicant: Leidos, Inc.

    Inventor： Eric Matthew AMENDT ,  Ryan SHYFFER

    IPC: G01T1/18 ,  H03B5/20 ,  H03B5/32

    CPC classification number: G01T1/18 ,  H03B5/20 ,  H03B5/32

    Abstract: A Geiger-Mueller charge particle rate measurement system includes a clock management unit in combination with multiple oscillators and rate feedback controller to allow for reactive switching between the different oscillator frequencies to optimize system use. Controlling the clock management unit to send the appropriate frequency (clock signal) to the timers in response to measured rate date from the rate feedback controller facilitates operation at different clock speeds, which helps reduce power consumption when operated at lower speeds.

    Abstract translation: Geiger-Mueller电荷粒子速率测量系统包括与多个振荡器和速率反馈控制器相结合的时钟管理单元，以允许不同振荡器频率之间的无功切换以优化系统使用。 控制时钟管理单元根据速率反馈控制器测量的速率日期向定时器发送适当的频率（时钟信号）便于在不同时钟速度下运行，这有助于在较低速度下运行时降低功耗。

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