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    Bent PCB Ion Guide for Reduction of Contamination and Noise
    11.
    发明公开
    Bent PCB Ion Guide for Reduction of Contamination and Noise 审中-公开

    公开(公告)号：US20240290600A1

    公开(公告)日：2024-08-29

    申请号：US18278544

    申请日：2022-02-23

    Applicant: DH Technologies Development Pte. Ltd.

    Inventor： Aaron Timothy BOOY ,  James HAGER

    IPC: H01J49/06

    CPC classification number: H01J49/062

    Abstract: In one aspect, an ion guide for use in a mass spectrometer is disclosed, which comprises a first plurality of conductive electrodes disposed on a first surface, a second plurality of conductive electrodes disposed on a second surface, wherein the two surfaces are positioned relative to one another and shaped so as to provide a passageway having an inlet for receiving an ion beam and an outlet through which target ions of interest exit the passageway. The ion guide further includes an orifice formed in at least one of those surfaces through which neutral species and/or large ion clusters, when present in the ion beam, exit the ion guide.

    Low noise bipolar high voltage regulator
    12.
    发明授权
    Low noise bipolar high voltage regulator 有权

    公开(公告)号：US12072725B2

    公开(公告)日：2024-08-27

    申请号：US17762244

    申请日：2020-09-24

    Applicant: DH Technologies Development PTE. LTD.

    Inventor： Manuel Faur ,  Ernesto Gradin

    IPC: G05F1/595 ,  G05F1/575

    CPC classification number: G05F1/595 ,  G05F1/575

    Abstract: In one aspect, a voltage regulator is disclosed, which comprises a first voltage regulator unit configured for regulating a voltage generated by a positive high voltage source, a second voltage regulator unit configured for regulating a voltage generated by a negative high voltage source, a polarity switch for connecting said first and second voltage regulator units to said positive and negative high voltage sources, respectively, and an output voltage port for receiving a regulated positive and negative high voltage from said first and said second voltage regulator units, respectively.

    Apparatus and methods for reduced neutral contamination in a mass spectrometer
    17.
    发明授权
    Apparatus and methods for reduced neutral contamination in a mass spectrometer 有权

    公开(公告)号：US12002672B2

    公开(公告)日：2024-06-04

    申请号：US16630007

    申请日：2018-06-29

    Applicant: DH Technologies Development Pte. Ltd.

    Inventor： Bruce Collings ,  Pascal Martin

    IPC: H01J49/00 ,  H01J49/06 ,  H01J49/42

    CPC classification number: H01J49/067 ,  H01J49/0031 ,  H01J49/4225 ,  H01J49/426

    Abstract: Apparatus and methods for controlling contamination of components contained within the high-vacuum chambers of mass spectrometer systems are provided. The apparatus and methods employ a beam of neutral gas injected in a contra-flow configuration to incoming particle stream from the ionization chamber. The contra-flow can be in the directly opposite counter-flow direction (e.g., 180 degrees) or at a cross-flow angle to the incoming ion stream (e.g., flowing at an angle between about 10 degrees and 170 degrees). The contra-flow disrupts the axial gas flow and diverts neutral molecules and other undesirable contaminants before they reach the high vacuum stages (e.g., beyond the IQ0 orifice) of the spectrometer. By reducing the transmission of contaminants into the sensitive components housed deep within the mass spectrometer, the present invention can increase throughput, improve robustness, and/or decrease the downtime typically required to vent/disassemble/clean the fouled components.

    Flow Module Selector
    18.
    发明公开
    Flow Module Selector 审中-公开

    公开(公告)号：US20240175849A1

    公开(公告)日：2024-05-30

    申请号：US18281277

    申请日：2022-03-11

    Applicant: DH Technologies Development Pte. Ltd.

    Inventor： Ravi IYER ,  Andrew KUCHER ,  David NEYER ,  Randy ROUSHALL ,  Remco VAN SOEST ,  Hao YANG

    IPC: G01N30/32 ,  G01N30/02 ,  G01N30/72

    CPC classification number: G01N30/32 ,  G01N30/7233 ,  G01N2030/027 ,  G01N2030/324 ,  G01N2030/326 ,  G01N2030/328

    Abstract: In one aspect, a system for adjusting flow rate of at least one mobile phase delivered to a liquid chromatography (LC) column is disclosed, which includes a first plurality of pre-calibrated flow modules each configured to receive a first mobile phase at an inlet port thereof and to provide a pre-calibrated range of output flow rates of said first mobile phase at its outlet port, wherein said first plurality of flow modules are configured to provide different ranges of output flow rates of said first mobile phase, and a first selector valve in fluid communication with said first plurality of pre-calibrated flow modules for selecting among said first plurality of pre-calibrated flow modules for selective delivery of said first mobile phase to said LC column, thereby adjusting the flow rate of the first mobile phase delivered to said LC column.

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