公开(公告)号：US20100280363A1

公开(公告)日：2010-11-04

申请号：US12767163

申请日：2010-04-26

Applicant: James Skarda ,  Mark Stewart ,  James Keogh ,  David Francischelli ,  Kenneth C. Gardeski ,  Thomas A. Poss ,  Michael Neidert

Inventor： James Skarda ,  Mark Stewart ,  James Keogh ,  David Francischelli ,  Kenneth C. Gardeski ,  Thomas A. Poss ,  Michael Neidert

IPC: A61B5/05

CPC classification number: A61B1/00154 ,  A61B1/00135 ,  A61B34/20 ,  A61B90/361 ,  A61B2017/00243 ,  A61B2017/00336 ,  A61B2034/2051 ,  A61N1/056

Abstract: The present invention provides devices, instruments, systems, and methods to navigate medical instruments within the thoracic cavity. More specifically, the present invention provides a navigation system comprising medical instruments having electromagnetic tracking functionality and the integration of previously acquired imaging into a user interface of the navigation system.

Abstract translation: 本发明提供了用于在胸腔内导航医疗器械的装置，仪器，系统和方法。 更具体地，本发明提供了一种导航系统，其包括具有电磁跟踪功能的医疗仪器和将先前获取的成像集成到导航系统的用户界面中。

公开(公告)号：US20090142736A1

公开(公告)日：2009-06-04

申请号：US12274943

申请日：2008-11-20

Applicant: Eren Tolga Rosenfeld ,  Ekpedeme Mfon Bassey ,  Beth Elyse Zadik ,  Martha Torrey O'Connor ,  Alexander Han Leung Poon ,  Eric Jeffrey Lannert ,  Tracey Andrea Solomon ,  Jonathan Christian Conant ,  Alexander Zorba ,  Carl Michael Puccio ,  Timothy John Gobran ,  James Andrew Gilchrist ,  Mark Stewart Nichols ,  Brandon Denning Fleisher ,  Craig William Friedman ,  Adebisi Detoro Lipede ,  Matthew Allen Bailey

Inventor： Eren Tolga Rosenfeld ,  Ekpedeme Mfon Bassey ,  Beth Elyse Zadik ,  Martha Torrey O'Connor ,  Alexander Han Leung Poon ,  Eric Jeffrey Lannert ,  Tracey Andrea Solomon ,  Jonathan Christian Conant ,  Alexander Zorba ,  Carl Michael Puccio ,  Timothy John Gobran ,  James Andrew Gilchrist ,  Mark Stewart Nichols ,  Brandon Denning Fleisher ,  Craig William Friedman ,  Adebisi Detoro Lipede ,  Matthew Allen Bailey

IPC: G09B19/00 ,  G06N5/02 ,  G09B7/00 ,  G06F17/00

CPC classification number: G09B7/04 ,  Y10S706/927

Abstract: A system is disclosed that provides a goal based learning system utilizing a rule based expert training system to provide a cognitive educational experience. The system provides the user with a simulated environment that presents a business opportunity to understand and solve optimally. Mistakes are noted and remedial educational material presented dynamically to build the necessary skills that a user requires for success in the business endeavor. The system utilizes an artificial intelligence engine driving individualized and dynamic feedback with synchronized video and graphics used to simulate real-world environment and interactions. A robust business model provides support for realistic activities and allows a user to experience real world consequences for their actions and decisions and entails realtime decision-making and synthesis of the educational material. The system is architectured around a table of components to manage and control the system.

Abstract translation: 公开了一种系统，其提供基于目标的学习系统，其利用基于规则的专家训练系统来提供认知教育经验。 该系统为用户提供了一个模拟环境，为您提供了理解和最佳解决方案的商机。 注意到错误，并动态呈现补救性教材，以建立用户在业务活动中获得成功所需的必要技能。 该系统利用人造智能引擎，驱动具有同步视频和图形的个性化和动态反馈，用于模拟现实环境和交互。 强大的商业模式提供对现实活动的支持，并允许用户体验现实世界对他们的行为和决策的后果，并需要实时决策和综合教材。 系统围绕组件表构建，以管理和控制系统。

公开(公告)号：US20080275439A1

公开(公告)日：2008-11-06

申请号：US12055991

申请日：2008-03-26

Applicant: David Francischelli ,  Mark Stewart ,  Daniel Cheek ,  Brian Ross ,  Paul Rothstein ,  Scott Klein ,  Asif Hameed ,  Doug Crowe ,  Kester Batchelor ,  William Colon

Inventor： David Francischelli ,  Mark Stewart ,  Daniel Cheek ,  Brian Ross ,  Paul Rothstein ,  Scott Klein ,  Asif Hameed ,  Doug Crowe ,  Kester Batchelor ,  William Colon

IPC: A61B18/12

CPC classification number: A61B18/1402 ,  A61B5/0422 ,  A61B18/1492 ,  A61B2017/00053 ,  A61B2018/00357 ,  A61B2018/00363 ,  A61B2018/00577 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1472 ,  A61N1/06 ,  A61N1/36017

Abstract: A system for ablating tissue and electrically interfacing with a heart including an electrosurgical instrument, an energy source, and a controller. The instrument includes a shaft maintaining first and second electrodes at a distal section. The electrodes are electrically isolated from one another. The controller controls delivery of energy from the energy source, and monitors electrical signals at the electrodes. The controller is programmed to operate in a monopolar mode and a bipolar mode. In the monopolar mode, the first and second electrodes are electrically uncoupled, and energy from the energy source is delivered to the first electrode in performing an ablation procedure. In the bipolar mode, first and second electrodes are electrically coupled and serve as opposite polarity poles to apply energy to a tissue target site, detect electrical signals at a tissue target site, or both.

Abstract translation: 一种用于消融组织并与包括电外科器械，能量源和控制器的心脏电接口的系统。 仪器包括轴，其在远端部分保持第一和第二电极。 电极彼此电隔离。 控制器控制能量从能源的传递，并监测电极处的电信号。 控制器被编程为在单极模式和双极模式下工作。 在单极模式中，第一和第二电极是电耦合的，并且来自能量源的能量在执行消融过程时被传送到第一电极。 在双极模式中，第一和第二电极被电耦合并且用作相反的极性极以将能量施加到组织靶位点，检测组织靶位置处的电信号，或者两者。

公开(公告)号：US20080128996A1

公开(公告)日：2008-06-05

申请号：US12010801

申请日：2008-01-30

Applicant: Christopher Grace ,  Mark Stewart Schroder ,  Paul Stephen Dimascio

Inventor： Christopher Grace ,  Mark Stewart Schroder ,  Paul Stephen Dimascio

IPC: F16J15/44

CPC classification number: F16J15/3288

Abstract: A silicon carbide fiber brush seal, suitable for use with SiC—SiC CMC components. The seal may be coated with a boron nitride based coating.

Abstract translation: 碳化硅纤维刷密封，适用于SiC-SiC CMC组件。 密封件可以涂覆有氮化硼基涂层。

公开(公告)号：US20080033457A1

公开(公告)日：2008-02-07

申请号：US11788261

申请日：2007-04-19

Applicant: David Francischelli ,  Roderick Briscoe ,  Leonard Leuer ,  Daniel Haeg ,  Tom Daigle ,  David Kim ,  Mark Stewart ,  Andrew Olson ,  Patrick Cloutier ,  Christopher Smith ,  Michael Hobday ,  Tessy Kanayinkal ,  Douglas Gubbin ,  Paul Rothstein ,  Joseph Cardinal ,  Jessica Foley ,  Christopher Plott

Inventor： David Francischelli ,  Roderick Briscoe ,  Leonard Leuer ,  Daniel Haeg ,  Tom Daigle ,  David Kim ,  Mark Stewart ,  Andrew Olson ,  Patrick Cloutier ,  Christopher Smith ,  Michael Hobday ,  Tessy Kanayinkal ,  Douglas Gubbin ,  Paul Rothstein ,  Joseph Cardinal ,  Jessica Foley ,  Christopher Plott

IPC: A61B17/122

CPC classification number: A61B17/12 ,  A61B17/0057 ,  A61B17/12009 ,  A61B17/12013 ,  A61B17/122 ,  A61B17/128 ,  A61B17/1285 ,  A61B90/39 ,  A61B2017/00243 ,  A61B2017/00575 ,  A61B2017/12018 ,  A61B2017/306

Abstract: Some embodiments of the invention provide a system for occluding a left atrial appendage of a patient. Some embodiments of the system can include a ring occluder that can be positioned around the left atrial appendage and a ring applicator to position the ring occluder with respect to the left atrial appendage. One embodiment discloses a method of accessing endocardial surfaces of the heart through the atrial appendage. Additional embodiments of the invention provide a clip occluder that can be positioned around the left atrial appendage. A clip applicator can position the clip occluder with respect to the left atrial appendage.

Abstract translation: 本发明的一些实施例提供一种用于闭塞患者左心耳的系统。 该系统的一些实施例可以包括可以围绕左心耳定位的环封闭器和环施加器来相对于左心耳定位环封闭器。 一个实施例公开了通过心房接近心脏心脏表面的方法。 本发明的另外的实施例提供了可以围绕左心耳定位的夹子封堵器。 夹子施放器可以相对于左心耳定位夹子封堵器。

公开(公告)号：US20080021142A1

公开(公告)日：2008-01-24

申请号：US11843275

申请日：2007-08-22

Applicant: Mark Stewart ,  Emerson Sharpe ,  Benjamin Gamble ,  Steven Stafford ,  Robert Estep ,  James Williams ,  Thomas Clark

Inventor： Mark Stewart ,  Emerson Sharpe ,  Benjamin Gamble ,  Steven Stafford ,  Robert Estep ,  James Williams ,  Thomas Clark

IPC: C08K5/098 ,  C08K3/10 ,  C08K3/22 ,  C08K3/28 ,  C08K3/30 ,  C08K3/32 ,  C08K3/34 ,  C08K3/38

CPC classification number: C08K5/098 ,  C08L67/02 ,  C08L77/00 ,  Y10T428/1352 ,  Y10T428/1383 ,  C08L2666/14

Abstract: A solid concentrate is provided having a combination of a transition metal present in an amount ranging from 1000 to 40,000 ppm (weight by metal) and a polyester polymer present in an amount of at least 40 wt. % based on the weight of the concentrate. Concentrates made with highly modified polyester polymers are easy to compound with transition metals forming less brittle polymer upon melt extrusion. Bottle preforms and oxygen scavenging bottles can be made from these concentrates by combining solid polyester particles, solid polyamide particles, and solid these concentrate particles c into an melt processing zone, forming a melt, and forming an article directly from the melt. The b* color and the L* color and the haze levels of the preforms are improved over the preforms made with liquid carriers instead of solid concentrates. The particles are also advantageously simultaneously dried in a drying zone under conditions effective to at least partially remove moisture from the blend to thereby further improve the b* color and L* color.

Abstract translation: 提供了一种固体浓缩物，其具有的存在量为1000至40,000ppm（金属重量）的过渡金属和以至少40重量％的量存在的聚酯聚合物的组合。 基于浓缩物的重量％。 用高度改性的聚酯聚合物制成的浓缩物易于与熔融挤出时形成较少脆性聚合物的过渡金属复合。 通过将固体聚酯颗粒，固体聚酰胺颗粒和固体这些浓缩颗粒c结合到熔融加工区域中，形成熔体并从熔体直接形成制品，可以从这些浓缩物制备瓶预成型件和除氧瓶。 相对于用液体载体代替固体浓缩物制成的预成型件，预型件的b *颜色和L *颜色和雾度水平得到改善。 在有效地至少部分地从共混物中除去水分的条件下，还可以在干燥区中同时干燥颗粒，从而进一步改善b *颜色和L *颜色。

公开(公告)号：US20070219550A1

公开(公告)日：2007-09-20

申请号：US11698807

申请日：2007-01-26

Applicant: Mark Thompson ,  Darrin Dickerson ,  Brett Bowman ,  Christopher Kelly ,  William Malecki ,  David Francischelli ,  Mark Stewart ,  Thomas Daigle ,  Douglas Gubbin ,  David Kim ,  Paul Rothstein ,  Adam Podbelski ,  Christopher Plott ,  Benjamin Yaffe

Inventor： Mark Thompson ,  Darrin Dickerson ,  Brett Bowman ,  Christopher Kelly ,  William Malecki ,  David Francischelli ,  Mark Stewart ,  Thomas Daigle ,  Douglas Gubbin ,  David Kim ,  Paul Rothstein ,  Adam Podbelski ,  Christopher Plott ,  Benjamin Yaffe

IPC: A61B18/18

CPC classification number: A61B17/00234 ,  A61B1/0055 ,  A61B17/0218 ,  A61B18/1482 ,  A61B90/30 ,  A61B2017/003 ,  A61B2017/00367 ,  A61B2017/320044 ,  A61B2090/0811

Abstract: A device for dissecting tissue and/or guidance of a second device to a desired physiological location, the device comprising: an elongate shaft comprising a proximal portion and a distal portion, wherein the distal portion comprises a plurality of segments that articulate with respect to one another; and a handle attached to the proximal portion of the shaft, wherein the handle comprises controls for articulating the plurality of segments of the distal portion of the shaft with respect to one another. A system for dissecting tissue and/or guiding a medical device to a desired physiological location.

Abstract translation: 一种用于将第二装置的组织和/或引导解剖到期望的生理位置的装置，所述装置包括：细长轴，其包括近端部分和远侧部分，其中所述远端部分包括多个相对于一个 另一个; 以及附接到所述轴的近侧部分的手柄，其中所述手柄包括用于相对于彼此铰接所述轴的远侧部分的所述多个段的控制。 一种用于将组织切割和/或将医疗装置引导到所需生理位置的系统。

公开(公告)号：US07194444B1

公开(公告)日：2007-03-20

申请号：US09868752

申请日：1999-02-08

Applicant: Mark Stewart Nichols

Inventor： Mark Stewart Nichols

IPC: G06F17/00 ,  G06F17/20 ,  G09B19/00 ,  G09B3/00 ,  G09B7/00 ,  G06N5/02

CPC classification number: G09B5/00 ,  Y10S706/927 ,  Y10S706/934

Abstract: A system is disclosed that provides a goal based learning system utilizing a rule based expert training system to provide a cognitive educational experience. The system provides the user with a simulated environment that presents a business opportunity to understand and solve optimally. Mistakes are noted and remedial educational material presented dynamically to build the necessary skills that a user requires for success in the business endeavor. The system utilizes an artificial intelligence engine driving individualized and dynamic feedback with synchronized video and graphics used to simulate real-world environment and interactions. Multiple “correct” answers are integrated into the learning system to allow individualized learning experiences in which navigation through the system is at a pace controlled by the learner. A robust business model provides support for realistic activities and allows a user to experience real world consequences for their actions and decisions and entails realtime decision-making and synthesis of the educational material. The system provides student controls that guide a student through a presentation in a manner designed to optimize the learning experience.

Abstract translation: 公开了一种系统，其提供基于目标的学习系统，其利用基于规则的专家训练系统来提供认知教育经验。 该系统为用户提供了一个模拟环境，为您提供了理解和最佳解决方案的商机。 注意到错误，并动态呈现补救性教材，以建立用户在业务活动中获得成功所需的必要技能。 该系统利用人造智能引擎，驱动具有同步视频和图形的个性化和动态反馈，用于模拟现实环境和交互。 将多个“正确”答案整合到学习系统中，以允许个人化的学习体验，其中通过系统的导航处于学习者控制的步伐。 强大的商业模式提供对现实活动的支持，并允许用户体验现实世界对他们的行为和决策的后果，并需要实时决策和综合教材。 该系统提供学生控制，指导学生通过演示，以优化学习体验。

公开(公告)号：US20060199904A1

公开(公告)日：2006-09-07

申请号：US11363374

申请日：2006-02-27

Applicant: Wesley Hale ,  Thomas Pecorini ,  Mark Stewart ,  Martin Rogers ,  Spencer Gilliam ,  Michael Cliffton

Inventor： Wesley Hale ,  Thomas Pecorini ,  Mark Stewart ,  Martin Rogers ,  Spencer Gilliam ,  Michael Cliffton

IPC: C08L77/00 ,  C08G69/48 ,  C08L69/00

CPC classification number: C08L69/00 ,  B32B27/08 ,  B32B27/18 ,  B32B27/34 ,  B32B27/36 ,  B32B27/365 ,  B32B2250/24 ,  B32B2264/105 ,  B32B2270/00 ,  B32B2307/412 ,  B32B2307/738 ,  B32B2307/74 ,  B32B2439/60 ,  C08K3/08 ,  C08L67/00 ,  C08L67/02 ,  C08L77/00 ,  C08L2205/02 ,  C08L2205/03 ,  Y10T428/13 ,  Y10T428/1334 ,  Y10T428/1352 ,  Y10T428/1355 ,  Y10T428/1359 ,  Y10T428/1379 ,  Y10T428/1383 ,  Y10T428/31725 ,  Y10T428/31736 ,  Y10T428/31739 ,  C08L2666/20 ,  C08L2666/14 ,  C08L2666/18

Abstract: Disclosed are oxygen-scavenging polymer compositions having high transparency and low haze comprising immiscible blends of one or more thermoplastic polymers selected from polyesters, polycarbonates, and polyarylates, a copolyamide or a transamidized, homogeneous blend of a least two polyamides, and a metal catalyst. The components of the immiscible blend which have refractive indices which differ by about 0.006 to about −0.0006. The small difference in the refractive indices enable the incorporation of regrind into the polymer composition to produce transparent shaped articles. The blends of the present invention are useful in producing shaped articles such as, for example, sheeting, films, tubes, bottles, preforms and profiles. These articles may have one or more layers and can exhibit improved excellent barrier properties and good melt processability while retaining excellent mechanical properties.

Abstract translation: 公开了具有高透明度和低雾度的除氧聚合物组合物，其包含选自聚酯，聚碳酸酯和聚芳酯的一种或多种热塑性聚合物的不混溶的共混物，至少两种聚酰胺的共聚酰胺或酰胺化的均匀共混物和金属催化剂。 不混溶共混物的组分具有约0.006至约-0.0006的折射率。 折射率的小差异使得能够将再研磨物掺入聚合物组合物中以产生透明成型制品。 本发明的共混物可用于生产成形制品，例如片材，薄膜，管，瓶，预型件和型材。 这些制品可以具有一层或多层，并且可以表现出改进的优异的阻隔性能和良好的熔融加工性，同时保持优异的机械性能。

公开(公告)号：US20060197246A1

公开(公告)日：2006-09-07

申请号：US11363417

申请日：2006-02-27

Applicant: Wesley Hale ,  Thomas Pecorini ,  Mark Stewart ,  Martin Rogers ,  Spencer Gilliam ,  Michael Cliffton

Inventor： Wesley Hale ,  Thomas Pecorini ,  Mark Stewart ,  Martin Rogers ,  Spencer Gilliam ,  Michael Cliffton

IPC: B29B17/00

CPC classification number: B29B17/0042 ,  C08K3/08 ,  C08L67/00 ,  C08L67/02 ,  C08L69/00 ,  C08L77/00 ,  C08L2205/02 ,  Y02W30/62 ,  Y10T428/13 ,  Y10T428/1334 ,  Y10T428/1352 ,  Y10T428/1355 ,  Y10T428/1359 ,  Y10T428/1379 ,  Y10T428/1383 ,  Y10T428/31725 ,  Y10T428/31736 ,  Y10T428/31739 ,  C08L2666/20 ,  C08L2666/14

Abstract: Disclosed is a process for the preparation of shaped articles such as, for example, sheeting, films, tubes, bottles, preforms and profiles, having high transparency and low haze comprising immiscible blends of one or more thermoplastic polymers selected from polyesters, polycarbonates, and polyarylates, and a copolyamide or a transamidized, homogeneous blend of a least two polyamides. The components of the immiscible blend which have refractive indices which differ by about 0.006 to about −0.0006. The small difference in the refractive indices enable the incorporation of regrind into the polymer composition to produce transparent shaped articles. These articles may have one or more layers and can exhibit improved excellent barrier properties and good melt processability while retaining excellent mechanical properties. Metal catalysts can be incorporated into the compositions to produce shaped articles having oxygen-scavenging properties.

Abstract translation: 公开了一种制备成形制品的方法，例如片材，膜，管，瓶，预成型件和型材，具有高透明度和低雾度，包括一种或多种选自聚酯，聚碳酸酯和/或其中的热塑性聚合物的不混溶共混物 聚芳酯，以及至少两种聚酰胺的共聚酰胺或酰胺化的均匀共混物。 不混溶共混物的组分具有约0.006至约-0.0006的折射率。 折射率的小差异使得能够将再研磨物掺入聚合物组合物中以产生透明成型制品。 这些制品可以具有一层或多层，并且可以表现出改进的优异的阻隔性能和良好的熔融加工性，同时保持优异的机械性能。 可以将金属催化剂引入到组合物中以产生具有除氧性能的成形制品。