公开(公告)号：US20180305726A1

公开(公告)日：2018-10-25

申请号：US15769964

申请日：2016-10-21

Applicant: AMOREPACIFIC CORPORATION

Inventor： Gi Baeg NAM ,  Dong Hyun KIM ,  Yong Deog HONG ,  Jun Seong PARK ,  Kyoung Hee BYOUN

IPC: C12P33/00

CPC classification number: C12P33/00 ,  C07H17/00 ,  C07J17/00 ,  C12N9/24 ,  C12P19/14 ,  C12P19/44 ,  C12P33/16 ,  C12Y302/01006 ,  C12Y302/01015

Abstract: The present invention relates to a method for selectively producing ginsenoside F2, compound Mc or compound O, which is originally present in ginseng in a trace amount, from a saponin of ginseng, and more specifically to a method capable of obtaining desired target compounds, that is, ginsenoside F2, compound Mc and compound O, in high yields, by treating saponins, obtained from ginseng, with particular enzymes to structurally convert the saponins.

公开(公告)号：US20180303737A1

公开(公告)日：2018-10-25

申请号：US15764625

申请日：2016-09-29

Applicant: AMOREPACIFIC CORPORATION

Inventor： Young Gyu KANG ,  Jae Young KO ,  Jun Seong PARK

IPC: A61K8/60 ,  A61Q7/00

CPC classification number: A61K8/60 ,  A61K8/02 ,  A61K8/63 ,  A61K8/97 ,  A61Q7/00 ,  A61Q19/00

Abstract: The present invention relates to a composition for improving scalp condition and/or promoting hair restoration containing soyasaponin or a derivative thereof, which can be widely used as an external skin preparation for improving scalp condition and/or promoting hair growth and hair restoration, a cosmetic composition or a pharmaceutical composition, as the composition has high stability for skin without side effects, improves a scalp condition, and is effective in promoting hair growth and/or preventing hair loss by activating stem cells.

公开(公告)号：US20180078482A1

公开(公告)日：2018-03-22

申请号：US15561560

申请日：2016-03-25

Applicant: AMOREPACIFIC CORPORATION

Inventor： Yong Deog HONG ,  Jae Young KO ,  Jun Seong PARK

IPC: A61K8/63 ,  A61K31/56 ,  A61Q19/08 ,  A61Q5/02 ,  A61Q19/10 ,  A61K36/82 ,  A61K8/9789 ,  A23L33/105 ,  A23L2/52

CPC classification number: A61K8/63 ,  A23L2/52 ,  A23L33/105 ,  A23V2002/00 ,  A61K8/0225 ,  A61K8/9789 ,  A61K9/0014 ,  A61K9/0095 ,  A61K9/06 ,  A61K9/1623 ,  A61K9/2018 ,  A61K9/4875 ,  A61K31/225 ,  A61K31/56 ,  A61K36/82 ,  A61K47/10 ,  A61K2800/92 ,  A61P17/10 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q19/00 ,  A61Q19/008 ,  A61Q19/08 ,  A61Q19/10 ,  A23V2200/318 ,  A23V2250/21

Abstract: The present specification discloses a composition for shrinking pores, inhibiting or improving wrinkles, promoting skin elasticity, regulating sebum, and preventing or improving acne skin, the composition containing, as an active ingredient, theasapogenol derivative 21-O-angeloyltheasapogenol E3 as one embodiment.

公开(公告)号：US20170135948A1

公开(公告)日：2017-05-18

申请号：US15320012

申请日：2015-06-18

Applicant: AMOREPACIFIC CORPORATION

Inventor： Young Gyu KANG ,  Ok Chan LEE ,  Yong Deog HONG ,  Myeong Hun YEOM ,  Jun Seong PARK

IPC: A61K8/97 ,  A61Q19/00 ,  A61K36/48 ,  A61K9/00 ,  A23L33/105 ,  A61K9/20 ,  A61K9/14 ,  A61K9/06 ,  A23L2/52 ,  A61Q19/08 ,  A61K9/48

CPC classification number: A61K8/97 ,  A23L2/52 ,  A23L33/105 ,  A23V2002/00 ,  A61K8/9783 ,  A61K9/0014 ,  A61K9/0019 ,  A61K9/06 ,  A61K9/14 ,  A61K9/20 ,  A61K9/48 ,  A61K36/48 ,  A61Q19/00 ,  A61Q19/007 ,  A61Q19/08

Abstract: The present specification relates to a composition for a skin preparation for external use, containing an extract of bean leaves (danpung bean leaves) of a specific stage among the growth stages of beans as an active ingredient. The composition according to the present invention has an excellent antioxidant property, an excellent antiaging property and no skin irritation since natural-derived ingredients are contained in the composition, and thus is useful. The composition of the present specification can be widely used, by such characteristics, as an antioxidant or antiaging composition of an individual in the pharmaceutical or cosmetic field.

公开(公告)号：US20160220622A1

公开(公告)日：2016-08-04

申请号：US15093089

申请日：2016-04-07

Applicant: AMOREPACIFIC CORPORATION

Inventor： Jun Seong PARK ,  Hye Yoon PARK ,  Dong Hyun KIM ,  Eun Jeong MOON ,  Ji Hye CHUNG ,  Jae Kyoung LEE ,  Duck Hee KIM ,  Han Kon KIM

IPC: A61K36/185

CPC classification number: A61K36/185 ,  A23L33/105 ,  A23V2002/00 ,  A61K36/232 ,  A61K36/28 ,  A61K36/287 ,  A61K36/428 ,  A61K36/45 ,  A61K36/732 ,  A61K36/78 ,  A61K36/8945

Abstract: The present invention relates to an extract of a processed herbal medicinal plant and a composition for skin external application which contains the extract. More specifically, the composition for skin external application contains an extract of processed herbal medicinal plant, prepared through a method comprising the steps of: (a) processing an herbal medicinal plant by a process of boiling, steaming, roasting, baking or heating the medicinal plant or a combination of two or more of these processes; (b) obtaining an extract of the processed medicinal plant. The composition shows an improved antioxidant effect.

Abstract translation: 本发明涉及含有该提取物的加工草药植物提取物和皮肤外用组合物。 更具体地，皮肤外用组合物含有通过包括以下步骤的方法制备的加工草药植物提取物：（a）通过沸腾，蒸煮，焙烧，烘烤或加热药物的方法加工中草药植物 植物或两种或更多种这些方法的组合; （b）获得加工药用植物的提取物。 该组合物显示出改进的抗氧化作用。

公开(公告)号：US20200261351A1

公开(公告)日：2020-08-20

申请号：US16651878

申请日：2018-08-23

Applicant: AMOREPACIFIC CORPORATION

Inventor： Hyoung-June KIM ,  Kyeonghwan HWANG ,  Jun Seong PARK ,  Tae Ryong LEE

IPC: A61K8/9789 ,  A61K36/82 ,  A23L33/105 ,  A61Q19/08

Abstract: The present specification discloses a composition for caring for skin damage caused by fine dust, wherein the composition includes a fermented tea extract as an active ingredient and adjusts the expression level of at least one selected from the following group of genes which are present in skin cells and have expression levels that are affected by fine dust to normal levels, said group consisting of: IL-1B (NM_000576), IL-36G (NM_019618), S100A7 (NM_002963), LCE3D (NM_032563), PTGS2 (NM_000963) and XDH (NM_000379). Damage to skin cells can be cared for by using the composition for caring for skin damage caused by fine dust to return gene expression levels, which change due to fine dust, to normal levels.

公开(公告)号：US20200030225A1

公开(公告)日：2020-01-30

申请号：US16338226

申请日：2017-09-21

Applicant: AMOREPACIFIC CORPORATION

Inventor： Yeong Ran LEE ,  Jun Seong PARK ,  Eun Soo LEE ,  Nok Hyun PARK

IPC: A61K8/9789 ,  A61Q19/10 ,  A61Q19/00 ,  A61Q19/08 ,  A61Q17/00 ,  A61K36/82

Abstract: The present invention relates to a skin external composition containing an extract of green tea produced by an extreme light-shielding cultivation method, which is distinguished from a conventional light-shielding cultivation method of green tea. More specifically, the present invention relates to a skin external composition, which contains an extract of green tea cultivated by extreme light-shielding, in which the amino acid content is remarkably increased by cultivating the green tea by a light-shielding cultivation under a light-shielding rate of 99% or more, thereby obtaining more excellent skin moisturizing, skin protecting, and anti-aging effects.

公开(公告)号：US20190142721A1

公开(公告)日：2019-05-16

申请号：US16241414

申请日：2019-01-07

Applicant: AMOREPACIFIC CORPORATION

Inventor： Yong Deog HONG ,  Kyum Son KIM ,  Jun Seong PARK ,  Sang Hoon HAN

IPC: A61K8/49 ,  A61Q19/00 ,  G01N33/50 ,  G01N33/80 ,  A61Q19/08 ,  A61K8/37

Abstract: A composition containing a material for regulating the expression of ABH antigens and, more specifically, to a composition capable of: controlling sebum production and alleviating skin trouble by regulating the expression of ABH antigens; preventing skin pore enlargement by providing antioxidant effects; and defending against skin irritation production and method of using the composition are disclosed.

公开(公告)号：US20150352037A1

公开(公告)日：2015-12-10

申请号：US14830005

申请日：2015-08-19

Applicant: Amorepacific Corporation

Inventor： Young Gyu KANG ,  Jun Seong PARK ,  Jee Yeun KIM ,  Yong Joo NA ,  Nok Hyun PARK ,  Myeong Hun YEOM ,  Jun Cheol CHO

IPC: A61K8/97 ,  A61Q19/08

CPC classification number: A61K8/97 ,  A61K2800/5922 ,  A61K2800/78 ,  A61Q19/08

Abstract: Provided are an anti-aging composition that contains a mixed extract of Chinese matrimony vine and pine needles as an effective component and a method of inhibiting aging of skin. The composition is for an external application to the skin, wherein a mixed extract of Chinese matrimony vine and pine needles, which are the natural ingredients, is contained such that excellent anti-aging or wrinkle improvement effects to the skin can be obtained through the vitalization of a retinoic acid derivative.

Abstract translation: 本发明提供一种抗老化组合物，其含有作为有效成分的中国结婚藤和松针的混合提取物以及抑制皮肤老化的方法。 该组合物用于对皮肤的外部应用，其中含有作为天然成分的中国结婚藤和松针的混合提取物，使得通过活化能够获得对皮肤的优异的抗衰老或皱纹改善效果 的视黄酸衍生物。

公开(公告)号：US20150184216A1

公开(公告)日：2015-07-02

申请号：US14588790

申请日：2015-01-02

Applicant: AMOREPACIFIC CORPORATION

Inventor： Jun Seong PARK ,  Duck Hee KIM ,  Han Kon KIM ,  Eun Mi KIM ,  Byung Gee KIM

IPC: C12P33/20 ,  C12P17/06

CPC classification number: C12P33/20 ,  C12N1/20 ,  C12N9/0004 ,  C12P17/06 ,  C12P19/02 ,  C12P33/00 ,  C12R1/41 ,  Y02P20/52

Abstract: The present invention relates to the novel Rhizobium sp. GIN611 KCTC11708BP or to cell extracts thereof, to a novel oxidoreductase which exhibits a glycolytic activity, to a gene encoding the oxidoreductase, to a recombinant strain comprising recombinant vector proteins or to an expression vector encoding recombinant proteins, and to a method for the glycolysis of natural products using same as a biocatalyst. The present invention also relates to a method for producing aglycones from a variety of natural products using same. The novel oxidoreductase separated from the novel microorganism of the present invention does not belong to a glucosidase group but belongs to an oxidoreductase group, and has a glycolytic activity for natural products. The novel oxidoreductase oxidizes the sugar in the aglycones of natural products, thereby producing a variety of aglycones.

Abstract translation: 本发明涉及新根瘤菌属（Rhizobium sp。） GIN611KCTC11708BP或其细胞提取物，对具有糖酵解活性的新型氧化还原酶，与编码该氧化还原酶的基因相连，包含重组载体蛋白的重组菌株或编码重组蛋白的表达载体，以及糖酵解方法 使用与生物催化剂相同的天然产物。 本发明还涉及使用它们的各种天然产物制备糖苷配基的方法。 从本发明的新型微生物分离的新型氧化还原酶不属于葡萄糖苷酶基团，属于氧化还原酶基团，对天然产物具有糖酵解活性。 新型氧化还原酶氧化天然产物的糖苷配基中的糖，从而产生各种糖苷配基。